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JOURNAL ARTICLE
Astrid Helene Deleuran Naesager, Sofie Norgil Damgaard, Maarten Pieter Rozing, Volkert Siersma, Anne Møller, Katrine Tranberg
INTRODUCTION: People with severe mental illness (SMI) face a higher risk of premature mortality due to physical morbidity compared to the general population. Establishing regular contact with a general practitioner (GP) can mitigate this risk, yet barriers to healthcare access persist. Population initiatives to overcome these barriers require efficient identification of those persons in need. OBJECTIVE: To develop a predictive model to identify persons with SMI not attending a GP regularly...
April 23, 2024: BMC Psychiatry
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JOURNAL ARTICLE
Paula M C Mommersteeg, Paul Lodder, Wilbert Aarnoudse, Michael Magro, Jos W Widdershoven
BACKGROUND: We examined the risk of psychosocial distress, including Type D personality, depressive symptoms, anxiety, positive mood, hostility, and health status fatigue and disease specific and generic quality of life for MACE in patients with non-obstructive coronary artery disease (NOCAD). METHODS: In the Tweesteden mild stenosis (TWIST) study, 546 patients with NOCAD were followed for 10 years to examine the occurrence of cardiac mortality, a major cardiac event, or non-cardiac mortality in the absence of a cardiac event...
April 19, 2024: International Journal of Cardiology
#3
JOURNAL ARTICLE
Carla Bentes, Nuno Canas, Hugo Pedrosa, João Completo, Fábio Pereira, Magda Carrilho, José Lopes Lima, Cristina Pereira, Ricardo Rego, Helena Rocha, Francisca Sá, Francisco Sales, Manuela Santos, Rute Teotónio
INTRODUCTION: Epilepsy affects around 50 million people worldwide and is associated with lower quality of life scores, an increased risk of premature death, and significant socio-economic implications. The lack of updated evidence on current epidemiology and patient characterization creates considerable uncertainty regarding the epilepsy burden in Portugal. The study aims to characterize and quantify the epilepsy patients who have been hospitalized, with medical or surgical procedures involved, and to analyze their associated comorbidities and mortality rates...
April 19, 2024: Epilepsy & Behavior: E&B
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JOURNAL ARTICLE
Spyridon Roussos, Georgia Gerogianni, Georgios Vasilopoulos, Ioannis Koutelekos, Niki Pavlatou, Antonia Kalogianni, Georgia Toulia, Afroditi Zartaloudi, Maria Polikandrioti
INTRODUCTION: Epilepsy is a common neurological disease that is associated with increased morbidity and mortality globally. Persons with epilepsy (PWE) experience a heavy emotional burden mainly due to social stigmatization and limited opportunities in life. The purpose of this study was to explore factors associated with anxiety and depression in PWE. MATERIAL AND METHODS: In the present cross-sectional study, we enrolled 100 PWE who visited outpatient settings in a public hospital for scheduled follow-up...
March 2024: Curēus
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JOURNAL ARTICLE
Nicolas Salvetat, Francisco Jesus Checa-Robles, Aurélie Delacrétaz, Christopher Cayzac, Benjamin Dubuc, Diana Vetter, Jacques Dainat, Jean-Philippe Lang, Franziska Gamma, Dinah Weissmann
Bipolar disorder (BD) is a leading cause of disability worldwide, as it can lead to cognitive and functional impairment and premature mortality. The first episode of BD is usually a depressive episode and is often misdiagnosed as major depressive disorder (MDD). Growing evidence indicates that peripheral immune activation and inflammation are involved in the pathophysiology of BD and MDD. Recently, by developing a panel of RNA editing-based blood biomarkers able to discriminate MDD from depressive BD, we have provided clinicians a new tool to reduce the misdiagnosis delay observed in patients suffering from BD...
April 12, 2024: Journal of Affective Disorders
#6
JOURNAL ARTICLE
Yanjie Qi, Fanchao Meng, Xiuping Yan, Huanhuan Huang, Xu Chen, Fan He
BACKGROUND: The population with depression had a considerable excess mortality risk. This increased mortality may be attributed to the biological consequences of depression or the substantial prevalence of health risk behaviors (HRBs). This study aimed to quantify the combined effects of four major HRBs - smoking, excessive alcohol use, physical inactivity, and an unhealthy diet - on excess mortality among depressed individuals. METHODS: This study included 35,738 adults from the National Health and Nutrition Examination Survey 2005-06 to 2017-18, with mortality follow-up data censored through 2019...
April 10, 2024: Journal of Affective Disorders
#7
JOURNAL ARTICLE
Cohort profile: the PERSIAN Dena Cohort Study (PDCS) of non-communicable diseases in Southwest Iran.
Javad Harooni, Farahnaz Joukar, Reza Goujani, Masoumeh Khalighi Sikaroudi, Alireza Hatami, Mohammad-Amin Zolghadrpour, Mahdi Hejazi, Zahra Karimi, Fatemeh Rahmanpour, Sakineh Askari Shahid, Mohammad-Reza Jowshan
PURPOSE: This study conducted in Dena County is a population-based cohort study as part of the Prospective Epidemiological Research Studies in Iran (PERSIAN). The specific objectives of this study were to estimate the prevalence of region-specific modifiable risk factors and their associations with the incidence of major non-communicable diseases (NCDs). PARTICIPANTS: This PERSIAN Dena Cohort Study (PDCS) was conducted on 1561 men and 2069 women aged 35-70 years from October 2016 in Dena County, Kohgiluyeh and Boyer-Ahmad Province, Southwest Iran...
April 10, 2024: BMJ Open
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JOURNAL ARTICLE
Maureen E Groer, Kelley Baumgartel, Cary Springer, Tina Mutka, Teodor T Postolache
BACKGROUND: Maternal depression is considered a major contributor to morbidity and mortality in pregnancy. A population at risk are U.S. born or immigrant Hispanic women, and few prenatal depression or immune studies have focused on this population. OBJECTIVE: The research questions for the study were 1) What are the occurrences, risk factors and outcomes associated with depression in Hispanic pregnant women in the United States and 2) What are the associations of plasma immune cytokines and prenatal depression in this population...
July 2024: Brain, behavior, & immunity health
#9
JOURNAL ARTICLE
Yiu-Lam Yeung, Ka-Long Lee, Eric Sh Lau, Tsun-Fung Yung, Aimin Yang, Hongjiang Wu, Kelly Tc Wong, Alice Ps Kong, Elaine Yk Chow, Ronald Cw Ma, Theresa Yeung, Kit-Man Loo, Risa Ozaki, Andrea Oy Luk, Juliana Nm Lui, Juliana Cn Chan
BACKGROUND: Psychosocial status and patient reported outcomes (PRO) [depression and health-related quality-of-life (HRQoL)] are major health determinants. We investigated the association between depression and clinical outcomes in Chinese patients with type 2 diabetes (T2D), adjusted for PRO. METHODS: Using prospective data from Hong Kong Diabetes Register (2013-2019), we estimated the hazard-ratio (HR, 95%CI) of depression (validated Patient Health Questionnaire 9 (PHQ-9) score≥7) with incident cardiovascular disease (CVD), ischemic heart disease (IHD), chronic kidney disease (CKD: eGFR<60 ml/min/1...
2024: Frontiers in Endocrinology
#10
JOURNAL ARTICLE
Serena Chiara Civardi, Filippo Besana, Giovanni Carnevale Miacca, Filippo Mazzoni, Vincenzo Arienti, Pierluigi Politi, Natascia Brondino, Miriam Olivola
INTRODUCTION: Treatment-resistant depression (TRD) is commonly defined as the failure of at least two trials with antidepressant drugs, given at the right dose and for an appropriate duration. TRD is associated with increased mortality, compared to patients with a simple major depressive episode. This increased rate was mainly attributed to death from external causes, including suicide and accidents. The aim of our study is to identify socio-demographic and psychopathological variables associated with suicidal attempts in a sample of outpatients with TRD...
2024: Frontiers in Psychiatry
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JOURNAL ARTICLE
Ying Chen, Xiangxu Chen, Jialin Zhang, Xuejun Zhang, Dan Wang, Na Lu, Changsong Wang, Yingying Yue, Yonggui Yuan
ETHNOPHARMACOLOGICAL RELEVANCE: Major Depressive Disorder (MDD) emerges as a complex psychosomatic condition, notable for its considerable suicidality and mortality rates. Increasing evidence suggests the efficacy of Chinese herbal medicine in mitigating depression symptoms and offsetting the adverse effects associated with conventional Western therapeutics. Notably, clinical trials have revealed the adjunctive antidepressant potential of Kaiyu Zhishen Decoction (KZD) alongside Western medication...
April 4, 2024: Journal of Ethnopharmacology
#12
JOURNAL ARTICLE
John G Rizk, Jannat Saini, Kyungha Kim, Uzma Pathan, Danya M Qato
BACKGROUND: Opioid overdose deaths in the United States remain a major public health crisis. Little is known about counties with high rates of opioid overdose mortality but low availability of opioid use disorder (OUD) treatment facilities. We sought to identify characteristics of United States (US) counties with high rates of opioid overdose mortality and low rates of opioid treatment facilities. METHODS: Rates of overdose mortality from 3,130 US counties were compared with availability of opioid treatment facilities that prescribed or allowed medications for OUD (MOUD), from 2018-2019...
2024: PloS One
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JOURNAL ARTICLE
Dipen Patel, Yamiko Joseph Msosa, Tao Wang, Julie Williams, Omar G Mustafa, Siobhan Gee, Barbara Arroyo, Damian Larkin, Trevor Tiedt, Angus Roberts, Richard J B Dobson, Fiona Gaughran
BACKGROUND: Severe mental illnesses (SMIs), including schizophrenia, bipolar affective disorder, and major depressive disorder, are associated with an increased risk of physical health comorbidities and premature mortality from conditions including cardiovascular disease and diabetes. Digital technologies such as electronic clinical decision support systems (eCDSSs) could play a crucial role in improving the clinician-led management of conditions such as dysglycemia (deranged blood sugar levels) and associated conditions such as diabetes in people with a diagnosis of SMI in mental health settings...
April 5, 2024: JMIR Research Protocols
#14
JOURNAL ARTICLE
Chantal F Ski, Rod S Taylor, Karen McGuigan, Linda Long, Jeffrey D Lambert, Suzanne H Richards, David R Thompson
BACKGROUND: Depression and anxiety occur frequently (with reported prevalence rates of around 40%) in individuals with coronary heart disease (CHD), heart failure (HF) or atrial fibrillation (AF) and are associated with a poor prognosis, such as decreased health-related quality of life (HRQoL), and increased morbidity and mortality. Psychological interventions are developed and delivered by psychologists or specifically trained healthcare workers and commonly include cognitive behavioural therapies and mindfulness-based stress reduction...
April 5, 2024: Cochrane Database of Systematic Reviews
#15
JOURNAL ARTICLE
Ann Sophia Bertelsen, Tahir Masud, Charlotte Suetta, Lisbeth Rosenbek Minet, Stig Andersen, Jørgen T Lauridsen, Jesper Ryg
BACKGROUND: During hospitalisation, older patients spend most of their time passive in bed, which increases the risk of functional decline and negative adverse outcomes. Our aim is to examine the impact of robot-assisted physical training on functional status in older geriatric patients during acute hospitalisation. METHODS: This is a single-centre investigator-blinded placebo-controlled randomised controlled trial including geriatric patients aged ≥ 65 years, able to ambulate before hospitalisation, and with expected length of stay ≥ 2 days...
April 4, 2024: Trials
#16
JOURNAL ARTICLE
Casey Crump, Pär Stattin, James D Brooks, Jan Sundquist, Weiva Sieh, Kristina Sundquist
BACKGROUND: Men diagnosed with prostate cancer (PC) have an increased risk of depression; however, it is unclear to what extent depression affects long-term survival. A better understanding of such effects is needed to improve long-term care and outcomes for men with PC. OBJECTIVE: To determine the associations between major depression and mortality in a national cohort of men with PC. DESIGN, SETTING, AND PARTICIPANTS: A national cohort study was conducted of all 180 189 men diagnosed with PC in Sweden during 1998-2017...
April 3, 2024: European Urology Oncology
#17
REVIEW
F S Bahr, M Ricke-Hoch, E Ponimaskin, F E Müller
Acute myocardial infarction (AMI) is one of the leading causes of death worldwide and treatment costs pose a major burden on the global health care system. Despite the variety of treatment options, individual recovery can be still poor and the mortality rate, especially in the first few years after the event, remains high. Therefore, intense research is currently focused on identifying novel target molecules to improve the outcome following AMI. One of the potentially interesting targets is the serotonergic system (5-HT system), not at least because of its connection to mental disorders...
April 4, 2024: ACS Chemical Neuroscience
#18
JOURNAL ARTICLE
Chih-Ming Cheng, Mu-Hong Chen, Shih-Jen Tsai, Wen-Han Chang, Chia-Fen Tsai, Wei-Chen Lin, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Cheng-Ta Li
IMPORTANCE: Antidepressant responses and the phenotype of treatment-resistant depression (TRD) are believed to have a genetic basis. Genetic susceptibility between the TRD phenotype and other psychiatric disorders has also been established in previous genetic studies, but population-based cohort studies have not yet provided evidence to support these outcomes. OBJECTIVE: To estimate the TRD susceptibility and the susceptibility between TRD and other psychiatric disorders within families in a nationwide insurance cohort with extremely high coverage and comprehensive health care data...
April 3, 2024: JAMA Psychiatry
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JOURNAL ARTICLE
Arun K Bose, Jiri Doležal, Daniel Scherrer, Jan Altman, Daniel Ziche, Elisabet Martínez-Sancho, Christof Bigler, Andreas Bolte, Michele Colangelo, Isabel Dorado-Liñán, Igor Drobyshev, Sophia Etzold, Patrick Fonti, Arthur Gessler, Tomáš Kolář, Eva Koňasová, Kiril Aleksandrovich Korznikov, Francois Lebourgeois, Manuel Esteban Lucas-Borja, Annette Menzel, Burkhard Neuwirth, Manuel Nicolas, Alexander Mikhaylovich Omelko, Neil Pederson, Any Mary Petritan, Andreas Rigling, Michal Rybníček, Tobias Scharnweber, Jens Schröder, Fernando Silla, Irena Sochová, Kristina Sohar, Olga Nikolaevna Ukhvatkina, Anna Stepanovna Vozmishcheva, Roman Zweifel, J Julio Camarero
Forests are undergoing increasing risks of drought-induced tree mortality. Species replacement patterns following mortality may have a significant impact on the global carbon cycle. Among major hardwoods, deciduous oaks (Quercus spp.) are increasingly reported as replacing dying conifers across the Northern Hemisphere. Yet, our knowledge on the growth responses of these oaks to drought is incomplete, especially regarding post-drought legacy effects. The objectives of this study were to determine the occurrence, duration, and magnitude of legacy effects of extreme droughts and how that vary across species, sites, and drought characteristics...
March 27, 2024: Science of the Total Environment
#20
JOURNAL ARTICLE
Yosra Raddaoui, Ahmed Ben Amara, Aymen Noamen, Saoussen Antit, Youssef Hajri, Jamila Habli, Hassen Ibn Hadj Amor, Youssef Ben Youssef, Lilia Zakhama, Wafa Fehri
RESEARCH PROBLEM: Hypertension is a multifactorial disease that affects approximately one third of the Tunisian adult population. It is a major risk factor for stroke and cardiovascular disease. Environmental and psychosocial factors play an important role in hypertension onset and control. The prevalence of depression among hypertensive patients is 26, 8% and its presence is associated with increased risk of cardiovascular related morbi-mortality. Our study aims to evaluate the role of depression in blood pressure control among ambulatory hypertensive patients...
January 5, 2024: La Tunisie Médicale
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