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sensitivity tests functional lobectomy

Bram-Ernst Verhoef, Thomas Decramer, Johannes van Loon, Jan Goffin, Wim Van Paesschen, Peter Janssen, Tom Theys
Brain areas critical for stereopsis have been investigated in non-human primates but are largely unknown in the human brain. Microelectrode recordings and functional MRI (fMRI) studies in monkeys have shown that in monkeys the inferior temporal cortex is critically involved in 3D shape categorization. Furthermore, some human fMRI studies similarly suggest an involvement of visual areas in the temporal lobe in depth perception. We aimed to investigate the role of the human anterior temporal neocortex in stereopsis by assessing stereoscopic depth perception before and after anterior temporal lobectomy...
September 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Olivier Boucher, Emmanuelle Dagenais, Alain Bouthillier, Dang Khoa Nguyen, Isabelle Rouleau
The advantage of selective amygdalohippocampectomy (SAH) over anterior temporal lobectomy (ATL) for the treatment of temporal lobe epilepsy (TLE) remains controversial. Because ATL is more extensive and involves the lateral and medial parts of the temporal lobe, it may be predicted that its impact on memory is more important than SAH, which involves resection of medial temporal structures only. However, several studies do not support this assumption. Possible explanations include task-specific factors such as the extent of semantic and syntactic information to be memorized and failure to control for main confounders...
November 2015: Epilepsy & Behavior: E&B
Tevfik Kaplan, Gokce Kaan Atac, Nesimi Gunal, Bulent Kocer, Aslıhan Alhan, Sezai Cubuk, Orhan Yucel, Ebru Ozan Sanhal, Koray Dural, Serdar Han
BACKGROUND: The aim of this study was to evaluate the pulmonary reserve of the patients via preoperative quantitative computerized tomography (CT) and to determine if these preoperative quantitative measurements could predict the postoperative pulmonary morbidity. METHODS: Fifty patients with lung cancer who underwent lobectomy/segmentectomy were included in the study. Preoperative quantitative CT scans and pulmonary function tests data were evaluated retrospectively...
August 2015: Journal of Thoracic Disease
Christopher P Fagundes, Qiuling Shi, Ara A Vaporciyan, David C Rice, Keyuri U Popat, Charles S Cleeland, Xin Shelley Wang
OBJECTIVES: Measuring patient-reported outcomes (PROs) has become increasingly important for assessing quality of care and guiding patient management. However, PROs have yet to be integrated with traditional clinical outcomes (such as length of hospital stay), to evaluate perioperative care. This study aimed to use longitudinal PRO assessments to define the postoperative symptom recovery trajectory in patients undergoing thoracic surgery for lung cancer. METHODS: Newly diagnosed patients (N = 60) with stage I or II non-small cell lung cancer who underwent either standard open thoracotomy or video-assisted thoracoscopic surgery lobectomy reported multiple symptoms from before surgery to 3 months after surgery, using the MD Anderson Symptom Inventory...
September 2015: Journal of Thoracic and Cardiovascular Surgery
Meneka K Sidhu, Jason Stretton, Gavin P Winston, Mark Symms, Pamela J Thompson, Matthias J Koepp, John S Duncan
OBJECTIVE: To develop a clinically applicable memory functional MRI (fMRI) method of predicting postsurgical memory outcome in individual patients. METHODS: In this prospective cohort study, 50 patients with temporal lobe epilepsy (23 left) and 26 controls underwent an fMRI memory encoding paradigm of words with a subsequent out-of-scanner recognition assessment. Neuropsychological assessment was performed preoperatively and 4 months after anterior temporal lobe resection, and at equal time intervals in controls...
April 14, 2015: Neurology
Kwon Joong Na, Chang Hyun Kang, Jae Hyun Jeon, Yong Won Seong, In Kyu Park, Jin Mo Goo, Young Tae Kim
OBJECTIVE: To determine whether the percentile quantification of emphysema with computed tomography has a stronger association with pulmonary complications than pulmonary function testing after pulmonary lobectomy. METHODS: The patients who underwent pulmonary lobectomy and also had thin-section chest computed tomography scans available from July 2009 through August 2011 were reviewed. The patients were divided into 2 groups according to whether they had a history of chronic obstructive pulmonary disease...
March 2014: Journal of Thoracic and Cardiovascular Surgery
Xiaoyu Yang, Aijun Li, Mengchao Wu
The aim of the study was to review the main clinical, imaging and pathological features of hepatic angiomyolipoma (HAML). We retrospectively analyzed the imaging, pathological and clinical features of 178 patients who underwent surgical resection for HAML. Forty-three males and 135 females with a median age of 43.5 years (range: 17-76 years) were enrolled in the study. Routine blood tests, including those for α-fetoprotein, carcinoembryonic antigen, and carbohydrate antigen determinant, were normal. Liver function was classified as Child-Pugh A for all patients...
March 2013: Medical Oncology
Aimen Kasasbeh, Edward C Hwang, Karen Steger-May, S Kathleen Bandt, Amy Oberhelman, David Limbrick, Michelle M Miller-Thomas, Joshua S Shimony, Matthew D Smyth
OBJECT: Mesial temporal sclerosis (MTS) is widely recognized as a significant underlying cause of temporal lobe epilepsy. Magnetic resonance imaging is routinely used in the preoperative evaluation of children with epilepsy. The purpose of this study was to evaluate the prevalence, reliability, and prognostic value of MRI identification of MTS and MRI findings indicative of MTS in a series of patients who underwent resection of the medial temporal lobe for medically refractory epilepsy...
May 2012: Journal of Neurosurgery. Pediatrics
Silvia B Bonelli, Pamela J Thompson, Mahinda Yogarajah, Christian Vollmar, Robert H W Powell, Mark R Symms, Andrew W McEvoy, Caroline Micallef, Matthias J Koepp, John S Duncan
PURPOSE: Anterior temporal lobe resection (ATLR) controls seizures in up to 70% of patients with intractable temporal lobe epilepsy (TLE) but, in the language dominant hemisphere, may impair language function, particularly naming. Functional reorganization can occur within the ipsilateral and contralateral hemispheres. We investigated reorganization of language in left-hemisphere-dominant patients before and after ATLR; whether preoperative functional magnetic resonance imaging (fMRI) predicts postoperative naming decline; and efficiency of postoperative language networks...
April 2012: Epilepsia
F Irsel Tezer, Nese Dericioglu, Gokhan Bozkurt, Burcak Bilginer, Nejat Akalan, Serap Saygi
AIM: Concordance of EEG findings and MRI is best correlated with favored surgical outcome in patients with unilateral mesial temporal sclerosis (MTS). If there is no evidence for unilateral focus with scalp EEG, invasive recordings are undertaken. In this report we describe the investigation process for epilepsy surgery in patients with unilateral MTS and contralateral ictal scalp EEG findings. MATERIAL AND METHODS: The data of all adult patients who had undergone videoEEG recording with subdural and/or depth electrodes at our center in almost 7...
2011: Turkish Neurosurgery
K Wildgaard, T K Ringsted, H J Hansen, R H Petersen, M U Werner, H Kehlet
BACKGROUND: Video-assisted thoracic surgery (VATS) lobectomy may potentially reduce the risk of post-thoracotomy pain syndrome (PTPS). However, it may still carry a risk of intraoperative nerve damage and thereby development of PTPS. Thus, our aim was to present a detailed long-term neurophysiological characterization of PTPS after VATS. METHODS: Quantitative sensory testing, using thermal and mechanical stimuli, was performed in 13 PTPS patients and 35 pain-free patients recruited 33 months after VATS lobectomy...
January 2012: British Journal of Anaesthesia
Amin Sabet, Johanna A Pallotta
BACKGROUND: Resistance to thyroid hormone (RTH) is a rare syndrome of reduced TH sensitivity most often due to mutations affecting the β-isoform of the thyroid hormone receptor (TRβ). Patients with RTH may develop hypothyroidism as a result of surgery, mistreatment with radioiodine, or autoimmune thyroid disease. PATIENT FINDINGS: We describe a patient who underwent partial thyroid lobectomy for benign goiter at age 17 and remained healthy through five uncomplicated pregnancies before abnormal laboratory results were noted...
May 2011: Thyroid: Official Journal of the American Thyroid Association
Qi Li, Min Cao, Guohong Zhang, Guixin Sun, Botao Dong, Hongyun Ruan, Zhiru Wang
BACKGROUND: To evaluate the clinical significance of predicting post-operative respiratory failure in patients with lung cancer using cardiopulmonary exercise test (CPET). METHODS: Before operation, 260 patients with lung cancer underwent CPET with incremental protocol. W%, VO₂%P, VO₂/kg, AT, MET, O₂ pulse, VTe, BF and VE were measured in the end of load exercise. RESULTS: (1) In patients after pneumonectomy, the values of the above indexes of CPET in the respiratory failure group were significantly lower than those in the non-respiratory failure group ( P < 0...
October 20, 2003: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Soo Hwan Kim, Sungwon Na, Jin-Sub Choi, Se Hee Na, Seokyung Shin, Shin Ok Koh
BACKGROUND: Diaphragmatic dysfunction is a major factor in the etiology of postoperative pulmonary complications after upper abdominal surgery. M-mode ultrasonography is now an accepted qualitative method of assessing diaphragmatic motion in normal and pathological conditions. In this study, we evaluated whether diaphragmatic inspiratory amplitude (DIA) as measured by M-mode sonography can be a predictor of pulmonary dysfunction. METHODS: A prospective, single-center, single-unit, observational study was performed in 35 ASA physical status I and II nonsmoking patients undergoing open liver lobectomy...
May 1, 2010: Anesthesia and Analgesia
Kitti Kaiboriboon, Srikantan Nagarajan, Mary Mantle, Heidi E Kirsch
OBJECTIVE: To evaluate the ability of MEG to detect medial temporal spikes in patients with known medial temporal lobe epilepsy (MTLE) and to use magnetic source imaging (MSI) with equivalent current dipoles to examine localization and orientation of spikes and their relation to surgical outcome. METHODS: We prospectively obtained MSI on a total of 25 patients previously diagnosed with intractable MTLE. MEG was recorded with a 275 channel whole-head system with simultaneous 21-channel scalp EEG during inpatient admission one day prior to surgical resection...
March 2010: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
Thomas Bengner, Thomas Malina
There is a shortage of neuropsychological tests to assess right temporal lobe memory function in TLE patients. Although right temporal lobe dominance for face memory is well established, neuropsychological studies on face memory in epilepsy surgery candidates have reported mixed results. These latter studies in TLE patients mostly concentrated on immediate face recognition. There is evidence suggesting that increasing test delays raise the sensitivity of neuropsychological face recognition tests to predict face memory decline after right temporal lobectomy...
March 2010: Epilepsy Research
Christopher W Seder, Kenny Hanna, Victoria Lucia, Judith Boura, Sang W Kim, Robert J Welsh, Gary W Chmielewski
BACKGROUND: We hypothesized that established thoracic surgeons without formal minimally invasive training can learn thoracoscopic lobectomy without compromising patient safety or outcome. METHODS: Data were retrospectively collected on patients who underwent pulmonary lobectomy at a single health system between August 1, 2003, and April 1, 2008. Age, sex, pulmonary function tests, preoperative and postoperative stages, pathologic diagnosis, anatomic resection, extent of lymph node sampling, surgical technique and duration, complications, blood loss, transfusion requirement, chest tube duration, length of hospital stay, 30-day readmission, and mortality rate were examined...
July 2009: Annals of Thoracic Surgery
Kentaro Yoshimoto, Hiroaki Nomori, Takeshi Mori, Hironori Kobayashi, Yasuomi Ohba, Hidekatsu Shibata, Kuniyuki Tashiro, Shinya Shiraishi, Toshiaki Kobayashi
OBJECTIVE: The impact of segmentectomy for preservation of pulmonary function was quantified by using a co-registered perfusion single-photon-emission computed tomography and multidetector computed tomography (SPECT/CT). METHODS: Pulmonary function tests and perfusion SPECT/CT were conducted before and after segmentectomy in 56 patients. Actual values of forced expiratory volume in 1 second (FEV(1)) after segmentectomy were compared with the FEV(1) after virtual lobectomy, which was calculated by SPECT/CT...
May 2009: Journal of Thoracic and Cardiovascular Surgery
Jessica S Chapin, Robyn M Busch, Richard I Naugle, Imad M Najm
This study examined the extent to which the Family Pictures (FP) subtest of the Wechsler Memory Scale-Third Edition (WMS-III) is related to verbal memory measures and right mesial temporal integrity. Epilepsy patients who underwent temporal lobectomy did not differ in the extent to which FP scores changed from before to after surgery, although postoperative FP performance was worse in those who underwent right temporal lobectomy than in those who underwent left temporal lobectomy. FP was most strongly related to the Logical Memory subtest from the WMS-III...
May 2009: Journal of Clinical and Experimental Neuropsychology
Alessandro Brunelli, Majed Refai, Francesco Xiumé, Michele Salati, Valeria Sciarra, Laura Socci, Armando Sabbatini
BACKGROUND: Exercise tests are increasingly used during preoperative evaluation before lung resection. This study assessed the association between performance at the symptom-limited stair-climbing test and postoperative cardiopulmonary morbidity, mortality, and costs after major lung resections. METHODS: As part of their routine preoperative evaluation, 640 patients who had lobectomy (n = 533) or pneumonectomy (n = 107) for lung cancer from January 2000 through April 2007 performed a preoperative symptom-limited stair-climbing test...
July 2008: Annals of Thoracic Surgery
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