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Francis D

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https://www.readbyqxmd.com/read/29331056/exploring-the-advantages-of-multiband-fmri-with-simultaneous-eeg-to-investigate-coupling-between-gamma-frequency-neural-activity-and-the-bold-response-in-humans
#1
Makoto Uji, Ross Wilson, Susan T Francis, Karen J Mullinger, Stephen D Mayhew
We established an optimal combination of EEG recording during sparse multiband (MB) fMRI that preserves high-resolution, whole-brain fMRI coverage while enabling broad-band EEG recordings which are uncorrupted by MRI gradient artefacts (GAs). We first determined the safety of simultaneous EEG recording during MB fMRI. Application of MB factor = 4 produced <1°C peak heating of electrode/hardware during 20 min of GE-EPI data acquisition. However, higher SAR sequences require specific safety testing, with greater heating observed using PCASL with MB factor = 4...
January 13, 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29330117/rifm-fragrance-ingredient-safety-assessment-phenethyl-isovalerate-cas-registry-number-140-26-1
#2
A M Api, D Belsito, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, M L Dagli, M Date, W Dekant, C Deodhar, M Francis, A D Fryer, K Joshi, S La Cava, A Lapczynski, D C Liebler, D O'Brien, R Parakhia, A Patel, T M Penning, G Ritacco, J Romine, D Salvito, T W Schultz, I G Sipes, Y Thakkar, E H Theophilus, A K Tiethof, Y Tokura, S Tsang, J Wahler
No abstract text is available yet for this article.
January 9, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29329187/deceased-donor-organ-transplantation-performed-in-the-united-states-for-non-citizens-and-non-residents
#3
Francis L Delmonico, Susan Gunderson, Kishore R Iyer, Gabriel M Danovitch, Timothy L Pruett, Jorge D Reyes, Nancy L Ascher
Since 2012, the Organ Procurement and Transplantation Network (OPTN)/United Network for Organ Sharing (UNOS) has required transplant centers to record the citizenship and residency status of patients undergoing transplantation in the United States. This policy replaced the 5% threshold of the non-US citizen/non-U.S. residents (NC/NR) undergoing organ transplantation that could result in an audit of transplant center activity.We analyzed the frequency of NC/NR deceased donor organ transplants and wait list registrations at all US transplant centers using data provided by UNOS for that purpose to the UNOS Ad Hoc International Relations Committee...
January 11, 2018: Transplantation
https://www.readbyqxmd.com/read/29327847/the-role-of-science-in-the-opioid-crisis
#4
Nora D Volkow, Francis S Collins
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29325807/rifm-fragrance-ingredient-safety-assessment-dodecanenitrile-cas-registry-number-2437-25-4
#5
A M Api, D Belsito, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, M L Dagli, M Date, W Dekant, C Deodhar, M Francis, A D Fryer, K Joshi, S La Cava, A Lapczynski, D C Liebler, D O'brien, R Parakhia, A Patel, T M Penning, G Ritacco, J Romine, D Salvito, T W Schultz, I G Sipes, Y Thakkar, E H Theophilus, A K Tiethof, Y Tokura, S Tsang, J Wahler
No abstract text is available yet for this article.
January 8, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29325806/rifm-fragrance-ingredient-safety-assessment-pentanedioic-acid-1-5-dimethyl-ester-cas-registry-number-1119-40-0
#6
A M Api, D Belsito, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, M L Dagli, M Date, W Dekant, C Deodhar, M Francis, A D Fryer, K Joshi, S La Cava, A Lapczynski, D C Liebler, D O'Brien, R Parakhia, A Patel, T M Penning, G Ritacco, J Romine, D Salvito, T W Schultz, I G Sipes, Y Thakkar, E H Theophilus, A K Tiethof, Y Tokura, S Tsang, J Wahler
No abstract text is available yet for this article.
January 8, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29324997/skin-lighteners-and-hair-relaxers-as-risk-factors-for-breast-cancer-results-from-the-ghana-breast-health-study
#7
Louise A Brinton, Jonine D Figueroa, Daniel Ansong, Kofi M Nyarko, Seth Wiafe, Joel Yarney, Richard Biritwum, Michelle Brotzman, Jake E Thistle, Ernest Adjei, Francis Aitpillah, Florence Dedey, Lawrence Edusei, Nicholas Titiloye, Baffour Awuah, Joe Nat Clegg-Lamptey, Beatrice Wiafe-Addai, Verna Vanderpuye
Skin lighteners and hair relaxers, both common among women of African descent, have been suggested as possibly affecting breast cancer risk. In Accra and Kumasi, Ghana, we collected detailed information on usage patterns of both exposures among 1,131 invasive breast cancer cases and 2,106 population-controls. Multivariate analyses estimated odds ratios (OR) and 95% confidence intervals (CIs) after adjustment for breast cancer risk factors. Control usage was 25.8% for ever use of skin lighteners and 90.0% for use of hair relaxers for >1 year...
January 6, 2018: Carcinogenesis
https://www.readbyqxmd.com/read/29320856/second-order-raman-scattering-in-exfoliated-black-phosphorus
#8
Alexandre Favron, Félix Antoine Goudreault, Vincent Gosselin, Julien Groulx, Michel Côté, Richard Leonelli, Jean-Francis Germain, Anne-Laurence Phaneuf-L'Heureux, Sébastien Francoeur, Richard Martel
Second-order Raman scattering has been extensively studied in carbon-based nanomaterials, \emph{e.g.} nanotube and graphene, because it activates normally forbidden Raman modes that are sensitive to crystal disorder, such as defects, dopants, strain, etc. The sp2-hybridized carbon systems are, however, the exception among most nanomaterials, where first-order Raman processes usually dominate. Here we report the identification of four second-order Raman modes, named D1, D'1, D2 and D'2, in exfoliated black phosphorus (P(black)), an elemental direct-gap semiconductor exhibiting strong mechanical and electronic anisotropies...
January 10, 2018: Nano Letters
https://www.readbyqxmd.com/read/29319620/liver-transplantation-for-nash-related-hepatocellular-carcinoma-versus-non-nash-etiologies-of-hepatocellular-carcinoma
#9
Erin M Sadler, Neil Mehta, Mamatha Bhat, Anand Ghanekar, Paul D Greig, David R Grant, Francis Yao, Gonzalo Sapisochin
BACKGROUND: Liver Transplant (LT) for Non-Alcoholic Steatohepatitis (NASH) related Hepatocellular Carcinoma (HCC) is not well characterized in the literature. The aim of the study was to examine characteristics and outcomes of patients who had LT for NASH-HCC (NASH) vs. HCC from other liver diseases (non-NASH). METHODS: Using a two-centre retrospective design all patients from 2004-2014 that received LT for HCC were analyzed. Subgroup analysis stratified patients according to Milan criteria...
January 10, 2018: Transplantation
https://www.readbyqxmd.com/read/29317331/rifm-fragrance-ingredient-safety-assessment-benzyl-formate-cas-registry-number-104-57-4
#10
A M Api, D Belsito, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, M L Dagli, M Date, W Dekant, C Deodhar, M Francis, A D Fryer, K Joshi, S L A Cava, A Lapczynski, D C Liebler, D O'Brien, R Parakhia, A Patel, T M Penning, G Ritacco, J Romine, D Salvito, T W Schultz, I G Sipes, Y Thakkar, E H Theophilus, A K Tiethof, Y Tokura, S Tsang, J Wahler
No abstract text is available yet for this article.
January 6, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29317329/rifm-fragrance-ingredient-safety-assessment-5-8-methano-2h-1-benzopyran-2-one-6-ethylideneoctahydro-cas-registry-number-69486-14-2
#11
A M Api, D Belsito, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, M L Dagli, M Date, W Dekant, C Deodhar, M Francis, A D Fryer, K Joshi, S La Cava, A Lapczynski, D C Liebler, D O'Brien, R Parakhia, A Patel, T M Penning, G Ritacco, J Romine, D Salvito, T W Schultz, I G Sipes, Y Thakkar, E H Theophilus, A K Tiethof, Y Tokura, S Tsang, J Wahler
No abstract text is available yet for this article.
January 6, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29316017/a-comparison-of-graft-and-patient-outcomes-following-kidney-transplantation-in-extended-hour-and-conventional-haemodialysis-patients
#12
Emily J See, Carmel M Hawley, Yeoungjee Cho, Nigel D Toussaint, John Wm Agar, Elaine M Pascoe, Wai H Lim, Ross S Francis, Michael G Collins, David W Johnson
AIM: Differences in early graft function between kidney transplant recipients previously managed with either haemodialysis (HD) or peritoneal dialysis are well described. However, only two single-centre studies have compared graft and patient outcomes between extended hour and conventional HD patients, with conflicting results. METHODS: This study compared the outcomes of all extended hour (≥24 hours/week) and conventional HD patients transplanted in Australia and New Zealand between 2000 and 2014...
January 8, 2018: Nephrology
https://www.readbyqxmd.com/read/29315638/comparative-genomics-and-transcriptomics-depict-ericoid-mycorrhizal-fungi-as-versatile-saprotrophs-and-plant-mutualists
#13
Elena Martino, Emmanuelle Morin, Gwen-Aëlle Grelet, Alan Kuo, Annegret Kohler, Stefania Daghino, Kerrie W Barry, Nicolas Cichocki, Alicia Clum, Rhyan B Dockter, Matthieu Hainaut, Rita C Kuo, Kurt LaButti, Björn D Lindahl, Erika A Lindquist, Anna Lipzen, Hassine-Radhouane Khouja, Jon Magnuson, Claude Murat, Robin A Ohm, Steven W Singer, Joseph W Spatafora, Mei Wang, Claire Veneault-Fourrey, Bernard Henrissat, Igor V Grigoriev, Francis M Martin, Silvia Perotto
Some soil fungi in the Leotiomycetes form ericoid mycorrhizal (ERM) symbioses with Ericaceae. In the harsh habitats in which they occur, ERM plant survival relies on nutrient mobilization from soil organic matter (SOM) by their fungal partners. The characterization of the fungal genetic machinery underpinning both the symbiotic lifestyle and SOM degradation is needed to understand ERM symbiosis functioning and evolution, and its impact on soil carbon (C) turnover. We sequenced the genomes of the ERM fungi Meliniomyces bicolor, M...
January 7, 2018: New Phytologist
https://www.readbyqxmd.com/read/29311304/chronic-anthropogenic-noise-disrupts-glucocorticoid-signaling-and-has-multiple-effects-on-fitness-in-an-avian-community
#14
Nathan J Kleist, Robert P Guralnick, Alexander Cruz, Christopher A Lowry, Clinton D Francis
Anthropogenic noise is a pervasive pollutant that decreases environmental quality by disrupting a suite of behaviors vital to perception and communication. However, even within populations of noise-sensitive species, individuals still select breeding sites located within areas exposed to high noise levels, with largely unknown physiological and fitness consequences. We use a study system in the natural gas fields of northern New Mexico to test the prediction that exposure to noise causes glucocorticoid-signaling dysfunction and decreases fitness in a community of secondary cavity-nesting birds...
January 8, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29310555/mechanical-circulatory-support-for-the-failing-fontan-conversion-to-assisted-single-ventricle-circulation-preliminary-observations
#15
Syed M Peer, Kristopher B Deatrick, Thomas J Johnson, Jonathan W Haft, Francis D Pagani, Richard G Ohye, Edward L Bove, Alvaro Rojas-Peña, Ming-Sing Si
BACKGROUND: Mechanical circulatory support (MCS) of a failing Fontan circulation remains challenging. We hypothesized that MCS can be provided by converting the Fontan circulation into a mechanically assisted single ventricle parallel circulation (MASVC). METHODS: A porcine model of functionally univentricular circulation was created under cardiopulmonary bypass (CPB) by performing an atrial septectomy, tricuspid valvectomy, and interrupting antegrade pulmonary blood flow...
January 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29305930/rifm-fragrance-ingredient-safety-assessment-phenethyl-tiglate-cas-registry-number-55719-85-2
#16
A M Api, D Belsito, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, M L Dagli, M Date, W Dekant, C Deodhar, M Francis, A D Fryer, K Joshi, S La Cava, A Lapczynski, D C Liebler, D O'brien, R Parakhia, A Patel, T M Penning, G Ritacco, J Romine, D Salvito, T W Schultz, I G Sipes, Y Thakkar, E H Theophilus, A K Tiethof, Y Tokura, S Tsang, J Wahler
No abstract text is available yet for this article.
January 3, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29305348/computed-tomographic-coronary-angiography-derived-plaque-characteristics-predict-major-adverse-cardiovascular-events-a-systematic-review-and-meta-analysis
#17
Nitesh Nerlekar, Francis J Ha, Caitlin Cheshire, Hashrul Rashid, James D Cameron, Dennis T Wong, Sujith Seneviratne, Adam J Brown
BACKGROUND: Computed tomographic coronary angiography is a noninvasive imaging modality that permits identification and characterization of coronary plaques. Despite consensus statements supporting routine reporting of computed tomographic coronary angiography plaque characteristics, there remains uncertainty whether these data convey prognostic information. We performed a systematic review and meta-analysis assessing the strength of association between computed tomographic coronary angiography-derived plaque characterization and major adverse cardiovascular events (MACE)...
January 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29305031/early-postoperative-hemodynamic-monitoring-in-patients-with-a-left-ventricular-assist-device-more-than-just-numbers
#18
EDITORIAL
Francis D Pagani
No abstract text is available yet for this article.
November 7, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29301825/genomic-correlates-of-response-to-everolimus-in-aggressive-radioiodine-refractory-thyroid-cancer-a-phase-ii-study
#19
Glenn J Hanna, Naifa L Busaidy, Nicole G Chau, Lori J Wirth, Justine A Barletta, Antonio Calles, Robert I Haddad, Stefan Kraft, Maria E Cabanillas, Guilherme Rabinowits, Anne O'Neill, Sewanti A Limaye, Erik K Alexander, Francis D Moore, Krzysztof Misiukiewicz, Tom Thomas, Matthew A Nehs, Ellen Marqusee, Stephanie L Lee, Pasi A Janne, Jochen H Lorch
PURPOSE: Targeting mutations leading to PI3K/mTOR/Akt activation are of interest in thyroid cancer (TC). We evaluated the efficacy of everolimus in aggressive, radioactive iodine refractory (RAIR) TC and correlated tumor mutational profiling with response. Exploratory medullary and anaplastic TC cohorts were included. EXPERIMENTAL DESIGN: This single-arm, multi-institutional phase II study was conducted from 2009-2013 in patients with incurable RAIR TC who had radiographic progression six months prior to enrollment...
January 4, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29301747/an-rna-based-digital-circulating-tumor-cell-signature-is-predictive-of-drug-response-and-early-dissemination-in-prostate-cancer
#20
David T Miyamoto, Richard J Lee, Mark Kalinich, Joseph LiCausi, Yu Zheng, Tianqi Chen, John D Milner, Erin Emmons, Uyen Ho, Katherine Broderick, Erin Silva, Sarah Javaid, Tanya Todorova Kwan, Xin Hong, Douglas M Dahl, Francis J McGovern, Jason A Efstathiou, Matthew R Smith, Lecia V Sequist, Ravi Kapur, Chin-Lee Wu, Shannon L Stott, David T Ting, Anita Giobbie-Hurder, Mehmet Toner, Shyamala Maheswaran, Daniel A Haber
Blood-based biomarkers are critical in metastatic prostate cancer, where characteristic bone metastases are not readily sampled, and they may enable risk stratification in localized disease. We established a sensitive and high-throughput strategy for analyzing prostate circulating tumor cells (CTCs) using microfluidic cell enrichment followed by digital quantitation of prostate-derived transcripts. In a prospective study of 27 metastatic castration-resistant prostate cancer patients treated with first-line abiraterone, pretreatment elevation of the digital CTCM Score identifies a high risk population with poor overall survival (HR 6...
January 4, 2018: Cancer Discovery
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