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https://www.readbyqxmd.com/read/28503375/network-science-meets-respiratory-medicine-for-osas-phenotyping-and-severity-prediction
#1
Stefan Mihaicuta, Mihai Udrescu, Alexandru Topirceanu, Lucretia Udrescu
Obstructive sleep apnea syndrome (OSAS) is a common clinical condition. The way that OSAS risk factors associate and converge is not a random process. As such, defining OSAS phenotypes fosters personalized patient management and population screening. In this paper, we present a network-based observational, retrospective study on a cohort of 1,371 consecutive OSAS patients and 611 non-OSAS control patients in order to explore the risk factor associations and their correlation with OSAS comorbidities. To this end, we construct the Apnea Patients Network (APN) using patient compatibility relationships according to six objective parameters: age, gender, body mass index (BMI), blood pressure (BP), neck circumference (NC) and the Epworth sleepiness score (ESS)...
2017: PeerJ
https://www.readbyqxmd.com/read/28459618/an-american-thoracic-society-national-heart-lung-and-blood-institute-workshop-report-addressing-respiratory-health-equality-in-the-united-states
#2
Juan C Celedón, Esteban G Burchard, Dean Schraufnagel, Carlos Castillo-Salgado, Marc Schenker, John Balmes, Enid Neptune, Kristin J Cummings, Fernando Holguin, Kristin A Riekert, Juan P Wisnivesky, Joe G N Garcia, Jesse Roman, Rick Kittles, Victor E Ortega, Susan Redline, Rasika Mathias, Al Thomas, Jonathan Samet, Jean G Ford
Health disparities related to race, ethnicity, and socioeconomic status persist and are commonly encountered by practitioners of pediatric and adult pulmonary, critical care, and sleep medicine in the United States. To address such disparities and thus progress toward equality in respiratory health, the American Thoracic Society and the National Heart, Lung, and Blood Institute convened a workshop in May of 2015. The workshop participants addressed health disparities by focusing on six topics, each of which concluded with a panel discussion that proposed recommendations for research on racial, ethnic, and socioeconomic disparities in pulmonary, critical care, and sleep medicine...
May 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28289446/continuing-professional-development-introducing-the-ers-international-certificate-in-respiratory-sleep-medicine
#3
EDITORIAL
Sharon Mitchell, Renata L Riha, Gernot Rohde, Anita K Simonds
Certification of specialists in respiratory sleep medicine for the purposes of continuing professional development http://ow.ly/4uX9309g3Hs.
March 2017: Breathe
https://www.readbyqxmd.com/read/28282995/understanding-copd-overlap-syndromes
#4
Tuang Yeow Poh, Micheál Mac Aogáin, Adrian Kwok Wai Chan, Anthony Chau Ang Yii, Valerie Fei Lee Yong, Pei Yee Tiew, Mariko Siyue Koh, Sanjay Haresh Chotirmall
Chronic obstructive pulmonary disease accounts for a large burden of lung disease. It can 'overlap' with other respiratory diseases including bronchiectasis, fibrosis and obstructive sleep apnea (OSA). While COPD alone confers morbidity and mortality, common features with contrasting clinical outcomes can occur in COPD 'overlap syndromes'. Areas covered: Given the large degree of heterogeneity in COPD, individual variation to treatment is adopted based on its observed phenotype, which in turn overlaps with features of other respiratory disease states such as asthma...
April 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28225162/mandibular-position-and-movements-suitability-for-diagnosis-of-sleep-apnoea
#5
Jean-Benoit Martinot, Jean-Christian Borel, Valérie Cuthbert, Hervé Jean-Pierre Guénard, Stéphane Denison, Philip E Silkoff, David Gozal, Jean-Louis Pepin
BACKGROUND AND OBJECTIVE: Mandibular movements (MMs) and position during sleep reflect respiratory efforts related to increases in upper airway resistance and micro-arousals. The study objective was to assess whether MM identifies sleep-disordered breathing (SDB) in patients with moderate to high pre-test probability. METHODS: This was a prospective study of 87 consecutive patients referred for an in-laboratory sleep test. Magnetometer-derived MM signals were incorporated into standard polysomnography (PSG)...
April 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28222476/-positionpaper-on-telemonitoring-in-sleep-related-breathing-disorders
#6
W Randerath, M Bögel, C Franke, A Hellmann, B Jany, G Nilius, T Penzel, T Voshaar, A Wiater
The use of telemonitoring in the care of patients with Sleep-related Breathing Disorders (SBD) can enhance medical support significantly. Telemonitoring aims at helping physicians to detect therapy problems early and thus improve patients' therapy adherence. Diagnostics and therapy decisions in the telemonitoring process nevertheless remain the responsibility of sleep specialists. The selection of data monitored, their evaluation and resulting consequences fall to the physician, who makes decisions and prescribes therapy in consultation with the patient...
February 2017: Pneumologie
https://www.readbyqxmd.com/read/28210309/my-night-on-call-in-poland
#7
Patrycja Rzepka-Wrona
I am a young doctor who graduated from the Medical University of Silesia in 2014. After 13 months of postgraduate training, passing a state examination and successful completion of the admission process I made a decision to specialise in Respiratory Medicine. I started working in a large clinical hospital that provides junior doctors with excellent opportunities for training and career development. The respiratory unit is highly specialised and deals with sleep-related medical problems, interstitial lung diseases and respiratory failure, which may be treated using noninvasive mechanical ventilation...
September 2016: Breathe
https://www.readbyqxmd.com/read/28145229/sleep-apnoea-and-driving-more-clarity-needed
#8
EDITORIAL
The Lancet Respiratory Medicine
No abstract text is available yet for this article.
February 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28121644/peripartum-management-of-obstructive-sleep-apnea
#9
Jessica M Booth, Ashley M Tonidandel
The prevalence of obstructive sleep apnea is unknown during pregnancy, but the syndrome is likely underdiagnosed and rising in frequency along with the obesity epidemic. Obstructive sleep apnea is associated with adverse outcomes, including hypertensive disorders of pregnancy, gestational diabetes, preterm, and cesarean delivery. Obese pregnant women should be screened and referred to a sleep medicine specialist for evaluation. Continuous positive airway pressure is the treatment of choice with demonstrated safety and compliance in pregnancy...
June 2017: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28093442/rococo-study-a-real-world-evaluation-of-an-over-the-counter-medicine-in-acute-cough-a-multicentre-randomised-controlled-study
#10
S S Birring, J Brew, A Kilbourn, V Edwards, R Wilson, A H Morice
OBJECTIVES: To investigate the efficacy and safety of CS1002, an over-the-counter cough treatment containing diphenhydramine, ammonium chloride and levomenthol in a cocoa-based demulcent. DESIGN: A multicentre, randomised, parallel group, controlled, single-blinded study in participants with acute upper respiratory tract infection-associated cough. SETTING: 4 general practitioner (GP) surgeries and 14 pharmacies in the UK. PARTICIPANTS: Participants aged ≥18 years who self-referred to a GP or pharmacist with acute cough of <7 days' duration...
January 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/27916076/-daytime-hypercapnia-in-patients-with-obstructive-sleep-apnea-hypopnea-syndrome-in-han-and-uygur-nationality
#11
Z M He, X L Jiang, Piliqing Da, Z Ye, J P Li, Q L Zhang, Y Chen, J Shi, M Li, F Han
Objective: To evaluate the incidence and factors related to daytime hypercapnia in Han and Uygur patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: There were 221 patients with OSAHS (include 179 Han patients and 42 Uygur patients) in Sleep Center of Department of Respiratory and Critical Care Medicine of Karamay Central Hospital from 2015, Jan to Dec. All the patients underwent polysomnography (PSG), nocturnal oximetry, daytime blood gas analysis, pulmonary function test and Mouth occlusion pressure (P0...
November 29, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27890390/world-association-of-sleep-medicine-wasm-2016-standards-for-recording-and-scoring-leg-movements-in-polysomnograms-developed-by-a-joint-task-force-from-the-international-and-the-european-restless-legs-syndrome-study-groups-irlssg-and-eurlssg
#12
R Ferri, S Fulda, R P Allen, M Zucconi, O Bruni, S Chokroverty, L Ferini-Strambi, B Frauscher, D Garcia-Borreguero, M Hirshkowitz, B Högl, Y Inoue, A Jahangir, M Manconi, C L Marcus, D L Picchietti, G Plazzi, J W Winkelman, R S Zak
This report presents the results of the work by a joint task force of the International and European Restless Legs Syndrome Study Groups and World Association of Sleep Medicine that revised and updated the current standards for recording and scoring leg movements (LM) in polysomnographic recordings (PSG). First, the background of the decisions made and the explanations of the new rules are reported and then specific standard rules are presented for recording, detecting, scoring and reporting LM activity in PSG...
October 2016: Sleep Medicine
https://www.readbyqxmd.com/read/27861433/understanding-phenotypes-of-obstructive-sleep-apnea-applications-in-anesthesia-surgery-and-perioperative-medicine
#13
Yamini Subramani, Mandeep Singh, Jean Wong, Clete A Kushida, Atul Malhotra, Frances Chung
Obstructive sleep apnea (OSA) is a prevalent sleep-disordered breathing with potential long-term major neurocognitive and cardiovascular sequelae. The pathophysiology of OSA varies between individuals and is composed of different underlying mechanisms. Several components including the upper airway anatomy, effectiveness of the upper airway dilator muscles such as the genioglossus, arousal threshold of the individual, and inherent stability of the respiratory control system determine the pathogenesis of OSA...
January 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27855739/validation-of-polyvinylidene-fluoride-impedance-sensor-for-respiratory-event-classification-during-polysomnography-in-children
#14
Anne G Griffiths, Pallavi P Patwari, Darius A Loghmanee, Matthew J Balog, Irina Trosman, Stephen H Sheldon
STUDY OBJECTIVES: Polysomnography is the gold standard for diagnosis and characterization of severity of sleep-disordered breathing. Accuracy and reliability of the technology used are critical to the integrity of the study's interpretation. Strict criteria for obstructive sleep apnea in children are lacking and diagnosis often requires consideration of frequency of respiratory events in addition to other measures. Current American Academy of Sleep Medicine recommendations for pediatric patients includes use of respiratory inductance plethysmography (RIP) belts, whereas polyvinylidene fluoride (PVDF) belts are currently only acceptable for use in adults...
February 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27826247/modulations-of-heart-rate-ecg-and-cardio-respiratory-coupling-observed-in-polysomnography
#15
REVIEW
Thomas Penzel, Jan W Kantelhardt, Ronny P Bartsch, Maik Riedl, Jan F Kraemer, Niels Wessel, Carmen Garcia, Martin Glos, Ingo Fietze, Christoph Schöbel
The cardiac component of cardio-respiratory polysomnography is covered by ECG and heart rate recordings. However, their evaluation is often underrepresented in summarizing reports. As complements to EEG, EOG, and EMG, these signals provide diagnostic information for autonomic nervous activity during sleep. This review presents major methodological developments in sleep research regarding heart rate, ECG, and cardio-respiratory couplings in a chronological (historical) sequence. It presents physiological and pathophysiological insights related to sleep medicine obtained by new technical developments...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27793516/-overnight-polysomnography-versus-respiratory-polygraphy-in-the-diagnosis-of-pediatric-obstructive-sleep-apnea
#16
P Franco, H Bourdin, F Braun, J Briffod, I Pin, M-J Challamel
The French Society of Research and Sleep Medicine (SFRMS) organized a meeting on obstructive sleep apnea syndrome (OSAS) in children. A multidisciplinary group of specialists (pulmonologists, ENT surgeons, pediatricians, neurophysiologists, sleep specialists) drew up a consensus document on the value of electrophysiological recordings in the diagnosis of OSAS in children. Technical considerations and recommended sensors, respiratory event definitions, and scoring criteria are presented according to the 2012 and 2014 recommendations of the American Academy of Sleep Medicine (AASM)...
October 25, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27769627/-obstructive-sleep-apnea-hypopnea-syndrome-in-children-clinical-diagnosis
#17
G Aubertin, C Schröder, F Sevin, F Clouteau, M-D Lamblin, M-F Vecchierini
The French Society of Research and Sleep Medicine (SFRMS) organized a meeting on obstructive sleep apnea syndrome (OSAS) in children. A multidisciplinary group of specialists (pulmonologist, ENT surgeons, pediatricians, orofacial myofunctional therapists, neurophysiologists, and sleep specialists) reached a consensus on the value of isolated or clustered clinical symptoms and of questionnaires completed by parents in the clinical diagnosis and in assessing the severity of OSAS. Are clinical history with validated questionnaires and a rigorous physical examination sufficient to suspect OSAS, to appreciate its severity, and finally to confirm the diagnosis? Usually, a sleep recording of respiratory parameters remains mandatory for the diagnosis of OSAS to be made...
October 18, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/27761840/differences-in-sleep-architecture-between-left-and-right-temporal-lobe-epilepsy
#18
Miki Nakamura, Kazutaka Jin, Kazuhiro Kato, Hisashi Itabashi, Masaki Iwasaki, Yosuke Kakisaka, Nobukazu Nakasato
To investigate whether seizure lateralization affects sleep macrostructure in patients with left and right temporal lobe epilepsy (TLE), as rapid eye movement (REM) sleep is shorter in patients with right hemispheric cerebral infarction than with left. We retrospectively analyzed data from 16 patients with TLE (6 men and 10 women aged 34.9 ± 11.4 years) who underwent polysomnography as well as long-term video electroencephalography. Ten patients were diagnosed with left TLE and six patients with right TLE...
January 2017: Neurological Sciences
https://www.readbyqxmd.com/read/27647717/codeine-time-to-say-no
#19
Joseph D Tobias, Thomas P Green, Charles J Coté
Codeine has been prescribed to pediatric patients for many decades as both an analgesic and an antitussive agent. Codeine is a prodrug with little inherent pharmacologic activity and must be metabolized in the liver into morphine, which is responsible for codeine's analgesic effects. However, there is substantial genetic variability in the activity of the responsible hepatic enzyme, CYP2D6, and, as a consequence, individual patient response to codeine varies from no effect to high sensitivity. Drug surveillance has documented the occurrence of unanticipated respiratory depression and death after receiving codeine in children, many of whom have been shown to be ultrarapid metabolizers...
October 2016: Pediatrics
https://www.readbyqxmd.com/read/27634793/polysomnography-in-bolivian-children-native-to-high-altitude-compared-to-children-native-to-low-altitude
#20
Catherine Mary Hill, Annette Carroll, Dagmara Dimitriou, Johanna Gavlak, Kate Heathcote, Veline L'Esperance, Ana Baya, Rebecca Webster, Maria Pushpanathan, Romola Starr Bucks
STUDY OBJECTIVES: To compare polysomnographic parameters in high altitude (HA) native Andean children with low altitude (LA) native peers in order to explain the nocturnal oxyhemoglobin saturation (SpO2) instability reported in HA native children and to study the effect on sleep quality. METHODS: Ninety-eight healthy children aged 7-10 y and 13-16 y were recruited at LA (500 m) or HA (3,650 m) above sea level. Physical examination was undertaken and genetic ancestry determined from salivary DNA to determine proportion of European ancestry, a risk factor for poor HA adaptation...
December 1, 2016: Sleep
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