Harkiran K Kooner, Maksym Sharma, Marrissa J McIntosh, Inderdeep Dhaliwal, J Michael Nicholson, Miranda Kirby, Sarah Svenningsen, Grace Parraga
RATIONALE AND OBJECTIVES: It remains difficult to predict longitudinal outcomes in long-COVID, even with chest CT and functional MRI. 129 Xe MRI reflects airway dysfunction, measured using ventilation defect percent (VDP) and in long-COVID patients, MRI VDP was abnormal, suggestive of airways disease. While MRI VDP and quality-of-life improved 15-month post-COVID infection, both remained abnormal. To better understand the relationship of airways disease and quality-of-life improvements in patients with long-COVID, we extracted 129 Xe ventilation MRI textures and generated machine-learning models in an effort to predict improved quality-of-life, 15-month post-infection...
April 17, 2024: Academic Radiology