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oxymetazoline in rhinosinusitis

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https://www.readbyqxmd.com/read/15182211/chronic-rhinosinusitis-management-for-optimal-outcomes
#1
REVIEW
Albertien A C Aukema, Wytske J Fokkens
Chronic rhinosinusitis is characterized by nasal purulence accompanied by malaise, postnasal drip and nasal dryness or crusting. It is a condition that is very difficult to treat and can be very disabling to the patients. A clinical diagnosis is based on history and evaluation with endoscopy, and computerized tomographic scanning. The etiology of chronic rhinosinusitis is multifactorial and comprises a vicious cycle of pathophysiological, anatomical, and constitutive factors. Predisposing factors include ciliary impairment, allergy, nasal polyposis, and immune deficiency...
2004: Treatments in Respiratory Medicine
https://www.readbyqxmd.com/read/11889391/the-effects-of-topical-agents-of-fluticasone-propionate-oxymetazoline-and-3-and-0-9-sodium-chloride-solutions-on-mucociliary-clearance-in-the-therapy-of-acute-bacterial-rhinosinusitis-in-vivo
#2
COMPARATIVE STUDY
Selçuk Inanli, Ozmen Oztürk, Mukadder Korkmaz, Alper Tutkun, Cağlar Batman
OBJECTIVES: The aims of the study were to determine: 1) how mucociliary activity in acute bacterial rhinosinusitis is affected; 2) how this activity is changed by therapy; 3) the effects of topical agents on mucociliary clearance, and 4) the most appropriate topical agent(s) to be used in the therapy of sinusitis. STUDY DESIGN: Five groups of patients with acute bacterial rhinosinusitis were studied prospectively. METHODS: All patients had 500 mg oral amoxicillin and 125 mg oral clavulanic acid preparations given three times daily for 3 weeks...
February 2002: Laryngoscope
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