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Major depression and mortality

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https://www.readbyqxmd.com/read/29135887/ischemia-reperfusion-injury-in-aged-livers-the-energy-metabolism-inflammatory-response-and-autophagy
#1
Chunyi Kan, Luisa Ungelenk, Amelie Lupp, Olaf Dirsch, Uta Dahmen
Due to the lack of adequate organs, the number of patients with end-stage liver diseases, acute liver failure or hepatic malignancies waiting for liver transplantation is constantly increasing. Accepting aged liver grafts is one of the strategies expanding the donor pool to ease the discrepancy between the growing demand and the limited supply of donor organs. However, recipients of organs from old donors may show an increased post-transplantation morbidity and mortality due to enhanced ischemia reperfusion injury...
November 11, 2017: Transplantation
https://www.readbyqxmd.com/read/29124951/the-role-of-serious-mental-illness-in-motivation-participation-and-adoption-of-health-behavior-change-among-obese-sedentary-latino-adults
#2
Daniel E Jimenez, Lauren Thomas, Stephen J Bartels
OBJECTIVE: Serious mental illness (SMI; e.g. schizophrenia, schizoaffective disorder, delusional disorder, bipolar disorder, severe major depressive disorder, and psychotic disorders) and Latino ethnicity can produce a compounded health disparity, placing individuals at particularly high risk for excess morbidity and premature mortality. In this study we sought to identify the role of SMI in motivation, participation, and adoption of health behavior change among overweight Latino adults...
November 10, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/29120929/risk-factors-for-opioid-induced-respiratory-depression-and-failure-to-rescue-a-review
#3
Kapil Gupta, Arun Prasad, Mahesh Nagappa, Jean Wong, Lusine Abrahamyan, Frances Chung
PURPOSE OF REVIEW: The primary objective of this review is to identify the risk factors for opioid-induced respiratory depression (OIRD) in the postoperative period. RECENT FINDINGS: In the postoperative period, OIRD has often been reported resulting in morbidity and mortality. The risk factors which predispose surgical patients to increased risk of OIRD are not clearly defined. A literature search was performed for adult surgical patients who were prescribed opioids during their hospital stay and any available reports on postoperative respiratory depression/respiratory events...
November 7, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/29101402/effect-of-sertraline-on-depressive-symptoms-in-patients-with-chronic-kidney-disease-without-dialysis-dependence-the-cast-randomized-clinical-trial
#4
S Susan Hedayati, L Parker Gregg, Thomas Carmody, Nishank Jain, Marisa Toups, A John Rush, Robert D Toto, Madhukar H Trivedi
Importance: Major depressive disorder (MDD) is prevalent among patients with chronic kidney disease (CKD) and is associated with morbidity and mortality. The efficacy and adverse events of selective serotonin reuptake inhibitors in these patients are unknown. Objective: To determine whether treatment with sertraline improves depressive symptoms in patients with CKD and MDD. Design, Setting, and Participants: The Chronic Kidney Disease Antidepressant Sertraline Trial (CAST) was a randomized, double-blind, placebo-controlled trial involving 201 patients with stage 3, 4, or 5 non-dialysis-dependent CKD, who were enrolled at 3 US medical centers...
November 3, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29092868/patients-outcomes-after-acute-respiratory-failure-a-qualitative-study-with-the-promis-framework
#5
Michelle N Eakin, Yashika Patel, Pedro Mendez-Tellez, Victor D Dinglas, Dale M Needham, Alison E Turnbull
BACKGROUND: As mortality rates for patients treated in intensive care units decrease, greater understanding of the impact of critical illness on patients' well-being is needed. OBJECTIVE: To describe the survivorship experience of patients who had acute respiratory failure by using the Patient Reported Outcomes Measurement Information System (PROMIS) framework. METHODS: A total of 48 adult patients who had acute respiratory failure completed at least 1 semistructured telephone-based interview between 5 and 18 months after their stay in the intensive care unit...
November 2017: American Journal of Critical Care: An Official Publication, American Association of Critical-Care Nurses
https://www.readbyqxmd.com/read/29070081/understanding-the-experience-of-initiating-community-based-physical-activity-and-social-support-by-people-with-serious-mental-illness-a-systematic-review-using-a-meta-ethnographic-approach
#6
Helen Quirk, Helen Crank, Deborah Harrop, Emma Hock, Robert Copeland
BACKGROUND: People with long-term serious mental illness live with severe and debilitating symptoms that can negatively influence their health and quality of life, leading to outcomes such as premature mortality, morbidity and obesity. An interplay of social, behavioural, biological and psychological factors is likely to contribute to their poor physical health. Participating in regular physical activity could bring symptomatic improvements, weight loss benefits, enhanced wellbeing and when undertaken in a community-based group setting can yield additional, important social support benefits...
October 25, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29066229/depression-and-cardiovascular-disease-in-elderly-current-understanding
#7
REVIEW
Yaxin Zhang, Yujing Chen, Lina Ma
Geriatric depression is a major public health problem and has an especially large effect on health when comorbid with a chronic medical condition. Hypertension, coronary heart disease, and diabetes are accompanied by a high incidence of depression and can affect the treatment and prognosis. Depression is a highly prevalent risk factor for incident of and is associated with morbidity and mortality of cardiovascular disease. In addition to the proactive and effective control of primary diseases, efforts should also be made to improve patients' psychological and social function...
October 21, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29053705/vagus-nerve-stimulation-in-pregnant-rats-and-effects-on-inflammatory-markers-in-the-brainstem-of-neonates
#8
Allison Judkins, Rhaya L Johnson, Samuel T Murray, Steven Yellon, Christopher G Wilson
BackgroundVagus Nerve Stimulation (VNS) is an FDA-approved method delivering electrical impulses for treatment of depression and epilepsy in adults. The vagus nerve innervates the majority of visceral organs and cervix, but potential impacts of VNS on the progress of pregnancy and the fetus are not well studied.MethodsWe tested the hypothesis that VNS in pregnant dams does not induce inflammatory changes in the cardiorespiratory control regions of the pups' brainstem, potentially impacting the morbidity and mortality of offspring...
October 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29045582/strategies-to-reduce-injuries-and-develop-confidence-in-elders-stride-a-cluster-randomized-pragmatic-trial-of-a-multifactorial-fall-injury-prevention-strategy-design-and-methods
#9
Shalender Bhasin, Thomas M Gill, David B Reuben, Nancy K Latham, Jerry H Gurwitz, Patricia Dykes, Siobhan McMahon, Thomas W Storer, Pamela W Duncan, David A Ganz, Shehzad Basaria, Michael E Miller, Thomas G Travison, Erich J Greene, James Dziura, Denise Esserman, Heather Allore, Martha B Carnie, Maureen Fagan, Catherine Hanson, Dorothy Baker, Susan L Greenspan, Neil Alexander, Fred Ko, Albert L Siu, Elena Volpi, Albert W Wu, Jeremy Rich, Stephen C Waring, Robert Wallace, Carri Casteel, Jay Magaziner, Peter Charpentier, Charles Lu, Katy Araujo, Haseena Rajeevan, Scott Margolis, Richard Eder, Joanne M McGloin, Eleni Skokos, Jocelyn Wiggins, Lawrence Garber, Steven B Clauser, Rosaly Correa-De-Araujo, Peter Peduzzi
Background: Fall injuries are a major cause of morbidity and mortality among older adults. We describe the design of a pragmatic trial to compare the effectiveness of an evidence-based, patient-centered multifactorial fall injury prevention strategy to an enhanced usual care. Methods: Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) is a 40-month cluster-randomized, parallel-group, superiority, pragmatic trial being conducted at 86 primary care practices in 10 healthcare systems across USA...
October 14, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29035088/the-last-25-years-of-obstructive-sleep-apnea-epidemiology-and-the-next-25
#10
Paul E Peppard, Erika W Hagen
Considerable new knowledge regarding the epidemiology of obstructive sleep apnea (OSA) in adults arose from large-scale population-based epidemiologic investigations that initiated in the late 1980s to 1990s; these investigations have continued to produce relevant findings in recent years. In this Perspective, we briefly comment on the past 25 years of adult population-based OSA epidemiology and discuss selected ways in which the field can further progress over the coming decades. Population-based studies have shown that OSA is common in both men and women, and that prevalence is increasing...
October 16, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29034135/heterogeneity-in-trajectories-of-depression-in-response-to-divorce-is-associated-with-differential-risk-for-mortality
#11
Matteo Malgaroli, Isaac R Galatzer-Levy, George A Bonanno
Divorce is a common stressful event associated with both increased rates of depression and mortality. Given evidence of significant individual differences in depression following major life stressors, we examined if heterogeneous depression responses confer differential risk for mortality. Data from a population based longitudinal study was utilized to identify individuals who experienced divorce (n=559). Prospective trajectories of depression severity from before to after divorce were identified using latent growth mixture modeling, and rates of mortality between trajectories were compared as a distal outcome...
September 2017: Clinical Psychological Science
https://www.readbyqxmd.com/read/29022358/development-of-the-injury-perceptions-questionnaire-injpq
#12
Irit Heruti, Sigal Levy, Ronit Avitsur, Daniel Deutscher, Moshe Gutvirtz, Tamar Berkovitz, Shoshana Shiloh
OBJECTIVES: Injuries are major causes of morbidity and mortality in the population. Given the central role of perceptions in self-regulation of health conditions, it is important to investigate how they are perceived. This article describes the development of the Injury Perceptions Questionnaire (InjPQ). METHODS: A concurrent study in a diverse sample of injured individuals (n = 333). The internal structure and the reliability (Cronbach's α) of InjPQ sub-scales were explored by factor analyses...
October 12, 2017: Psychology & Health
https://www.readbyqxmd.com/read/29022129/the-utility-of-local-anesthesia-for-neurosurgical-interventions-in-a-low-resource-setting-a-case-series
#13
Jessica Eaton, Asma Bilal Hanif, Suzgisam Mzumara, Anthony Charles
INTRODUCTION: Trauma is a major contributor to global morbidity and mortality, and injury to the central nervous system is the most common cause of death in these patients. While the provision of surgical services is being recognized as essential to global public health efforts, specialty areas such as neurosurgery remain overlooked. METHOD: This is a retrospective case review of patients with operable lesions, such as extra-axial hematomas and unstable depressed skull fractures that underwent neurosurgical interventions under local anesthesia...
October 11, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29021005/trends-in-depression-prevalence-in-the-usa-from-2005-to-2015-widening-disparities-in-vulnerable-groups
#14
A H Weinberger, M Gbedemah, A M Martinez, D Nash, S Galea, R D Goodwin
BACKGROUND: Major depression is associated with significant disability, morbidity, and mortality. The current study estimated trends in the prevalence of major depression in the US population from 2005 to 2015 overall and by demographic subgroups. METHODS: Data were drawn from the National Survey on Drug Use and Health (NSDUH), an annual cross-sectional study of US persons ages 12 and over (total analytic sample N = 607 520). Past-year depression prevalence was examined annually among respondents from 2005 to 2015...
October 12, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29018431/depression-of-vaccinal-immunity-to-marek-s-disease-by-infection-with-chicken-infectious-anemia-virus
#15
Yankun Zhang, Ning Cui, Ni Han, Jiayan Wu, Zhizhong Cui, Shuai Su
Marek's disease (MD) has been occurring with increasing frequency in chickens in recent years. To our knowledge, however, there has been no report of the very virulent plus (vv+) MD virus (MDV) field isolate in China. Studies have shown that dual infection with immunosuppressive viruses such as chicken infectious anemia virus (CIAV) occurs frequently in chickens developing MD. In this study, we performed a designed set of in vivo experiments, which comprised five different groups of chickens, including the group of CVI988/Rispens-vaccinated chickens, the groups of CVI988/Rispens-vaccinated chickens infected with MDV or CIAV or both viruses (MDV and CIAV), and the group of MDV-challenged chickens...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28992998/predictive-value-of-depression-and-anxiety-for-long-term-mortality-differences-in-outcome-between-acute-coronary-syndrome-and-stable-angina-pectoris
#16
Tom A J de Jager, Karolijn Dulfer, Sumant Radhoe, Michael J Bergmann, Joost Daemen, Ron T van Domburg, Mattie J Lenzen, Elisabeth M W J Utens
BACKGROUND: Since the early 2000s the treatment of choice for an acute myocardial infarction has moved from thrombolytic therapy to primary PCI (pPCI). As a result, the majority of patients undergoing PCI shifted from stable angina pectoris (SA) to acute coronary syndrome (ACS). Additionally the previously observed association between depression and anxiety and long-term outcome in patients who underwent a PCI may have been changed. The main objective of this study was to investigate the predictive value of depression and anxiety for 10-year mortality, in a cohort with post-PCI patients treated for SA versus patients treated for ACS...
October 6, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28983445/impact-of-cocaine-use-on-acute-ischemic-stroke-patients-insights-from-nationwide-inpatient-sample-in-the-united-states
#17
Rupak Desai, Upenkumar Patel, Chintan Rupareliya, Sandeep Singh, Manan Shah, Rikinkumar S Patel, Smit Patel, Zabeen Mahuwala
Cocaine is the third most common substance of abuse after cannabis and alcohol. The use of cocaine as an illicit substance is implicated as a causative factor for multisystem derangements ranging from an acute crisis to chronic complications. Vasospasm is the proposed mechanism behind adverse events resulting from cocaine abuse, acute ischemic strokes (AIS) being one of the few. Our study looked into in-hospital outcomes owing to cocaine use in the large population based study of AIS patients. Using the national inpatient sample (NIS) database from 2014 of United States of America, we identified AIS patients with cocaine use using International Classification of Disease, Ninth Revision (ICD-9) codes...
August 2, 2017: Curēus
https://www.readbyqxmd.com/read/28979128/medical-comorbidities-in-patients-with-serious-mental-illness-a-retrospective-study-of-mental-health-patients-attending-an-outpatient-clinic-in-qatar
#18
Monica Zolezzi, Sara Abdulrhim, Nour Isleem, Farah Zahrah, Yassin Eltorki
BACKGROUND: The life span of individuals with serious mental illness (SMI) is shorter compared to the general population. This excess mortality is mainly due to physical illness. The aim of the study was to investigate the prevalence rates of different physical illnesses in individuals with SMI and to examine how these are being managed. METHODS: The study was a cross-sectional retrospective chart review of a cohort of patients with SMI. A comprehensive electronic data extraction tool using SurveyMonkey(®) was used to collect patient demographics, psychiatric and medical comorbidities, medications and all relevant physical assessments...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28962608/benefits-of-home-based-multidisciplinary-exercise-and-supportive-care-in-inoperable-non-small-cell-lung-cancer-protocol-for-a-phase-ii-randomised-controlled-trial
#19
Lara Edbrooke, Sanchia Aranda, Catherine L Granger, Christine F McDonald, Mei Krishnasamy, Linda Mileshkin, Louis Irving, Sabine Braat, Ross A Clark, Ian Gordon, Linda Denehy
BACKGROUND: Lung cancer is one of the most commonly diagnosed cancers, and is a leading cause of cancer mortality world-wide. Due to lack of early specific symptoms, the majority of patients present with advanced, inoperable disease and five-year relative survival across all stages of non-small cell lung cancer (NSCLC) is 14%. People with lung cancer also report higher levels of symptom distress than those with other forms of cancer. Several benefits for survival and patient reported outcomes are reported from physical activity and exercise in other tumour groups...
September 29, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28960596/psychosocial-stress-and-major-cardiovascular-events-in-patients-with-stable-coronary-heart-disease
#20
E Hagström, F Norlund, A Stebbins, P W Armstrong, K Chiswell, C B Granger, J López-Sendón, D Pella, J Soffer, R Sy, L Wallentin, H D White, R A H Stewart, C Held
OBJECTIVES: Assess the risk of ischaemic events associated with psychosocial stress in patients with stable coronary heart disease (CHD). METHODS: Psychosocial stress was assessed by a questionnaire in 14 577 patients (median age 65.0, IQR 59, 71; 81.6% males) with stable CHD on optimal secondary preventive therapy in the prospective randomized STABILITY clinical trial. Adjusted Cox regression models were used to assess associations between individual stressors, baseline cardiovascular risk factors and outcomes...
September 28, 2017: Journal of Internal Medicine
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