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Major depression and mortality

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https://www.readbyqxmd.com/read/28209152/municipal-resources-and-patient-outcomes-through-the-first-year-after-a-hip-fracture
#1
Sabine Ruths, Valborg Baste, Marit Stordal Bakken, Lars Birger Engesæter, Stein Atle Lie, Siren Haugland
BACKGROUND: Hip fractures represent major critical events for older people, and put huge demands on economic and personnel resources. Most hip fracture patients are in need of postoperative rehabilitation services. Through the Coordination Reform, the municipalities in Norway were given increased responsibility for community-based treatment and rehabilitation after surgery. The purpose of this study was to examine associations between municipal resources and patient outcomes through the first year after a hip fracture, focusing on survival and health-related quality of life...
February 16, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28204860/left-ventricular-systolic-dysfunction-during-septic-shock-the-role-of-loading-conditions
#2
Florence Boissier, Keyvan Razazi, Aurélien Seemann, Alexandre Bedet, Arnaud W Thille, Nicolas de Prost, Pascal Lim, Christian Brun-Buisson, Armand Mekontso Dessap
PURPOSE: The clinical significance of septic myocardial dysfunction is controversial, a fact that may be explained by the influence of loading conditions. Many indices may be useful to characterize cardiac function during septic shock, but their feasibility and physiological coherence in the clinical setting are unknown. METHODS: Hemodynamic and echocardiographic data with tissue Doppler and speckle tracking were prospectively recorded on the first 3 days of human septic shock...
February 15, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28202089/suicidal-ideation-and-behaviour-among-community-and-health-care-seeking-populations-in-five-low-and-middle-income-countries-a-cross-sectional-study
#3
M Jordans, S Rathod, A Fekadu, G Medhin, F Kigozi, B Kohrt, N Luitel, I Petersen, R Shidhaye, J Ssebunnya, V Patel, C Lund
: Aims Suicidal behaviour is an under-reported and hidden cause of death in most low- and middle-income countries (LMIC) due to lack of national systematic reporting for cause-specific mortality, high levels of stigma and religious or cultural sanctions. The lack of information on non-fatal suicidal behaviour (ideation, plans and attempts) in LMIC is a major barrier to design and implementation of prevention strategies. This study aims to determine the prevalence of non-fatal suicidal behaviour within community- and health facility-based populations in LMIC...
February 16, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28197877/fasting-leptin-and-glucose-in-normal-weight-over-weight-and-obese-men-and-women-diabetes-patients-with-and-without-clinical-depression
#4
Darakhshan Jabeen Haleem, Shehnaz Sheikh, Asher Fawad, Muhammad A Haleem
A large number of diabetes patients suffer from major depression and are at high risk of mortality. In view of a role of leptin in diabetes, depression and energy homeostasis, the present study concerns circulating levels of leptin in different BMI groups of un-depressed and depressed diabetes patients. Six hundred thirty male and female patients with a primary diagnosis of diabetes were grouped according to BMI and with or without clinical symptoms of depression. Age matched healthy, normal weight male and female volunteers without clinical symptoms of depression or diabetes were taken as controls...
February 15, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28166611/health-related-quality-of-life-in-idiopathic-pulmonary-fibrosis-data-from-the-australian-ipf-registry
#5
Ian N Glaspole, Sally A Chapman, Wendy A Cooper, Samantha J Ellis, Nicole S Goh, Peter M Hopkins, Sacha Macansh, Annabelle Mahar, Yuben P Moodley, Eldho Paul, Paul N Reynolds, E Haydn Walters, Christopher J Zappala, Tamera J Corte
BACKGROUND AND OBJECTIVE: Studies analysing the effect of worsening pulmonary physiological impairment in idiopathic pulmonary fibrosis (IPF) with respect to quality of life have been limited to single centres or highly selected trial populations. The aim of this study was to determine the principal determinants of baseline and longitudinal health-related quality of life (HRQoL) in a large unselected IPF population. METHODS: We used the Australian IPF Registry to examine the relationship between HRQoL, measured using the St George Respiratory Questionnaire (SGRQ), and demographic features, physiological features, co-morbidities and symptoms...
February 6, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28163834/does-heart-rate-variability-correlate-with-long-term-prognosis-in-myocardial-infarction-patients-treated-by-early-revascularization
#6
Leonida Compostella, Nenad Lakusic, Caterina Compostella, Li Van Stella Truong, Sabino Iliceto, Fabio Bellotto
AIM: To assess the prevalence of depressed heart rate variability (HRV) after an acute myocardial infarction (MI), and to evaluate its prognostic significance in the present era of immediate reperfusion. METHODS: Time-domain HRV (obtained from 24-h Holter recordings) was assessed in 326 patients (63.5 ± 12.1 years old; 80% males), two weeks after a complicated MI treated by early reperfusion: 208 ST-elevation myocardial infarction (STEMI) patients (in which reperfusion was successfully obtained within 6 h of symptoms in 94% of cases) and 118 non-ST-elevation myocardial infarction (NSTEMI) patients (percutaneous coronary intervention was performed within 24 h and successful in 73% of cases)...
January 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28160185/diabetes-distress-or-major-depressive-disorder-a-practical-approach-to-diagnosing-and-treating-psychological-comorbidities-of-diabetes
#7
Kathryn Evans Kreider
The presence of major depressive disorder (MDD) in people with diabetes may be up to three times more common than in the general population. People with diabetes and major depressive disorder have worse health outcomes and higher mortality rates. Diabetes distress refers to an emotional state where people experience feelings such as stress, guilt, or denial that arise from living with diabetes and the burden of self-management. Diabetes distress has also been linked to worse health outcomes. There are multiple treatment options for MDD including pharmacotherapy and cognitive behavioral approaches...
February 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28156569/differences-in-self-care-behaviors-by-varying-levels-of-caregiving-intensity-performance-and-well-being-among-family-caregivers-of-patients-with-high-mortality-cancer
#8
Wendy Demark-Wahnefried, Richard A Taylor, Gabrielle Betty Rocque, Andres Azuero, Aras Acemgil, Michelle Y Martin, Meka Astin, Deborah Ejem, Elizabeth Ann Kvale, Karen Heaton, Maria Pisu, Edward E Partridge, Marie Bakitas
: 239 Background: Family caregivers of high-mortality cancer patients perform vital tasks that deter from their own self-care. We aimed to determine differences in self-care behaviors by varying levels of caregiving intensity, well-being, and performance. METHODS: Cross-sectional survey conducted in community settings of 8 cancer centers in AL, FL, and TN. Two-hundred and ninety-four family caregivers of Medicare beneficiaries diagnosed with pancreatic, lung, brain, ovarian, head & neck, hematologic, or stage IV cancer completed measures of self-care behaviors, including health responsibility, physical activity, nutrition, spiritual growth, interpersonal relations, stress management, and sleep; anxiety and depression; health-related quality of life (HRQoL); caregiver competence and preparedness; and decision-making self-efficacy...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156553/are-families-the-barrier-evaluating-attitudes-toward-early-integration-of-palliative-care-in-pediatric-hematopoietic-stem-cell-transplant
#9
Justin N Baker
: 112 Background: The benefits of early integration of palliative care (PC) in oncology have been well established yet, there remain significant barriers to PC integration, especially in the setting of pediatric hematopoietic stem cell transplant (HSCT). HSCT patients are prone to a great degree of treatment related toxicity and are at high risk for morbidity and mortality and, while ideally suited to benefit, inherent factors in this cure oriented field preclude the integration of PC services...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28154539/temporal-association-of-certain-neuropsychiatric-disorders-following-vaccination-of-children-and-adolescents-a-pilot-case-control-study
#10
Douglas L Leslie, Robert A Kobre, Brian J Richmand, Selin Aktan Guloksuz, James F Leckman
BACKGROUND: Although the association of the measles, mumps, and rubella vaccine with autism spectrum disorder has been convincingly disproven, the onset of certain brain-related autoimmune and inflammatory disorders has been found to be temporally associated with the antecedent administration of various vaccines. This study examines whether antecedent vaccinations are associated with increased incidence of obsessive-compulsive disorder (OCD), anorexia nervosa (AN), anxiety disorder, chronic tic disorder, attention deficit hyperactivity disorder, major depressive disorder, and bipolar disorder in a national sample of privately insured children...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28152886/impact-of-precancer-multimorbidity-clusters-on-survival-and-functional-outcomes-after-cancer-in-older-patients
#11
Joshua Richman, Erin E Kent, Maria Pisu, Smita Bhatia
: 291 Background: While multimorbidity clustering is a significant problem in older adults, the impact of clusters present prior to cancer on post-diagnosis survival and function is unknown. We used SEER-Medicare Health Outcomes Survey data for 4583 cancer patients to address this research gap. METHODS: Patients with prostate (1741), breast (BC: 1345), colorectal (CRC: 904) and lung (593) cancer with pre- and post-diagnosis survey data were included. Surveys assessed comorbidity and activities of daily living (ADLs)...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152638/are-vasopressors-useful-in-toxin-induced-cardiogenic-shock
#12
Cassandra A Skoog, Kristin M Engebretsen
OBJECTIVE: Overdoses with cardio-depressive medications can result in toxin-induced cardiogenic shock (TICS), a life-threatening condition characterized by severe hypotension and ineffective tissue perfusion. Vasopressors are often employed in the treatment of shock to increase heart rate and blood pressure. We sought to conduct a systematic review of the literature to evaluate the effectiveness of vasopressors in improving hemodynamic function and survival in the treatment of TICS. DATA SOURCES: We searched PubMed, EMBASE, TOXLINE, and International Pharmaceutical Abstracts...
February 3, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28132777/reduced-muscle-mass-in-middle-aged-depressed-patients-is-associated-with-male-gender-and-chronicity
#13
Kai G Kahl, Ferdi Utanir, Ulrich Schweiger, Tillmann H Krüger, Helge Frieling, Stefan Bleich, Marcel Gutberlet, Dagmar Hartung
OBJECTIVE: Reduced muscle mass is a characteristic finding in sarcopenia, the central element of physical frailty syndrome, and a major cause of physical function decay, morbidity and mortality in the elderly. Studies so far demonstrated reduced muscle mass in depressed patients with an average age over 60years.An open question is whether muscle mass reduction is already observed earlier. Therefore, muscle mass was assessed in middle-aged male and female depressive patients, and the findings were related to indicators of hypothalamus-pituitary adrenal axis activation, lifestyle factors, endocrine and immune measures...
January 26, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28129313/clinical-outcomes-of-concomitant-use-of-warfarin-and-selective-serotonin-reuptake-inhibitors-a-multidatabase-observational-cohort-study
#14
Yaa-Hui Dong, Katsiaryna Bykov, Niteesh K Choudhry, Macarius M Donneyong, Krista F Huybrechts, Raisa Levin, Sebastian Schneeweiss, Joshua J Gagne
BACKGROUND: Patients treated with warfarin are often coprescribed selective serotonin reuptake inhibitors (SSRIs) for coexisting depression. Some SSRIs are potent CYP2C9 inhibitors that may increase warfarin plasma concentrations and the risk of bleeding. We aimed to examine the effect of the putative CYP2C9-mediated warfarin-SSRI interaction on clinical outcomes. METHODS: We conducted an observational cohort study among warfarin initiators who had a subsequent SSRI prescription in 5 US claims databases...
January 26, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28125166/depression-and-religiosity-and-their-correlates-in-lebanese-breast-cancer-patients
#15
Sandra Abou Kassm, Sani Hlais, Christina Khater, Issam Chehade, Ramzi Haddad, Johnny Chahine, Mohammad Yazbeck, Rita Abi Warde, Wadih Naja
OBJECTIVE: Breast cancer bears considerable morbidity and mortality and is well known to increase the risk of major depression, whereas religiosity has been reported to be protective. We searched for an association between depression and religiosity in breast cancer patients. We also sought to find an association between depression and various socio-demographic and disease variables. METHODS: 102 patients were interviewed. Socio-demographic, cancer profile and religiosity questionnaires were administered...
January 26, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28120427/oral-anti-diabetic-pharmacological-therapies-for-the-treatment-of-women-with-gestational-diabetes
#16
REVIEW
Julie Brown, Ruth Martis, Brenda Hughes, Janet Rowan, Caroline A Crowther
BACKGROUND: Gestational diabetes mellitus (GDM) is a major public health issue with rates increasing globally. Gestational diabetes, glucose intolerance first recognised during pregnancy, usually resolves after birth and is associated with short- and long-term complications for the mother and her infant. Treatment options can include oral anti-diabetic pharmacological therapies. OBJECTIVES: To evaluate the effects of oral anti-diabetic pharmacological therapies for treating women with GDM...
January 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28077154/incremental-decreases-in-quality-adjusted-life-years-qaly-associated-with-higher-levels-of-depressive-symptoms-for-u-s-adults-aged-65-years-and-older
#17
Haomiao Jia, Erica I Lubetkin
BACKGROUND: Quality-adjusted life years (QALY) is a single value index that quantifies the overall burden of disease. It reflects all aspects of heath, including nonfatal illness and mortality outcomes by weighting life-years lived with health-related quality of life (HRQOL) scores. This study examine the burden of disease due to increasing levels of depressive symptoms by examining the association between the 9-item Patient Health Questionnaire (PHQ-9) scores and QALY for U.S. adults aged 65 years and older...
January 11, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28076632/-emma-study-a-brazilian-community-based-cohort-study-of-stroke-mortality-and-morbidity
#18
Alessandra Carvalho Goulart
CONTEXT AND OBJECTIVE: Stroke has a high burden of disability and mortality. The aim here was to evaluate epidemiology, risk factors and prognosis for stroke in the EMMA Study (Study of Stroke Mortality and Morbidity). DESIGN AND SETTINGS: Prospective community-based cohort carried out in Hospital Universitário, University of São Paulo, 2006-2014. METHODS: Stroke data based on fatal and non-fatal events were assessed, including sociodemographic data, mortality and predictors, which were evaluated by means of logistic regression and survival analyses...
November 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28063309/qualitative-and-quantitative-changes-in-phospholipids-and-proteins-investigated-by-spectroscopic-techniques-in-animal-depression-model
#19
J Depciuch, M Sowa-Kucma, G Nowak, M Papp, P Gruca, P Misztak, M Parlinska-Wojtan
Depression becomes nowadays a high mortality civilization disease with one of the major causes being chronic stress. Raman, Fourier Transform Infra Red (FTIR) and Ultraviolet-Visible (UV-vis) spectroscopies were used to determine the changes in the quantity and structure of phospholipids and proteins in the blood serum of rats subjected to chronic mild stress, which is a common animal depression model. Moreover, the efficiency of the imipramine treatment was evaluated. It was found that chronic mild stress not only damages the structure of the phospholipids and proteins, but also decreases their level in the blood serum...
December 28, 2016: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28056867/risk-factors-and-characteristics-of-blood-stream-infections-in-patients-with-newly-diagnosed-multiple-myeloma
#20
Chun-Teng Huang, Chia-Jen Liu, Po-Shen Ko, Han-Tsung Liu, Yuan-Bin Yu, Liang-Tsai Hsiao, Jyh-Pyng Gau, Cheng-Hwai Tzeng, Tzeon-Jye Chiou, Jin-Hwang Liu, Muh-Hwa Yang, Ling-Ju Huang, Chun-Yu Liu
BACKGROUND: Patients with multiple myeloma are generally immune-compromised either due to pronounced depression in primary antibody responses or because of anti-myeloma therapy. Infection is a major risk factor for early deaths among these patients. The impact of blood stream infections (BSI) on newly diagnosed myeloma patients has been less studied. We aimed to study the incidence and risk factors of BSI within 3 months after diagnosis of multiple myeloma in a tertiary referral center...
January 6, 2017: BMC Infectious Diseases
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