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https://www.readbyqxmd.com/read/29915644/right-ventricular-dysplasia-management-and-treatment-in-light-of-current-evidence
#1
REVIEW
Amr Idris, Syed Raza Shah, Ki Park
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare cardiovascular disease that predisposes to ventricular arrhythmias potentially leading to sudden cardiac death (SCD). ARVC varies considerably with multiple clinical presentations, ranging from no symptoms to cardiac arrhythmias to SCD. ARVC prevalence is not well known, but the estimated prevalence in the general population is 1:5000. Diagnosis of ARVC can be made by using the Revised European Society of Cardiology criteria for ARVC that includes ventricular structural and functional changes, ECG abnormalities, arrhythmias, family and genetic factors...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29915636/-enterococcus-faecalis-infective-endocarditis-and-colorectal-carcinoma-case-of-new-association-gaining-ground
#2
Zubair Khan, Nauman Siddiqui, Muhammad Wasif Saif
Mostly Streptococcus bovis ( S. bovis ) bacteremia and endocarditis (60%) has been found to be associated with underlying colorectal cancer (CRC). Enterococcus faecalis ( E. faecalis ) bacteremia and endocarditis has no identifiable source in most of the cases. E. faecalis is part of normal gut flora that can translocate through the intestine and cause the systemic infection. With any intestinal lesion or tumor, the barrier is breached and the gut flora like E. faecalis can translocate and cause infection. A 55-years-old male known to have non-ischemic cardiomyopathy with implantation of automated implantable cardioverter defibrillator (AICD) and atrial fibrillation presented with weight loss, fever and back pain...
June 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29912348/heat-induced-oxidation-of-an-implantable-cardioverter-defibrillator-titanium-alloy-housing
#3
Marc-Alexander Ohlow, J Christoph Geller
No abstract text is available yet for this article.
April 17, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29910581/physicians-knowledge-and-attitudes-in-saudi-arabia-regarding-implantable-cardiac-defibrillators
#4
Tariq Alhogbani, Fuad A Awwad, Abdullah S Aljasser
Objectives: To evaluate knowledge and attitude of physicians involved in the management of patients with heart failure regarding implantable cardioverter-defibrillator (ICD). Methods: We conducted personal interviews with physicians involved in treating patients with heart failure. Between October 2015 and February 2016, the study was conducted in hospitals in the Riyadh region where no cardiac electrophysiology service was available. Every participant was met in person and received an oral questionnaire that aimed to assess basic knowledge regarding ICD indications and benefits...
April 2018: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/29910051/the-relationship-between-baseline-and-follow-up-left-ventricular-ejection-fraction-with-adverse-events-among-primary-prevention-icd-patients
#5
Daniel J Friedman, Marat Fudim, Robert Overton, Linda K Shaw, Divyang Patel, Sean D Pokorney, Eric J Velazquez, Sana M Al-Khatib
BACKGROUND: Left ventricular ejection fraction (LVEF) is used to select patients for primary prevention implantable cardioverter defibrillators (ICDs). The relationship between baseline and long-term follow-up LVEF and clinical outcomes among primary prevention ICD patients remains unclear. METHODS: We studied 195 patients with a baseline LVEF ≤35% ≤6 months prior to ICD implantation and follow-up LVEF 1-3 years after ICD implantation without intervening left ventricular assist device (LVAD) or transplant...
July 2018: American Heart Journal
https://www.readbyqxmd.com/read/29909402/impact-of-exercise-restriction-on-arrhythmic-risk-among-patients-with-arrhythmogenic-right-ventricular-cardiomyopathy
#6
Weijia Wang, Gabriela Orgeron, Crystal Tichnell, Brittney Murray, Jane Crosson, Oliver Monfredi, Julia Cadrin-Tourigny, Harikrishna Tandri, Hugh Calkins, Cynthia A James
BACKGROUND: Prior studies have shown a close link between exercise and development of arrhythmogenic right ventricular cardiomyopathy. How much exercise restriction reduces ventricular arrhythmia (VA), how genotype modifies its benefit, and whether it reduces risk sufficiently to defer implantable cardioverter-defibrillator (ICD) placement in arrhythmogenic right ventricular cardiomyopathy are unknown. METHODS AND RESULTS: We interviewed 129 arrhythmogenic right ventricular cardiomyopathy patients (age: 34...
June 16, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29909164/-is-it-possible-to-practice-sports-with-an-implantable-cardioverter-defibrillator
#7
Charles Guenancia, Rodrigue Garcia
Why? The potential risks of sport for an ICD recipient include appropriate and inappropriate shocks, device damage and worsening of the underlying cardiopathy. These risks should be compared to the physical and psychological benefits of exercise. Where? Due to different medico-legal contexts and considering the results of recent studies, the new US guidelines are more permissive than the European guidelines regarding sport practice in ICD recipients. Who? The underlying context (structural or electrical cardiopathy, psychological impact) should be assessed before any decision is taken...
June 13, 2018: La Presse Médicale
https://www.readbyqxmd.com/read/29907873/genetic-background-of-japanese-patients-with-pediatric-hypertrophic-and-restrictive-cardiomyopathy
#8
Takeharu Hayashi, Kousuke Tanimoto, Kayoko Hirayama-Yamada, Etsuko Tsuda, Mamoru Ayusawa, Shinichi Nunoda, Akira Hosaki, Akinori Kimura
Hypertrophic cardiomyopathy (HCM) and restrictive cardiomyopathy (RCM) present a high risk for sudden cardiac death in pediatric patients. The aim of this study was to identify disease-associated genetic variants in Japanese patients with pediatric HCM and RCM. We analyzed 67 cardiomyopathy-associated genes in 46 HCM and 7 RCM patients diagnosed before 16 years of age using a next-generation sequencing system. We found that 78% of HCM and 71% of RCM patients carried disease-associated genetic variants. Disease-associated genetic variants were identified in 80% of HCM patients with a family history and in 77% of HCM patients with no apparent family history (NFH)...
June 15, 2018: Journal of Human Genetics
https://www.readbyqxmd.com/read/29907652/cardiac-resynchronization-therapy-and-clinical-outcomes-in-continuous-flow-left-ventricular-assist-device-recipients
#9
Rakesh Gopinathannair, Henri Roukoz, Adarsh Bhan, Ashwin Ravichandran, Mustafa M Ahmed, Dmitry Familtsev, Geetha Bhat, Jennifer Cowger, Munazzah Abdullah, Chirag Sandesara, Rahul Dhawan, Emma J Birks, Jaimin R Trivedi, Mark S Slaughter
BACKGROUND: Many patients with heart failure continue cardiac resynchronization therapy (CRT) after continuous flow left ventricular assist device (CF-LVAD) implant. We report the first multicenter study to assess the impact of CRT on clinical outcomes in CF-LVAD patients. METHODS AND RESULTS: Analysis was performed on 488 patients (58±13 years, 81% male) with an implantable cardioverter defibrillator (ICD) (n=223) or CRT-D (n=265) who underwent CF-LVAD implantation at 5 centers from 2007 to 2015...
June 15, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29907466/sudden-death-risk-markers-for-patients-with-left-ventricular-ejection-fractions-greater-than-40
#10
REVIEW
Brian P Halliday, Amrit S Lota, Sanjay K Prasad
The major burden of sudden cardiac death (SCD) in patients with heart disease occurs in those with a left ventricular ejection fraction > 40%. Although the annual risk of SCD may be lower in these patients compared to those with lower LVEF, their lifetime cumulative risk of SCD may be greater due to a better overall prognosis. It is plausible that those with LVEF > 40% who are at highest risk of life-threatening arrhythmia will benefit from implantable cardioverter defibrillators. Features that identify patients with a LVEF > 40% at high risk of SCD are urgently needed...
June 12, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29905810/the-time-is-not-ripe-for-the-wearable-cardioverter-defibrillator
#11
Jens Cosedis Nielsen, Jens Brock Johansen
No abstract text is available yet for this article.
June 14, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29905788/extended-use-of-the-wearable-cardioverter-defibrillator-in-patients-at-risk-for-sudden-cardiac-death
#12
Valentina Kutyifa, Katherine Vermilye, Usama A Daimee, Scott McNitt, Helmut Klein, Arthur J Moss
Aims: Data on outcomes in patients using the wearable cardioverter-defibrillator (WCD) > 90 days are limited. We aimed to analyse the clinical course of patients with WCD use ≤90 days vs. WCD use >90 days. Methods and results: We assessed arrhythmia events during WCD use, and ejection fraction (EF) improvement/implantable cardioverter-defibrillator (ICD) implantation at the end of WCD use in patients with WCD use ≤90 days vs. WCD use >90 days enrolled in the WEARIT-II registry, further assessed by disease aetiology (ischaemic vs...
June 14, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29905373/leadless-pacemaker-and-subcutaneous-implantable-cardioverter-defibrillator-therapy-the-first-use-of-a-novel-treatment-option-in-poland
#13
Krzysztof Kaczmarek, Bartosz Czarniak, Piotr Jakubowski, Jerzy K Wranicz, Paweł Ptaszyński
No abstract text is available yet for this article.
2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29899727/flecainide-induced-brugada-syndrome-in-a-patient-with-skeletal-muscle-sodium-channelopathy-a-case-report-with-critical-therapeutical-implications-and-review-of-the-literature
#14
Michele Cavalli, Barbara Fossati, Raffaele Vitale, Elisa Brigonzi, Vito A G Ricigliano, Lorenzo Saraceno, Rosanna Cardani, Carlo Pappone, Giovanni Meola
Skeletal muscle sodium channelopathies are a group of neuromuscular disorders associated with mutations in the SCN4A gene. Because principal sodium channel isoforms expressed in the skeletal muscles and the heart are distinct one from the other, this condition usually spares cardiac functioning. Nonetheless, evidence on a possible link between skeletal muscle and cardiac sodium channelopathies has emerged in recent years. To date, eight patients bearing pathogenetic mutations in the SCN4A gene and manifesting cardiac electrophysiological alterations have been reported in literature...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29898017/cohort-of-patients-referred-for-brugada-syndrome-investigation-in-an-electrophysiology-service-19-year-registry
#15
Stefan Warpechowski Neto, Tiago Luiz Luz Leiria, Laura Lessa Gaudie Ley, Antonio Lessa Gaudie Ley, Luiza Zwan Dutra, Leonardo Martins Pires, Marcelo Lapa Kruse, Gustavo Glotz de Lima
BACKGROUND: Brugada syndrome (SBr) is an arrhythmic condition characterized by ST-T segment abnormalities in the right precordial leads associated with a high risk of ventricular arrhythmias and sudden death. Local data regarding the clinical characteristics of patients with a typical electrocardiographic (ECG) pattern undergoing electrophysiological study are scarce. OBJECTIVE: To evaluate patients with an ECG pattern suggestive of SBr referred for electrophysiological evaluation in a specialized center...
June 11, 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29897106/clinical-parameters-to-optimize-patient-selection-for-subcutaneous-and-transvenous-implantable-defibrillator-therapy
#16
Anne-Floor B E Quast, Tom F Brouwer, Fleur V Y Tjong, Arthur A M Wilde, Reinoud E Knops
BACKGROUND: The subcutaneous implantable cardioverter-defibrillator (S-ICD) lacks the antitachycardia pacing (ATP) capability of tranvenous ICDs (TV-ICD). S-ICD patient selection can be challenging as some patients may benefit from ATP. We aim to identify clinical predictors of ATP benefit, in order to improve patient selection for S-ICD or TV-ICD therapy. METHODS: De novo single- and dual-chamber TV-ICD patients implanted between March 2011 and December 2015 were included...
June 13, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29896873/quantifying-the-utilization-of-medical-devices-necessary-to-detect-postmarket-safety-differences-a-case-study-of-implantable-cardioverter-defibrillators
#17
Jonathan Bates, Craig S Parzynski, Sanket S Dhruva, Andreas Coppi, Richard Kuntz, Shu-Xia Li, Danica Marinac-Dabic, Frederick A Masoudi, Richard E Shaw, Frederick Warner, Harlan M Krumholz, Joseph S Ross
PURPOSE: To estimate medical device utilization needed to detect safety differences among implantable cardioverter defibrillators (ICDs) generator models and compare these estimates to utilization in practice. METHODS: We conducted repeated sample size estimates to calculate the medical device utilization needed, systematically varying device-specific safety event rate ratios and significance levels while maintaining 80% power, testing 3 average adverse event rates (3...
June 12, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29894674/-calculator-available-prognosis-method-of-evaluation-for-predicting-survival-of-patients-with-chronic-heart-failure-and-reduced-left-ventricular-ejection-fraction
#18
L V Prokopova, M Y Sitnikova
BACKGROUND: A method for predicting one-year survival of patients with heart failure and reduced ejection fraction (HFrEF) is required to choose a management tactics and determine indications for high-tech care at the outpatient stage. AIM: To develop a method for proper prediction of survival of patients with HFrEF in outpatient clinics. MATERIALS AND METHODS: This was a prospective study of 212 patients with functional class II-IV CHF of non-valvular origin and LV EF (Simpson) ≤35 % aged 18-70, including 176 (83 %) men and 36 (17 %) women who had given an informed consent to participate in the study...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29894002/analysis-of-early-failure-of-biotronik-linox-smart-implantable-cardioverter-defibrillator-leads-a-comparative-study-of-three-defibrillator-leads
#19
Diego Pérez Díez, José Manuel Rubín, David Calvo Cuervo, Daniel García Iglesias, César Morís De La Tassa
BACKGROUND AND OBJECTIVES: Early failure of Biotronik Linox and Linox Smart leads has been reported in numerous recent publications. The aim of this study was to assess the performance of this lead compared with that of 2 other contemporary leads. METHODS: We conducted an ambispective study of all consecutive first implantations of defibrillator leads carried out in our center: Endotak (Boston Scientific, model 148, 158)(n = 173), Sprint Quattro (Medtronic, model 6644, 6947)(n = 145) and Linox Smart (Biotronik, model SD 65/16)(n = 120)...
June 12, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29893508/effect-of-defibrillation-threshold-testing-on-effectiveness-of-the-subcutaneous-implantable-cardioverter-defibrillator
#20
Lakshmi Peddareddy, Faisal M Merchant, Angel R Leon, Paige Smith, Akshar Patel, Mikhael F El-Chami
BACKGROUND: Defibrillation threshold (DFT) testing is recommended with the subcutaneous ICD (SICD). OBJECTIVE: To describe first shock efficacy for appropriate SICD therapies stratified by the presence of implant DFT testing. METHODS: We reviewed all patients receiving SICDs at our institution and stratified them based on whether implant DFT testing was performed. Appropriate shocks were reviewed to see if ventricular tachycardia/ventricular fibrillation (VT/VF) terminated with a single shock...
June 12, 2018: Pacing and Clinical Electrophysiology: PACE
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