Suzana Tanni, Fernando Wehrmeister, Robson Prudente, Felipe Damatto, Carlos Breda Neto, Leiliane Oliveira, Luana Pagan, Mariana Gatto, Letícia Vieira, Liana Coelho, Diane Rezende, Luiz Machado, Gustavo Mota, Marina Gaiato, Felipe Santaella, Elisângela Campos, Estefânia Franco, Matheus Callegari, Marina Politi Okoshi, Ulla Weinreich
(1) Background: A high concentration of sodium chloride on in vitro cell culture leads to reduced SARS-CoV-2 replication. Therefore, our aim was to evaluate the effects of inhaling hypertonic NaCl particles (BREATHOX® ) on the duration of COVID-19-induced acute symptoms. (2) Methods: A prospective, open label, randomized, standard of care-controlled group (SOC) pilot trial compared inhaled oral and nasal administered BREATHOX® (2.0 mg NaCl, particles size between 1-10 μm), with five or ten inhalations per day for ten days...
September 20, 2023: Journal of Clinical Medicine