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https://www.readbyqxmd.com/read/28608156/a-study-on-the-oil-based-drilling-cutting-pyrolysis-residue-resource-utilization-by-the-exploration-and-development-of-shale-gas
#1
Chao-Qiang Wang, Ji-Zhong Jin, Xiao-Yan Lin, De-Ming Xiong, Xu-Dong Mei
Based on the requirement of national energy conservation and environmental protection, attention has been given to building an environment-friendly and resource-saving society. Shale gas oil-based drilling cutting pyrolysis residues (ODPRs) have been used as the main research object to developing new technology which can convert the residues into a harmless and recyclable material. Using the test data of ODPR, we analyze the development prospect in the building material industry and provide a scheme to utilize this particular solid-waste efficiently...
June 12, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28602325/pigment-dispersion-syndrome-and%C3%A2-pigmentary-glaucoma-after-secondary-sulcus-transscleral-fixation-of-single-piece-foldable%C3%A2-posterior-chamber-intraocular-lenses%C3%A2-in%C3%A2-chinese-aphakic-patients
#2
Nianting Tong, Fuling Liu, Ting Zhang, Liangyu Wang, Zhanyu Zhou, Huimin Gong, Fuxiang Yuan
PURPOSE: To describe secondary pigment dispersion syndrome (PDS) and pigmentary glaucoma after secondary sulcus transscleral fixation of 1-piece hydrophobic acrylic foldable posterior chamber intraocular lenses (PC IOLs) in aphakic patients in a Chinese population. SETTING: Department of Ophthalmology, Qingdao Municipal Hospital, Qingdao, China. DESIGN: Retrospective case series. METHODS: This chart review included eyes that had secondary sulcus transscleral fixation of a 1-piece hydrophobic acrylic foldable PC IOL (Tecnis ZCB00) between March 2011 and March 2014...
May 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28589742/potential-prognostic-value-of-clinical-characteristics-hormone-status-and-major-depressive-disorder-in-breast-cancer
#3
Lingyun Hui, Tianhe Huang, Jie Lian, Fuling Zhou, Chengge Gao, Yan Lin, Honglei Tu, Kejun Nan, Zongfang Li, Yongchang Wei
AIM: To identify independent factors predicting overall survival (OS) of breast cancer (BC) patients. PATIENTS & METHODS: Two hundred and eighty one women with BC were recruited and clinical characteristics including lymphovascular invasion, clinical stage of tumor node metastasis and positive axillary lymph nodes were documented; immunohistochemistry/fluorescence in situ hybridization was used to examine the expression of estrogen receptor, progesterone receptor, HER2 and Ki-67; major depressive disorder was assessed with Diagnostic and Statistical Manual of Mental Disorders V...
June 7, 2017: Future Oncology
https://www.readbyqxmd.com/read/28575936/solid-crystal-suspension-of-efavirenz-using-hot-melt-extrusion-exploring-the-role-of-crystalline-polyols-in-improving-solubility-and-dissolution-rate
#4
Jaywant N Pawar, Ritesh A Fule, Mohammed Maniruzzaman, Purnima D Amin
Poor aqueous solubility of drugs has emerged as a major issue for pharmaceutical scientists from many decades. The current study explores the manufacture and development of a thermodynamically stabilized solid crystal suspension (SCS) of poorly water soluble drug efavirenz via hot melt extrusion. Efavirenz is a non-nucleoside reverse transcriptase inhibitor and belongs to BCS class II. The SCS was prepared using pearlitol and xylitol as a crystalline carrier. The drug-excipient blend was processed by hot melt extrusion with up to 50% (w/w) drug loading...
September 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28525899/the-prognostic-value-of-long-noncoding-rnas-in-prostate-cancer-a-systematic-review-and-meta-analysis
#5
Weijie Ma, Xi Chen, Lu Ding, Jianhong Ma, Wei Jing, Tian Lan, Haseeb Sattar, Yongchang Wei, Fuling Zhou, Yufeng Yuan
The abnormally expressed LncRNAs played irreplaceable roles in the prognosis of prostate cancer (PCa). Therefore, we conducted this systematic review and meta-analysis to summarize the association between the expression of LncRNAs, prognosis and clinicopathology of PCa. 18 eligible studies were recruited into our analysis, including 18 on prognosis and 9 on clinicopathological features. Results indicated that aberrant expression of LncRNAs was significantly associated with biochemical recurrence-free survival (BCR-FS) (HR = 1...
May 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28508448/a-novel-multi-epitope-vaccine-from-mmsa-1-and-dkk1-for-multiple-myeloma-immunotherapy
#6
Chenyang Lu, Shan Meng, Yanxia Jin, Wanggang Zhang, Zongfang Li, Fang Wang, Feng Wang-Johanning, Yongchang Wei, Hailing Liu, Honglei Tu, Dan Su, Aili He, Xingmei Cao, Fuling Zhou
The identification of novel tumour-associated antigens is urgently needed to improve the efficacy of immunotherapy for multiple myeloma (MM). In this study, we identified a membrane protein MMSA-1 (multiple myeloma special antigen-1) that was specifically expressed in MM and exhibited significantly positive correlation with MM. We then identified HLA-A*0201-restricted MMSA-1 epitopes and tested their cytotoxic T lymphocyte (CTL) response. The MMSA-1 epitope SLSLLTIYV vaccine was shown to induce an obvious CTL response in vitro...
May 16, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28483515/thioredoxin-1-promotes-colorectal-cancer-invasion-and-metastasis-through-crosstalk-with-s100p
#7
Feiyan Lin, Peili Zhang, Zhigui Zuo, Fule Wang, Ruichun Bi, Wenjing Shang, Aihua Wu, Ju Ye, Shaotang Li, Xuecheng Sun, Jianbo Wu, Lei Jiang
Thioredoxin-1 (Trx-1) is a small redox-regulating protein, which plays an important role in several cellular functions. Despite recent advances in understanding the biology of Trx-1, the role of Trx-1 and its underlying signaling mechanism in colorectal cancer (CRC) metastasis have not been extensively studied. In this study, we observed that Trx-1 expression is increased in CRC tissues compared to the paired non-cancerous tissues and is significantly correlated with clinical staging, lymph node metastasis and poor survival...
May 5, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28454398/immunological-effects-of-vaccines-combined-with-granulocyte-colony-stimulating-factor-on-a-murine-wehi-3-leukemia-model
#8
Jinqiu Chen, Miling Zhang, Fuling Zhou, Jin Wang, Ben Niu, Wanggang Zhang
Granulocyte colony-stimulating factor (G-CSF) mobilizes regulatory T cells (Tregs) from bone marrow into the peripheral blood, by reducing the expression of stromal cell-derived factor-1α (SDF-1α). However, G-CSF has rarely been studied in acute myeloid leukemia (AML) immunotherapy. The present study performed a Transwell migration assay in vitro to determine the contribution of SDF-1α to the migration of leukemia cells, and the effects of G-CSF were evaluated. The effects of G-CSF on SDF-1α and Tregs in the AML microenvironment were examined, by employing a WEHI-3-grafted BALB/c mouse AML model (AML-M4)...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454384/new-applications-of-the-acridine-orange-fluorescence-staining-method-screening-for-circulating-tumor-cells
#9
Min Liu, Ruizhe Li, Yang Tang, Jiwu Chang, Rong Han, Shumin Zhang, Ning Jiang, Fuling Ma
The aim of the present study was to explore use of the acridine orange fluorescence (AO-F) staining method for screening of circulating tumor cells (CTCs) in renal cell carcinoma (RCC) patients. The AO-F positive staining rate of live and dead tumor cells was calculated. The positive staining rate in the live group was 93.4±3.0%, while the dead group failed to emit specific fluorescence. A known number of tumor cells were added to peripheral blood, and the detection sensitivity of the four groups (50, 100, 200 and 500 cells/tube) was 10...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28448931/tree-growth-climate-relationships-in-a-forest-plot-network-on-mediterranean-mountains
#10
Nikolaos M Fyllas, Anastasia Christopoulou, Alexandros Galanidis, Chrysanthi Z Michelaki, Panayiotis G Dimitrakopoulos, Peter Z Fulé, Margarita Arianoutsou
In this study we analysed a novel tree-growth dataset, inferred from annual ring-width measurements, of 7 forest tree species from 12 mountain regions in Greece, in order to identify tree growth - climate relationships. The tree species of interest were: Abies cephalonica, Abies borisii-regis, Picea abies, Pinus nigra, Pinus sylvestris, Fagus sylvatica and Quercus frainetto growing across a gradient of climate conditions with mean annual temperature ranging from 5.7 to 12.6°C and total annual precipitation from 500 to 950mm...
November 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28410530/metformin-attenuated-endotoxin-induced-acute-myocarditis-via-activating-ampk
#11
Gang Liu, Kejia Wu, Li Zhang, Jie Dai, Wei Huang, Ling Lin, Pu Ge, Fuling Luo, Han Lei
Metformin is a widely used anti-diabetic drug and increasing evidence suggests that metformin have profound cardioprotective effects under both diabetic and non-diabetic situations. The protective benefits of metformin have been proved in diabetic patients with cardiovascular complications and in experimental animals with myocardial infarction and cardiac hypertrophy. In the present study, we found that treatment with metformin inhibited the cardiac expression of pro-inflammatory cytokines including tumor necrosis factor alpha (TNF-α), interleukin 1 beta (IL-1β) and interleukin 6 (IL-6) in endotoxin-challenged mice...
April 11, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28369451/association-between-birthweight-and-later-body-mass-index-an-individual-based-pooled-analysis-of-27-twin-cohorts-participating-in-the-codatwins-project
#12
Aline Jelenkovic, Yoshie Yokoyama, Reijo Sund, Kirsi H Pietiläinen, Yoon-Mi Hur, Gonneke Willemsen, Meike Bartels, Toos Cem van Beijsterveldt, Syuichi Ooki, Kimberly J Saudino, Maria A Stazi, Corrado Fagnani, Cristina D'Ippolito, Tracy L Nelson, Keith E Whitfield, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Kauko Heikkilä, Tessa L Cutler, John L Hopper, Jane Wardle, Clare H Llewellyn, Abigail Fisher, Robin P Corley, Brooke M Huibregtse, Catherine A Derom, Robert F Vlietinck, Ruth Jf Loos, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Adam D Tarnoki, David L Tarnoki, S Alexandra Burt, Kelly L Klump, Juan R Ordoñana, Juan F Sánchez-Romera, Lucia Colodro-Conde, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Jennifer R Harris, Ingunn Brandt, Thomas Sevenius Nilsen, Jeffrey M Craig, Richard Saffery, Finn Rasmussen, Per Tynelius, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Claire Ma Haworth, Robert Plomin, Fuling Ji, Feng Ning, Zengchang Pang, Esther Rebato, Robert F Krueger, Matt McGue, Shandell Pahlen, Dorret I Boomsma, Thorkild Ia Sørensen, Jaakko Kaprio, Karri Silventoinen
Background: There is evidence that birthweight is positively associated with body mass index (BMI) in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment. We analysed the association between birthweight and BMI from infancy to adulthood within twin pairs, which provides insights into the role of genetic and environmental individual-specific factors. Methods: This study is based on the data from 27 twin cohorts in 17 countries...
March 19, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28337842/halogenated-briarane-diterpenes-with-acetyl-migration-from-the-gorgonian-coral-junceella-fragilis
#13
Wei Cheng, Xiaodan Li, Fuling Yin, Leen van Ofwegen, Wenhan Lin
Chemical examination of the gorgonian coral Junceella fragilis resulted in the isolation of four pairs of acetyl isomers belonging to briarane diterpenoids, including five new compounds. Their structures were determined on the basis of extensive spectroscopic (IR, MS, NMR and single-crystal X-ray diffraction) analysis in association with the chemical conversion. Each pair of isomers featured by dynamical interconversion through as acetyl migration in 1,2-diol, which was postulated to be generated under the formation of a cyclic orthoacetate intermediate...
March 24, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28316984/leptin-leprb-expressed-in-gastric-cancer-patients-and-related-to-cancer-related-depression
#14
Yunbao Pan, Fuling Zhou, Chenyan He, Lingyun Hui, Tianhe Huang, Yongchang Wei
Depression is the most common psychiatric disorder among cancer patients. Studies have not only highlighted that leptin and its receptor (LepRb) are independent poor prognostic factors in gastric cancer (GC) patients but also shown that the leptin-LepRb is necessary for antidepressant-like behaviors. In this study, we examined the serum and tissue leptin-LepRb expression in GC patients. Enzyme-linked immunosorbent assay showed that depressive GC patients had significantly higher serum leptin-LepRb than healthy donors...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28270496/jab1-csn5-thioredoxin-signaling-in-relapsed-acute-monocytic-leukemia-under-oxidative-stress
#15
Fuling Zhou, Yunbao Pan, Yongchang Wei, Ronghua Zhang, Gaigai Bai, Qiuju Shen, Shan Meng, Xiao-Feng Le, Michael Andreeff, Francois X Claret
PURPOSE: High levels of ROS and ineffective antioxidant systems contribute to oxidative stress, which affects the function of hematopoietic cells in acute myeloid leukemia (AML); however, the mechanisms by which ROS lead to malignant transformation in relapsed AML-M5 are not completely understood. We hypothesized that alterations in intracellular ROS would trigger AML-M5 relapse by activating the intrinsic pathway. EXPERIMENTAL DESIGN: We studied ROS levels and conducted JAB1/COPS5 and TRX gene expression analyses with blood samples obtained from 60 matched AML-M5 patients at diagnosis and relapse and conducted mechanism studies of Jab1's regulation of Trx in leukemia cell lines...
March 7, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28248091/high-density-single-layer-coating-of-gold-nanoparticles-onto-multiple-substrates-by-using-an-intrinsically-disordered-protein-of-%C3%AE-synuclein-for-nanoapplications
#16
Ghibom Bhak, Junghee Lee, Chang-Hyun Kim, Dong Young Chung, Jin Hyoun Kang, Soojung Oh, Jungsup Lee, Jin Soo Kang, Ji Mun Yoo, Jee Eun Yang, Kun Yil Rhoo, Sunghak Park, Somin Lee, Ki Tae Nam, Noo Li Jeon, Jyongsik Jang, Byung Hee Hong, Yung-Eun Sung, Myung-Han Yoon, Seung R Paik
Functional graffiti of nanoparticles onto target surface is an important issue in the development of nanodevices. A general strategy has been introduced here to decorate chemically diverse substrates with gold nanoparticles (AuNPs) in the form of a close-packed single layer by using an omni-adhesive protein of α-synuclein (αS) as conjugated with the particles. Since the adsorption was highly sensitive to pH, the amino acid sequence of αS exposed from the conjugates and its conformationally disordered state capable of exhibiting structural plasticity are considered to be responsible for the single-layer coating over diverse surfaces...
March 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28244703/association-between-fruit-vegetable-seafood-and-dairy-intake-and-a-reduction-in-the-prevalence-of-type-2-diabetes-in-qingdao-china
#17
Jiwei Liang, Yanlei Zhang, Aili Xue, Jianping Sun, Xin Song, Bai Xue, Fuling Ji, Weiguo Gao, Liang He, Zengchang Pang, Qing Qiao, Feng Ning
BACKGROUND AND OBJECTIVES: Fruit, vegetable, seafood, and dairy intake may reduce the risk of type 2 diabetes, but this relationship is unclear. We aimed to examine the associations between fruit, vegetable, seafood, and dairy intake and type 2 diabetes prevalence in a Chinese population. METHODS AND STUDY DESIGN: A total of 4,343 individuals aged 35-74 years participated in a population-based cross-sectional study in Qingdao, China. The frequency and quantity of fruit, vegetable, seafood, and dairy intake were determined using a standard food frequency questionnaire...
March 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28214839/t-cell-associated-immunotherapy-for-hepatocellular-carcinoma
#18
REVIEW
Weijie Ma, Long Wu, Fuling Zhou, Zhenfei Hong, Yufeng Yuan, Zhisu Liu
Hepatocellular carcinoma (HCC) is one of the most common malignant diseases worldwide with limited therapeutic options. Accumulating evidences suggest that immunotherapy could be a promising option for treating HCC. T cell-associated immunotherapy lights up the hope for the improvement of complementary approach to conventional HCC treatments, which needs further research to consummate the clinical consequences. The present work reviewed several T cells associated cellular immunotherapies for HCC, including immune checkpoint blockade, gene-engineered T cells, bispecific T cell engagers, and so on...
2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28164471/porous-zirconium-furandicarboxylate-microspheres-for-efficient-redox-conversion-of-biofuranics
#19
Hu Li, Xiaofang Liu, Tingting Yang, Wenfeng Zhao, Shunmugavel Saravanamurugan, Song Yang
Biofuranic compounds, typically derived from C5 and C6 carbohydrates, have been extensively studied as promising alternatives to chemicals based on fossil resources. The present work reports the simple assembly of biobased 2,5-furandicarboxylic acid (FDCA) with different metal ions to prepare a range of metal-FDCA hybrids under hydrothermal conditions. The hybrid materials were demonstrated to have porous structure and acid-base bifunctionality. Zr-FDCA-T, in particular, showed a microspheric structure, high thermostability (ca...
April 22, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28120217/current-treatment-options-of-t-cell-associated-immunotherapy-in-multiple-myeloma
#20
REVIEW
Hailing Liu, Yunbao Pan, Shan Meng, Wanggang Zhang, Fuling Zhou
Multiple myeloma (MM) is a complex disease and is presently an incurable malignant plasma cell tumor. Although the introduction of proteasome inhibitor and the immunomodulators markedly improved the effect of myeloma therapy, most patients still suffer from relapse even with an initially effective therapy. Accumulating evidence suggests that immunotherapy is a promising option in treating MM. And T cell plays crucial role through inducing sustained immune response in vivo in the immunotherapy of tumors. In this article, we will discuss progress of several T cell-based immunotherapies with insight into how they eradicate myeloma cells and their disadvantages...
January 24, 2017: Clinical and Experimental Medicine
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