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Philip Rocco, Andrew S Kelly, Daniel Béland, Michael Kinane
Prices are a significant driver of health care cost in the United States. Existing research on the politics of health system reform has emphasized the limited nature of policy entrepreneurs' efforts at solving the problem of rising prices through direct regulation at the state level. Yet this literature fails to account for how change agents in the states gradually reconfigured the politics of prices, forging new, transparency-based policy instruments called all-payer claims databases (APCDs), which are designed to empower consumers, purchasers, and states to make informed market and policy choices...
October 11, 2016: Journal of Health Politics, Policy and Law
Ruwei Wang, Balal Yousaf, Ruoyu Sun, Hong Zhang, Jiamei Zhang, Guijian Liu
The objective of this study was to characterize parent polycyclic aromatic hydrocarbons (pPAHs) and their nitrated derivatives (NPAHs) in coarse (PM2.5-10), intermediate (PM1-2.5) and fine (PM1) particulate matters emitted from coal-fired power plants (CFPPs) in Huainan, China. The diagnostic ratios and the stable carbon isotopic approaches to characterize individual PAHs were applied in order to develop robust tools for tracing the origins of PAHs in different size-segregated particular matters (PMs) emitted CFPP coal combustion...
November 15, 2016: Journal of Hazardous Materials
Louis Chauvel, Anja K Leist, Valentina Ponomarenko
Birth cohort effects in suicide rates are well established, but to date there is no methodological approach or framework to test the temporal stability of these effects. We use the APC-Detrended (APCD) model to robustly estimate intensity of cohort effects identifying non-linear trends (or 'detrended' fluctuations) in suicide rates. The new APC-Hysteresis (APCH) model tests temporal stability of cohort effects. Analysing suicide rates in 25 WHO countries (periods 1970-74 to 2005-09; ages 20-24 to 70-79) with the APCD method, we find that country-specific birth cohort membership plays an important role in suicide rates...
2016: PloS One
Fernando Delgado, Isabel Bravo, Elvira Jiménez, Eduardo Murías, Antonio Saiz, Pedro Vega, Antonio López-Rueda, Jordi Blasco, Juan Macho, Alejandro González
BACKGROUND: Carotid dissection (CD) may, in certain cases, lead to significant stenosis, occlusion, or pseudoaneurysm formation, causing embolic stroke or hemodynamic failure, despite medical therapy. OBJECTIVE: To evaluate the results of endovascular treatment and clinical outcomes of patients with CD. METHODS: A four-hospital retrospective study of endovascular treatment of extracranial CD in which medical treatment had failed or patients presented with a National Institute of Health Stroke Scale (NIHSS) score ≥8...
July 15, 2016: Journal of Neurointerventional Surgery
Yuancheng Li, Yang Yang, Gang Yu, Jun Huang, Bin Wang, Shubo Deng, Yujue Wang
Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), polychlorinated biphenyls (PCBs), pentachlorobenzene (PeCBz) and hexachlorobenzene (HxCBz), which are listed in the Stockholm Convention, are commonly known as unintentionally produced persistent organic pollutants (UPOPs). As municipal waste incinerators (MWIs) have burgeoned in China, the emission of UPOPs is of great concerns. Compared to the extensive studies of PCDD/Fs emission, not much information of non-dioxin UPOPs (i.e., PCBs, HxCBz, and PeCBz) is available...
September 2016: Chemosphere
Mei-Chen Liu, Shu-Hao Chang, Moo-Been Chang
A continuous pyrolysis system (CPS) with effective air pollution control devices (APCDs) is designed and constructed to remediate the soil containing high-concentration PCDD/Fs. The quench tower of the APCDs system can capture the pollutants of high boiling points from the flue gas of CPS and produces condensed water of high PCDD/Fs concentration (16-44 ng I-TEQ/L), and needs further treatment. First, the result of activated carbon adsorption test displays the PCDD/Fs toxicity concentration of effluents meet the regulatory standards as the liquid to solid ratio is controlled at 3: 1...
July 2016: Chemosphere
Buddhika T B Wijerathne, Robert J Meier, Sujatha S Salgado, Suneth B Agampodi
Kidney diseases are becoming a major cause of global burden with high mortality and morbidity. The origins of most kidney diseases are known, but for some the exact aetiology is not yet understood. Dermatoglyphics is the scientific study of epidermal ridge patterns and it has been used as a non-invasive diagnostic tool to detect or predict different medical conditions that have foetal origin. However, there have been a limited number of studies that have evaluated a dermatoglyphic relationship in different kidney diseases...
2016: SpringerPlus
Wen-hua Yin, Xiao-wei Yu, Jing-lei Han, Gui-xian Feng, Jian-ping Fu, Yan-yan Yang, Yong-ming Ju, Su-kun Zhang
To analysis the influencing factors for the emssions of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) as structure of crematory, air pollution control device (APCD) and funeral objects, etc, we collected and measured the PCDD/Fs emissions in flue gas from 13 crematories in China. Then we proposed some supervision suggestions on measures of pollution control and management. The results indicated that the emission levels of PCDD/Fs (as the toxic equivalent concentration, TEQ) was ranged in a large gap from 0...
October 2015: Huan Jing Ke Xue= Huanjing Kexue
Pinar Karaca-Mandic, Alan T Hirsch, Stanley G Rockson, Sheila H Ridner
IMPORTANCE: The prevalence and clinical burden of lymphedema is known to be increasing. Nevertheless, evidence-based comparative effectiveness data regarding lymphedema therapeutic interventions have been poor. OBJECTIVE: To examine the impact of an advanced pneumatic compression device (APCD) on cutaneous and other clinical outcomes and health economic costs in a representative privately insured population of lymphedema patients. DESIGN, SETTING, AND PARTICIPANTS: Retrospective analysis of a deidentified private insurance database from 2007 through 2013, and multivariate regression analysis comparing outcomes for the 12 months before and after APCD purchase, adjusting for baseline patient characteristics...
November 2015: JAMA Dermatology
Mayumi Takano, Hiroko Hirata, Yukiko Kagawa, Susumu Murata, Michihisa Fujiwara, Masahiko Nakata
AIM: Cerebellar hypoplasia, particularly, trisomy 18, represents a chromosomal abnormality. However, morphological assessment of the fetal cerebellum is yet to be established. The purpose of this study was to produce reference values for the fetal transverse cerebellar diameter (TCD), anteroposterior cerebellar diameter (APCD) and the ratio of APCD to TCD (APCD/TCD ratio) in normal fetuses, compared with cases of trisomy 18. METHODS: This retrospective study included 266 normal singleton pregnancies resulting in term delivery at our institution from 2012-2013...
November 2015: Journal of Obstetrics and Gynaecology Research
Kei Hayata, Yuji Hiramatsu, Hisashi Masuyama, Eriko Etou, Etsuko Nobumoto, Takashi Mitsui
AIM: We created a new reference standard focusing on the hemispheric anteroposterior cerebellar diameter (APCD) in addition to the transverse cerebellar diameter (TCD) and discussed whether or not the cerebellar measurement was useful for the detection of trisomy 18 (T18). MATERIAL AND METHODS: In 150 normal fetuses between 14 and 36 weeks of gestational age (GA), the TCD and APCD were prospectively measured. In 26 cases with T18, the value was compared with the control...
December 2015: Journal of Obstetrics and Gynaecology Research
Annette Zeyner, Susanne Kirchhof, A Susenbeth, K-H Südekum, Ellen Kienzle
Few data on apparent pre-caecal digestibility (APCD) of crude protein (CP) and particularly amino acids (AA) are available from studies with horses. Protein bound in cell walls (i.e. neutral detergent insoluble CP (NDICP)) is unlikely to be decomposed by digestive enzymes in the small intestine. In contrast the corresponding analytical fraction of neutral detergent soluble CP (NDSCP) (NDSCP = CP-NDICP) is likely to be available for auto-enzymatic digestion. A literature analysis on the relationship between NDICP/NDSCP and pre-caecal indigestible/digestible CP was carried out...
2015: Journal of Nutritional Science
Shari Sellers, Walter Horodnik, Aileen House, Jennifer Wylie, Peter Mauser, Natalie Garber, Yu Elaine Pu, Julianne Berry, Brent Donovan
CONTEXT: Aerosol delivery to animals in preclinical settings has historically been very challenging, requiring the use of techniques, such as intratracheal instillation and dry powder insufflation, that are somewhat invasive, inefficient and not representative of clinical inhalation. OBJECTIVE: The objective of this work is to develop a system to deliver dry powder to dogs in an efficient and effective manner for the study of new anti-migraine compounds in development...
2015: Drug Development and Industrial Pharmacy
E G Maksimov, K E Klementiev, E A Shirshin, G V Tsoraev, I V Elanskaya, V Z Paschenko
Under high photon flux density of solar radiation, the photosynthetic apparatus can be damaged. To prevent this photodestruction, cyanobacteria developed special mechanisms of non-photochemical quenching (NPQ) of excitation energy in phycobilisomes. In Synechocystis, NPQ is triggered by the orange carotenoid protein (OCP), which is sensitive to blue-green illumination allowing it to bind to the phycobilisome reducing the flow of energy to the photosystems. Consequent decoupling of OCP and recovery of phycobilisome fluorescence in vivo is controlled by the so called fluorescence recovery protein (FRP)...
August 2015: Photosynthesis Research
Hüseyin Sinan Topçuoğlu, Sezer Demirbuga, Kansad Pala, Muhammed Cayabatmaz, Gamze Topçuoğlu
The optimal bonding of adhesives to dentin requires the sealer to be completely removed from dentinal walls. The aim of this study was to investigate the effect of different cleaning procedures using gutta-percha solvents on bond strength of adhesive resins to AH Plus contaminated dentin (APCD). The pulp chamber dentin surfaces were contaminated with AH Plus and cleaned with five different techniques (dry cotton, chloroform, orange oil, eucalyptol, and ethanol). Then, Clearfil SE Bond (CSE) (Kuraray), and Tetric N Bond (TNB) (Ivoclar Vivadent) were applied and filled with a composite resin...
March 2015: Scanning
Ran Mo, Mingkun Yang, Zhuo Chen, Zhongyi Cheng, Xingling Yi, Chongyang Li, Chenliu He, Qian Xiong, Hui Chen, Qiang Wang, Feng Ge
Cyanobacteria are the oldest known life form inhabiting Earth and the only prokaryotes capable of performing oxygenic photosynthesis. Synechocystis sp. PCC 6803 (Synechocystis) is a model cyanobacterium used extensively in research on photosynthesis and environmental adaptation. Posttranslational protein modification by lysine acetylation plays a critical regulatory role in both eukaryotes and prokaryotes; however, its extent and function in cyanobacteria remain unexplored. Herein, we performed a global acetylome analysis on Synechocystis through peptide prefractionation, antibody enrichment, and high accuracy LC-MS/MS analysis; identified 776 acetylation sites on 513 acetylated proteins; and functionally categorized them into an interaction map showing their involvement in various biological processes...
February 6, 2015: Journal of Proteome Research
Pan Pan Peng, Liang Liang Dong, Ya Fang Sun, Xiao Li Zeng, Wen Long Ding, Hugo Scheer, Xiaojing Yang, Kai Hong Zhao
Allophycocyanin B (AP-B) is one of the two terminal emitters in phycobilisomes, the unique light-harvesting complexes of cyanobacteria and red algae. Its low excitation-energy level and the correspondingly redshifted absorption and fluorescence emission play an important role in funnelling excitation energy from the hundreds of chromophores of the extramembraneous phycobilisome to the reaction centres within the photosynthetic membrane. In the absence of crystal structures of these low-abundance terminal emitters, the molecular basis for the extreme redshift and directional energy transfer is largely unknown...
October 2014: Acta Crystallographica. Section D, Biological Crystallography
Charles Sabbagh, François Mauvais, Cyril Cosse, Lionel Rebibo, Jean-Paul Joly, Didier Dromer, Christine Aubert, Sophie Carton, Bernard Dron, Innocenti Dadamessi, Bernard Maes, Guillaume Perrier, David Manaouil, Jean-François Fontaine, Michel Gozy, Xavier Panis, Pierre Henri Foncelle, Hugues de Fresnoy, Fabien Leroux, Pierre Vaneslander, Caroline Ghighi, Jean-Marc Regimbeau
Lymph node ratio (LNR) (positive lymph nodes/sampled lymph nodes) is predictive of survival in colon cancer. The aim of the present study was to validate the LNR as a prognostic factor and to determine the optimum LNR cutoff for distinguishing between "good prognosis" and "poor prognosis" colon cancer patients. From January 2003 to December 2007, patients with TNM stage III colon cancer operated on with at least of 3 years of follow-up and not lost to follow-up were included in this retrospective study. The two primary endpoints were 3-year overall survival (OS) and disease-free survival (DFS) as a function of the LNR groups and the cutoff...
July 2014: International Surgery
Renu Wickremasinghe, Sumadhya Deepika Fernando, Janani Thillekaratne, Panduka Mahendra Wijeyaratne, Ananda Rajitha Wickremasinghe
BACKGROUND: With the aim of eliminating malaria from Sri Lanka by 2014, the Anti-Malaria Campaign of Sri Lanka (AMC) sought the support of Tropical and Environmental Disease and Health Associates Private Limited (TEDHA), a private sector organization. In 2009, TEDHA was assigned 43 government hospitals in the district of Mannar in the Northern Province and in districts of Trincomalee, Batticaloa and Ampara in the Eastern Province to carry out malaria surveillance to complement the surveillance activities of the AMC...
2014: Malaria Journal
Hannu Savolainen, Iris Baumgartner, Juerg Schmidli, George Heller, Do-Dai Do, Torsten Willenberg
BACKGROUND: Despite use of arterial closure devices (APCDs) and thrombin injection , surgery is needed at times to repair femoral pseudoaneurysms (FPA) in patients undergoing endovascular interventions. We analysed the indications and results of surgical repair in a tertiary referral center performing more than 6.000 angiographies and/or interventions annually. OBJECTIVES: The aim of this retrospective observational study was to identify local and clinical factors related to the need of surgical repair...
January 2012: Trauma Monthly
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