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https://www.readbyqxmd.com/read/29775980/-comparison-of-the-masaoka-koga-classification-with-the-new-tnm-staging-of-the-iaslc-itmig-for-thymoma-and-thymic-carcinoma
#1
Michael Ried, Maria-Magdalena Eicher, Reiner Neu, Dietmar Kraus, Sebastian Inderhees, Alexander Marx, Hans-Stefan Hofmann
BACKGROUND: The Masaoka-Koga classification describes the extent and spread of thymic epithelial malignancies. The objective of this study was to evaluate the Masaoka-Koga and the new TNM-staging system regarding differences in stage distributions, clinical implementation and therapeutic consequences. METHODS: Retrospective analysis of all patients who underwent surgery between January 2005 and December 2015 for thymoma/thymic carcinoma in two centres for thoracic surgery...
May 18, 2018: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29748435/end-of-treatment-and-serial-pet-imaging-in-primary-mediastinal-b-cell-lymphoma-following-dose-adjusted-epoch-r-a-paradigm-shift-in-clinical-decision-making
#2
Christopher Melani, Ranjana Advani, Mark Roschewski, Kelsey M Walters, Clara C Chen, Lucia Baratto, Mark A Ahlman, Milos D Miljkovic, Seth M Steinberg, Jessica Lam, Margaret Shovlin, Kieron Dunleavy, Stefania Pittaluga, Elaine S Jaffe, Wyndham H Wilson
Dose-adjusted-EPOCH-R obviates the need for radiotherapy in most patients with primary mediastinal B-cell lymphoma. End-of-treatment PET, however, does not accurately identify patients at risk of treatment failure, thereby confounding clinical decision making. To define the role of PET in primary mediastinal B-cell lymphoma following dose-adjusted-EPOCH-R, we extended enrollment and follow-up on our published phase II trial and independent series. Ninety-three patients received dose-adjusted-EPOCH-R without radiotherapy...
May 10, 2018: Haematologica
https://www.readbyqxmd.com/read/29739439/immature-teratoma-mimicking-pulmonary-stenosis-a-case-report
#3
Dardan Koçinaj, Xhevdet Krasniqi, Aurora Bakalli
BACKGROUND: Immature teratoma in a mediastinal location is a rare disease that might present as a valve pathology. Germ cell tumors with mediastinal locations account for up to 6% of immature teratoma cases. We present a case of an immature teratoma located primarily in the anterior mediastinum that manifested solely through symptoms of pulmonary stenosis. CASE PRESENTATION: We report a case of a 20-year-old white man with an immature teratoma who presented with progressive exertional dyspnea...
May 9, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29736699/performance-of-fdg-pet-ct-in-solitary-pulmonary-nodule-based-on-pre-test-likelihood-of-malignancy-results-from-the-italian-retrospective-multicenter-trial
#4
Laura Evangelista, Alberto Cuocolo, Leonardo Pace, Luigi Mansi, Silvana Del Vecchio, Paolo Miletto, Silvia Sanfilippo, Sara Pellegrino, Luca Guerra, Giovanna Pepe, Giuseppina Peluso, Marco Salvatore, Rosj Galicchio, Michele Zuffante, Salvatore Annunziata, Mohsen Farsad, Agostino Chiaravalloti, Marco Spadafora
PURPOSE: The aim of this study was to determine the performance of 18 F-FDG-PET/CT in patients with solitary pulmonary nodule (SPN), stratifying the risk according to the likelihood of pulmonary malignancy. METHODS: FDG-PET/CT of 502 patients, stratified for pre-test cancer risk, were retrospectively analyzed. FDG uptake in SPN was assessed by a 4-point scoring system and semiquantitative analysis using the ratio between SUVmax in SPN and SUVmean in mediastinal blood pool (BP) and between SUVmax in SPN and SUVmean in liver (L)...
May 7, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29674395/bilateral-tension-pneumothorax-after-acupuncture
#5
Nurashikin Mohammad
Acupuncture is an ancient complementary medicine which is currently used worldwide. Many serious adverse events have been reported which include a spectrum of mild-to-fatal complications. However, the level of awareness with regard to complications is still low both to physicians and patients. We report a 63-year-old who presented with acute shortness of breath 2 hours after having had acupuncture. On examination, there was absent breath sound heard on the left lung and slightly reduced breath sound on the right lung...
April 19, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29644288/massive-bilateral-chylothorax-post-blunt-trauma
#6
Christina Kozul, Karishma Jassal, Rodney Judson
Chylothorax caused by blunt trauma is extremely rare. We present a case of bilateral massive chylothorax post blunt trauma and a review of the literature regarding the identification and management of this rare diagnosis. An eighteen-year-old male was involved in a motor vehicle crash where he sustained multiple injuries including a right, moderate to large, haemopneumothorax, a small left haemopneumothorax, left T8, T9, L1 and L2 acute transverse process fractures and fractures of bilateral 11th ribs. An intercostal catheter was inserted on the right side which initially drained blood-stained fluid however milky colour fluid was noted to be draining 11 h post insertion...
December 2017: Trauma Case Reports
https://www.readbyqxmd.com/read/29600080/emergency-drain-for-post-pneumonectomy-bronchopleural-fistula-a-drain-placement-technique-based-on-the-siphon-principle
#7
Francesco Petrella, Alberto Sandri, Stefania Rizzo, Alessandro Borri, Domenico Galetta, Roberto Gasparri, Lorenzo Spaggiari
Post pneumonectomy bronchopleural fistula (BPF) is a life-threatening complication requiring pleural cavity drainage to avoid acute mediastinal shift and contralateral aspiration pneumonia. Chest drain insertion in this situation may be technically difficult because of drastic anatomical changes such as mediastinal dislocation, diaphragm elevation and, sometimes, massive subcutaneous emphysema. In addition, the most important part of the pleural cavity to be drained is the costophrenic recess that is scarcely drained by a standard chest tube with its tip aiming high and upwards...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29573050/mri-for-solitary-pulmonary-nodule-and-mass-assessment-current-state-of-the-art
#8
Yoshiharu Ohno, Hans-Ulrich Kauczor, Hiroto Hatabu, Joon Beom Seo, Edwin J R van Beek
Since the clinical introduction of magnetic resonance imaging (MRI), the chest has been one of its most challenging applications, and many physicists and radiologists have tried since the 1980s to use MR for assessment of different lung diseases as well as mediastinal and pleural diseases. Since then, however, technical advances in sequencing, scanners, and coils, adaptation of parallel imaging techniques, utilization of contrast media, and development of postprocessing tools have been reported by many basic and clinical researchers...
March 23, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29519239/usefulness-of-fetal-magnetic-resonance-imaging-for-postnatal-management-of-congenital-lung-cysts-prediction-of-probability-for-emergency-surgery
#9
Chiyoe Shirota, Takahisa Tainaka, Toshiki Nakane, Yujiro Tanaka, Akinari Hinoki, Wataru Sumida, Naruhiko Murase, Kazuo Oshima, Kosuke Chiba, Ryo Shirotsuki, Hiroo Uchida
BACKGROUND: Emergency rescue lung resection is rarely performed to treat congenital lung cysts (CLCs) in neonates. Many reports have described fetal CLC treatment; however, prenatal predictors for postnatal respiratory failure have not been characterized. We hypothesized that fetal imaging findings are useful predictors of emergency surgery. METHODS: We retrospectively studied patients with CLC who underwent lung surgery during the neonatal period in our hospital between January 2001 and December 2015...
March 8, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29479562/anatomical-and-radiological-considerations-when-colonic-perforation-leads-to-subcutaneous-emphysema-pneumothoraces-pneumomediastinum-and-mediastinal-shift
#10
REVIEW
Sala Abdalla, Rupinder Gill, Gibran Timothy Yusuf, Rosaria Scarpinata
While colonoscopy is generally regarded as a safe procedure, colonic perforation can occur and the risk of this is higher when interventional procedures are undertaken. The presentation may be acute or delayed depending on the extent of the perforation. Extracolonic gas following colonic perforation can migrate to several body compartments that are embryologically related and it has previously been reported in the thorax, mediastinum, neck, scrotum, and lower limbs. This review discusses in detail the anatomical pathways that led to a rare case of widespread subcutaneous emphysema, bilateral pneumothoraces, pneumomediastinum, and mediastinal shift from colonic perforation during a diagnostic colonoscopy...
January 2018: Surgery Journal
https://www.readbyqxmd.com/read/29430829/the-two-bridges-technique-for-sternal-wound-closure-the-use-of-vacuum-assisted-closure-for-the-treatment-of-deep-sternal-wound-defects-a-centre-specific-technique
#11
Karl Waked, Philippe Ballaux, Dominique Goossens, Koen Cathenis
The objective is to describe the 'Two Bridges Technique' (TBT), which has proven to be successful and has been the standard technique at our centre for vacuum-assisted closure (VAC) of post-sternotomy mediastinitis. An extensive literature search was performed in four databases to identify all published articles concerning VAC for post-sternotomy mediastinitis. Several VAC methods have been used; however, no article has described our specific technique. TBT consists of a two-bridges construction using two types of foam with different pore sizes, which ensures an equally divided negative pressure over the wound bed and stabilisation of the chest...
April 2018: International Wound Journal
https://www.readbyqxmd.com/read/29372563/cladosporium-cladosporioides-complex-infection-in-a-mixed-breed-dog
#12
Matteo Spano, Davide Zuliani, Andrea Peano, Walter Bertazzolo
A 3-year-old female mixed-breed dog was referred with a 2-day history of serious dyspnea, coughing, lethargy, anorexia, and a low-grade right anterior lameness. At presentation, the dog had an increased respiratory rate, dull heart and lung sounds, and cyanotic mucous membranes. It was hyperthermic and slightly dehydrated. Laboratory findings showed mild neutrophilia with a left shift, while serum biochemistry variables were in the normal range. However, urinalysis revealed mild proteinuria and rare erythrocytes and leukocytes on sediment examination...
March 2018: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/29258694/systematic-intrafraction-shifts-of-mediastinal-lymph-node-targets-between-setup-imaging-and-radiation-treatment-delivery-in-lung-cancer-patients
#13
Mai Lykkegaard Schmidt, Lone Hoffmann, Ditte S Møller, Marianne Marquard Knap, Torben Riis Rasmussen, Birgitte Holst Folkersen, Per Rugaard Poulsen
BACKGROUND AND PURPOSE: Internal target motion results in geometrical uncertainties in lung cancer radiotherapy. In this study, we determined the intrafraction motion and baseline shifts of mediastinal lymph node (LN) targets between setup imaging and treatment delivery. MATERIAL AND METHODS: Ten lung cancer patients with 2-4 fiducial markers implanted in LN targets received intensity-modulated radiotherapy with a daily setup cone-beam CT (CBCT) scan used for online soft-tissue match on the primary tumor...
February 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29207814/congenital-lobar-emphysema-anaesthetic-challenges-and-review-of-literature
#14
Suman Saini, Smita Prakash, Meera Rajeev, K K Girdhar
Congenital Lobar Emphysema (CLE) is a developmental anomaly, characterized by hyperinflation of one or more pulmonary lobes. It presents in infancy with variable degree of respiratory distress due to compression atelectasis. It is most often associated with mediastinal shift with subsequent hypoxia. CLE poses a diagnostic and therapeutic dilemma. We report a case of five-month-old infant of CLE requiring left lobectomy, who was previously being treated for pneumonia which was unresponsive to medical therapy...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29197400/evaluation-of-the-new-tnm-staging-system-for-thymic-malignancies-impact-on-indication-and-survival
#15
Michael Ried, Maria-Magdalena Eicher, Reiner Neu, Zsolt Sziklavari, Hans-Stefan Hofmann
BACKGROUND: The objective of this study is the evaluation of the Masaoka-Koga and the International Association for the Study of Lung Cancer (IASLC)/International Thymic Malignancy Interest Group (ITMIG) proposal for the new TNM-staging system on clinical implementation and prognosis of thymic malignancies. METHODS: A retrospective study of 76 patients who underwent surgery between January 2005 and December 2015 for thymoma. Kaplan-Meier survival analysis was used to determine overall and recurrence-free survival rates...
December 2, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29179902/mediastinal-epipericardial-fat-necrosis-an-overlooked-and-little-known-cause-of-acute-chest-pain-mimicking-acute-coronary-syndrome
#16
Gabriela Gayer
Necrosis of the fat adjacent to the heart, referred to as pericardial fat necrosis, epipericardial fat necrosis, and mediastinal fat necrosis, is a rare, self-limited condition. It presents as a sudden onset of severe chest pain that mimics symptoms of pulmonary embolism and acute coronary syndrome. Computed tomography (CT) findings are quite typical and consist of a round- or oval-shaped mass-like lesion containing soft tissue and fat density components in the cardiophrenic space. Lack of familiarity with this condition has led in the past to surgical interventions to remove the mass-like mediastinal fat necrosis...
December 2017: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/29143106/nonsuppressing-normal-thymus-on-chemical-shift-mr-imaging-and-anterior-mediastinal-lymphoma-differentiation-with-diffusion-weighted-mr-imaging-by-using-the-apparent-diffusion-coefficient
#17
Adriano Massimiliano Priola, Sandro Massimo Priola, Dario Gned, Maria Teresa Giraudo, Andrea Veltri
OBJECTIVES: To prospectively evaluate usefulness of the apparent diffusion coefficient (ADC) in differentiating anterior mediastinal lymphoma from nonsuppressing normal thymus on chemical-shift MR, and to look at the relationship between patient age and ADC. METHODS: Seventy-three young subjects (25 men, 48 women; age range, 9-29 years), who underwent chemical-shift MR and diffusion-weighted MR were divided into a normal thymus group (group A, 40 subjects), and a lymphoma group (group B, 33 patients)...
April 2018: European Radiology
https://www.readbyqxmd.com/read/29107084/evidence-for-m2-macrophages-in-granulomas-from-pulmonary-sarcoidosis-a-new-aspect-of-macrophage-heterogeneity
#18
Masoud Shamaei, Esmaeil Mortaz, Mihan Pourabdollah, Johan Garssen, Payam Tabarsi, Aliakbar Velayati, Ian M Adcock
BACKGROUND: Sarcoidosis is a granulomatous disease of unknown etiology. Macrophages play a key role in granuloma formation with the T cells, having a significant impact on macrophage polarization (M1 and M2) and the cellular composition of the granuloma. This study evaluates macrophage polarization in granulomas in pulmonary sarcoidosis. MATERIALS AND METHODS: Tissue specimens from the Department of Pathology biobank at the Masih Daneshvari Hospital were obtained...
January 2018: Human Immunology
https://www.readbyqxmd.com/read/29078613/the-athens-uniportal-video-assisted-thoracic-surgery-masterclass-an-ambitious-kickstarter
#19
Constantine Marios Soultanis, Diego Gonzalez Rivas, Konstantinos Konstantinidis, Konstantinos Siafakas
The shift from open to minimally invasive techniques in thoracic surgery has been dramatic during the past 10 years. Not only the feasibility, safety, reproducibility and oncologic efficacy of these techniques have been clearly demonstrated, but also their superiority concerning mortality, postoperative pain, postoperative quality of life and recovery. Thus, video-assisted thoracic surgery (VATS) is currently the procedure of choice for a wide variety of thoracic interventions, ranging from major pulmonary resections for lung cancer to thymectomy and mediastinal procedures, even to esophageal procedures...
2017: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29028157/transthoracic-catheter-drainage-for-large-symptomatic-congenital-pulmonary-airway-malformation
#20
Seong Hee Oh, Chae Young Kim, Byong Sop Lee, Dong Kwan Kim, Ellen Ai-Rhan Kim, Ki-Soo Kim
BACKGROUND: Surgical resection of large symptomatic congenital pulmonary airway malformation (CPAM) in newborns has high risks of mortality and postoperative morbidity. This study aimed to report the clinical outcomes of newborns who underwent percutaneous transthoracic catheter drainage (PTCD) of large symptomatic CPAM before surgical resection. METHODS: This was a retrospective, descriptive study based on review of the medical records of newborn infants who required surgical resection of large symptomatic CPAM at a single tertiary hospital from 2001 to 2017...
December 2017: Pediatric Pulmonology
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