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Major depression and mortality

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https://www.readbyqxmd.com/read/28806633/provision-of-sudden-unexpected-death-in-epilepsy-sudep-information-among-malaysian-parents-of-children-with-epilepsy
#1
Choong Yi Fong, Wei Kang Lim, Ann Nie Kong, Pei Lin Lua, Lai Choo Ong
Sudden unexpected death in epilepsy (SUDEP) is an important cause of mortality in epilepsy. To date, there is only one published UK study evaluating information provision of SUDEP among parents of children with epilepsy (CWE), and there are no studies published from Asia. Although SUDEP information provision is recommended among parents of CWE, it is uncertain if these recommendations are applicable to Asian countries due to the different cultural attitude towards epilepsy. Our prospective cohort study consisted of multiethnic parents of children with epilepsy (CWE) seen in a tertiary hospital in Malaysia...
August 11, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28796415/white-matter-tract-integrity-is-associated-with-antidepressant-response-to-lurasidone-in-bipolar-depression
#2
Martin J Lan, Harry Rubin-Falcone, Fatima Motiwala, Ying Chen, Jonathan W Stewart, David J Hellerstein, J John Mann, Patrick J McGrath
OBJECTIVES: Patients with bipolar disorder spend the most time in the depressed phase, and that phase is associated with the most morbidity and mortality. Treatment of bipolar depression lacks a test to determine who will respond to treatment. White matter disruptions have been found in bipolar disorder. Previous reports suggest that white matter disruptions may be associated with resistance to antidepressant medication, but this has never been investigated in a prospective study using a Food and Drug Administration (FDA)-approved medication...
August 10, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28781755/what-do-hypnotics-cost-hospitals-and-healthcare
#3
Daniel F Kripke
Hypnotics (sleeping pills) are prescribed widely, but the economic costs of the harm they have caused have been largely unrecognized. Randomized clinical trials have proven that hypnotics increase the incidence of infections. Likewise, hypnotics increase the incidence of major depression and cause emergency admissions for overdoses and deaths.  Epidemiologically, hypnotic use is associated with cancer, falls, automobile accidents, and markedly increased overall mortality.  This article considers the costs to hospitals and healthcare payers of hypnotic-induced infections and other severe consequences of hypnotic use...
2017: F1000Research
https://www.readbyqxmd.com/read/28777032/suicidal-ideation-in-an-egyptian-sample-of-hospitalized-patients-with-acute-psychosis
#4
Maha Ftouh, El-Sayed Gad, Mohammad A Seleem, Sameh Saada, Ahmed A Mubarak
BACKGROUND: Suicide mortality is 12 times higher in psychotic patients compared to the general population. Identifying characteristic of suicidal patients among this group might help in preventing such behavior. AIMS: To assess the predictors of suicidal risk in patients hospitalized due to acute psychosis. METHODS: One hundred and fifty patients (age 18 - 60 years) admitted with acute psychotic features were recruited. Patients were evaluated clinically by The Arabic version of Mini International Neuropsychiatric Interview (M...
August 4, 2017: Clinical Schizophrenia & related Psychoses
https://www.readbyqxmd.com/read/28765710/cost-utility-of-collaborative-care-for-the-treatment-of-comorbid-major-depressive-disorder-in-outpatients-with-chronic-physical-conditions-a-randomized-controlled-trial-in-the-general-hospital-setting-cc-dim
#5
Maartje Goorden, Christina M van der Feltz-Cornelis, Kirsten M van Steenbergen-Weijenburg, Eva K Horn, Aartjan Tf Beekman, Leona Hakkaart-van Roijen
PURPOSE: Major depressive disorder (MDD) is highly prevalent in patients with a chronic physical condition, and this comorbidity has a negative influence on quality of life, health care costs, self-care, morbidity, and mortality. Research has shown that collaborative care (CC) may be a cost-effective treatment. However, its cost-effectiveness in this patient group has not yet been established. Therefore, the aim of this study was to evaluate the cost-utility of CC for the treatment of comorbid MDD in chronically ill patients in the outpatient general hospital setting...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28764654/association-of-restless-legs-syndrome-and-mortality-in-end-stage-renal-disease-an-analysis-of-the-united-states-renal-data-system-usrds
#6
Joseph J DeFerio, Usha Govindarajulu, Amarpali Brar, Daniel Cukor, Kathleen G Lee, Moro O Salifu
BACKGROUND: Objective of the study is to assess prevalence and survival among end stage renal disease patients with restless legs syndrome (RLS) within a national database (USRDS). METHODS: A case-control, retrospective analysis was performed. Differences in characteristics between the groups, RLS and those with no sleep disorder (NSD), were determined using χ2 tests. Cox proportional hazard regression was used to assess survival between those with RLS and propensity score matched controls...
August 1, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28754123/post-mortem-molecular-profiling-of-three-psychiatric-disorders
#7
Ryne C Ramaker, Kevin M Bowling, Brittany N Lasseigne, Megan H Hagenauer, Andrew A Hardigan, Nicholas S Davis, Jason Gertz, Preston M Cartagena, David M Walsh, Marquis P Vawter, Edward G Jones, Alan F Schatzberg, Jack D Barchas, Stanley J Watson, Blynn G Bunney, Huda Akil, William E Bunney, Jun Z Li, Sara J Cooper, Richard M Myers
BACKGROUND: Psychiatric disorders are multigenic diseases with complex etiology that contribute significantly to human morbidity and mortality. Although clinically distinct, several disorders share many symptoms, suggesting common underlying molecular changes exist that may implicate important regulators of pathogenesis and provide new therapeutic targets. METHODS: We performed RNA sequencing on tissue from the anterior cingulate cortex, dorsolateral prefrontal cortex, and nucleus accumbens from three groups of 24 patients each diagnosed with schizophrenia, bipolar disorder, or major depressive disorder, and from 24 control subjects...
July 28, 2017: Genome Medicine
https://www.readbyqxmd.com/read/28746904/prophylactic-antidepressant-treatment-following-acute-coronary-syndrome-a-systematic-review-of-randomized-controlled-trials
#8
REVIEW
Ole G Christiansen, Michael T Madsen, Erik Simonsen, Ismail Gögenur
Major depressive disorder is significantly increased in patients following acute coronary syndrome resulting in twofold increased mortality compared with patients without depression. The depression diagnosis is often missed leading to considerable undertreatment. This systematic review assesses the current evidence of primary prophylactic treatment of depression in patients after acute coronary syndrome. The study protocol was prospectively registered at PROSPERO (registration number CRD42015025587). A systematic review were conducted and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines...
July 19, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28746360/synergistic-effects-of-cognitive-impairment-on-physical-disability-in-all-cause-mortality-among-men-aged-80-years-and-over-results-from-longitudinal-older-veterans-study
#9
Wan-Chen Yu, Ming-Yueh Chou, Li-Ning Peng, Yu-Te Lin, Chih-Kuang Liang, Liang-Kung Chen
OBJECTIVE: We evaluated effects of the interrelationship between physical disability and cognitive impairment on long-term mortality of men aged 80 years and older living in a retirement community in Taiwan. METHODS: This prospective cohort study enrolled older men aged 80 and older living in a Veterans Care Home. Those with confirmed diagnosis of dementia were excluded. All participants received comprehensive geriatric assessment, including sociodemographic data, Charlson's Comorbidity Index (CCI), geriatric syndromes, activities of daily living (ADL) using the Barthel index and cognitive function using the Mini-Mental State Examination (MMSE)...
2017: PloS One
https://www.readbyqxmd.com/read/28738686/disparities-in-diabetes-and-hypertension-care-for-individuals-with-serious-mental-illness
#10
Junqing Liu, Jonathan Brown, Suzanne Morton, D E B Potter, Lisa Patton, Milesh Patel, Rita Lewis, Sarah Hudson Scholle
OBJECTIVES: People with serious mental illnesses (SMI), including schizophrenia, bipolar disorder, and major depression, experience early mortality, partly due to comorbid physical health conditions such as diabetes and hypertension. This study examined the quality of diabetes and hypertension care for Medicaid and Medicare enrollees with SMI. STUDY DESIGN: We conducted a retrospective analysis of medical records and claims data from 3 health plans: a Medicaid plan for disabled adults, a Medicaid plan for low-income adults, and a Special Needs Plan for individuals dually enrolled in Medicaid and Medicare...
May 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28736506/national-disability-adjusted-life-years-dalys-for-257-diseases-and-injuries-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#11
Awoke Misganaw, Yohannes Adama Melaku, Gizachew Assefa Tessema, Amare Deribew, Kebede Deribe, Semaw Ferede Abera, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Tilahun N Haregu, Azmeraw T Amare, Molla Gedefaw, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Tom Achoki, Jed Blore, Kristopher J Krohn, Yibeltal Assefa, Mahlet Kifle, Mohsen Naghavi
BACKGROUND: Disability-adjusted life years (DALYs) provide a summary measure of health and can be a critical input to guide health systems, investments, and priority-setting in Ethiopia. We aimed to determine the leading causes of premature mortality and disability using DALYs and describe the relative burden of disease and injuries in Ethiopia. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) for non-fatal disease burden, cause-specific mortality, and all-cause mortality to derive age-standardized DALYs by sex for Ethiopia for each year...
2017: Population Health Metrics
https://www.readbyqxmd.com/read/28732542/national-disability-adjusted-life-years-dalys-for-257-diseases-and-injuries-in-ethiopia-1990-2015-findings-from-the-global-burden-of-disease-study-2015
#12
Awoke Misganaw, Yohannes Adama Melaku, Gizachew Assefa Tessema, Amare Deribew, Kebede Deribe, Semaw Ferede Abera, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Tilahun N Haregu, Azmeraw T Amare, Molla Gedefaw, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Tom Achoki, Jed Blore, Kristopher J Krohn, Yibeltal Assefa, Mahlet Kifle, Mohsen Naghavi
BACKGROUND: Disability-adjusted life years (DALYs) provide a summary measure of health and can be a critical input to guide health systems, investments, and priority-setting in Ethiopia. We aimed to determine the leading causes of premature mortality and disability using DALYs and describe the relative burden of disease and injuries in Ethiopia. METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) for non-fatal disease burden, cause-specific mortality, and all-cause mortality to derive age-standardized DALYs by sex for Ethiopia for each year...
July 21, 2017: Population Health Metrics
https://www.readbyqxmd.com/read/28712433/two-year-prognosis-after-acute-coronary-syndrome-in-younger-patients-association-with-feeling-depressed-in-the-prior-year-and-bdi-ii-score-and-endothelin-1
#13
Luba Yammine, Lorraine Frazier, Nikhil S Padhye, Jennifer E Sanner, Matthew M Burg
OBJECTIVE: To examine the effects of depressive symptoms and Endothelin (ET)-1 on 2-year prognosis in younger patients with acute coronary syndrome (ACS). Depression is associated with poor post-ACS prognosis; however, few investigations have focused on younger patients. Importantly, the studies that did emphasize younger patients suggested that the influence of depression on prognosis could be more robust in younger subgroups. The particular links between depression and poor prognosis in younger patients have yet to be definitively determined...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28711464/personality-and-survival-in-older-age-the-role-of-lifestyle-behaviors-and-health-status
#14
Debora Rizzuto, Enrico Mossello, Laura Fratiglioni, Giola Santoni, Hui-Xin Wang
OBJECTIVE: We intended to assess the relationship between personality and survival in an older population and to explore the role of lifestyle behaviors and health status as potential mediators. DESIGN: Population-based cohort study. SETTING: Swedish National Study of Aging and Care in Kungsholmen, Sweden. PARTICIPANTS: 2,298 adults aged 60 or more years, without dementia or depression, followed for 11 years. MEASUREMENTS: Personality (extraversion, neuroticism, and openness) was assessed with a shortened version of the NEO-Five Factor Inventory...
June 8, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/28710030/differences-of-sympathetic-and-parasympathetic-modulation-in-major-depression
#15
Andy Schumann, Caroline Andrack, Karl-Jürgen Bär
Inconsistent results have been reported with respect to cardiac autonomic function in major depression. The aim of our study was to investigate autonomic function in various branches of the autonomic nervous system in order to better understand parasympathetic and sympathetic modulation in the disease. We investigated 29 unmedicated patients suffering from major depression (MD) in comparison to matched control subjects (gender, age, BMI). The autonomic assessment at rest included values of heart rate variability (HRV), blood pressure variability (BPV), baroreflex sensitivity (BRS), respiration, skin conductance (SC) as well as the calculation of pupillary diameter and the unrest index (PUI)...
July 12, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28695256/anomalously-high-recruitment-of-the-2010-gulf-menhaden-brevoortia-patronus-year-class-evidence-of-indirect-effects-from-the-deepwater-horizon-blowout-in-the-gulf-of-mexico
#16
Jeffrey W Short, Harold J Geiger, J Christopher Haney, Christine M Voss, Maria L Vozzo, Vincent Guillory, Charles H Peterson
Gulf menhaden (Brevoortia patronus) exhibited unprecedented juvenile recruitment in 2010 during the year of the Deepwater Horizon well blowout, exceeding the prior 39-year mean by more than four standard deviations near the Mississippi River. Abundance of that cohort remained exceptionally high for two subsequent years as recruits moved into older age classes. Such changes in this dominant forage fish population can be most parsimoniously explained as consequences of release from predation. Contact with crude oil induced high mortality of piscivorous seabirds, bottlenose dolphin (Tursiops truncatus), waders, and other fish-eating marsh birds, all of which are substantial consumers of Gulf menhaden...
July 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28682954/acute-intracardiac-thrombosis-and-pulmonary-thromboembolism-after-cardiopulmonary-bypass-a-systematic-review-of-reported-cases
#17
Brittney Williams, Brody Wehman, Michael A Mazzeffi, Patrick Odonkor, Ryan L Harris, Zachary Kon, Kenichi A Tanaka
Intracardiac thrombosis (ICT) and pulmonary thromboembolism (PE) after cardiopulmonary bypass (CPB) are life-threatening events, but pathological mechanisms are not yet well defined. The aim of this review is to provide an update of case literature of a postbypass hypercoagulable state. Case commonalities among 48 ICT/PE events included congestive heart failure (50%), platelet transfusion (37.5%), CPB duration greater than 3 hours (37.5%), and aortic injury (27.1%). Preexisting thrombophilia was rarely reported, and 16...
July 4, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28681620/the-burden-of-mood-disorder-cerebrovascular-disease-comorbidity-essential-neurobiology-psychopharmacology-and-physical-activity-interventions
#18
Michele Fornaro, Marco Solmi, Nicola Veronese, Domenico De Berardis, Elisabetta Filomena Buonaguro, Carmine Tomasetti, Giampaolo Perna, Antonio Preti, Mauro Giovanni Carta
Cardio-vascular diseases (CVDs) and CVD-related disorders (including cerebrovascular diseases; CBVDs) are a major public health concern as they represent the leading cause of mortality and morbidity in developed countries. Patients with CVDs and CBVDs co-morbid with mood disorders, especially bipolar disorder (BD) and major depressive disorder (MDD), suffer reduced quality-of-life and significant disability adjusted for years of life and mortality. The relationship between CVDs/CBVDs and mood disorders is likely to be bidirectional...
July 6, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28676432/pathophysiological-mechanisms-involved-in-the-relationship-between-diabetes-and-major-depressive-disorder
#19
REVIEW
Gislaine Z Réus, Maria Augusta B Dos Santos, Ana Paula Strassi, Helena M Abelaira, Luciane B Ceretta, João Quevedo
Diabetes mellitus (DM) and major depressive disorder (MDD) are diseases that are expanding globally. Separately, each presents with several comorbidities for patients. When the two diseases present simultaneously in the same subject, there is a drastic worsening in the quality of life of the patient. This study reviewed the literature relating to the relationship between MDD and DM, bringing forward studies showing that DM develops due to MDD, and others that report the opposite. According to the studies reviewed, DM and MDD are both debilitating conditions that are associated with significant morbidity, mortality, and healthcare costs...
August 15, 2017: Life Sciences
https://www.readbyqxmd.com/read/28665160/use-of-complementary-traditional-chinese-medicines-by-adult-cancer-patients-in-taiwan-a-nationwide-population-based-study
#20
Yi-Ting Kuo, Tung-Ti Chang, Chih-Hsin Muo, Mei-Yao Wu, Mao-Feng Sun, Chia-Chou Yeh, Hung-Rong Yen
BACKGROUND: Many patients with cancer seek complementary and alternative medicine treatments. We investigated the use of traditional Chinese medicine (TCM) by adult cancer patients in Taiwan. METHODS: We reviewed the Registry for Catastrophic Illness Patients Database of Taiwan, and included all adult patients diagnosed cancer, based on the International Classification of Diseases (ninth revision), from 2001 to 2009 and followed until 2011. This database allowed categorization of patients as TCM users (n = 74 620) or non-TCM users (n = 508 179)...
June 1, 2017: Integrative Cancer Therapies
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