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Nasal cannula

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https://www.readbyqxmd.com/read/29237436/high-flow-nasal-cannula-oxygen-therapy-versus-conventional-oxygen-therapy-in-patients-with-acute-respiratory-failure-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#1
Youfeng Zhu, Haiyan Yin, Rui Zhang, Jianrui Wei
BACKGROUND: Acute respiratory failure (ARF) is a common and life-threatening medical emergency in patients admitted to the hospital. Currently, there is a lack of large-scale evidence on the use of high-flow nasal cannulas (HFNC) in patients with ARF. In this systematic review and meta-analysis, we evaluated whether there were differences between HFNC therapy and conventional oxygen therapy (COT) for treating patients with ARF. METHODS: The EMBASE, Medline, and Wanfang databases and the Cochrane Library were searched...
December 13, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29236544/gene-therapy-for-cystic-fibrosis-improved-delivery-techniques-and-conditioning-with-lysophosphatidylcholine-enhance-lentiviral-gene-transfer-in-mouse-lung-airways
#2
Patricia Cmielewski, Nigel Farrow, Sharnna Devereux, David Parsons, Martin Donnelley
Purpose/Aim: Cystic fibrosis (CF) is the most common, fatal recessive genetic disease among the Caucasian population. Gene therapy has the potential to treat CF long term, however physiological barriers can prevent VSV-G pseudotyped lentiviral (LV) vectors from efficiently accessing the relevant receptors on the basolateral membrane of airway epithelial cells. The aims of this experiment were to use our new dose delivery techniques to determine whether conditioning the mouse lung conducting airways with lysophosphatidylcholine (LPC) improves the level of airway gene expression...
December 13, 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/29221274/predictors-of-high-flow-nasal-cannula-failure-in-immunocompromised-patients-with-acute-respiratory-failure-due-to-non-hiv-pneumocystis-pneumonia
#3
Won-Young Kim, Heungsup Sung, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Background: To evaluate the predictors of high flow nasal cannula (HFNC) failure in pneumocystis pneumonia (PCP) patients with acute respiratory failure (ARF). Methods: Fifty-two non-HIV-related PCP subjects were divided into a HFNC success group (44%) and a HFNC failure group (who required mechanical ventilation (MV) despite HFNC application) (56%). The clinical characteristics and physiologic effects were retrospectively reviewed and compared between the groups...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29208754/proactive-use-of-high-flow-nasal-cannula-with-critically-ill-subjects
#4
Keith D Lamb, Sarah K Spilman, Trevor W Oetting, Julie A Jackson, Matthew W Trump, Sheryl M Sahr
INTRODUCTION: It has been suggested that use of a high-flow nasal cannula (HFNC) could be a first-line therapy for patients with acute hypoxic respiratory failure. The purpose of this study was to determine if protocolized use of HFNC decreases unplanned intubation and adverse outcomes in an ICU population. METHODS: The study was a prospective evaluation of 2 cohorts who received HFNC per protocol. Control groups were retrospective selections of subjects who received HFNC in the pre-protocol period...
December 5, 2017: Respiratory Care
https://www.readbyqxmd.com/read/29208322/face-mask-leak-with-nasal-cannula-during-noninvasive-positive-pressure-ventilation-a-randomized-crossover-trial
#5
Derek J Brown, Stephen M Carroll, Michael D April
BACKGROUND: Nasal cannula can achieve apneic oxygenation during emergency intubation. However, pre-procedure nasal cannula placement may be difficult in patients undergoing non-invasive positive pressure ventilation (NPPV) prior to intubation. Our objective was to compare mask leak during NPPV with versus without simultaneous application of nasal cannula. We hypothesized mask leak would be no worse with concomitant use of nasal cannula (non-inferiority design). METHODS: We performed a randomized crossover non-inferiority study of healthy volunteers...
December 2, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29198536/infants-with-atypical-presentations-of-alveolar-capillary-dysplasia-with-misalignment-of-the-pulmonary-veins-who-underwent-bilateral-lung-transplantation
#6
Christopher T Towe, Frances V White, R Mark Grady, Stuart C Sweet, Pirooz Eghtesady, Daniel J Wegner, Partha Sen, Przemyslaw Szafranski, Pawel Stankiewicz, Aaron Hamvas, F Sessions Cole, Jennifer A Wambach
OBJECTIVE: To describe disease course, histopathology, and outcomes for infants with atypical presentations of alveolar capillary dysplasia with misalignment of the pulmonary veins (ACDMPV) who underwent bilateral lung transplantation. STUDY DESIGN: We reviewed clinical history, diagnostic studies, explant histology, genetic sequence results, and post-transplant course for 6 infants with atypical ACDMPV who underwent bilateral lung transplantation at St. Louis Children's Hospital...
November 30, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29187008/cost-effectiveness-analysis-of-the-use-of-high-flow-oxygen-through-nasal-cannula-in-intensive-care-units-in-nhs-england
#7
Emily Eaton Turner, Michelle Jenks
Objective To estimate the cost-effectiveness of Nasal High Flow (NHF) in the intensive care unit (ICU) compared with standard oxygen or non-invasive ventilation (NIV) from a UK NHS perspective. Methods Three cost-effectiveness models were developed to reflect scenarios of NHF use: first-line therapy (pre-intubation model); post-extubation in low-risk, and high-risk patients. All models used randomised control trial data on the incidence of intubation/re-intubation, events leading to intubation/re-intubation, mortality and complications...
November 30, 2017: Expert Review of Pharmacoeconomics & Outcomes Research
https://www.readbyqxmd.com/read/29186485/indications-and-practical-approach-to-non-invasive-ventilation-in-acute-heart-failure
#8
Josep Masip, W Frank Peacock, Susanna Price, Louise Cullen, F Javier Martin-Sanchez, Petar Seferovic, Alan S Maisel, Oscar Miro, Gerasimos Filippatos, Christiaan Vrints, Michael Christ, Martin Cowie, Elke Platz, John McMurray, Salvatore DiSomma, Uwe Zeymer, Hector Bueno, Chris P Gale, Maddalena Lettino, Mucio Tavares, Frank Ruschitzka, Alexandre Mebazaa, Veli-Pekka Harjola, Christian Mueller
In acute heart failure (AHF) syndromes significant respiratory failure (RF) is essentially seen in patients with acute cardiogenic pulmonary oedema (ACPE) or cardiogenic shock (CS). Non-invasive ventilation (NIV), the application of positive intrathoracic pressure through an interface, has shown to be useful in the treatment of moderate to severe RF in several scenarios. There are two main modalities of NIV: continuous positive airway pressure (CPAP) and pressure support ventilation (NIPSV) with positive end expiratory pressure...
November 26, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29174453/correlation-of-high-flow-nasal-cannula-outlet-area-with-gas-clearance-and-pressure-in-adult-upper-airway-replicas
#9
REVIEW
Charles P Moore, Ira M Katz, Georges Caillibotte, Warren H Finlay, Andrew R Martin
BACKGROUND: Primary benefits of high flow nasal cannula therapy include washout of carbon dioxide rich exhaled gas and increased airway pressures during tidal breathing. This work reports on the influence of high flow nasal cannula outlet area on upper airways gas clearance and tracheal pressures using measurements in five realistic adult nose-throat airway replicas. METHODS: Two commercial high flow nasal cannulas and one generic nasal cannula of varying size were compared...
November 11, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/29171661/a-randomised-controlled-trial-comparing-high-flow-nasal-oxygen-with-standard-management-for-conscious-sedation-during-bronchoscopy
#10
N Douglas, I Ng, F Nazeem, K Lee, P Mezzavia, R Krieser, D Steinfort, L Irving, R Segal
Traditional conscious sedation for endobronchial ultrasound procedures places patients at risk of desaturation, and high-flow nasal oxygen may reduce the risk. We designed a parallel-group randomised controlled trial of high-flow nasal oxygen at a flow rate of 30-70 l.min(-1) via nasal cannulae, compared with standard oxygen therapy at 10 l.min(-1) via a bite block in adults planned for conscious sedation for endobronchial ultrasound. The primary outcome was the proportion of patients experiencing desaturation (defined as SpO2 < 90%)...
November 24, 2017: Anaesthesia
https://www.readbyqxmd.com/read/29158751/high-flow-nasal-cannula-is-there-a-role-in-copd
#11
Nicholas S Hill
No abstract text is available yet for this article.
2017: Tanaffos
https://www.readbyqxmd.com/read/29149868/can-high-flow-nasal-cannula-reduce-the-rate-of-reintubation-in-adult-patients-after-extubation-a-meta-analysis
#12
Yue-Nan Ni, Jian Luo, He Yu, Dan Liu, Bin-Miao Liang, Rong Yao, Zong-An Liang
BACKGROUND: The effects of high flow nasal cannula (HFNC) on adult patients after extubation remain controversial. We aimed to further determine the effectiveness of HFNC in comparison to noninvasive positive pressure ventilation (NIPPV) and conventional oxygen therapy (COT). METHODS: The Pubmed, Embase, Medline, Cochrane Central Register of Controlled Trails (CENTRAL) as well as the Information Sciences Institute (ISI) Web of Science were searched for all the controlled study comparing HFNC with NIPPV and COT in adult patients after extubation...
November 17, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29149690/a-modified-montpellier-protocol-for-intubating-intensive-care-unit-patients-is-associated-with-an-increase-in-first-pass-intubation-success-and-fewer-complications
#13
Keith A Corl, Christopher Dado, Ankita Agarwal, Nader Azab, Tim Amass, Sarah J Marks, Mitchell M Levy, Roland C Merchant, Jason Aliotta
BACKGROUND: The Montpellier protocol for intubating patients in the intensive care unit (ICU) is associated with a decrease in intubation-related complications. We sought to determine if implementation of a simplified version of the Montpellier protocol that removed selected components and allowed for a variety of pre-oxygenation modalities increased first-pass intubation success and reduced intubation-related complications. METHODS: A prospective pre/post-comparison of a modified Montpellier protocol in two medical and one medical/surgical/cardiac ICU within a hospital system...
November 10, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/29148988/humidified-high-flow-nasal-cannula-oxygen-more-than-just-supplemental-oxygen
#14
Neil R MacIntyre
No abstract text is available yet for this article.
December 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29144160/high-flow-nasal-cannula-oxygen-in-adults-an-evidence-based-assessment
#15
Matthew G Drake
High flow nasal cannula oxygenation has distinct advantages over other oxygen devices due to its unique effects on respiratory physiology. In particular, adjustable oxygen delivery and flow-dependent carbon dioxide clearance from the upper airway reduce work of breathing and can better match inspiratory demand during respiratory distress. Historically, few studies had evaluated whether the physiologic effects of these devices translated into clinical benefit. However, recent publications have begun to address this knowledge gap...
November 16, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29099420/predictors-of-intubation-in-patients-with-acute-hypoxemic-respiratory-failure-treated-with-a-noninvasive-oxygenation-strategy
#16
Jean-Pierre Frat, Stéphanie Ragot, Rémi Coudroy, Jean-Michel Constantin, Christophe Girault, Gwénael Prat, Thierry Boulain, Alexandre Demoule, Jean-Damien Ricard, Keyvan Razazi, Jean-Baptiste Lascarrou, Jérôme Devaquet, Jean-Paul Mira, Laurent Argaud, Jean-Charles Chakarian, Muriel Fartoukh, Saad Nseir, Alain Mercat, Laurent Brochard, René Robert, Arnaud W Thille
OBJECTIVES: In patients with acute hypoxemic respiratory failure, noninvasive ventilation and high-flow nasal cannula oxygen are alternative strategies to conventional oxygen therapy. Endotracheal intubation is frequently needed in these patients with a risk of delay, and early predictors of failure may help clinicians to decide early. We aimed to identify factors associated with intubation in patients with acute hypoxemic respiratory failure treated with different noninvasive oxygenation techniques...
November 2, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29095428/how-does-high-flow-nasal-cannulae-compare-to-nasal-cpap-for-treatment-of-early-respiratory-distress
#17
S Parmekar, J Hagan
No abstract text is available yet for this article.
November 2, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29095183/the-effect-of-apneic-oxygenation-on-reducing-hypoxemia-during-rapid-sequence-induction-and-intubation-in-the-acutely-ill-or-injured
#18
Autumn Riddell
Apneic oxygenation during intubation is the application of oxygen via a nasal cannula, which is left in place throughout laryngoscopy. The flow rate of oxygen is set to at least 15 L/min and theoretically reduces the risk of oxygen desaturation and hypoxemia during the procedure. Over the last 5 years, there have been several studies published on this topic with differing results. Despite conflicting results, use of apneic oxygenation is becoming more prevalent and is being implemented into standard operating procedures in some clinical settings...
October 2017: Advanced Emergency Nursing Journal
https://www.readbyqxmd.com/read/29071075/evaluation-by-various-methods-of-the-physiological-mechanism-of-a-high-flow-nasal-cannula-hfnc-in-healthy-volunteers
#19
Miyuki Okuda, Nobuya Tanaka, Kazuyuki Naito, Takao Kumada, Koji Fukuda, Yuto Kato, Yuto Kido, Yutaro Okuda, Ryuji Nohara
INTRODUCTION: Several reports have described the usefulness of a high-flow nasal cannula (HFNC). However, the physiological mechanisms of this system are unclear. In the current study, various methods were used to investigate the physiological mechanisms of an HFNC in healthy volunteers. METHODS: The physiological mechanisms of the constant-flow and constant-pressure models of HFNC were studied in 10 healthy volunteers by the oesophageal balloon method, the electrical impedance method and the forced oscillation technique (FOT)...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/29069260/the-value-of-high-flow-nasal-cannula-oxygen-therapy-after-extubation-in-patients-with-acute-respiratory-failure
#20
Hong-Zhuan Song, Juan-Xian Gu, Hui-Qing Xiu, Wei Cui, Gen-Sheng Zhang
OBJECTIVE: To investigate the value of high-flow nasal cannula oxygen therapy after extubation in patients with acute respiratory failure. METHODS: A single-center, prospective, randomized, controlled pilot trial was conducted between January 2013 and December 2014. Sixty enrolled patients were randomized immediately after extubation into either a high-flow nasal cannula group (n=30) or an air entrainment mask group (n=30) at a fixed inspired oxygen fraction (40%)...
October 2017: Clinics
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