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Elizabeth A Mazzio, Charles A Lewis, Karam F A Soliman
BACKGROUND/AIM: Triple-negative breast cancer (TNBC) is characterized by the absence of hormone receptors (estrogen, progesterone and human epidermal growth factor receptor-2) and a relatively poor prognosis due to inefficacy of hormone receptor-based chemotherapies. It is imperative that we continue to explore natural products with potential to impede growth and metastasis of TNBC. In this study, we screened over 1,000 natural products for capacity to induce cell death in TNBC (MDA-MB -231) cells...
November 2017: Cancer Genomics & Proteomics
Shih Ting Bai, Shu Hao Chang, Jing Min Duh, Fu Hsiang Sung, Jhen Sheng Su, Moo Been Chang
This study investigates the formation and removal of PCDD/Fs and dl-PCBs in two woodchips boilers during different operating periods. Results indicate that combustion condition affects PCDD/F and dl-PCB formation within the woodchip combustion process. PCDD/F and dl-PCB concentrations during the start-up period are much higher than those measured during normal operation and shut-down periods due to unstable combustion. PCDD/F and dl-PCB concentrations at APCDs inlet of Plant A are significantly higher than that of Plant B due to the lower combustion temperature (500-850 °C) compared with Plant B (850-925 °C)...
September 18, 2017: Chemosphere
Hu Bin, Yi Yang, Liang Cai, Yang Linjun, Szczepan Roszak
Desulfurization wastewater evaporation technology is used to enhance the removal of gaseous mercury (Hg) in conventional air pollution control devices (APCDs) for coal-fired power plants. It had been studied that gaseous Hg is oxidized and removed by selective catalytic reduction (SCR), an electrostatic precipitator (ESP) and a wet flue gas desulfurization (WFGD) in coal-fired thermal experiment platform with WFGD wastewater evaporation. Effects of desulfurization wastewater evaporation position, evaporation temperature, and chlorine ion concentration on Hg oxidation were studied as well...
September 15, 2017: Environmental Technology
Shilin Zhao, Yufeng Duan, Lei Chen, Yaning Li, Ting Yao, Shuai Liu, Meng Liu, Jianhong Lu
Hazardous trace elements (HTEs), especially mercury, emitted from coal-fired power plants had caused widespread concern worldwide. Field test on mercury emissions at three different loads (100%, 85%, 68% output) using different types of coal was conducted in a 350 MW pulverized coal combustion power plant equipped with selective catalytic reduction (SCR), electrostatic precipitator and fabric filter (ESP + FF), and wet flue gas desulfurization (WFGD). The Ontario Hydro Method was used for simultaneous flue gas mercury sampling for mercury at the inlet and outlet of each of the air pollutant control device (APCD)...
October 2017: Environmental Pollution
Jose F Figueroa, Austin B Frakt, Zoe M Lyon, Xiner Zhou, Ashish K Jha
BACKGROUND: Given that health care costs in Massachusetts continue to grow despite great efforts to contain them, we seek to understand characteristics and spending patterns of the costliest non-elderly adults in Massachusetts based on type of insurance. METHODS: We used the Massachusetts All-Payer Claims Database (APCD) from 2012 and analyzed demographics, utilization patterns and spending patterns across payers (Medicaid, Medicaid managed care, and private insurers) for high cost patients (those in the top 10% of spending) and non-high cost patients (the remaining 90%)...
June 21, 2017: Healthcare
Qian-Zhao Xu, Qi-Ying Tang, Jia-Xin Han, Wen-Long Ding, Bao-Qing Zhao, Ming Zhou, Wolfgang Gärtner, Hugo Scheer, Kai-Hong Zhao
Cyanobacterial phycobilisomes funnel the harvested light energy to the reaction centers via two terminal emitters, allophycocyanin B and the core-membrane linker. ApcD is the α-subunit of allophycocyanin B responsible for its red-shifted absorbance (λmax 665 nm). Far-red photo-acclimated cyanobacteria contain certain allophycocyanins that show even further red-shifted absorbances (λmax > 700 nm). We studied the chromophorylation of the three far-red induced ApcD subunits ApcD2, ApcD3 and ApcD4 from Chroococcidiopsis thermalis sp...
July 1, 2017: Photochemical & Photobiological Sciences
Shilin Zhao, Yufeng Duan, Lei Chen, Yaning Li, Ting Yao, Shuai Liu, Meng Liu, Jianhong Lu
Hazardous Trace elements (HTEs) emitted from coal combustion has raised widespread concern. Studies on the emission characteristics of five HTEs, namely arsenic (As), chromium (Cr), barium (Ba), manganese (Mn), lead (Pb) at three different loads (100%, 83%, 71% output) and different coal types were performed on a 350 MW coal-fired power plant equipped with SCR, ESP + FF, and WFGD. HTEs in the flue gas at the inlet/outlet of each air pollution control device (APCD) were sampled simultaneously based on US EPA Method 29...
July 2017: Environmental Pollution
Dmitry V Zlenko, Tatiana V Galochkina, Pavel M Krasilnikov, Igor N Stadnichuk
Phycobilisome (PBS) is a giant water-soluble photosynthetic antenna transferring the energy of absorbed light mainly to the photosystem II (PSII) in cyanobacteria. Under the low light conditions, PBSs and PSII dimers form coupled rows where each PBS is attached to the cytoplasmic surface of PSII dimer, and PBSs come into contact with their face surfaces (state 1). The model structure of the PBS core that we have developed earlier by comparison and combination of different fine allophycocyanin crystals, as reported in Zlenko et al...
September 2017: Photosynthesis Research
Paul Enck, Ursula Koehler, Harald Weigmann, Stefan Mueller-Lissner
Background Abdominal pain, cramping, and discomfort (APCD) are experienced by up to 30 % of adults in Europe. Objective To assess the impact of APCD on quality of life (QoL) and to investigate the effectiveness, tolerability, and impact on QoL of hyoscine butylbromide (HBB, Buscopan(®)) compared with STW 5 (Iberogast(®)) or analgesics in women with APCD. Methods An internet-based observational pilot study was conducted in Germany in women who had predominantly used HBB, STW 5, or analgesics (n = 240 per treatment) to treat APCD...
March 2017: Zeitschrift Für Gastroenterologie
Tianjiao Wang, Tong Chen, Xiaoqing Lin, Mingxiu Zhan, Xiaodong Li
The concentrations, homologue, and congener profiles, as well as the gas/particle distribution of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs), chlorobenzenes (CBzs), chlorophenols (CPhs), and polyaromatic hydrocarbons (PAHs) from stack gas of two different municipal solid waste incinerators in China, were characterized. The incinerators were a stoker furnace incinerator equipped with the advanced air pollution control device (APCD) and a common circulating fluidized bed (CFB) furnace. The concentration of PCDD/Fs in the stack gas of the stoker incinerator ranged 0...
February 2017: Environmental Science and Pollution Research International
Philip Rocco, Andrew S Kelly, Daniel Béland, Michael Kinane
Prices are a significant driver of health care cost in the United States. Existing research on the politics of health system reform has emphasized the limited nature of policy entrepreneurs' efforts at solving the problem of rising prices through direct regulation at the state level. Yet this literature fails to account for how change agents in the states gradually reconfigured the politics of prices, forging new, transparency-based policy instruments called all-payer claims databases (APCDs), which are designed to empower consumers, purchasers, and states to make informed market and policy choices...
February 2017: Journal of Health Politics, Policy and Law
Ruwei Wang, Balal Yousaf, Ruoyu Sun, Hong Zhang, Jiamei Zhang, Guijian Liu
The objective of this study was to characterize parent polycyclic aromatic hydrocarbons (pPAHs) and their nitrated derivatives (NPAHs) in coarse (PM2.5-10), intermediate (PM1-2.5) and fine (PM1) particulate matters emitted from coal-fired power plants (CFPPs) in Huainan, China. The diagnostic ratios and the stable carbon isotopic approaches to characterize individual PAHs were applied in order to develop robust tools for tracing the origins of PAHs in different size-segregated particular matters (PMs) emitted CFPP coal combustion...
November 15, 2016: Journal of Hazardous Materials
Louis Chauvel, Anja K Leist, Valentina Ponomarenko
Birth cohort effects in suicide rates are well established, but to date there is no methodological approach or framework to test the temporal stability of these effects. We use the APC-Detrended (APCD) model to robustly estimate intensity of cohort effects identifying non-linear trends (or 'detrended' fluctuations) in suicide rates. The new APC-Hysteresis (APCH) model tests temporal stability of cohort effects. Analysing suicide rates in 25 WHO countries (periods 1970-74 to 2005-09; ages 20-24 to 70-79) with the APCD method, we find that country-specific birth cohort membership plays an important role in suicide rates...
2016: PloS One
Fernando Delgado, Isabel Bravo, Elvira Jiménez, Eduardo Murías, Antonio Saiz, Pedro Vega, Antonio López-Rueda, Jordi Blasco, Juan Macho, Alejandro González
BACKGROUND: Carotid dissection (CD) may, in certain cases, lead to significant stenosis, occlusion, or pseudoaneurysm formation, causing embolic stroke or hemodynamic failure, despite medical therapy. OBJECTIVE: To evaluate the results of endovascular treatment and clinical outcomes of patients with CD. METHODS: A four-hospital retrospective study of endovascular treatment of extracranial CD in which medical treatment had failed or patients presented with a National Institute of Health Stroke Scale (NIHSS) score ≥8...
January 2017: Journal of Neurointerventional Surgery
Yuancheng Li, Yang Yang, Gang Yu, Jun Huang, Bin Wang, Shubo Deng, Yujue Wang
Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), polychlorinated biphenyls (PCBs), pentachlorobenzene (PeCBz) and hexachlorobenzene (HxCBz), which are listed in the Stockholm Convention, are commonly known as unintentionally produced persistent organic pollutants (UPOPs). As municipal waste incinerators (MWIs) have burgeoned in China, the emission of UPOPs is of great concerns. Compared to the extensive studies of PCDD/Fs emission, not much information of non-dioxin UPOPs (i.e., PCBs, HxCBz, and PeCBz) is available...
September 2016: Chemosphere
Mei-Chen Liu, Shu-Hao Chang, Moo-Been Chang
A continuous pyrolysis system (CPS) with effective air pollution control devices (APCDs) is designed and constructed to remediate the soil containing high-concentration PCDD/Fs. The quench tower of the APCDs system can capture the pollutants of high boiling points from the flue gas of CPS and produces condensed water of high PCDD/Fs concentration (16-44 ng I-TEQ/L), and needs further treatment. First, the result of activated carbon adsorption test displays the PCDD/Fs toxicity concentration of effluents meet the regulatory standards as the liquid to solid ratio is controlled at 3: 1...
July 2016: Chemosphere
Buddhika T B Wijerathne, Robert J Meier, Sujatha S Salgado, Suneth B Agampodi
Kidney diseases are becoming a major cause of global burden with high mortality and morbidity. The origins of most kidney diseases are known, but for some the exact aetiology is not yet understood. Dermatoglyphics is the scientific study of epidermal ridge patterns and it has been used as a non-invasive diagnostic tool to detect or predict different medical conditions that have foetal origin. However, there have been a limited number of studies that have evaluated a dermatoglyphic relationship in different kidney diseases...
2016: SpringerPlus
Wen-hua Yin, Xiao-wei Yu, Jing-lei Han, Gui-xian Feng, Jian-ping Fu, Yan-yan Yang, Yong-ming Ju, Su-kun Zhang
To analysis the influencing factors for the emssions of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) as structure of crematory, air pollution control device (APCD) and funeral objects, etc, we collected and measured the PCDD/Fs emissions in flue gas from 13 crematories in China. Then we proposed some supervision suggestions on measures of pollution control and management. The results indicated that the emission levels of PCDD/Fs (as the toxic equivalent concentration, TEQ) was ranged in a large gap from 0...
October 2015: Huan Jing Ke Xue= Huanjing Kexue
Pinar Karaca-Mandic, Alan T Hirsch, Stanley G Rockson, Sheila H Ridner
IMPORTANCE: The prevalence and clinical burden of lymphedema is known to be increasing. Nevertheless, evidence-based comparative effectiveness data regarding lymphedema therapeutic interventions have been poor. OBJECTIVE: To examine the impact of an advanced pneumatic compression device (APCD) on cutaneous and other clinical outcomes and health economic costs in a representative privately insured population of lymphedema patients. DESIGN, SETTING, AND PARTICIPANTS: Retrospective analysis of a deidentified private insurance database from 2007 through 2013, and multivariate regression analysis comparing outcomes for the 12 months before and after APCD purchase, adjusting for baseline patient characteristics...
November 2015: JAMA Dermatology
Mayumi Takano, Hiroko Hirata, Yukiko Kagawa, Susumu Murata, Michihisa Fujiwara, Masahiko Nakata
AIM: Cerebellar hypoplasia, particularly, trisomy 18, represents a chromosomal abnormality. However, morphological assessment of the fetal cerebellum is yet to be established. The purpose of this study was to produce reference values for the fetal transverse cerebellar diameter (TCD), anteroposterior cerebellar diameter (APCD) and the ratio of APCD to TCD (APCD/TCD ratio) in normal fetuses, compared with cases of trisomy 18. METHODS: This retrospective study included 266 normal singleton pregnancies resulting in term delivery at our institution from 2012-2013...
November 2015: Journal of Obstetrics and Gynaecology Research
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