D A Healy, W A Khan, C S Wong, M Clarke Moloney, P A Grace, J C Coffey, C Dunne, S R Walsh, U Sadat, M E Gaunt, S Chen, S Tehrani, D J Hausenloy, D M Yellon, R S Kramer, R F Zimmerman, V V Lomivorotov, V A Shmyrev, D N Ponomarev, I A Rahman, J G Mascaro, R S Bonser, Y Jeon, D M Hong, R Wagner, M Thielmann, G Heusch, K Zacharowski, P Meybohm, B Bein, T Y Tang
BACKGROUND: A number of 'proof-of-concept' trials suggest that remote ischaemic preconditioning (RIPC) reduces surrogate markers of end-organ injury in patients undergoing major cardiovascular surgery. To date, few studies have involved hard clinical outcomes as primary end-points. METHODS: Randomised clinical trials of RIPC in major adult cardiovascular surgery were identified by a systematic review of electronic abstract databases, conference proceedings and article reference lists...
September 2014: International Journal of Cardiology