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https://www.readbyqxmd.com/read/28918387/prospective-comparative-effectiveness-cohort-study-comparing-two-models-of-advance-care-planning-provision-for-australian-community-aged-care-clients
#1
Karen Margaret Detering, Rachel Zoe Carter, Marcus William Sellars, Virginia Lewis, Elizabeth Anne Sutton
OBJECTIVES: Conduct a prospective comparative effectiveness cohort study comparing two models of advance care planning (ACP) provision in community aged care: ACP conducted by the client's case manager (CM) ('Facilitator') and ACP conducted by an external ACP service ('Referral') over a 6-month period. METHODS: This Australian study involved CMs and their clients. Eligible CM were English speaking, ≥18 years, had expected availability for the trial and worked ≥3 days per week...
September 16, 2017: BMJ Supportive & Palliative Care
https://www.readbyqxmd.com/read/28917592/prefrontal-versus-motor-cortex-transcranial-direct-current-stimulation-tdcs-effects-on-post-surgical-opioid-use
#2
Jeffrey J Borckardt, Scott T Reeves, Cole Milliken, Brittan Carter, Thomas I Epperson, Ryan J Gunselman, Alok Madan, H Del Schutte, Harry A Demos, Mark S George
BACKGROUND: Pain is often a complaint that precedes total knee arthroplasty (TKA), however the procedure itself is associated with considerable post-operative pain lasting days to weeks which can predict longer-term surgical outcomes. Previously, we reported significant opioid-sparing effects of motor cortex transcranial direct current stimulation from a single-blind trial. In the present study, we used double-blind methodology to compare motor cortex tDCS and prefrontal cortex tDCS to both sham and active-control (active electrodes over non-pain modulating brain areas) tDCS...
September 6, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28911288/impact-of-thrombelastography-in-paediatric-intensive-care
#3
B G Carter, E Carland, P Monagle, S B Horton, W Butt
We assessed the clinical impact of thrombelastography (TEG®) results (TEG® 5000, Haemonetics Corporation, Braintree, MA, USA) by measuring their ability to cause changes in a theoretical treatment plan and contribute to the understanding of haemostasis. We prospectively included paediatric intensive care unit (PICU) patients who had standard tests of haemostasis and TEG ordered and had an arterial catheter or extracorporeal access port in situ. Blood for standard tests and TEG was taken simultaneously. Independent of patient care, general patient information and results of standard laboratory tests were presented to five clinicians who were asked to document their theoretical treatment plan...
September 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28910312/i%C3%AE%C2%BAk-16-decreases-mirna-155-expression-and-attenuates-the-human-monocyte-inflammatory-response
#4
Norman James Galbraith, James Burton, Mathew Brady Ekman, Joseph Kenney, Samuel Patterson Walker, Stephen Manek, Campbell Bishop, Jane Victoria Carter, Sarah Appel Gardner, Hiram C Polk
Excessive inflammatory responses in the surgical patient may result in cellular hypo-responsiveness, which is associated with an increased risk of secondary infection and death. microRNAs (miRNAs), such as miR-155, are powerful regulators of inflammatory signalling pathways including nuclear factor κB (NFκB). Our objective was to determine the effect of IκK-16, a selective blocker of inhibitor of kappa-B kinase (IκK), on miRNA expression and the monocyte inflammatory response. In a model of endotoxin tolerance using primary human monocytes, impaired monocytes had decreased p65 expression with suppressed TNF-α and IL-10 production (P < 0...
2017: PloS One
https://www.readbyqxmd.com/read/28890936/object-play-in-infants-with-autism-spectrum-disorder-a-longitudinal-retrospective-video-analysis
#5
Kaitlyn P Wilson, Mary W Carter, Heather L Wiener, Margaret L DeRamus, John C Bulluck, Linda R Watson, Elizabeth R Crais, Grace T Baranek
BACKGROUND AND AIMS: Early play behaviors may provide important information regarding later-diagnosed developmental delays. Play behaviors of young children with autism spectrum disorder (ASD) are restricted in diversity, frequency, and complexity. Most ASD research focuses on play in children over 18 months of age. This study examined three groups of infants (later diagnosed with ASD, later diagnosed with other developmental disorders, and typically developing) with the aims of: (1) describing the play behaviors of the three groups of infants at two time points (9-12 months and 15-18 months); (2) examining group differences in four hierarchical levels of play at both time points; (3) comparing groups with respect to the highest level of play achieved; and (4) determining if the highest level of play achieved by infants with developmental delays, including ASD, correlated with later developmental outcomes...
January 2017: Autism Dev Lang Impair
https://www.readbyqxmd.com/read/28889173/the-impact-of-fellowship-surgical-training-on-operative-time-and-patient-morbidity-during-robotics-assisted-sacrocolpopexy
#6
Charelle M Carter-Brooks, Angela L Du, Michael J Bonidie, Jonathan P Shepherd
INTRODUCTION AND HYPOTHESIS: Abdominal sacrocolpopexy is commonly performed for the surgical correction of pelvic organ prolapse (POP) in the USA. Over the last decade, fellowship programs have increased the number of these procedures performed robotically. Currently, there is a paucity of literature exploring the impact of fellowship training on outcomes of robotic-assisted sacrocolpopexy (RASC). We sought to explore the impact of an expert surgeon operating alone versus with a fellow on operative time and perioperative morbidity associated with RASC...
September 9, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28888843/food-protein-induced-enterocolitis-syndrome-to-peanut-with-early-introduction-a-clinical-dilemma
#7
Karen A Robbins, Olivia R Ackerman, Cristina A Carter, Burcin Uygungil, Anna Sprunger, Hemant P Sharma
No abstract text is available yet for this article.
September 6, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28888502/health-literacy-in-adolescents-with-sickle-cell-disease
#8
Elizabeth L Perry, Patricia A Carter, Heather A Becker, Alexandra A Garcia, Michael Mackert, Karen E Johnson
PURPOSE: To evaluate health literacy in a cohort of 75 adolescents with sickle cell disease (SCD). DESIGN AND METHODS: This cross-sectional, descriptive correlational study included assessment of demographic measures and appraisal of data resulting from completion of the REALM-Teen and Newest Vital Sign (NVS) instruments by 75 Black, non-Hispanic adolescents with SCD. Convenience sampling was utilized. Inclusion criteria were a diagnosis of one of the four primary genotypes of SCD and age 10-19years...
September 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28886596/assessing-exposure-to-household-air-pollution-a-systematic-review-and-pooled-analysis-of-carbon-monoxide-as-a-surrogate-measure-of-particulate-matter
#9
REVIEW
Ellison Carter, Christina Norris, Kathie L Dionisio, Kalpana Balakrishnan, William Checkley, Maggie L Clark, Santu Ghosh, Darby W Jack, Patrick L Kinney, Julian D Marshall, Luke P Naeher, Jennifer L Peel, Sankar Sambandam, James J Schauer, Kirk R Smith, Blair J Wylie, Jill Baumgartner
BACKGROUND: Household air pollution from solid fuel burning is a leading contributor to disease burden globally. Fine particulate matter (PM2.5) is thought to be responsible for many of these health impacts. A co-pollutant, carbon monoxide (CO) has been widely used as a surrogate measure of PM2.5 in studies of household air pollution. OBJECTIVE: The goal was to evaluate the validity of exposure to CO as a surrogate of exposure to PM2.5 in studies of household air pollution and the consistency of the PM2...
July 28, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28885941/the-impact-of-vaccine-refusal-on-physician-office-visits-during-the-subsequent-12-months
#10
Milissa U Jones, Cassandra G Carter, Kenneth L Cameron, Tyler K Smith
We hypothesized that families who are nonadherent to the routine vaccination schedule (RVS) present less frequently for physician visits. We conducted a retrospective chart review to compare the number of visits made over the subsequent 12-month period by families that refused the RVS versus those who were adherent. Subjects were aged 0 to 4 years, enrolled to Keller Army Hospital, and had a diagnosis indicating the RVS was refused. Age-matched controls, who were adherent to the RVS, were randomly chosen for each case...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28876332/zinc-and-multivitamin-supplementation-have-contrasting-effects-on-infant-iron-status-a-randomized-double-blind-placebo-controlled-clinical-trial
#11
R C Carter, R Kupka, K Manji, C M McDonald, S Aboud, J G Erhardt, K Gosselin, R Kisenge, E Liu, W Fawzi, C P Duggan
BACKGROUND/OBJECTIVES: Zinc (Zn) supplementation adversely affects iron status in animal and adult human studies, but few trials have included young infants. The objective of this study was to determine the effects of Zn and multivitamin (MV) supplementation on infant hematologic and iron status. SUBJECTS/METHODS: In a double-blind RCT, Tanzanian infants were randomized to daily, oral Zn, MV, Zn and MV or placebo treatment arms at the age of 6 weeks of life. Hemoglobin concentration (Hb) and red blood cell indices were measured at baseline and at 6, 12 and 18 months of age...
September 6, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28873060/a-retrospective-crossover-study-of-the-use-of-aseptically-processed-placental-membrane-in-the-treatment-of-chronic-diabetic-foot-ulcers
#12
Lawrence A DiDomenico, Dennis P Orgill, Robert D Galiano, Thomas E Serena, Marissa J Carter, Jarrod P Kaufman, Nathan J Young, Charles M Zelen
BACKGROUND: In a recently published, prospective randomized controlled trial (RCT) comparing aseptically processed dehydrated human amnion/chorion allograft (dHACA) to standard of care (SOC), 85% wound closure rates were reported in the dHACA arm while only 25% of patients in the SOC arm healed. OBJECTIVE: The purpose of this retrospective crossover study is to evaluate the effectiveness of dHACA in those patients that failed to respond to the SOC treatments and who exited the original study after failing up to 12 weeks of SOC treatment...
July 26, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28870096/major-health-service-transformation-and-the-public-voice-conflict-challenge-or-complicity
#13
Graham P Martin, Pam Carter, Mike Dent
Objectives Calls for major reconfigurations of health services have been accompanied by recommendations that wide ranging stakeholders be involved. In particular, patients and the wider public are seen as critical contributors as both funders and beneficiaries of public health care. But public involvement is fraught with challenges, and little research has focused on involvement in the health service transformation initiatives. This paper examines the design and function of public involvement in reconfiguration of health services within the English NHS...
January 1, 2017: Journal of Health Services Research & Policy
https://www.readbyqxmd.com/read/28869627/somatotype-variables-related-to-strength-and-power-output-in-male-basketball-players
#14
Krzysztof Buśko, Anna Pastuszak, Monika Lipińska, Marta Lipińska, Karol Gryko
PURPOSE: The purpose of this study was to investigate the relationship between somatotype, muscular strength, power output measured in maximal cycle ergometer exercise bouts, and maximal power output and height of rise of the body mass centre (jump height) measured in akimbo counter movement jump (ACMJ), counter movement jump (CMJ) and spike jump (SPJ), in male basketball players. METHODS: Thirteen male basketball players (second division, age 19.4 ± 0.8 years, body height 192...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/28866350/critical-thinking-evaluation-in-reflective-writing-development-and-testing-of-carter-assessment-of-critical-thinking-in-midwifery-reflection
#15
Amanda G Carter, Debra K Creedy, Mary Sidebotham
OBJECTIVE: develop and test a tool designed for use by academics to evaluate pre-registration midwifery students' critical thinking skills in reflective writing. DESIGN: a descriptive cohort design was used. SAMPLE: a random sample (n = 100) of archived student reflective writings based on a clinical event or experience during 2014 and 2015. METHODS: a staged model for tool development was used to develop a fifteen item scale involving item generation; mapping of draft items to critical thinking concepts and expert review to test content validity; inter-rater reliability testing; pilot testing of the tool on 100 reflective writings; and psychometric testing...
November 2017: Midwifery
https://www.readbyqxmd.com/read/28862935/what-is-the-relationship-between-dairy-intake-and-blood-pressure-in-black-and-white-children-and-adolescents-enrolled-in-a-weight-management-program
#16
Diane M DellaValle, Janet Carter, Molly Jones, Melissa Howard Henshaw
BACKGROUND: The DASH (Dietary Approaches to Stop Hypertension) clinical trials and other studies have demonstrated a relationship between diet and cardiovascular outcomes in adults, yet little is known of this relationship in children. Childhood obesity has reached epidemic proportions in the United States, with similar increases in hypertension among this population. The purpose of our study was to examine the association between dairy intake and blood pressure (BP) in a cohort of children and adolescents (aged 4-17 years) enrolled in a weight management program...
August 14, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28861367/safety-of-same-day-thyroidectomy-meta-analysis-and-systematic-review
#17
Helmi Khadra, Salah Mohamed, Adam Hauch, John Carter, Tian Hu, Emad Kandil
BACKGROUND: Performance of thyroid surgery as a same day surgery procedure has been a controversial topic. This study aimed to compare the safety and efficacy of outpatient thyroid surgery with inpatient thyroid surgery by meta-analysis of current literature. METHODS: Articles were identified from the following keyword searches: outpatient thyroidectomy/thyroid surgery, same day thyroidectomy/thyroid surgery. Outcomes included perioperative complications including recurrent laryngeal nerve (RLN) injury, hypocalcemia, and readmissions...
August 2017: Gland Surgery
https://www.readbyqxmd.com/read/28855173/sirukumab-for-rheumatoid-arthritis-the-phase-iii-sirround-d-study
#18
Tsutomu Takeuchi, Carter Thorne, George Karpouzas, Shihong Sheng, Weichun Xu, Ravi Rao, Kaiyin Fei, Benjamin Hsu, Paul P Tak
OBJECTIVES: Interleukin-6 (IL-6) is implicated in rheumatoid arthritis (RA) pathophysiology. Unlike IL-6 receptor inhibitors, sirukumab is a human monoclonal antibody that selectively binds to the IL-6 cytokine. The phase III, multicentre, randomised, double-blind, placebo-controlled, parallel-group SIRROUND-D study (ClinicalTrials.gov identifier NCT01604343) evaluated the efficacy and safety of sirukumab in patients with active RA refractory to disease-modifying antirheumatic drugs. METHODS: Patients were randomised 1:1:1 to treatment with sirukumab 100 mg every 2 weeks, 50 mg every 4 weeks or placebo every 2 weeks subcutaneously...
August 30, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28854673/peculiar-citric-acid-cycle-of-hydrothermal-vent-chemolithoautotroph-hydrogenovibrio-crunogenus-and-insights-into-carbon-metabolism-by-obligate-autotrophs
#19
Ishtiaque Quasem, Alexandra N Achille, Brittany A Caddick, Travis A Carter, Camille Daniels, Jennifer A Delaney, Vedad Delic, Kimberly A Denton, Martina C Duran, Marianne K Fatica, Christopher M Ference, Julie P Galkiewicz, Ana M Garcia, Jacqueline D Hendrick, Steven A Horton, Mey S Kun, Phoebe W Koch, Tien Min Lee, Christie R McCabe, Sean McHale, Lauren D McDaniel, Damian M Menning, Kristy J Menning, Hamed Mirzaei-Souderjani, Salina Mostajabian, David A Nicholson, Courtney K Nugent, Nicholas P Osman, Desiree I Pappas, Andrea M Rocha, Karyna Rosario, Haydn Rubelmann, Julie A Schwartz, Kent W Seeley, Christopher M Staley, Elizabeth M Wallace, Terianne M Wong, Brian L Zielinski, Thomas E Hanson, Kathleen M Scott
The genome sequence of the obligate chemolithoautotroph Hydrogenovibrio crunogenus paradoxically predicts a complete oxidative citric acid cycle (CAC). This prediction was tested by multiple approaches including whole cell carbon assimilation to verify obligate autotrophy, phylogenetic analysis of CAC enzyme sequences and enzyme assays. Hydrogenovibrio crunogenus did not assimilate any of the organic compounds provided (acetate, succinate, glucose, yeast extract, tryptone). Enzyme activities confirmed that its CAC is mostly uncoupled from the NADH pool...
August 1, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28843687/short-communication-sensitive-detection-of-norbixin-in-dried-dairy-ingredients-at-concentrations-of-less-than-1-part-per-billion
#20
B G Carter, C W Park, M A Drake
Norbixin is the water-soluble carotenoid in annatto extracts used in the cheese industry to color Cheddar cheese. The purpose of norbixin is to provide cheese color, but norbixin is also present in the whey stream and contaminates dried dairy ingredients. Regulatory restrictions dictate that norbixin cannot be present in dairy ingredients destined for infant formula or ingredients entering different international markets. Thus, there is a need for the detection and quantification of norbixin at very low levels in dried dairy ingredients to confirm its absence...
August 23, 2017: Journal of Dairy Science
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