keyword
https://read.qxmd.com/read/38164361/what-happens-to-the-osteoporotic-bone-mesenchymal-stem-cells-evidence-from-rna-sequencing
#1
JOURNAL ARTICLE
Mingyang Li, Rong Cong, Huadong Wang, Chao Ma, Yongwei Lv, Yang Zheng, Yantao Zhao, Qin Fu, Li Li
Evidence presented that osteoporosis is closely related to the dysfunction of bone mesenchymal stem cells (BMSCs). But most studies are insufficient to reveal what actually happens to the osteoporotic BMSCs. In this study, BMSCs were harvested from ovariectomized and sham-operated rats. After checking the characteristics of rat models and stem cells, the BMSCs were carried out for RNA sequencing. Part of the findings were verified that seven mRNAs (Abi3bp, Aifm3, Ccl11, Cdkn1c, Chst10, Id2, Vcam1) were significantly up-regulated in osteoporotic BMSCs while seven mRNAs (Cep63, Fgfr3, Myc, Omd, Pou2f1, Smarcal1, Timm10b) were down-regulated...
2024: International Journal of Medical Sciences
https://read.qxmd.com/read/37130875/evaluation-of-frax-in-patients-with-periprosthetic-fractures-following-primary-total-hip-and-knee-arthroplasty
#2
JOURNAL ARTICLE
Lukas A Holzer, Lisa Borotschnig, Gerold Holzer
The fracture risk assessment tool (FRAX) is a tool which calculates an individual 10-year fracture risk based on epidemiological data in patients with a risk of osteporosis. The aim of this study was to evaluate the value of FRAX to estimate the risk of postoperative periprosthetic fractures (PPF) in patients following with total hip and knee arthroplasty. 167 patients (137 periprosthetic fractures in total hip arthroplasty and 30 periprosthetic fractures in total knee arthroplasty) were included in this study...
May 2, 2023: Scientific Reports
https://read.qxmd.com/read/37117113/bone-health-in-prostate-cancer-survivors-recent-lessons-and-opportunities-for-improvement
#3
REVIEW
John K Lin, Ravi B Parikh
Prostate cancer survivors face an elevated lifetime risk of fracture due to factors that include older age, bony metastases, and use of androgen deprivation therapy in the curative setting, which increases the risk of osteoporosis and fracture. Management of bone health is critical to prevent fracture and other bone-related complications; however, routine bone health screening is seldom performed and is inadequate. In this mini-review, we discuss optimal bone health management for prostate cancer survivors who have received curative-intent therapy...
April 26, 2023: European Urology Focus
https://read.qxmd.com/read/24870725/serum-25-hydroxy-vitamin-d-status-is-not-related-to-osteopenia-osteoporosis-risk-in-colorectal-cancer-survivors
#4
JOURNAL ARTICLE
Muhammed Bulent Akinci, Mehmet Ali Nahit Sendur, Sercan Aksoy, Ozan Yazici, Nuriye Yildirim Ozdemir, Tugba Kos, Sebnem Yaman, Kadri Altundag, Nurullah Zengin
BACKGROUND: The incidence of colorectal cancer increases with vitamin D deficiency as shown in recently published studies. In addition, prospective investigations have indicated that low vitamin D levels may be associated with increased mortality of colorectal cancer, especially in stage III and IV cases. However, the exact incidence of vitamin D deficiency and the relation between vitamin D deficiency and osteopenia/osteporosis is still not known. The aim of this study is to identify severity of vitamin D deficiency and absolute risk factors of osteopenia/osteoporosis in colorectal cancer survivors...
2014: Asian Pacific Journal of Cancer Prevention: APJCP
https://read.qxmd.com/read/22820515/hiv-and-its-effects-on-bone-a-primer-for-rheumatologists
#5
REVIEW
Lydia Gedmintas, Daniel H Solomon
PURPOSE OF REVIEW: As patients with HIV are living longer because of effective treatments, rates of comorbid chronic diseases such as bone complications are increasing. There is a growing body of literature showing increased rates of osteopenia and osteporosis in the HIV population. Less is known about the risk of fracture, as well as other bone complications, such as avascular necrosis (AVN). RECENT FINDINGS: Increased rates of osteopenia and osteoporosis are seen in the HIV population, likely secondary to an interaction of traditional osteoporotic and HIV-specific risk factors, and possibly the effect of antiretroviral therapy (ART)...
September 2012: Current Opinion in Rheumatology
https://read.qxmd.com/read/18246929/-prevalence-of-osteoporosis-and-osteopenia-among-women-over-fifty-years-of-age-from-the-city-of-durango-mexico-diagnosed-by-forearm-dexa
#6
JOURNAL ARTICLE
J Andrés González-Arellano, Reynaldo H Milla-Villeda, Gloria E Hernández-Vera, Vicente Cisneros-Pérez, Brissia Lazalde, Miguel R Reyes
OBJECTIVE: To estimate the prevalence of osteopenia and osteporosis using distal forearm dual-energy X-ray absorptiometry among a random sample of women of 50 years or older living in the city of Durango, Mexico. MATERIAL AND METHODS: 258 women participated in a cross-sectional study fielded at the Osteoporosis Clinic of Durango. Bone mineral density was determined by dual-energy X-ray absorptiometry. Scanning was performed on the distal third of the dominant forearm...
September 2007: Gaceta Médica de México
https://read.qxmd.com/read/16521798/-diagnosis-of-osteporosis
#7
JOURNAL ARTICLE
Takayuki Hosoi
No abstract text is available yet for this article.
January 2006: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://read.qxmd.com/read/12826169/alendronate-for-treatment-of-renal-transplant-patients-with-osteoporosis
#8
COMPARATIVE STUDY
J V Torregrosa, A Moreno, A Gutierrez, S Vidal, F Oppenheimer
UNLABELLED: Osteoporosis is a frequent complication after renal transplantation. Some workers have shown that bisphosphonates may be effective to prevent and treat corticosteroid-induced osteoporosis in these patients. In this study we report our experience with administration of the biphosphonate alendronate to treat renal transplanted patients with established osteoporosis. MATERIALS AND METHODS: Twelve to 24 months after transplantation (9 women, 5 men) 14 renal transplant patient were treated with alendronate and 12 patients (7 women, 5 men) were untreated...
June 2003: Transplantation Proceedings
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