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Nutrition/nutrients

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https://www.readbyqxmd.com/read/28723566/genome-wide-rnai-screen-for-fat-regulatory-genes-in-c-%C3%A2-elegans-identifies-a-proteostasis-ampk-axis-critical-for-starvation-survival
#1
Christopher M Webster, Elizabeth C Pino, Christopher E Carr, Lianfeng Wu, Ben Zhou, Lucydalila Cedillo, Michael C Kacergis, Sean P Curran, Alexander A Soukas
Organisms must execute metabolic defenses to survive nutrient deprivation. We performed a genome-wide RNAi screen in Caenorhabditis elegans to identify fat regulatory genes indispensable for starvation resistance. Here, we show that opposing proteostasis pathways are principal determinants of starvation survival. Reduced function of cytoplasmic aminoacyl tRNA synthetases (ARS genes) increases fat mass and extends starvation survival, whereas reduced proteasomal function reduces fat and starvation survival. These opposing pathways converge on AMP-activated protein kinase (AMPK) as the critical effector of starvation defenses...
July 18, 2017: Cell Reports
https://www.readbyqxmd.com/read/28722768/international-summit-on-the-nutrition-of-adolescent-girls-and-young-women-consensus-statement
#2
Nancy Krebs, Susan Bagby, Zulfiqar A Bhutta, Kathryn Dewey, Caroline Fall, Fred Gregory, William Hay, Lisa Rhuman, Christine Wallace Caldwell, Kent L Thornburg
An international summit focusing on the difficult challenge of providing adequate nutrition for adolescent girls and young women in low- and middle-income countries was held in Portland, Oregon in 2015. Sixty-seven delegates from 17 countries agreed on a series of recommendations that would make progress toward improving the nutritional status of girls and young women in countries where their access to nutrition is compromised. Delegate recommendations include: (1) elevate the urgency of nutrition for girls and young women to a high international priority, (2) raise the social status of girls and young women in all regions of the world, (3) identify major knowledge gaps in the biology of adolescence that could be filled by robust research efforts, (4) and improve access to nutrient-rich foods for girls and young women...
July 19, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28722751/graded-replacement-of-maize-grain-with-molassed-sugar-beet-pulp-modulated-ruminal-microbial-community-and-fermentation-profile-in-vitro
#3
Matthias Münnich, Annabella Khol-Parisini, Fenja Klevenhusen, Barbara Metzler-Zebeli, Qendrim Zebeli
BACKGROUND: Molassed sugar beet pulp (Bp) is a viable alternative to grains in cattle nutrition for reducing human edible energy input. Yet, little is known about the effects of high inclusion rates of Bp on rumen microbiota. This study used an in vitro approach and the qPCR technique to establish the effects of a graded replacement of maize grain (MG) by Bp on the ruminal microbial community, fermentation profile, and nutrient degradation. RESULTS: Six different amounts of Bp (0 to 400 g kg(-1) ) which replaced MG in the diet were tested, using the in vitro semi continuous rumen simulation technique...
July 19, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28720150/metabotyping-and-its-application-in-targeted-nutrition-an-overview
#4
Anna Riedl, Christian Gieger, Hans Hauner, Hannelore Daniel, Jakob Linseisen
Metabolic diversity leads to differences in nutrient requirements and responses to diet and medication between individuals. Using the concept of metabotyping - that is, grouping metabolically similar individuals - tailored and more efficient recommendations may be achieved. The aim of this study was to review the current literature on metabotyping and to explore its potential for better targeted dietary intervention in subjects with and without metabolic diseases. A comprehensive literature search was performed in PubMed, Google and Google Scholar to find relevant articles on metabotyping in humans including healthy individuals, population-based samples and patients with chronic metabolic diseases...
July 19, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28718996/production-of-ligninolytic-enzymes-and-some-diffusible-antifungal-compounds-by-white-rot-fungi-using-potato-solid-wastes-as-the-sole-nutrient-source
#5
H Schalchli, E Hormazábal, O Rubilar, G Briceño, A Mutis, G J Zocolo, C Diez
AIMS: The aim of this study was to evaluate the synthesis of ligninolytic enzymes and some diffusible antifungal compounds by white-rot fungi using peels or discarded potato as the sole nutrient source. METHODS AND RESULTS: The strain Trametes hirsuta Ru-513 has been highlighted for its laccase activity (595 ± 33 U l(-1) ), which is able to decolourise 87% of an anthraquinone dye using potato peels as the sole nutritional support. A native polyacrylamide gel of laccase proteins showed the presence of two isoenzymes, corresponding to proteins of 56 and 67 kDa, which were detected by SDS-PAGE...
July 18, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28718824/associations-between-red-meat-intakes-and-the-micronutrient-intake-and-status-of-uk-females-a-secondary-analysis-of-the-uk-national-diet-and-nutrition-survey
#6
Emma Derbyshire
Blanket health messages to lower red meat intakes are being communicated at present. These could have adverse implications on the micronutrient quality of women's diets. The current paper evaluates the nutritional impact of lower red meat intakes on British women's micronutrient intakes and status. A secondary analysis of the UK National Diet and Nutrition Survey was undertaken using data from years 2008/2009 to 2011/2012. This was comprised of dietary and blood analyte data from 1384 and 641 females aged 11 to 64 years...
July 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28718015/capable-and-credible-challenging-nutrition-science
#7
EDITORIAL
Bart Penders, Anna Wolters, Edith F Feskens, Fred Brouns, Machteld Huber, Els L M Maeckelberghe, Gerjan Navis, Theo Ockhuizen, Jogchum Plat, Jan Sikkema, Marianne Stasse-Wolthuis, Pieter van 't Veer, Marcel Verweij, Jan de Vries
Nutrition science has enriched our understanding of how to stay healthy by producing valuable knowledge about the interaction of nutrients, food, and the human body. Nutrition science also has raised societal awareness about the links between food consumption and well-being, and provided the basis for food regulations and dietary guidelines. Its collaborative and interdisciplinary research has accomplished much, scientifically and socially. Despite this, nutrition science appears to be in crisis and is currently confronted with a public reluctance to trust nutritional insights...
July 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28715992/the-hibernator-microbiome-host-bacterial-interactions-in-an-extreme-nutritional-symbiosis
#8
Hannah V Carey, Fariba M Assadi-Porter
Animals that undergo seasonal cycles of feeding and fasting have adaptations that maintain integrity of organ systems when dietary nutrients are lacking. Food deprivation also challenges the gut microbiota, which relies heavily on host diet for metabolic substrates and the gastrointestinal tract, which is influenced by enteral nutrients and microbial activity. Winter fasting in hibernators shifts the microbiota to favor taxa with the capacity to degrade and utilize host-derived substrates and disfavor taxa that prefer complex plant polysaccharides...
July 17, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28715990/single-subject-studies-in-translational-nutrition-research
#9
Nicholas J Schork, Laura H Goetz
There is a great deal of interest in personalized, individualized, or precision interventions for disease and health-risk mitigation. This is as true of nutrition-based intervention and prevention strategies as it is for pharmacotherapies and pharmaceutical-oriented prevention strategies. Essentially, technological breakthroughs have enabled researchers to probe an individual's unique genetic, biochemical, physiological, behavioral, and exposure profile, allowing them to identify very specific and often nuanced factors that an individual might possess, which may make it more or less likely that he or she responds favorably to a particular intervention (e...
July 17, 2017: Annual Review of Nutrition
https://www.readbyqxmd.com/read/28715784/elemental-content-of-the-placenta-a-comparison-between-two-high-risk-obstetrical-populations-adult-women-carrying-multiples-and-adolescents-carrying-singletons
#10
Paolo de Angelis, Richard K Miller, Thomas H Darrah, Philip J Katzman, Eva K Pressman, Tera R Kent, Kimberly O O'Brien
BACKGROUND: The placenta is responsible for the exchange of nutrients and for preventing harmful compounds from entering the fetal circulation. With increasing industrialization, exposures to commercial and toxic metals become a concern for both pregnant women and those planning a pregnancy. The understanding of transport mechanisms and pharmacokinetics for most inorganic elements is incomplete and limited to normal term deliveries. OBJECTIVES: To obtain novel data on 46 inorganic elements in placentae from two high-risk obstetric populations, women carrying multiples and adolescents carrying singletons, evaluating differences, if present, and identifying predictors of placental content...
July 14, 2017: Environmental Research
https://www.readbyqxmd.com/read/28715656/the-prevalence-of-malnutrition-and-its-associated-risk-factors-among-women-of-reproductive-age-in-ziway-dugda-district-arsi-zone-oromia-regional-state-ethiopia
#11
Abebe Ferede, Firaol Lemessa, Mesfin Tafa, Solomon Sisay
OBJECTIVES: Adequate nutrition is an important factor to determine the health and well-being of women, children and society as a whole. Although various nutritional policies were formulated and aimed at reducing malnutrition at the global level, the magnitude of malnutrition (body mass index [BMI] <18.5 kg/m(2)) among women remained between 10% and 40% in most low- and middle-income countries. We aimed to determine the prevalence of malnutrition and to identify the associated risk factors among women of reproductive age...
July 14, 2017: Public Health
https://www.readbyqxmd.com/read/28714931/correlation-between-oxidative-stress-nutrition-and-cancer-initiation
#12
REVIEW
Subbroto Kumar Saha, Soo Bin Lee, Jihye Won, Hye Yeon Choi, Kyeongseok Kim, Gwang-Mo Yang, Ahmed Abdal Dayem, Ssang-Goo Cho
Inadequate or excessive nutrient consumption leads to oxidative stress, which may disrupt oxidative homeostasis, activate a cascade of molecular pathways, and alter the metabolic status of various tissues. Several foods and consumption patterns have been associated with various cancers and approximately 30-35% of the cancer cases are correlated with overnutrition or malnutrition. However, several contradictory studies are available regarding the association between diet and cancer risk, which remains to be elucidated...
July 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28714900/a-nutrigenomic-approach-to-non-alcoholic-fatty-liver-disease
#13
REVIEW
Paola Dongiovanni, Luca Valenti
Following the epidemics of obesity due to the consumption of high-calorie diet and sedentary lifestyle, nonalcoholic fatty liver disease (NAFLD) is now the leading cause of liver disease in Western countries. NAFLD is epidemiologically associated with metabolic syndrome and insulin resistance, and in susceptible individuals it may progress to cirrhosis and hepatocellular carcinoma. Genetic factors play a key role in NAFLD predisposition by interacting with nutritional and other environmental factors. To date, there is no drug therapy for the treatment of NAFLD, and the main clinical recommendation is lifestyle modification...
July 16, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28714768/macronutrient-composition-of-a-morning-meal-and-the-maintenance-of-attention-throughout-the-morning
#14
Tommy J Wilson, Michael J Gray, Jan-Willem Van Klinken, Melissa Kaczmarczyk, John J Foxe
BACKGROUND: At present, the impact of macronutrient composition and nutrient intake on sustained attention in adults is unclear, although some prior work suggests that nutritive interventions that engender slow, steady glucose availability support sustained attention after consumption. A separate line of evidence suggests that nutrient consumption may alter electroencephalographic markers of neurophysiological activity, including neural oscillations in the alpha-band (8-14 Hz), which are known to be richly interconnected with the allocation of attention...
July 17, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28714425/the-share-of-ultra-processed-foods-determines-the-overall-nutritional-quality-of-diets-in-brazil
#15
Maria Laura da Costa Louzada, Camila Zancheta Ricardo, Euridice Martinez Steele, Renata Bertazzi Levy, Geoffrey Cannon, Carlos Augusto Monteiro
OBJECTIVE: To estimate the dietary share of ultra-processed foods and to determine its association with the overall nutritional quality of diets in Brazil. DESIGN: Cross-sectional. SETTING: Brazil. SUBJECTS: A representative sample of 32 898 Brazilians aged ≥10 years was studied. Food intake data were collected. We calculated the average dietary content of individual nutrients and compared them across quintiles of energy share of ultra-processed foods...
July 17, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28714091/habitual-diet-and-diet-quality-in-irritable-bowel-syndrome-a%C3%A2-case-control-study
#16
E F Tigchelaar, Z Mujagic, A Zhernakova, M A M Hesselink, S Meijboom, C W M Perenboom, A A M Masclee, C Wijmenga, E J M Feskens, D M A E Jonkers
BACKGROUND: Diet is considered to be a key factor in symptom generation in Irritable Bowel Syndrome (IBS) and patients tend to exclude food products from their diet in pursue of symptom relief, which may impair diet quality. METHODS: We evaluated habitual dietary intake in IBS patients with regard to nutrients and food products using an extensive food frequency questionnaire. One hundred ninety-four IBS patients were compared to 186 healthy controls using multiple logistic regression analysis...
July 17, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28713382/recent-advances-on-nutrition-in-treatment-of-acute-pancreatitis
#17
REVIEW
Li-Long Pan, Jiahong Li, Muhammad Shamoon, Madhav Bhatia, Jia Sun
Acute pancreatitis (AP) is a common abdominal acute inflammatory disorder and the leading cause of hospital admission for gastrointestinal disorders in many countries. Clinical manifestations of AP vary from self-limiting local inflammation to devastating systemic pathological conditions causing significant morbidity and mortality. To date, despite extensive efforts in translating promising experimental therapeutic targets in clinical trials, disease-specific effective remedy remains obscure, and supportive care has still been the primary treatment for this disease...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28712380/influence-of-para-aminohippuric-acid-analysis-on-net-portal-drained-viscera-flux-of-nutrients-in-pigs
#18
I Fernández-Fígares, M Lachica, M L Rojas-Cano, A González-Casado
In nutrition studies, para-aminohippuric acid (PAH) is a marker frequently used to measure blood flow in pigs, which is essential for estimating portal-drained viscera (PDV) flux of nutrients. The aim of this study was to evaluate the PAH analytical method by means of qualimetric statistical procedures to estimate the matrix effect and the accuracy and limits of quantitation of the method. Net PDV flux of nutrients was determined in five multi-catheterized pigs using water, plasma or commercial serum as standard matrix...
July 17, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28712045/dynamics-of-soil-bacterial-communities-over-a-vegetation-season-relate-to-both-soil-nutrient-status-and-plant-growth-phenology
#19
Davide Francioli, Elke Schulz, François Buscot, Thomas Reitz
Soil microorganisms regulate element cycling and plant nutrition, mediate co-existence of neighbors, and stabilize plant communities. Many of these effects are dependent upon environmental conditions and, in particular, on nutrient quality and availability in soils. In this context, we set up a pot experiment in order to examine the combined effects of soil nutrient availability and microbial communities on plant-soil interactions and to investigate assemblage rules for soil bacterial communities under changed nutrient conditions...
July 15, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28710484/colored-and-fluorescent-nanofibrous-silk-as-a-physically-transient-chemosensor-and-vitamin-deliverer
#20
Kyungtaek Min, Sookyoung Kim, Chang Gun Kim, Sunghwan Kim
Biodegradable and physically transient optics represent an emerging paradigm in healthcare devices by harnessing optically active system and obviating issues with chronic uses. Light emitting components that can efficiently interact with their environments have advantages of high sensitivity, visibility, and wireless operation. Here, we report a novel combination of silk biopolymer and optically active organic dyes resulting in versatile fluorescent silk nanofibers (FSNs). FSNs generated by the electrospinning method exhibit attractive functions of the doped organic dyes along with programming the system that physically disappear at prescribed time...
July 14, 2017: Scientific Reports
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