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Carlos Fernández-del castillo

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https://www.readbyqxmd.com/read/27865286/intraductal-papillary-mucinous-neoplasm-of-the-pancreas
#1
REVIEW
Zhi Ven Fong, Carlos Fernández-Del Castillo
The incidence of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas has been rising in the past 2 decades, driven mainly by the widespread use of cross-sectional imaging. IPMNs are intraductal mucin-producing neoplasms that involve the main pancreatic duct or its side branches and lack the ovarian stroma typically seen in mucinous cystic neoplasms. The International Association of Pancreatology released consensus guidelines in 2006 and 2012 providing clinical algorithms based on IPMN features and risk of malignancy...
December 2016: Surgical Clinics of North America
https://www.readbyqxmd.com/read/27846142/predictors-of-early-mortality-after-surgical-resection-of-pancreatic-adenocarcinoma-in-the-era-of-neoadjuvant-treatment
#2
Ryan D Nipp, Andrea Zanconato, Hui Zheng, Cristina R Ferrone, Keith D Lillemoe, Jennifer Y Wo, Theodore S Hong, Jeffrey W Clark, David P Ryan, Carlos Fernandez-Del Castillo
OBJECTIVES: Neoadjuvant treatments are increasingly used for patients with pancreatic ductal adenocarcinoma (PDAC), yet some experience early mortality after resection. We sought to identify predictors of early mortality after PDAC resection and determine their interaction with neoadjuvant therapy. METHODS: We performed a retrospective study of patients with PDAC resection from March 2011 to March 2014. We compared those who died within one year after surgery to those living beyond 1 year, and those who received neoadjuvant therapy to those taken directly to surgery...
November 11, 2016: Pancreas
https://www.readbyqxmd.com/read/27835023/correlated-event-by-event-fluctuations-of-flow-harmonics-in-pb-pb-collisions-at-sqrt-s_-nn-2-76%C3%A2-%C3%A2-tev
#3
J Adam, D Adamová, M M Aggarwal, G Aglieri Rinella, M Agnello, N Agrawal, Z Ahammed, S Ahmad, S U Ahn, S Aiola, A Akindinov, S N Alam, D S D Albuquerque, D Aleksandrov, B Alessandro, D Alexandre, R Alfaro Molina, A Alici, A Alkin, J R M Almaraz, J Alme, T Alt, S Altinpinar, I Altsybeev, C Alves Garcia Prado, C Andrei, A Andronic, V Anguelov, T Antičić, F Antinori, P Antonioli, L Aphecetche, H Appelshäuser, S Arcelli, R Arnaldi, O W Arnold, I C Arsene, M Arslandok, B Audurier, A Augustinus, R Averbeck, M D Azmi, A Badalà, Y W Baek, S Bagnasco, R Bailhache, R Bala, S Balasubramanian, A Baldisseri, R C Baral, A M Barbano, R Barbera, F Barile, G G Barnaföldi, L S Barnby, V Barret, P Bartalini, K Barth, J Bartke, E Bartsch, M Basile, N Bastid, S Basu, B Bathen, G Batigne, A Batista Camejo, B Batyunya, P C Batzing, I G Bearden, H Beck, C Bedda, N K Behera, I Belikov, F Bellini, H Bello Martinez, R Bellwied, R Belmont, E Belmont-Moreno, L G E Beltran, V Belyaev, G Bencedi, S Beole, I Berceanu, A Bercuci, Y Berdnikov, D Berenyi, R A Bertens, D Berzano, L Betev, A Bhasin, I R Bhat, A K Bhati, B Bhattacharjee, J Bhom, L Bianchi, N Bianchi, C Bianchin, J Bielčík, J Bielčíková, A Bilandzic, G Biro, R Biswas, S Biswas, S Bjelogrlic, J T Blair, D Blau, C Blume, F Bock, A Bogdanov, H Bøggild, L Boldizsár, M Bombara, J Book, H Borel, A Borissov, M Borri, F Bossú, E Botta, C Bourjau, P Braun-Munzinger, M Bregant, T Breitner, T A Broker, T A Browning, M Broz, E J Brucken, E Bruna, G E Bruno, D Budnikov, H Buesching, S Bufalino, P Buncic, O Busch, Z Buthelezi, J B Butt, J T Buxton, J Cabala, D Caffarri, X Cai, H Caines, L Calero Diaz, A Caliva, E Calvo Villar, P Camerini, F Carena, W Carena, F Carnesecchi, J Castillo Castellanos, A J Castro, E A R Casula, C Ceballos Sanchez, J Cepila, P Cerello, J Cerkala, B Chang, S Chapeland, M Chartier, J L Charvet, S Chattopadhyay, S Chattopadhyay, A Chauvin, V Chelnokov, M Cherney, C Cheshkov, B Cheynis, V Chibante Barroso, D D Chinellato, S Cho, P Chochula, K Choi, M Chojnacki, S Choudhury, P Christakoglou, C H Christensen, P Christiansen, T Chujo, S U Chung, C Cicalo, L Cifarelli, F Cindolo, J Cleymans, F Colamaria, D Colella, A Collu, M Colocci, G Conesa Balbastre, Z Conesa Del Valle, M E Connors, J G Contreras, T M Cormier, Y Corrales Morales, I Cortés Maldonado, P Cortese, M R Cosentino, F Costa, P Crochet, R Cruz Albino, E Cuautle, L Cunqueiro, T Dahms, A Dainese, M C Danisch, A Danu, D Das, I Das, S Das, A Dash, S Dash, S De, A De Caro, G de Cataldo, C de Conti, J de Cuveland, A De Falco, D De Gruttola, N De Marco, S De Pasquale, R D De Souza, A Deisting, A Deloff, E Dénes, C Deplano, P Dhankher, D Di Bari, A Di Mauro, P Di Nezza, B Di Ruzza, M A Diaz Corchero, T Dietel, P Dillenseger, R Divià, Ø Djuvsland, A Dobrin, D Domenicis Gimenez, B Dönigus, O Dordic, T Drozhzhova, A K Dubey, A Dubla, L Ducroux, P Dupieux, R J Ehlers, D Elia, E Endress, H Engel, E Epple, B Erazmus, I Erdemir, F Erhardt, B Espagnon, M Estienne, S Esumi, J Eum, D Evans, S Evdokimov, G Eyyubova, L Fabbietti, D Fabris, J Faivre, A Fantoni, M Fasel, L Feldkamp, A Feliciello, G Feofilov, J Ferencei, A Fernández Téllez, E G Ferreiro, A Ferretti, A Festanti, V J G Feuillard, J Figiel, M A S Figueredo, S Filchagin, D Finogeev, F M Fionda, E M Fiore, M G Fleck, M Floris, S Foertsch, P Foka, S Fokin, E Fragiacomo, A Francescon, A Francisco, U Frankenfeld, G G Fronze, U Fuchs, C Furget, A Furs, M Fusco Girard, J J Gaardhøje, M Gagliardi, A M Gago, K Gajdosova, M Gallio, C D Galvan, D R Gangadharan, P Ganoti, C Gao, C Garabatos, E Garcia-Solis, C Gargiulo, P Gasik, E F Gauger, M Germain, M Gheata, P Ghosh, S K Ghosh, P Gianotti, P Giubellino, P Giubilato, E Gladysz-Dziadus, P Glässel, D M Goméz Coral, A Gomez Ramirez, A S Gonzalez, V Gonzalez, P González-Zamora, S Gorbunov, L Görlich, S Gotovac, V Grabski, O A Grachov, L K Graczykowski, K L Graham, A Grelli, A Grigoras, C Grigoras, V Grigoriev, A Grigoryan, S Grigoryan, B Grinyov, N Grion, J M Gronefeld, J F Grosse-Oetringhaus, R Grosso, L Gruber, F Guber, R Guernane, B Guerzoni, K Gulbrandsen, T Gunji, A Gupta, R Gupta, R Haake, Ø Haaland, C Hadjidakis, M Haiduc, H Hamagaki, G Hamar, J C Hamon, J W Harris, A Harton, D Hatzifotiadou, S Hayashi, S T Heckel, E Hellbär, H Helstrup, A Herghelegiu, G Herrera Corral, B A Hess, K F Hetland, H Hillemanns, B Hippolyte, D Horak, R Hosokawa, P Hristov, C Hughes, T J Humanic, N Hussain, T Hussain, D Hutter, D S Hwang, R Ilkaev, M Inaba, E Incani, M Ippolitov, M Irfan, M Ivanov, V Ivanov, V Izucheev, B Jacak, N Jacazio, P M Jacobs, M B Jadhav, S Jadlovska, J Jadlovsky, C Jahnke, M J Jakubowska, H J Jang, M A Janik, P H S Y Jayarathna, C Jena, S Jena, R T Jimenez Bustamante, P G Jones, A Jusko, P Kalinak, A Kalweit, J Kamin, J H Kang, V Kaplin, S Kar, A Karasu Uysal, O Karavichev, T Karavicheva, L Karayan, E Karpechev, U Kebschull, R Keidel, D L D Keijdener, M Keil, M Mohisin Khan, P Khan, S A Khan, A Khanzadeev, Y Kharlov, B Kileng, D W Kim, D J Kim, D Kim, H Kim, J S Kim, J Kim, M Kim, S Kim, T Kim, S Kirsch, I Kisel, S Kiselev, A Kisiel, G Kiss, J L Klay, C Klein, J Klein, C Klein-Bösing, S Klewin, A Kluge, M L Knichel, A G Knospe, C Kobdaj, M Kofarago, T Kollegger, A Kolojvari, V Kondratiev, N Kondratyeva, E Kondratyuk, A Konevskikh, M Kopcik, M Kour, C Kouzinopoulos, O Kovalenko, V Kovalenko, M Kowalski, G Koyithatta Meethaleveedu, I Králik, A Kravčáková, M Krivda, F Krizek, E Kryshen, M Krzewicki, A M Kubera, V Kučera, C Kuhn, P G Kuijer, A Kumar, J Kumar, L Kumar, S Kumar, P Kurashvili, A Kurepin, A B Kurepin, A Kuryakin, M J Kweon, Y Kwon, S L La Pointe, P La Rocca, P Ladron de Guevara, C Lagana Fernandes, I Lakomov, R Langoy, K Lapidus, C Lara, A Lardeux, A Lattuca, E Laudi, R Lea, L Leardini, G R Lee, S Lee, F Lehas, S Lehner, R C Lemmon, V Lenti, E Leogrande, I León Monzón, H León Vargas, M Leoncino, P Lévai, S Li, X Li, J Lien, R Lietava, S Lindal, V Lindenstruth, C Lippmann, M A Lisa, H M Ljunggren, D F Lodato, P I Loenne, V Loginov, C Loizides, X Lopez, E López Torres, A Lowe, P Luettig, M Lunardon, G Luparello, T H Lutz, A Maevskaya, M Mager, S Mahajan, S M Mahmood, A Maire, R D Majka, M Malaev, I Maldonado Cervantes, L Malinina, D Mal'Kevich, P Malzacher, A Mamonov, V Manko, F Manso, V Manzari, M Marchisone, J Mareš, G V Margagliotti, A Margotti, J Margutti, A Marín, C Markert, M Marquard, N A Martin, J Martin Blanco, P Martinengo, M I Martínez, G Martínez García, M Martinez Pedreira, A Mas, S Masciocchi, M Masera, A Masoni, A Mastroserio, A Matyja, C Mayer, J Mazer, M A Mazzoni, D Mcdonald, F Meddi, Y Melikyan, A Menchaca-Rocha, E Meninno, J Mercado Pérez, M Meres, Y Miake, M M Mieskolainen, K Mikhaylov, L Milano, J Milosevic, A Mischke, A N Mishra, D Miśkowiec, J Mitra, C M Mitu, N Mohammadi, B Mohanty, L Molnar, L Montaño Zetina, E Montes, D A Moreira De Godoy, L A P Moreno, S Moretto, A Morreale, A Morsch, V Muccifora, E Mudnic, D Mühlheim, S Muhuri, M Mukherjee, J D Mulligan, M G Munhoz, K Münning, R H Munzer, H Murakami, S Murray, L Musa, J Musinsky, B Naik, R Nair, B K Nandi, R Nania, E Nappi, M U Naru, H Natal da Luz, C Nattrass, S R Navarro, K Nayak, R Nayak, T K Nayak, S Nazarenko, A Nedosekin, L Nellen, F Ng, M Nicassio, M Niculescu, J Niedziela, B S Nielsen, S Nikolaev, S Nikulin, V Nikulin, F Noferini, P Nomokonov, G Nooren, J C C Noris, J Norman, A Nyanin, J Nystrand, H Oeschler, S Oh, S K Oh, A Ohlson, A Okatan, T Okubo, J Oleniacz, A C Oliveira Da Silva, M H Oliver, J Onderwaater, C Oppedisano, R Orava, M Oravec, A Ortiz Velasquez, A Oskarsson, J Otwinowski, K Oyama, M Ozdemir, Y Pachmayer, D Pagano, P Pagano, G Paić, S K Pal, J Pan, A K Pandey, V Papikyan, G S Pappalardo, P Pareek, W J Park, S Parmar, A Passfeld, V Paticchio, R N Patra, B Paul, H Pei, T Peitzmann, X Peng, H Pereira Da Costa, D Peresunko, E Perez Lezama, V Peskov, Y Pestov, V Petráček, V Petrov, M Petrovici, C Petta, S Piano, M Pikna, P Pillot, L O D L Pimentel, O Pinazza, L Pinsky, D B Piyarathna, M Płoskoń, M Planinic, J Pluta, S Pochybova, P L M Podesta-Lerma, M G Poghosyan, B Polichtchouk, N Poljak, W Poonsawat, A Pop, H Poppenborg, S Porteboeuf-Houssais, J Porter, J Pospisil, S K Prasad, R Preghenella, F Prino, C A Pruneau, I Pshenichnov, M Puccio, G Puddu, P Pujahari, V Punin, J Putschke, H Qvigstad, A Rachevski, S Raha, S Rajput, J Rak, A Rakotozafindrabe, L Ramello, F Rami, R Raniwala, S Raniwala, S S Räsänen, B T Rascanu, D Rathee, K F Read, K Redlich, R J Reed, A Rehman, P Reichelt, F Reidt, X Ren, R Renfordt, A R Reolon, A Reshetin, K Reygers, V Riabov, R A Ricci, T Richert, M Richter, P Riedler, W Riegler, F Riggi, C Ristea, E Rocco, M Rodríguez Cahuantzi, A Rodriguez Manso, K Røed, E Rogochaya, D Rohr, D Röhrich, F Ronchetti, L Ronflette, P Rosnet, A Rossi, F Roukoutakis, A Roy, C Roy, P Roy, A J Rubio Montero, R Rui, R Russo, E Ryabinkin, Y Ryabov, A Rybicki, S Saarinen, S Sadhu, S Sadovsky, K Šafařík, B Sahlmuller, P Sahoo, R Sahoo, S Sahoo, P K Sahu, J Saini, S Sakai, M A Saleh, J Salzwedel, S Sambyal, V Samsonov, L Šándor, A Sandoval, M Sano, D Sarkar, N Sarkar, P Sarma, E Scapparone, F Scarlassara, C Schiaua, R Schicker, C Schmidt, H R Schmidt, M Schmidt, S Schuchmann, J Schukraft, M Schulc, Y Schutz, K Schwarz, K Schweda, G Scioli, E Scomparin, R Scott, M Šefčík, J E Seger, Y Sekiguchi, D Sekihata, I Selyuzhenkov, K Senosi, S Senyukov, E Serradilla, A Sevcenco, A Shabanov, A Shabetai, O Shadura, R Shahoyan, M I Shahzad, A Shangaraev, A Sharma, M Sharma, M Sharma, N Sharma, A I Sheikh, K Shigaki, Q Shou, K Shtejer, Y Sibiriak, S Siddhanta, K M Sielewicz, T Siemiarczuk, D Silvermyr, C Silvestre, G Simatovic, G Simonetti, R Singaraju, R Singh, V Singhal, T Sinha, B Sitar, M Sitta, T B Skaali, M Slupecki, N Smirnov, R J M Snellings, T W Snellman, J Song, M Song, Z Song, F Soramel, S Sorensen, F Sozzi, M Spacek, E Spiriti, I Sputowska, M Spyropoulou-Stassinaki, J Stachel, I Stan, P Stankus, E Stenlund, G Steyn, J H Stiller, D Stocco, P Strmen, A A P Suaide, T Sugitate, C Suire, M Suleymanov, M Suljic, R Sultanov, M Šumbera, S Sumowidagdo, A Szabo, I Szarka, A Szczepankiewicz, M Szymanski, U Tabassam, J Takahashi, G J Tambave, N Tanaka, M Tarhini, M Tariq, M G Tarzila, A Tauro, G Tejeda Muñoz, A Telesca, K Terasaki, C Terrevoli, B Teyssier, J Thäder, D Thakur, D Thomas, R Tieulent, A Tikhonov, A R Timmins, A Toia, S Trogolo, G Trombetta, V Trubnikov, W H Trzaska, T Tsuji, A Tumkin, R Turrisi, T S Tveter, K Ullaland, A Uras, G L Usai, A Utrobicic, M Vala, L Valencia Palomo, S Vallero, J Van Der Maarel, J W Van Hoorne, M van Leeuwen, T Vanat, P Vande Vyvre, D Varga, A Vargas, M Vargyas, R Varma, M Vasileiou, A Vasiliev, A Vauthier, O Vázquez Doce, V Vechernin, A M Veen, M Veldhoen, A Velure, E Vercellin, S Vergara Limón, R Vernet, M Verweij, L Vickovic, J Viinikainen, Z Vilakazi, O Villalobos Baillie, A Villatoro Tello, A Vinogradov, L Vinogradov, Y Vinogradov, T Virgili, V Vislavicius, Y P Viyogi, A Vodopyanov, M A Völkl, K Voloshin, S A Voloshin, G Volpe, B von Haller, I Vorobyev, D Vranic, J Vrláková, B Vulpescu, B Wagner, J Wagner, H Wang, M Wang, D Watanabe, Y Watanabe, M Weber, S G Weber, D F Weiser, J P Wessels, U Westerhoff, A M Whitehead, J Wiechula, J Wikne, G Wilk, J Wilkinson, M C S Williams, B Windelband, M Winn, P Yang, S Yano, Z Yasin, Z Yin, H Yokoyama, I-K Yoo, J H Yoon, V Yurchenko, A Zaborowska, V Zaccolo, A Zaman, C Zampolli, H J C Zanoli, S Zaporozhets, N Zardoshti, A Zarochentsev, P Závada, N Zaviyalov, H Zbroszczyk, I S Zgura, M Zhalov, H Zhang, X Zhang, Y Zhang, C Zhang, Z Zhang, C Zhao, N Zhigareva, D Zhou, Y Zhou, Z Zhou, H Zhu, J Zhu, A Zichichi, A Zimmermann, M B Zimmermann, G Zinovjev, M Zyzak
We report the measurements of correlations between event-by-event fluctuations of amplitudes of anisotropic flow harmonics in nucleus-nucleus collisions, obtained for the first time using a new analysis method based on multiparticle cumulants in mixed harmonics. This novel method is robust against systematic biases originating from nonflow effects and by construction any dependence on symmetry planes is eliminated. We demonstrate that correlations of flow harmonics exhibit a better sensitivity to medium properties than the individual flow harmonics...
October 28, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27748720/minutes-of-the-business-meeting-of-the-american-pancreatic-association-friday-november-6-2015-san-diego-california
#4
Anirban Maitra, Carlos Fernández-Del Castillo, Stephen J Pandol, Ashok K Saluja, Darwin L Conwell, Miklós Sahin-Tóth, Margaret A Tempero, Vay Liang W Go
No abstract text is available yet for this article.
November 2016: Pancreas
https://www.readbyqxmd.com/read/27748717/2016-american-pancreatic-association-presidential-address-forging-interactions-to-advance-the-field
#5
Carlos Fernández-Del Castillo
No abstract text is available yet for this article.
November 2016: Pancreas
https://www.readbyqxmd.com/read/27740973/intraoperative-radiotherapy-in-the-era-of-intensive-neoadjuvant-chemotherapy-and-chemoradiotherapy-for-pancreatic-adenocarcinoma
#6
Florence K Keane, Jennifer Y Wo, Cristina R Ferrone, Jeffrey W Clark, Lawrence S Blaszkowsky, Jill N Allen, Eunice L Kwak, David P Ryan, Keith D Lillemoe, Carlos Fernandez-Del Castillo, Theodore S Hong
OBJECTIVES: Improved outcomes with FOLFIRINOX or gemcitabine with nab-paclitaxel in the treatment of metastatic pancreatic adenocarcinoma (PDAC) have prompted incorporation of these regimens into neoadjuvant treatment of locally advanced unresectable PDAC. Whereas some patients remain unresectable on surgical exploration, others are able to undergo resection after intensive neoadjuvant treatment. We evaluated outcomes and toxicity associated with use of intensive neoadjuvant treatment followed by intraoperative radiotherapy (IORT) in combination with resection or exploratory laparotomy...
October 12, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27686460/esicm-lives-2016-part-two-milan-italy-1-5-october-2016
#7
S Sivakumar, F S Taccone, K A Desai, C Lazaridis, M Skarzynski, M Sekhon, W Henderson, D Griesdale, L Chapple, A Deane, L Williams, R Strickland, K Lange, D Heyland, M Chapman, M J Rowland, P Garry, J Westbrook, R Corkill, C A Antoniades, K T Pattinson, G Fatania, A J Strong, R B Myers, C Lazaridis, C M Jermaine, C S Robertson, C G Rusin, J Hofmeijer, L Sondag, M C Tjepkema-Cloostermans, A Beishuizen, F H Bosch, M J A M van Putten, L Carteron, C Patet, D Solari, M Oddo, M A Ali, C Dias, R Almeida, A Vaz-Ferreira, J Silva, E Monteiro, A Cerejo, A P Rocha, A A Elsayed, A M Abougabal, B N Beshey, K M Alzahaby, S Pozzebon, A Blandino Ortiz, S Cristallini, O Lheureux, A Brasseur, J L Vincent, J Creteur, F S Taccone, M Hravnak, K Yousef, Y Chang, E Crago, R M Friedlander, S A Abdelmonem, S A Tahon, T A Helmy, H S Meligy, F Puig, I Dunn-Siegrist, J Pugin, S Gupta, D Govil, S Srinivasan, S J Patel, J K N, A Gupta, D S Tomar, M Shafi, R Harne, D P Arora, N Talwar, S Mazumdar, E E Papakrivou, D Makris, E Manoulakas, B Tsolaki, B Karadodas, E Zakynthinos, I Palacios Garcia, A Diaz Martin, V Sanchez Encinares, M Pachón Ibañez, J Garnacho Montero, G Labrador, T Cebrero Cangueiro, V Poulose, J Koh, J W Kam, H Yeter, A Kara, O Aktepe, A Topeli, I Tsolakoglou, G Intas, P Stergiannis, A A Kolaros, E Chalari, E Athanasiadou, A Martika, G Fildisis, V Faivre, C Mengelle, B Favier, D Payen, A Poppe, M S Winkler, E Mudersbach, J Schreiber, M L Wruck, E Schwedhelm, S Kluge, C Zöllner, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, A García-de la Torre, M V de la Torre-Prados, T Tsvetanova-Spasova, P Nuevo-Ortega, C Rueda-Molina, A Fernández-Porcel, E Camara-Sola, L Salido-Díaz, A García-Alcántara, T Tavladaki, A M Spanaki, H Dimitriou, E Kondili, C Choulaki, D E Meleti, D Kafetzopoulos, D Georgopoulos, G Briassoulis, B Suberviola, J Riera, L Rellan, M Sanchez, J C Robles, E Lopez, R Vicente, E Miñambres, M 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No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27523981/loss-of-trefoil-factor-2-from-pancreatic-duct-glands-promotes-formation-of-intraductal-papillary-mucinous-neoplasms-in-mice
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Junpei Yamaguchi, Mari Mino-Kenudson, Andrew S Liss, Sanjib Chowdhury, Timothy C Wang, Carlos Fernández-Del Castillo, Keith D Lillemoe, Andrew L Warshaw, Sarah P Thayer
BACKGROUND & AIMS: Little is known about the origin of pancreatic intraductal papillary mucinous neoplasms (IPMN). Pancreatic duct glands (PDGs) are gland-like outpouches budding off the main pancreatic ducts that function as a progenitor niche for the ductal epithelium; they express gastric mucins and have characteristics of side-branch IPMNs. We investigated whether PDGs are a precursor compartment for IPMNs and the role of Trefoil factor family 2 (TFF2)-a protein expressed by PDGs and the gastric mucosa that are involved in epithelial repair and tumor suppression...
December 2016: Gastroenterology
https://www.readbyqxmd.com/read/27471432/identification-of-boosted-hadronically-decaying-w-bosons-and-comparisons-with-atlas-data-taken-at-formula-see-text-%C3%A2-tev
#9
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Nemecek, P Nemethy, A A Nepomuceno, M Nessi, M S Neubauer, M Neumann, R M Neves, P Nevski, P R Newman, D H Nguyen, R B Nickerson, R Nicolaidou, B Nicquevert, J Nielsen, N Nikiforou, A Nikiforov, V Nikolaenko, I Nikolic-Audit, K Nikolopoulos, J K Nilsen, P Nilsson, Y Ninomiya, A Nisati, R Nisius, T Nobe, M Nomachi, I Nomidis, T Nooney, S Norberg, M Nordberg, O Novgorodova, S Nowak, M Nozaki, L Nozka, K Ntekas, G Nunes Hanninger, T Nunnemann, E Nurse, F Nuti, B J O'Brien, F O'grady, D C O'Neil, V O'Shea, F G Oakham, H Oberlack, T Obermann, J Ocariz, A Ochi, I Ochoa, J P Ochoa-Ricoux, S Oda, S Odaka, H Ogren, A Oh, S H Oh, C C Ohm, H Ohman, H Oide, W Okamura, H Okawa, Y Okumura, T Okuyama, A Olariu, S A Olivares Pino, D Oliveira Damazio, A Olszewski, J Olszowska, A Onofre, K Onogi, P U E Onyisi, C J Oram, M J Oreglia, Y Oren, D Orestano, N Orlando, C Oropeza Barrera, R S Orr, B Osculati, R Ospanov, G Otero Y Garzon, H Otono, M Ouchrif, F Ould-Saada, A Ouraou, K P Oussoren, Q Ouyang, A Ovcharova, M Owen, R E Owen, V E Ozcan, N Ozturk, K Pachal, A Pacheco Pages, C Padilla Aranda, M Pagáčová, S Pagan Griso, E Paganis, F Paige, P Pais, K Pajchel, G Palacino, S Palestini, M Palka, D Pallin, A Palma, Y B Pan, E Panagiotopoulou, C E Pandini, J G Panduro Vazquez, P Pani, S Panitkin, D Pantea, L Paolozzi, Th D Papadopoulou, K Papageorgiou, A Paramonov, D Paredes Hernandez, M A Parker, K A Parker, F Parodi, J A Parsons, U Parzefall, E Pasqualucci, S Passaggio, F Pastore, Fr Pastore, G Pásztor, S Pataraia, N D Patel, J R Pater, T Pauly, J Pearce, B Pearson, L E Pedersen, M Pedersen, S Pedraza Lopez, R Pedro, S V Peleganchuk, D Pelikan, O Penc, C Peng, H Peng, B Penning, J Penwell, D V Perepelitsa, E Perez Codina, M T Pérez García-Estañ, L Perini, H Pernegger, S Perrella, R Peschke, V D Peshekhonov, K Peters, R F Y Peters, B A Petersen, T C Petersen, E Petit, A Petridis, C Petridou, P Petroff, E Petrolo, F Petrucci, N E Pettersson, R Pezoa, P W Phillips, G Piacquadio, E Pianori, A Picazio, E Piccaro, M Piccinini, M A Pickering, R Piegaia, D T Pignotti, J E Pilcher, A D Pilkington, J Pina, M Pinamonti, J L Pinfold, A Pingel, S Pires, H Pirumov, M Pitt, C Pizio, L Plazak, M-A Pleier, V Pleskot, E Plotnikova, P Plucinski, D Pluth, R Poettgen, L Poggioli, D Pohl, G Polesello, A Poley, A Policicchio, R Polifka, A Polini, C S Pollard, V Polychronakos, K Pommès, L Pontecorvo, B G Pope, G A Popeneciu, D S Popovic, A Poppleton, S Pospisil, K Potamianos, I N Potrap, C J Potter, C T Potter, G Poulard, J Poveda, V Pozdnyakov, P Pralavorio, A Pranko, S Prasad, S Prell, D Price, L E Price, M Primavera, S Prince, M Proissl, K Prokofiev, F Prokoshin, E Protopapadaki, S Protopopescu, J Proudfoot, M Przybycien, E Ptacek, D Puddu, E Pueschel, D Puldon, M Purohit, P Puzo, J Qian, G Qin, Y Qin, A Quadt, D R Quarrie, W B Quayle, M Queitsch-Maitland, D Quilty, S Raddum, V Radeka, V Radescu, S K Radhakrishnan, P Radloff, P Rados, F Ragusa, G Rahal, S Rajagopalan, M Rammensee, C Rangel-Smith, F Rauscher, S Rave, T Ravenscroft, M Raymond, A L Read, N P Readioff, D M Rebuzzi, A Redelbach, G Redlinger, R Reece, K Reeves, L Rehnisch, J Reichert, H Reisin, C Rembser, H Ren, A Renaud, M Rescigno, S Resconi, O L Rezanova, P Reznicek, R Rezvani, R Richter, S Richter, E Richter-Was, O Ricken, M Ridel, P Rieck, C J Riegel, J Rieger, O Rifki, M Rijssenbeek, A Rimoldi, L Rinaldi, B Ristić, E Ritsch, I Riu, F Rizatdinova, E Rizvi, S H Robertson, A Robichaud-Veronneau, D Robinson, J E M Robinson, A Robson, C Roda, S Roe, O Røhne, S Rolli, A Romaniouk, M Romano, S M Romano Saez, E Romero Adam, N Rompotis, M Ronzani, L Roos, E Ros, S Rosati, K Rosbach, P Rose, P L Rosendahl, O Rosenthal, V Rossetti, E Rossi, L P Rossi, J H N Rosten, R Rosten, M Rotaru, I Roth, J Rothberg, D Rousseau, C R Royon, A Rozanov, Y Rozen, X Ruan, F Rubbo, I Rubinskiy, V I Rud, C Rudolph, M S Rudolph, F Rühr, A Ruiz-Martinez, Z Rurikova, N A Rusakovich, A Ruschke, H L Russell, J P Rutherfoord, N Ruthmann, Y F Ryabov, M Rybar, G Rybkin, N C Ryder, A F Saavedra, G Sabato, S Sacerdoti, A Saddique, H F-W Sadrozinski, R Sadykov, F Safai Tehrani, P Saha, M Sahinsoy, M Saimpert, T Saito, H Sakamoto, Y Sakurai, G Salamanna, A Salamon, J E Salazar Loyola, M Saleem, D Salek, P H Sales De Bruin, D Salihagic, A Salnikov, J Salt, D Salvatore, F Salvatore, A Salvucci, A Salzburger, D Sammel, D Sampsonidis, A Sanchez, J Sánchez, V Sanchez Martinez, H Sandaker, R L Sandbach, H G Sander, M P Sanders, M Sandhoff, C Sandoval, R Sandstroem, D P C Sankey, M Sannino, A Sansoni, C Santoni, R Santonico, H Santos, I Santoyo Castillo, K Sapp, A Sapronov, J G Saraiva, B Sarrazin, O Sasaki, Y Sasaki, K Sato, G Sauvage, E Sauvan, G Savage, P Savard, C Sawyer, L Sawyer, J Saxon, C Sbarra, A Sbrizzi, T Scanlon, D A Scannicchio, M Scarcella, V Scarfone, J Schaarschmidt, P Schacht, D Schaefer, R Schaefer, J Schaeffer, S Schaepe, S Schaetzel, U Schäfer, A C Schaffer, D Schaile, R D Schamberger, V Scharf, V A Schegelsky, D Scheirich, M Schernau, C Schiavi, C Schillo, M Schioppa, S Schlenker, K Schmieden, C Schmitt, S Schmitt, S Schmitt, B Schneider, Y J Schnellbach, U Schnoor, L Schoeffel, A Schoening, B D Schoenrock, E Schopf, A L S Schorlemmer, M Schott, D Schouten, J Schovancova, S Schramm, M Schreyer, N Schuh, M J Schultens, H-C Schultz-Coulon, H Schulz, M Schumacher, B A Schumm, Ph Schune, C Schwanenberger, A Schwartzman, T A Schwarz, Ph Schwegler, H Schweiger, Ph Schwemling, R Schwienhorst, J Schwindling, T Schwindt, F G Sciacca, E Scifo, G Sciolla, F Scuri, F Scutti, J Searcy, G Sedov, E Sedykh, P Seema, S C Seidel, A Seiden, F Seifert, J M Seixas, G Sekhniaidze, K Sekhon, S J Sekula, D M Seliverstov, N Semprini-Cesari, C Serfon, L Serin, L Serkin, T Serre, M Sessa, R Seuster, H Severini, T Sfiligoj, F Sforza, A Sfyrla, E Shabalina, M Shamim, L Y Shan, R Shang, J T Shank, M Shapiro, P B Shatalov, K Shaw, S M Shaw, A Shcherbakova, C Y Shehu, P Sherwood, L Shi, S Shimizu, C O Shimmin, M Shimojima, M Shiyakova, A Shmeleva, D Shoaleh Saadi, M J Shochet, S Shojaii, S Shrestha, E Shulga, M A Shupe, S Shushkevich, P Sicho, P E Sidebo, O Sidiropoulou, D Sidorov, A Sidoti, F Siegert, Dj Sijacki, J Silva, Y Silver, S B Silverstein, V Simak, O Simard, Lj Simic, S Simion, E Simioni, B Simmons, D Simon, P Sinervo, N B Sinev, M Sioli, G Siragusa, A N Sisakyan, S Yu Sivoklokov, J Sjölin, T B Sjursen, M B Skinner, H P Skottowe, P Skubic, M Slater, T Slavicek, M Slawinska, K Sliwa, V Smakhtin, B H Smart, L Smestad, S Yu Smirnov, Y Smirnov, L N Smirnova, O Smirnova, M N K Smith, R W Smith, M Smizanska, K Smolek, A A Snesarev, G Snidero, S Snyder, R Sobie, F Socher, A Soffer, D A Soh, G Sokhrannyi, C A Solans, M Solar, J Solc, E Yu Soldatov, U Soldevila, A A Solodkov, A Soloshenko, O V Solovyanov, V Solovyev, P Sommer, H Y Song, N Soni, A Sood, A Sopczak, B Sopko, V Sopko, V Sorin, D Sosa, M Sosebee, C L Sotiropoulou, R Soualah, A M Soukharev, D South, B C Sowden, S Spagnolo, M Spalla, M Spangenberg, F Spanò, W R Spearman, D Sperlich, F Spettel, R Spighi, G Spigo, L A Spiller, M Spousta, R D St Denis, A Stabile, S Staerz, J Stahlman, R Stamen, S Stamm, E Stanecka, C Stanescu, M Stanescu-Bellu, M M Stanitzki, S Stapnes, E A Starchenko, J Stark, P Staroba, P Starovoitov, R Staszewski, P Steinberg, B Stelzer, H J Stelzer, O Stelzer-Chilton, H Stenzel, G A Stewart, J A Stillings, M C Stockton, M Stoebe, G Stoicea, P Stolte, S Stonjek, A R Stradling, A Straessner, M E Stramaglia, J Strandberg, S Strandberg, A Strandlie, E Strauss, M Strauss, P Strizenec, R Ströhmer, D M Strom, R Stroynowski, A Strubig, S A Stucci, B Stugu, N A Styles, D Su, J Su, R Subramaniam, A Succurro, Y Sugaya, M Suk, V V Sulin, S Sultansoy, T Sumida, S Sun, X Sun, J E Sundermann, K Suruliz, G Susinno, M R Sutton, S Suzuki, M Svatos, M Swiatlowski, I Sykora, T Sykora, D Ta, C Taccini, K Tackmann, J Taenzer, A Taffard, R Tafirout, N Taiblum, H Takai, R Takashima, H Takeda, T Takeshita, Y Takubo, M Talby, A A Talyshev, J Y C Tam, K G Tan, J Tanaka, R Tanaka, S Tanaka, B B Tannenwald, N Tannoury, S Tapia Araya, S Tapprogge, S Tarem, F Tarrade, G F Tartarelli, P Tas, M Tasevsky, T Tashiro, E Tassi, A Tavares Delgado, Y Tayalati, F E Taylor, G N Taylor, P T E Taylor, W Taylor, F A Teischinger, M Teixeira Dias Castanheira, P Teixeira-Dias, K K Temming, D Temple, H Ten Kate, P K Teng, J J Teoh, F Tepel, S Terada, K Terashi, J Terron, S Terzo, M Testa, R J Teuscher, T Theveneaux-Pelzer, J P Thomas, J Thomas-Wilsker, E N Thompson, P D Thompson, R J Thompson, A S Thompson, L A Thomsen, E Thomson, M Thomson, R P Thun, M J Tibbetts, R E Ticse Torres, V O Tikhomirov, Yu A Tikhonov, S Timoshenko, E Tiouchichine, P Tipton, S Tisserant, K Todome, T Todorov, S Todorova-Nova, J Tojo, S Tokár, K Tokushuku, K Tollefson, E Tolley, L Tomlinson, M Tomoto, L Tompkins, K Toms, E Torrence, H Torres, E Torró Pastor, J Toth, F Touchard, D R Tovey, T Trefzger, L Tremblet, A Tricoli, I M Trigger, S Trincaz-Duvoid, M F Tripiana, W Trischuk, B Trocmé, C Troncon, M Trottier-McDonald, M Trovatelli, L Truong, M Trzebinski, A Trzupek, C Tsarouchas, J C-L Tseng, P V Tsiareshka, D Tsionou, G Tsipolitis, N Tsirintanis, S Tsiskaridze, V Tsiskaridze, E G Tskhadadze, I I Tsukerman, V Tsulaia, S Tsuno, D Tsybychev, A Tudorache, V Tudorache, A N Tuna, S A Tupputi, S Turchikhin, D Turecek, R Turra, A J Turvey, P M Tuts, A Tykhonov, M Tylmad, M Tyndel, I Ueda, R Ueno, M Ughetto, M Ugland, F Ukegawa, G Unal, A Undrus, G Unel, F C Ungaro, Y Unno, C Unverdorben, J Urban, P Urquijo, P Urrejola, G Usai, A Usanova, L Vacavant, V Vacek, B Vachon, C Valderanis, N Valencic, S Valentinetti, A Valero, L Valery, S Valkar, S Vallecorsa, J A Valls Ferrer, W Van Den Wollenberg, P C Van Der Deijl, R van der Geer, H van der Graaf, N van Eldik, P van Gemmeren, J Van Nieuwkoop, I van Vulpen, M C van Woerden, M Vanadia, W Vandelli, R Vanguri, A Vaniachine, F Vannucci, G Vardanyan, R Vari, E W Varnes, T Varol, D Varouchas, A Vartapetian, K E Varvell, F Vazeille, T Vazquez Schroeder, J Veatch, L M Veloce, F Veloso, T Velz, S Veneziano, A Ventura, D Ventura, M Venturi, N Venturi, A Venturini, V Vercesi, M Verducci, W Verkerke, J C Vermeulen, A Vest, M C Vetterli, O Viazlo, I Vichou, T Vickey, O E Vickey Boeriu, G H A Viehhauser, S Viel, R Vigne, M Villa, M Villaplana Perez, E Vilucchi, M G Vincter, V B Vinogradov, I Vivarelli, F Vives Vaque, S Vlachos, D Vladoiu, M Vlasak, M Vogel, P Vokac, G Volpi, M Volpi, H von der Schmitt, H von Radziewski, E von Toerne, V Vorobel, K Vorobev, M Vos, R Voss, J H Vossebeld, N Vranjes, M Vranjes Milosavljevic, V Vrba, M Vreeswijk, R Vuillermet, I Vukotic, Z Vykydal, P Wagner, W Wagner, H Wahlberg, S Wahrmund, J Wakabayashi, J Walder, R Walker, W Walkowiak, C Wang, F Wang, H Wang, H Wang, J Wang, J Wang, K Wang, R Wang, S M Wang, T Wang, T Wang, X Wang, C Wanotayaroj, A Warburton, C P Ward, D R Wardrope, A Washbrook, C Wasicki, P M Watkins, A T Watson, I J Watson, M F Watson, G Watts, S Watts, B M Waugh, S Webb, M S Weber, S W Weber, J S Webster, A R Weidberg, B Weinert, J Weingarten, C Weiser, H Weits, P S Wells, T Wenaus, T Wengler, S Wenig, N Wermes, M Werner, P Werner, M Wessels, J Wetter, K Whalen, A M Wharton, A White, M J White, R White, S White, D Whiteson, F J Wickens, W Wiedenmann, M Wielers, P Wienemann, C Wiglesworth, L A M Wiik-Fuchs, A Wildauer, H G Wilkens, H H Williams, S Williams, C Willis, S Willocq, A Wilson, J A Wilson, I Wingerter-Seez, F Winklmeier, B T Winter, M Wittgen, J Wittkowski, S J Wollstadt, M W Wolter, H Wolters, B K Wosiek, J Wotschack, M J Woudstra, K W Wozniak, M Wu, M Wu, S L Wu, X Wu, Y Wu, T R Wyatt, B M Wynne, S Xella, D Xu, L Xu, B Yabsley, S Yacoob, R Yakabe, M Yamada, D Yamaguchi, Y Yamaguchi, A Yamamoto, S Yamamoto, T Yamanaka, K Yamauchi, Y Yamazaki, Z Yan, H Yang, H Yang, Y Yang, W-M Yao, Y C Yap, Y Yasu, E Yatsenko, K H Yau Wong, J Ye, S Ye, I Yeletskikh, A L Yen, E Yildirim, K Yorita, R Yoshida, K Yoshihara, C Young, C J S Young, S Youssef, D R Yu, J Yu, J M Yu, J Yu, L Yuan, S P Y Yuen, A Yurkewicz, I Yusuff, B Zabinski, R Zaidan, A M Zaitsev, J Zalieckas, A Zaman, S Zambito, L Zanello, D Zanzi, C Zeitnitz, M Zeman, A Zemla, Q Zeng, K Zengel, O Zenin, T Ženiš, D Zerwas, D Zhang, F Zhang, G Zhang, H Zhang, J Zhang, L Zhang, R Zhang, X Zhang, Z Zhang, X Zhao, Y Zhao, Z Zhao, A Zhemchugov, J Zhong, B Zhou, C Zhou, L Zhou, L Zhou, M Zhou, N Zhou, C G Zhu, H Zhu, J Zhu, Y Zhu, X Zhuang, K Zhukov, A Zibell, D Zieminska, N I Zimine, C Zimmermann, S Zimmermann, Z Zinonos, M Zinser, M Ziolkowski, L Živković, G Zobernig, A Zoccoli, M Zur Nedden, G Zurzolo, L Zwalinski
This paper reports a detailed study of techniques for identifying boosted, hadronically decaying W bosons using 20.3 fb[Formula: see text] of proton-proton collision data collected by the ATLAS detector at the LHC at a centre-of-mass energy [Formula: see text]. A range of techniques for optimising the signal jet mass resolution are combined with various jet substructure variables. The results of these studies in Monte Carlo simulations show that a simple pairwise combination of groomed jet mass and one substructure variable can provide a 50 % efficiency for identifying W bosons with transverse momenta larger than 200 GeV while maintaining multijet background efficiencies of 2-4 % for jets with the same transverse momentum...
2016: European Physical Journal. C, Particles and Fields
https://www.readbyqxmd.com/read/27471041/solid-pseudopapillary-tumors-of-the-pancreas-specific-pathological-features-predict-the-likelihood-of-postoperative-recurrence
#10
Giovanni Marchegiani, Stefano Andrianello, Marta Massignani, Giuseppe Malleo, Laura Maggino, Salvatore Paiella, Cristina R Ferrone, Claudio Luchini, Aldo Scarpa, Paola Capelli, Mari Mino-Kenudson, Keith D Lillemoe, Claudio Bassi, Carlos Fernàndez-Del Castillo, Roberto Salvia
BACKGROUND: Since their introduction in the WHO classification, the incidence of solid pseudopapillary tumors (SPTs) of the pancreas has progressively increased, mainly because of the widespread use of cross-sectional imaging. Few recent studies have analyzed the biological behavior of SPTs, but reliable data on long-term follow-up are needed. METHODS: Retrospective analysis of two Institutions with high caseload, The Department of General Surgery-Pancreas Institute, University of Verona Hospital Trust and the Department of General Surgery, Massachusetts General Hospital, Harvard Medical School, was carried out...
October 2016: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27322188/does-size-matter-in-pancreatic-cancer-reappraisal-of-tumour-dimension-as-a-predictor-of-outcome-beyond-the-tnm
#11
Giovanni Marchegiani, Stefano Andrianello, Giuseppe Malleo, Lucia De Gregorio, Aldo Scarpa, Mari Mino-Kenudson, Laura Maggino, Cristina R Ferrone, Keith D Lillemoe, Claudio Bassi, Carlos Fernàndez-Del Castillo, Roberto Salvia
OBJECTIVE: To explore the role of pancreatic ductal adenocarcinoma (PDAC) size on surgical and survival outcomes. BACKGROUND: Tumor size is a prognostic factor for the majority of solid cancers, but the role for PDAC in predicting survival is not well delineated affecting the reliability of tumor node metastasis system classification. METHODS: Between 1998 and 2012, 1507 patients with PDAC underwent resection at University of Verona Hospital and the Massachusetts General Hospital...
June 17, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27232260/incorporation-of-procedure-specific-risk-into-the-acs-nsqip-surgical-risk-calculator-improves-the-prediction-of-morbidity-and-mortality-after-pancreatoduodenectomy
#12
Matthew T McMillan, Valentina Allegrini, Horacio J Asbun, Chad G Ball, Claudio Bassi, Joal D Beane, Stephen W Behrman, Adam C Berger, Mark Bloomston, Mark P Callery, John D Christein, Euan Dickson, Elijah Dixon, Jeffrey A Drebin, Carlos Fernandez-Del Castillo, William E Fisher, Zhi Ven Fong, Ericka Haverick, Robert H Hollis, Michael G House, Steven J Hughes, Nigel B Jamieson, Tara S Kent, Stacy J Kowalsky, John W Kunstman, Giuseppe Malleo, Amy L McElhany, Ronald R Salem, Kevin C Soares, Michael H Sprys, Vicente Valero, Ammara A Watkins, Christopher L Wolfgang, Amer H Zureikat, Charles M Vollmer
OBJECTIVE: This multicenter study sought to evaluate the accuracy of the American College of Surgeons National Surgical Quality Improvement Program's (ACS-NSQIP) surgical risk calculator for predicting outcomes after pancreatoduodenectomy (PD) and to determine whether incorporating other factors improves its predictive capacity. BACKGROUND: The ACS-NSQIP surgical risk calculator has been proposed as a decision-support tool to predict complication risk after various operations...
May 26, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27193106/prognostic-factors-for-morbimortality-in-sleeve-gastrectomy-the-importance-of-the-learning-curve-a-spanish-portuguese-multicenter-study
#13
Raquel Sánchez-Santos, Ricard Corcelles Codina, Ramon Vilallonga Puy, Salvadora Delgado Rivilla, Jose Vicente Ferrer Valls, Javier Foncillas Corvinos, Carlos Masdevall Noguera, Maria Socas Macias, Pedro Gomes, Carmen Balague Ponz, Jorge De Tomas Palacios, Sergio Ortiz Sebastian, Andres Sanchez-Pernaute, Jose Julian Puche Pla, Daniel Del Castillo Dejardin, Julen Abasolo Vega, Ester Mans Muntwyler, Ana Garcia Navarro, Carlos Duran Escribano, Norberto Cassinello Fernández, Nieves Perez Climent, Jose Antonio Gracia Solanas, Francisca Garcia-Moreno Nisa, Alberto Hernández Matias, Victor Valentí Azcarate, Jose Eduardo Perez Folques, Inmaculada Navarro Garcia, Eduardo Dominguez-Adame Lanuza, Sagrario Martinez Cortijo, Jesus González Fernández
BACKGROUND: Complications in sleeve gastrectomy (SG) can cast a shadow over the technique's good results and compromise its safety. The aim of this study is to identify risk factors for complications, and especially those that can potentially be modified to improve safety. METHODS: A retrospective multicenter cohort study was carried out, involving the participation of 29 hospitals. Data was collected on demographic variables, associated comorbidities, technical modifications, the surgeon's experience, and postoperative morbimortality...
May 19, 2016: Obesity Surgery
https://www.readbyqxmd.com/read/27169995/regulation-of-gli-underlies-a-role-for-bet-bromodomains-in-pancreatic-cancer-growth-and-the-tumor-microenvironment
#14
Yinshi Huang, Sabikun Nahar, Akifumi Nakagawa, Maite G Fernandez-Barrena, Jennifer A Mertz, Barbara M Bryant, Curtis E Adams, Mari Mino-Kenudson, Kate N Von Alt, Kevin Chang, Andrew R Conery, Charlie Hatton, Robert J Sims, Martin E Fernandez-Zapico, Xingpeng Wang, Keith D Lillemoe, Carlos Fernández-Del Castillo, Andrew L Warshaw, Sarah P Thayer, Andrew S Liss
PURPOSE: The initiation, progression, and maintenance of pancreatic ductal adenocarcinoma (PDAC) results from the interplay of genetic and epigenetic events. While the genetic alterations of PDAC have been well characterized, epigenetic pathways regulating PDAC remain, for the most part, elusive. The goal of this study was to identify novel epigenetic regulators contributing to the biology of PDAC. EXPERIMENTAL DESIGN: In vivo pooled shRNA screens targeting 118 epigenetic proteins were performed in two orthotopic PDAC xenograft models...
August 15, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/27163957/multi-institutional-validation-study-of-the-american-joint-commission-on-cancer-8th-edition-changes-for-t-and-n-staging-in-patients-with-pancreatic-adenocarcinoma
#15
Peter J Allen, Deborah Kuk, Carlos Fernandez-Del Castillo, Olca Basturk, Christopher L Wolfgang, John L Cameron, Keith D Lillemoe, Cristina R Ferrone, Vicente Morales-Oyarvide, Jin He, Matthew J Weiss, Ralph H Hruban, Mithat Gönen, David S Klimstra, Mari Mino-Kenudson
OBJECTIVE: The aim of this study was to evaluate and validate the proposed 8th edition American Joint Committee on Cancer (AJCC) system for T and N staging of pancreatic adenocarcinoma. SUMMARY OF BACKGROUND DATA: Investigators have questioned the clinical relevance and reproducibility of previous AJCC staging for pancreatic adenocarcinoma. METHODS: Prospective databases at Memorial Sloan Kettering (MSK), Massachusetts General Hospital (MGH), and Johns Hopkins Hospital (JHH) were queried for patients who had undergone resection for pancreatic adenocarcinoma...
May 9, 2016: Annals of Surgery
https://www.readbyqxmd.com/read/27092317/the-value-of-kras-mutation-testing-with-cea-for-the-diagnosis-of-pancreatic-mucinous-cysts
#16
Abdurrahman Kadayifci, Mohammad Al-Haddad, Mustafa Atar, John M Dewitt, David G Forcione, Stuart Sherman, Brenna W Casey, Carlos Fernandez-Del Castillo, C Max Schmidt, Martha B Pitman, William R Brugge
BACKGROUND AND AIMS: Pancreatic cyst fluid (PCF) CEA has been shown to be the most accurate preoperative test for detection of cystic mucinous neoplasms (CMNs). This study aimed to assess the added value of PCF KRAS mutational analysis to CEA for diagnosis of CMNs. PATIENTS AND METHODS: This is a retrospective study of prospectively collected endoscopic ultrasonography (EUS) fine-needle aspiration (FNA) data. KRAS mutation was determined by direct sequencing or equivalent methods...
April 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27020585/phosphorylated-histone-h3-phh3-is-a-superior-proliferation-marker-for-prognosis-of-pancreatic-neuroendocrine-tumors
#17
Vincenzo Villani, Krishnan K Mahadevan, Matteo Ligorio, Carlos Fernández-Del Castillo, David T Ting, Francesco Sabbatino, Irene Zhang, Mark Vangel, Soldano Ferrone, Andrew L Warshaw, Keith D Lillemoe, Jennifer Wargo, Vikram Deshpande, Cristina R Ferrone
BACKGROUND: The staging of pancreatic neuroendocrine tumors (PNETs) is continuously evolving. Mitotic count, as measured by hematoxylin and eosin (H&E) or Ki67 labeling index (Ki67LI), is the best predictor of disease biology. However, both of these methods have several limitations. Phosphorylated histone H3 (PHH3), a novel mitotic marker, is potentially more accurate and easier to evaluate. This study aimed to evaluate the prognostic impact of PHH3 on patients with PNETs. METHODS: Clinicopathologic data and paraffin-embedded tissue were evaluated for 100 of the 247 PNET patients whose tumors were resected between 1998 and 2010...
March 28, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/26965783/risk-of-pancreatic-malignancy-and-mortality-in-branch-duct-ipmns-undergoing-surveillance-a-systematic-review-and-meta-analysis
#18
REVIEW
Stefano Crippa, Gabriele Capurso, Calogero Cammà, Gianfranco Delle Fave, Carlos Fernández-Del Castillo, Massimo Falconi
BACKGROUND: Safety of non-operative management for low-risk branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) is debated. AIM: To perform a systematic review/meta-analysis to determine their risk of developing pancreatic malignancy and of pancreatic malignancy-related deaths. METHODS: A MEDLINE search was performed and methodology was based on PRISMA statement. Incidence rates of overall pancreatic malignancy, malignant BD-IPMN, IPMN-distinct PDAC, and of pancreatic malignancy-related death rates were calculated by dividing the total number of events by the total number of person-years (pyrs) of follow-up...
May 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/26956004/intra-pancreatic-distal-bile-duct-carcinoma-is-morphologically-genetically-and-clinically-distinct-from-pancreatic-ductal-adenocarcinoma
#19
Vikram Deshpande, Ioannis T Konstantinidis, Carlos Fernandez-Del Castillo, Aram F Hezel, Kevin M Haigis, David T Ting, Nabeel Bardeesy, Lipika Goyal, Andrew X Zhu, Andrew L Warshaw, Keith D Lillemoe, Cristina R Ferrone
PURPOSE: Differentiating intra-pancreatic distal bile duct carcinoma invading the pancreas from pancreatic ductal adenocarcinomas (PDAC) surrounding the distal common bile duct (CBD) can be challenging. Our aim is to identify clinical, morphological, and genetic features characteristic of intra-pancreatic distal bile duct carcinoma. METHODS: Clinicopathologic data of 550 patients undergoing a pancreaticoduodenectomy between September 1990 and May 2008 were reviewed...
May 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/26954894/early-drain-amylase-value-predicts-the-occurrence-of-pancreatic-fistula-after-pancreaticoduodenectomy
#20
Zhi Ven Fong, Carlos Fernández-Del Castillo
No abstract text is available yet for this article.
March 7, 2016: Annals of Surgery
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