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https://www.readbyqxmd.com/read/28338925/tobacco-use-oral-health-and-risk-of-parkinson-s-disease
#1
Zhiwei Liu, Ann Roosaar, Tony Axéll, Weimin Ye
Few studies have investigated the associations between use of Swedish moist snuff (snus), associated poor oral health, and risk of Parkinson's disease (PD). We followed 20,175 participants who were free of PD in 1973-1974 in Uppsala, Sweden, until the end of 2012. We used Cox proportional hazards regression models to estimate hazard ratios and corresponding 95% confidence intervals for the associations between tobacco use, oral health indicators, and PD risk. We found that tobacco use was associated with a lower risk of PD in males...
March 9, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28334654/synthesis-and-biological-evaluation-of-a-new-series-of-benzimidazole-derivatives-as-antimicrobial-antiquorum-sensing-and-antitumor-agents
#2
N S El-Gohary, M I Shaaban
New benzimidazole derivatives were synthesized and assessed for antimicrobial efficacy toward Escherichia coli, Bacillus cereus, Staphylococcus aureus, Candida albicans and Aspergillus fumigatus 293. Results indicated that compounds 3c and 3n have promising activity toward S. aureus, whereas 3i exhibited remarkable efficacy toward B. cereus. Moreover, compound 3c was proved to be the most active antifungal analog toward C. albicans. On the other hand, 3n displayed the highest activity against A. fumigatus 293...
March 14, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28327805/antifungal-activity-of-synthetic-antiseptics-and-natural-compounds-against-candida-dubliniensis-before-and-after-in-vitro-fluconazole-exposure
#3
Cássia Franco Reginato, Laíssa Arévalo Bandeira, Régis Adriel Zanette, Janio Morais Santurio, Sydney Hartz Alves, Cristiane Cademartori Danesi
INTRODUCTION: This study evaluated the susceptibilities of oral candidiasis-derived Candida albicans, fluconazole-resistant (FR) Candida dubliniensis, and fluconazole-susceptible (FS) C. dubliniensis to synthetic antiseptics [chlorhexidine gluconate (CHX), cetylpyridinium chloride (CPC), and triclosan (TRC)] and natural compounds (carvacrol, eugenol and thymol). METHODS: Susceptibility tests were performed based on the M27-A3 reference method. The fluconazole-resistant C...
January 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28326154/probiotic-lactobacillus-reuteri-has-antifungal-effects-on-oral-candida-species-in-vitro
#4
Mette Rose Jørgensen, Camilla Kragelund, Peter Østrup Jensen, Mette Kirstine Keller, Svante Twetman
Background: An alternative approach for managing Candida infections in the oral cavity by modulating the oral microbiota with probiotic bacteria has been proposed. Objective: The aim was to investigate the antifungal potential of the probiotic bacterium Lactobacillus reuteri (DSM 17938 and ATCC PTA 5289) against six oral Candida species (C. albicans, C. glabrata, C. krusei, C. tropicalis, C. dubliniensis, and C. parapsilosis). Design: The lactobacilli were tested for their ability to co-aggregate with and inhibit the growth of the yeasts assessed by spectrophotometry and the agar overlay inhibition assay...
2017: Journal of Oral Microbiology
https://www.readbyqxmd.com/read/28326152/candida-albicans-alters-the-bacterial-microbiome-of-early-in-vitro-oral-biofilms
#5
M M Janus, W Crielaard, C M C Volgenant, M H van der Veen, B W Brandt, B P Krom
The yeast Candida albicans is an oral commensal microorganism, occurring in the oral cavity of 50-70% of healthy individuals. Its effect on oral ecology has mostly been studied using dual-species models, which disregards the complex nature of oral biofilms. The aim of this study was to culture C. albicans in a complex model to study its effect on oral biofilms. Biofilms, inoculated using pooled stimulated saliva with or without addition of C. albicans, were grown under anaerobic, aerobic, or aerobic +5% CO2 conditions...
2017: Journal of Oral Microbiology
https://www.readbyqxmd.com/read/28325761/the-aryl-hydrocarbon-receptor-governs-epithelial-cell-invasion-during-oropharyngeal-candidiasis
#6
Norma V Solis, Marc Swidergall, Vincent M Bruno, Sarah L Gaffen, Scott G Filler
Oropharyngeal candidiasis (OPC), caused predominantly by Candida albicans, is a prevalent infection in patients with advanced AIDS, defects in Th17 immunity, and head and neck cancer. A characteristic feature of OPC is fungal invasion of the oral epithelial cells. One mechanism by which C. albicans hyphae can invade oral epithelial cells is by expressing the Als3 and Ssa1 invasins that interact with the epidermal growth factor receptor (EGFR) on epithelial cells and stimulate endocytosis of the organism. However, the signaling pathways that function downstream of EGFR and mediate C...
March 21, 2017: MBio
https://www.readbyqxmd.com/read/28317569/oral-fungal-infections-diagnosis-and-management
#7
REVIEW
David R Telles, Niraj Karki, Michael W Marshall
Oral and maxillofacial fungal infections can appear in high-risk patients, including those immunocompromised. This article explores common oral manifestations of fungal infections in the oral cavity as primary lesions or as a result of disseminated disease. By far the most common oral fungal infection experienced in dentistry is oral candidiasis, which is reviewed in depth from simple oral infections to invasive candidiasis. The review aids the dental practitioner in understanding the full scope of Candida infections and other fungal infections...
April 2017: Dental Clinics of North America
https://www.readbyqxmd.com/read/28315456/mechanisms-underlying-the-diuretic-effect-of-gomphrena-celosioides-mart-amaranthaceae
#8
Paulo Cesar de Paula Vasconcelos, Danilo Ramos Spessotto, Jane Vasconcelos Marinho, Marcos José Salvador, Arquimedes Gasparotto Junior, Candida Aparecida Leite Kassuya
ETHNOPHARMACOLOGICAL RELEVANCE: Gomphrena celosioides (Amaranthaceae) is a native medicinal plant found in Mato Grosso do Sul State that is used for treating urinary tract and kidney stones. This study aimed to evaluate the diuretic effects of ethanolic extract from G. celosioides (EEGC) on acute and extended diuresis to provide a pharmacological basis for its use in traditional medicine. AIM OF THE STUDY: To evaluate the diuretic and natriuretic activity of EEGC and its mechanism of action in an animal model...
March 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28303980/comparison-of-oral-candida-species-prevalence-and-carriage-among-gutka-chewers-and-betel-quid-chewers
#9
Tariq Abduljabbar, Mudassir Hussain, Tariq Adnan, Fahim Vohra, Fawad Javed
OBJECTIVE: To compare prevalence and carriage of Candida species among gutka-chewers and betel-quid-chewers. METHODS: The cross-sectional case-control study was conducted between January and December, 2015 at the Oral Surgery department of Abbasi Shaheed Hospital and the Dental department of Jinnah Postgraduate Medical Centre, Karachi, and comprised oral yeast samples of gutka-chewers, betel-quid-chewers, and non-chewers. A standardised questionnaire was used to gather demographic data and oral hygiene maintenance information...
March 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28303122/antifungal-drug-susceptibility-of-candida-species-isolated-from-hiv-positive-patients-recruited-at-a-public-hospital-in-s%C3%A3-o-lu%C3%A3-s-maranh%C3%A3-o-brazil
#10
Ana L G Terças, Sirlei G Marques, Eduardo B Moffa, Márcia B Alves, Conceição M P S de Azevedo, Walter L Siqueira, Cristina A Monteiro
Oropharyngeal candidiasis is the most common fungal infection in hospitalized patients with acquired immune deficiency syndrome (AIDS). Its progression results in invasive infections, which are a significant cause of morbidity and mortality. This study aimed to quickly and accurately identify Candida spp. from oral mucosa of AIDS patients recruited at Presidente Vargas Hospital, in São Luís city, Brazil and to evaluate the sensitivity profile of these fungi to antifungals by using an automated system. Isolates were collected from oropharyngeal mucosa of 52 hospitalized AIDS patients, under anti-viral and antifungal therapies...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28300045/-nature-cures-an-alternative-herbal-formulation-as-a-denture-cleanser
#11
R Sushma, Tanuja Tanaji Sathe, Anand Farias, Pronob Kumar Sanyal, Shashi Kiran
BACKGROUND: Candida albicans is one of the microorganisms which harbor the oral cavity, especially in elderly. However, the incidence of existence of this increases in patients using removable dental prosthesis. There is therefore a need to test the anticandidal efficacy of these cost-effective, easily available products to be used as routine denture cleansers. AIM AND OBJECTIVES: (1) To evaluate antifungal properties of triphala churna on the heat cure denture base material...
January 2017: Annals of African Medicine
https://www.readbyqxmd.com/read/28295299/oral-findings-and-dental-behaviour-before-and-after-liver-transplantation-a-single-centre-cross-sectional-study
#12
Anne Kauffels, Gerhard Schmalz, Otto Kollmar, Jan E Slotta, Michael Weig, Uwe Groß, Oliver Bader, Dirk Ziebolz
OBJECTIVE: The aim of this single-centre, cross-sectional study was to evaluate dental, periodontal and mycological findings, as well as oral behaviour, in patients before (pre-LTx) and after (post-LTx) liver transplantation. METHODS: A total of 47 patients pre-LTx and 119 patients post-LTx were asked to participate. Oral health behaviour was assessed using a standardised questionnaire. Oral examinations included dental [decayed, missing and filled teeth (DMFT) index] and periodontal [papillary bleeding index (PBI), periodontal probing depth (PPD) and clinical attachment loss (CAL)] findings...
March 10, 2017: International Dental Journal
https://www.readbyqxmd.com/read/28290221/microbiological-diagnosis-and-antimicrobial-sensitivity-profiles-in-diseased-free-living-raptors
#13
Anna Vidal, Laia Baldomà, Rafael A Molina-Lopez, Marga Martin, Laila Darwich
Free-living raptors (birds of prey) can act as reservoirs of potentially zoonotic agents but they also can be affected by microorganisms as target hosts. In this retrospective study, microbiological results (n=663) and antibiotic sensitivity profiles (n=108) of bacterial isolates were analyzed from diseased free-living raptors. Sixty-nine percent of cases (n=457) yielded bacteria: 58% were in pure culture and 42% were of different species. Remarkably, samples from necropsies (47%) had higher percentage of pure isolations than those obtained from clinical (31%) samples (p<0...
March 14, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28290130/the-choosing-wisely-initiative-in-infectious-diseases
#14
REVIEW
Clara Lehmann, Reinhard Berner, Johannes R Bogner, Oliver A Cornely, Katja de With, Susanne Herold, Winfried V Kern, Sebastian Lemmen, Mathias W Pletz, Bernhard Ruf, Bernd Salzberger, Hans Jürgen Stellbrink, Norbert Suttorp, Andrew J Ullmann, Gerd Fätkenheuer, Norma Jung
OBJECTIVE: "Choosing Wisely" is a growing international campaign aiming at practice changes to improve patient health and safety by both, conduct of essential and avoidance of unnecessary diagnostic, preventive and therapeutic procedures. The goal is to create an easily recognizable and distributable list ("Choosing Wisely items") that addresses common over- and underuse in the management of infectious diseases. METHODS: The German Society of Infectious Diseases (DGI) participates in the campaign "Klug Entscheiden" by the German Society of Internal Medicine...
March 13, 2017: Infection
https://www.readbyqxmd.com/read/28283094/the-relationship-of-candida-colonization-of-the-oral-and-vaginal-mucosae-of-mothers-and-oral-mucosae-of-their-newborns-at-birth
#15
Rund M Al-Rusan, Azmi M G Darwazeh, Isam M Lataifeh
OBJECTIVE: Vaginal Candida colonization is common during pregnancy. Vaginal Candida may transmit vertically to the mouth of newborns during labor. The aim of this study was to assess and compare oral Candida colonization between vaginally born newborns and cesarean-born newborns and to investigate the association of the mother's vaginal and oral Candida colonization and the newborn's oral colonization at the time of delivery. STUDY DESIGN: Culture swabs were collected from the oral and vaginal mucosae of 100 pregnant women and from the oral mucosa of their 100 full-term newborns...
April 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28280743/nicotine-enhances-interspecies-relationship-between-streptococcus-mutans-and-candida-albicans
#16
Shiyu Liu, Wei Qiu, Keke Zhang, Xuedong Zhou, Biao Ren, Jinzhi He, Xin Xu, Lei Cheng, Mingyun Li
Streptococcus mutans and Candida albicans are common microorganisms in the human oral cavity. The synergistic relationship between these two species has been deeply explored in many studies. In the present study, the effect of alkaloid nicotine on the interspecies between S. mutans and C. albicans is explored. We developed a dual-species biofilm model and studied biofilm biomass, biofilm structure, synthesis of extracellular polysaccharides (EPS), and expression of glucosyltransferases (Gtfs). Biofilm formation and bacterial and fungal cell numbers in dual-species biofilms increased in the presence of nicotine...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28274059/-rhetoric-to-reality-efficacy-of-punica-granatum-peel-extract-on-oral%C3%A2-candidiasis-an-in-vitro-study
#17
Preethi Madugula, Sudhakara Reddy, Jyothirmai Koneru, Atla Srinivasa Rao, Rayapureddi Sruthi, Divya Teja Dalli
INTRODUCTION: Global usage of synthetic drugs inadvertently has resulted in deleterious effects and antimicrobial resistance. Phytoextarcts with therapeutic properties appear to be appropriate substitutes for synthetic drugs. Punica granatum (Pomegranate) is a fruit rich in nutraceuticals and therapeutic properties that has lead to its widespread use as folk-medicine for treating innumerable diseases. AIM: To determine the in vitro antifungal efficacy of Punica granatum peel extract against the oral Candida compared with clotrimazole...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28271628/zinc-oxide-3d-microstructures-as-an-antimicrobial-filler-content-for-composite-resins
#18
Hércules Bezerra Dias, Maria Inês Basso Bernardi, Matheus Aparecido Dos Santos Ramos, Tamara Carolina Trevisan, Taís Maria Bauab, Antônio Carlos Hernandes, Alessandra Nara de Souza Rastelli
The aim of this study was to evaluate the antibacterial activity of a composite resin modified by 3D zinc oxide (ZnO) microstructures and to verify possible alterations on its mechanical properties. ZnO was synthesized by hydrothermal approach and characterized by X-ray diffraction (XRD), surface area by Brunauer, Emmett and Teller (BET), Fourier transform infrared spectroscopy (FTIR) and Field emission scanning electron microscopy (FESEM). The minimum inhibitory concentrations of ZnO against Streptococcus mutans, Escherichia coli, Staphylococcus aureus, and Candida albicans were determinated...
March 8, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28270852/effects-of-honey-on-oral-mucositis-among-pediatric-cancer-patients-undergoing-chemo-radiotherapy-treatment-at-king-abdulaziz-university-hospital-in-jeddah-kingdom-of-saudi-arabia
#19
Soad K Al Jaouni, Mohammad S Al Muhayawi, Abear Hussein, Iman Elfiki, Rajaa Al-Raddadi, Saad M Al Muhayawi, Saad Almasaudi, Mohammad Amjad Kamal, Steve Harakeh
One of the most common complications of cancer chemotherapy is oral mucositis. This study evaluates the therapeutic effects of honey with the focus on grade III and IV oral mucositis, reduction of bacterial and fungal infections, duration of episodes of oral mucositis, and body weight in pediatric leukemic patients undergoing chemo/radiotherapy. This is an open labeled randomized controlled study conducted at our hospital on 40 pediatric cancer patients undergoing chemo/radiotherapy. All the 40 patients included in this study experienced a sum total of 390 episodes of fever and neutropenia associated with oral mucositis...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28264651/interactions-of-histatin-3-and-histatin-5-with-actin
#20
Edna Blotnick, Asaf Sol, Gilad Bachrach, Andras Muhlrad
BACKGROUND: Histatins are histidine rich polypeptides produced in the parotid and submandibular gland and secreted into the saliva. Histatin-3 and -5 are the most important polycationic histatins. They possess antimicrobial activity against fungi such as Candida albicans. Histatin-5 has a higher antifungal activity than histatin-3 while histatin-3 is mostly involved in wound healing in the oral cavity. We found that these histatins, like other polycationic peptides and proteins, such as LL-37, lysozyme and histones, interact with extracellular actin...
March 6, 2017: BMC Biochemistry
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