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https://www.readbyqxmd.com/read/29207243/significantly-enhanced-dielectric-performances-and-high-thermal-conductivity-in-poly-vinylidene-fluoride-based-composites-enabled-by-sic-sio2-core-shell-whiskers-alignment
#1
Dalong He, Yao Wang, Silong Song, Song Liu, Yuan Deng
Design of composites with ordered fillers arrangement results in anisotropic performances with greatly enhanced properties along specific direction, which is a powerful tool to optimize physical properties of composites. Well aligned core-shell SiC@SiO2 whiskers in poly(vinylidene fluoride) (PVDF) matrix has been achieved via a modified spinning approach. Due to high aspect ratio of SiC whiskers, strong anisotropy and significant enhancement in dielectric constant were observed with permittivity 854 along parallel direction vs...
December 5, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29194600/first-record-of-non-native-hybrid-catfish-pseudoplatystoma-reticulatum%C3%A2-%C3%A3-%C3%A2-leiarius-marmoratus-in-the-upper-paran%C3%A3-river-basin-brazil
#2
M H S Yabu, A P Vidotto-Magnoni, A C R Casimiro, D A Z Garcia, A D A Costa, F D D Prado, F Porto-Foresti, M L Orsi
The aim of this study is to report the presence of a three non-native hybrid long-whiskered catfishes (family Pimelodidae) in the Upper Paraná River basin, Brazil. Genetic analyses demonstrated that the three presumptive hybrids were a result of the crossbreeding of Pseudoplatystoma reticulatum (central Amazonas River basin and Lower Paraná River) and Leiarius marmoratus (Amazonas, Essequibo and Orinoco rivers), producing a hybrid commonly known in Brazil as cachandiá. The potential threat to biodiversity, due to possible genetic contamination, competition and predation of wild stocks, of such artificially produced hybrid fishes is discussed...
November 30, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/29184204/weak-correlations-between-hemodynamic-signals-and-ongoing-neural-activity-during-the-resting-state
#3
Aaron T Winder, Christina Echagarruga, Qingguang Zhang, Patrick J Drew
Spontaneous fluctuations in hemodynamic signals in the absence of a task or overt stimulation are used to infer neural activity. We tested this coupling by simultaneously measuring neural activity and changes in cerebral blood volume (CBV) in the somatosensory cortex of awake, head-fixed mice during periods of true rest and during whisker stimulation and volitional whisking. We found that neurovascular coupling was similar across states and that large, spontaneous CBV changes in the absence of sensory input were driven by volitional whisker and body movements...
December 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/29183683/cellular-diversity-of-the-somatosensory-cortical-map-plasticity
#4
REVIEW
Koen Kole, Wim Scheenen, Paul Tiesinga, Tansu Celikel
Sensory maps are representations of the sensory epithelia in the brain. Despite the intuitive explanatory power behind sensory maps as being neuronal precursors to sensory perception, and sensory cortical plasticity as a neural correlate of perceptual learning, molecular mechanisms that regulate map plasticity are not well understood. Here we perform a meta-analysis of transcriptional and translational changes during altered whisker use to nominate the major molecular correlates of experience-dependent map plasticity in the barrel cortex...
November 25, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29170270/the-role-of-hemodynamics-in-intracranial-bifurcation-arteries-after-aneurysm-treatment-with-flow-diverter-stents
#5
A P Narata, F S de Moura, I Larrabide, C M Perrault, F Patat, R Bibi, S Velasco, A-C Januel, C Cognard, R Chapot, A Bouakaz, C A Sennoga, A Marzo
BACKGROUND AND PURPOSE: Treatment of intracranial bifurcation aneurysms with flow-diverter stents can lead to caliber changes of the distal vessels in a subacute phase. This study aims to evaluate whether local anatomy and flow disruption induced by flow-diverter stents are associated with vessel caliber changes in intracranial bifurcations. MATERIALS AND METHODS: Radiologic images and demographic data were acquired for 25 patients with bifurcation aneurysms treated with flow-diverter stents...
November 23, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29165394/wxc-%C3%AE-sic-nanocomposite-catalysts-used-in-aqueous-phase-hydrogenation-of-furfural
#6
Jacek Rogowski, Mariusz Andrzejczuk, Joanna Berlowska, Michal Binczarski, Dorota Kregiel, Andrzej Kubiak, Magdalena Modelska, Elzbieta Szubiakiewicz, Andrei Stanishevsky, Jolanta Tomaszewska, Izabela Alina Witonska
This study investigates the effects of the addition of tungsten on the structure, phase composition, textural properties and activities of β-SiC-based catalysts in the aqueous phase hydrogenation of furfural. Carbothermal reduction of SiO₂ in the presence of WO₃ at 1550 °C in argon resulted in the formation of WxC-β-SiC nanocomposite powders with significant variations in particle morphology and content of WxC-tipped β-SiC nano-whiskers, as revealed by TEM and SEM-EDS. The specific surface area (SSA) of the nanocomposite strongly depended on the amount of tungsten and had a notable impact on its catalytic properties for the production of furfuryl alcohol (FA) and tetrahydrofurfuryl alcohol (THFA)...
November 22, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29158108/signaling-by-synaptic-zinc-is-required-for-whisker-mediated-fine-texture-discrimination
#7
Hsia-Pai Patrick Wu, Richard H Dyck
Zinc-containing terminals are found throughout the neocortex, concentrated predominantly in layers II/III, V, and VI. Synaptic zinc is a potent neurotransmitter/modulator and, therefore, may mediate inter- or intra-cortical integration of sensory information. We have previously shown that levels of synaptic zinc are rapidly modulated in somatosensory (barrel) cortex, in an experience- and activity-dependent manner. Zinc Transporter 3 (ZnT3) knockout (KO) mice lack synaptic zinc and provide us with a good model to examine the contribution of synaptic zinc to barrel cortex-dependent behavior...
November 17, 2017: Neuroscience
https://www.readbyqxmd.com/read/29157017/comprehensive-assessment-of-shockwave-intensity-transcriptomic-biomarker-discovery-for-primary-blast-induced-mild-traumatic-brain-injury-using-the-mammalian-hair-follicle
#8
Jing Zhang, Rosalinda Knight, Yushan Wang, Thomas W Sawyer, Christopher J Martyniuk, Valerie S Langlois
OBJECTIVE: Primary blast-induced mild traumatic brain injury (mTBI) is an injury experienced during modern warfare due to exposure to the pressure waves produced by the detonation of explosives. With virtually no apparent physical damage or symptoms presented, there is a need for more objective and accessible mTBI biomarkers posing minimal invasiveness risk. METHODS: We measured the transcriptomic sensitivity of the hair follicles in relation to the severity of primary blast-derived TBI...
November 20, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29138622/antimicrobial-efficacy-of-penicillium-amestolkiae-elv609-extract-treated-cotton-fabric-for-diabetic-wound-care
#9
Nur Amiera Syuhada Binti Rozman, Nurhanis Syafiqah Binti Mohd Nor Hamin, Leong Chean Ring, Tan Wen Nee, Mahfuzah Binti Mustapha, Tong Woei Yenn
Diabetes mellitus is a chronic disorder which affects millions of population worldwide. Global estimates published in 2010 reported the world diabetic prevalence as 6.4%, affecting 285 million adults. Foot ulceration and wound infection are major forms of disabilities arising from diabetic diseases. This study was aimed to develop a natural antimicrobial finishing on medical grade textile that meets American Association of Textiles Chemists and Colorists (AATCC) standard. The textile samples were finished with the ethanolic extract of Penicillium amestolkiae elv609, an endophytic fungus isolated from Orthosiphon stamineus Benth (common name: cat's whiskers)...
September 2017: Mycobiology
https://www.readbyqxmd.com/read/29134730/role-of-central-versus-peripheral-opioid-system-in-antinociceptive-and-anti-inflammatory-effect-of-botulinum-toxin-type-a-in-trigeminal-region
#10
V Drinovac Vlah, B Filipović, L Bach-Rojecky, Z Lacković
BACKGROUND: Although botulinum toxin type A (BT-A) is approved for chronic migraine treatment, its site and mechanism of action are still elusive. Recently our group discovered that suppression of CGRP release from dural nerve endings might account for antimigraine action of pericranially injected BT-A. We demonstrated that central antinociceptive effect of BT-A in sciatic region involves endogenous opioid system as well. Here we investigated possible interaction of BT-A with endogenous opioid system within the trigeminal region...
November 13, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29131858/the-composition-and-initial-evaluation-of-a-grimace-scale-in-ferrets-after-surgical-implantation-of-a-telemetry-probe
#11
Marsinah L Reijgwart, Nico J Schoemaker, Riccardo Pascuzzo, Matthew C Leach, Melanie Stodel, Loes de Nies, Coenraad F M Hendriksen, Miriam van der Meer, Claudia M Vinke, Yvonne R A van Zeeland
Reliable recognition of pain is difficult in ferrets as many currently available parameters are non-specific, inconsistent and/or impractical. Grimace scales have successfully been applied to assess pain in different animal species and might also be applicable to ferrets. To compose a Ferret Grimace Scale (FGS), we studied the facial musculature of ferrets and compared lateral photographs of 19 ferret faces at six time points before and after intraperitoneal telemetry probe implantation. We identified the Action Units (AUs) orbital tightening, nose bulging, cheek bulging, ear changes and whisker retraction as potential indicators of pain in ferrets...
2017: PloS One
https://www.readbyqxmd.com/read/29128628/optogenetic-noise-photostimulation-on-the-brain-increases-somatosensory-spike-firing-responses
#12
Nayeli Huidobro, Braniff De la Torre-Valdovinos, Abraham Mendez, Mario Treviño, Oscar Arias-Carrion, Fermin Chavez, Ranier Gutierrez, Elias Manjarrez
We examined whether the optogenetic noise-photostimulation (ONP) of the barrel cortex (BC) of anesthetized Thy1-ChR2-YFP transgenic mice increases the neuronal multiunit-activity response evoked by whisker mechanical stimulation (whisker-evoked MUA). In all transgenic mice, we found that the signal-to-noise ratio (SNR) of such whisker-evoked MUA signals exhibited an inverted U-like shape as a function of the ONP level. Numerical simulations of a ChR2-expressing neuron model qualitatively support our experimental data...
November 9, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29122591/spiking-and-excitatory-inhibitory-input-dynamics-of-barrel-cells-in-response-to-whisker-deflections-of-varying-velocity-and-angular-direction
#13
Mainak Patel
The spiking of barrel regular-spiking (RS) cells is tuned for both whisker deflection direction and velocity. Velocity tuning arises due to thalamocortical (TC) synchrony (but not spike quantity) varying with deflection velocity, coupled with feedforward inhibition, while direction selectivity is not fully understood, though may be due partly to direction tuning of TC spiking. Data show that as deflection direction deviates from the preferred direction of an RS cell, excitatory input to the RS cell diminishes minimally, but temporally shifts to coincide with the time-lagged inhibitory input...
November 6, 2017: Neuroscience
https://www.readbyqxmd.com/read/29121184/barrel-cortical-neuron-integrates-triple-associated-signals-for-their-memory-through-receiving-epigenetic-mediated-new-synapse-innervations
#14
Jing Feng, Wei Lu, Dangui Wang, Ke Ma, Zhenhua Song, Na Chen, Yan Sun, Kaixin Du, Mengmeng Shen, Shan Cui, Jin-Hui Wang
Associative learning is common way for information acquisition. Associative memory is essential to logical reasoning and associative thinking. The storages of multiple associated signals in individual neurons facilitate their integration, expand memory volume, and strengthen cognition ability. Associative memory cells that encode multiple signals have been reported, however, the mechanisms underlying their recruitment and working principle remain to be addressed. We have examined the recruitment of associative memory cells that integrate and store triple sensory signals as well as the potential mechanism of their recruitment...
December 1, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29118695/synapse-innervation-and-associative-memory-cell-are-recruited-for-integrative-storage-of-whisker-and-odor-signals-in-the-barrel-cortex-through-mirna-mediated-processes
#15
Zhuofan Lei, Dangui Wang, Na Chen, Ke Ma, Wei Lu, Zhenhua Song, Shan Cui, Jin-Hui Wang
Associative learning is a common way for information acquisition, and the integrative storage of multiple associated signals is essential for associative thinking and logical reasoning. In terms of the cellular mechanism for associative memory, our studies by behavioral task and cellular imaging demonstrate that paired whisker and odor stimulations lead to odorant-induced whisker motion and associative memory cell recruitment in the barrel cortex (BC), which is driven presumably by synapse innervation from co-activated sensory cortices...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29116263/magnetic-sulfur-doped-porous-carbon-for-preconcentration-of-trace-mercury-in-environmental-water-prior-to-icp-ms-detection
#16
Chuyu Peng, Man He, Beibei Chen, Lijin Huang, Bin Hu
A novel magnetic sulfur-doped porous carbon (MSPC) was fabricated via a simple one-step carbonization of a mixture of sucrose, basic magnesium sulfate whiskers and Fe3O4@SiO2 nanoparticles. Due to the high S content, the prepared MSPC possessed high adsorption capacity for Hg(2+) (343 mg g(-1)) with good selectivity. Based on this, a method coupling magnetic solid phase extraction (MSPE) with inductively coupled plasma mass spectrometry (ICP-MS) was developed for the determination of trace Hg(2+) in environmental water samples...
November 8, 2017: Analyst
https://www.readbyqxmd.com/read/29106499/autism-related-neuroligin-4-knockout-impairs-intracortical-processing-but-not-sensory-inputs-in-mouse-barrel-cortex
#17
Petr Unichenko, Jenq-Wei Yang, Sergei Kirischuk, Sergei Kolbaev, Werner Kilb, Matthieu Hammer, Dilja Krueger-Burg, Nils Brose, Heiko J Luhmann
Neuroligin-4 (Nlgn4) is a cell adhesion protein that regulates synapse organization and function. Mutations in human NLGN4 are among the causes of autism spectrum disorders. In mouse, Nlgn4 knockout (KO) perturbs GABAergic synaptic transmission and oscillatory activity in hippocampus, and causes social interaction deficits. The complex profile of cellular and circuit changes that are caused by Nlgn4-KO is still only partly understood. Using Nlgn4-KO mice, we found that Nlgn4-KO increases the power in the alpha frequency band of spontaneous network activity in the barrel cortex under urethane anesthesia in vivo...
July 5, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29089872/role-for-the-ventral-posterior-medial-posterior-lateral-thalamus-and-anterior-cingulate-cortex-in-affective-motivation-pain-induced-by-varicella-zoster-virus
#18
Phillip R Kramer, Jennifer Strand, Crystal Stinson, Larry L Bellinger, Paul R Kinchington, Michael B Yee, Mikhail Umorin, Yuan B Peng
Varicella zoster virus (VZV) infects the face and can result in chronic, debilitating pain. The mechanism for this pain is unknown and current treatment is often not effective, thus investigations into the pain pathway become vital. Pain itself is multidimensional, consisting of sensory and affective experiences. One of the primary brain substrates for transmitting sensory signals in the face is the ventral posterior medial/posterior lateral thalamus (VPM/VPL). In addition, the anterior cingulate cortex (ACC) has been shown to be vital in the affective experience of pain, so investigating both of these areas in freely behaving animals was completed to address the role of the brain in VZV-induced pain...
2017: Frontiers in Integrative Neuroscience
https://www.readbyqxmd.com/read/29070702/optimization-of-experimental-parameters-in-data-independent-mass-spectrometry-significantly-increases-depth-and-reproducibility-of-results
#19
Roland Bruderer, Oliver M Bernhardt, Tejas Gandhi, Yue Xuan, Julia Sondermann, Manuela Schmidt, David Gomez-Varela, Lukas Reiter
Comprehensive, reproducible and precise analysis of large sample cohorts is one of the key objectives of quantitative proteomics. Here, we present an implementation of data-independent acquisition using its parallel acquisition nature that surpasses the limitation of serial MS2 acquisition of data-dependent acquisition on a quadrupole ultra-high field Orbitrap mass spectrometer. In deep single shot data-independent acquisition, we identified and quantified 6,383 proteins in human cell lines using 2-or-more peptides/protein and over 7,100 proteins when including the 717 proteins that were identified on the basis of a single peptide sequence...
October 25, 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/29069599/volume-conduction-coupling-of-whisker-evoked-cortical-lfp-in-the-mouse-olfactory-bulb
#20
Ana Parabucki, Ilan Lampl
Local field potentials (LFPs) are an important measure of brain activity and have been used to address various mechanistic and behavioral questions. We revealed a prominent whisker-evoked LFP signal in the olfactory bulb and investigated its physiology. This signal, dependent on barrel cortex activation and highly correlated with its local activity, represented a pure volume conduction signal that was sourced back to the activity in the ventro-lateral orbitofrontal cortex, located a few millimeters away. Thus, we suggest that special care should be taken when acquiring and interpreting LFP data...
October 24, 2017: Cell Reports
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