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Major depression and mortality

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https://www.readbyqxmd.com/read/27915438/variations-in-clinical-presentation-and-anatomical-distribution-of-gross-lesions-of-african-swine-fever-in-domestic-pigs-in-the-southern-highlands-of-tanzania-a-field-experience
#1
Maulilio John Kipanyula, Solomon Wilson Nong'ona
African swine fever is a contagious viral disease responsible for up to 100% mortality among domestic pigs. A longitudinal study was carried out to determine the clinical presentation and anatomical distribution of gross lesions in affected pigs in Mbeya region, Tanzania during the 2010 to 2014 outbreaks. Data were collected during clinical and postmortem examination by field veterinarians and using a structured questionnaire. A total of 118 respondents (100%) showed awareness about African swine fever. During previous outbreaks, the mortality rate was almost 100%, while in 2014 it was estimated to be less than 50%...
December 3, 2016: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/27894012/depression-in-cancer-the-many-biobehavioral-pathways-driving-tumor-progression
#2
REVIEW
Beatrice Bortolato, Thomas N Hyphantis, Sara Valpione, Giulia Perini, Michael Maes, Gerwyn Morris, Marta Kubera, Cristiano A Köhler, Brisa S Fernandes, Brendon Stubbs, Nicholas Pavlidis, André F Carvalho
Major Depressive Disorder (MDD) is common among cancer patients, with prevalence rates up to four-times higher than the general population. Depression confers worse outcomes, including non-adherence to treatment and increased mortality in the oncology setting. Advances in the understanding of neurobiological underpinnings of depression have revealed shared biobehavioral mechanisms may contribute to cancer progression. Moreover, psychosocial stressors in cancer promote: (1) inflammation and oxidative/nitrosative stress; (2) a decreased immunosurveillance; and (3) a dysfunctional activation of the autonomic nervous system and of the hypothalamic-pituitaryadrenal axis...
November 16, 2016: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/27892699/genetics-of-consanguinity-and-inbreeding-in-health-and-disease
#3
Mohd Fareed, Mohammad Afzal
CONTEXT: Inbreeding increases the level of homozygotes for autosomal recessive disorders and is the major objective in clinical studies. The prevalence of consanguinity and the degree of inbreeding vary from one population to another depending on ethnicity, religion, culture and geography. Global epidemiological studies have revealed that consanguineous unions have been significantly associated with increased susceptibility to various forms of inherited diseases Objective: The study aimed to determine the role of consanguinity in human health and to highlight the associated risks for various diseases or disorders...
November 28, 2016: Annals of Human Biology
https://www.readbyqxmd.com/read/27879500/implications-of-preterm-birth-for-maternal-mental-health-and-infant-development
#4
Cheryl Anderson, Priscila Cacola
Preterm birth remains a major contributor to infant mortality and morbidity including neurodevelopmental delay and childhood disability. Mothers experiencing a preterm birth are at risk for maternal mental health issues, inclusive of depression and posttraumatic stress disorder (PTSD), which may affect mother-infant attachment and infant development. Depression and PTSD, frequently comorbid, following preterm birth and relationships between these symptoms, maternal-infant attachment, and infant development are reviewed...
November 22, 2016: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/27872937/major-depression-in-primary-care-making-the-diagnosis
#5
Chung Wai Mark Ng, Choon How How, Yin Ping Ng
Major depression is a common condition seen in the primary care setting, often presenting with somatic symptoms. It is potentially a chronic illness with considerable morbidity, and a high rate of relapse and recurrence. Major depression has a bidirectional relationship with chronic diseases, and a strong association with increased age and coexisting mental illnesses (e.g. anxiety disorders). Screening can be performed using clinical tools for major depression, such as the Patient Health Questionaire-2, Patient Health Questionaire-9 and Beck Depression Inventory, so that timely treatment can be initiated...
November 2016: Singapore Medical Journal
https://www.readbyqxmd.com/read/27866392/drug-caused-deaths-in-australian-medical-practitioners-and-health-care-professionals
#6
Jennifer L Pilgrim, Rhyse Dorward, Olaf H Drummer
BACKGROUND AND AIMS: There are numerous factors putting health-care professionals (HCP) at a higher risk of substance abuse and premature death, including high-stress jobs, access to controlled substances, long hours of practice and constant contact with the critically ill. This study aimed to examine fatal drug toxicity in this high-risk cohort, in order to: (1) estimate the rate of drug-caused deaths of Australian HCPs; (2) describe the key characteristics of the cohort; and (3) examine the relationship between HCP occupation and drug type, or intent...
November 20, 2016: Addiction
https://www.readbyqxmd.com/read/27860117/development-of-a-core-outcome-set-for-epilepsy-in-pregnancy-e-core-a-national-multi-stakeholder-modified-delphi-consensus-study
#7
B H Al Wattar, K Tamilselvan, R Khan, A Kelso, A Sinha, A M Pirie, D McCorry, K S Khan, S Thangaratinam
OBJECTIVE: To develop a set of core outcomes for studies on pregnant women with epilepsy. DESIGN: Delphi consensus study. POPULATION: Healthcare professionals, and patient representatives with lived experience of epilepsy in the UK. METHODS: We used a modified Delphi method and a consultation meeting to achieve consensus. Potential outcomes were identified by systematic review, and were scored using a Likert scale anchored between 1 (least important) and 5 (most important)...
November 16, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27856684/psychedelics-in-the-treatment-of-unipolar-mood-disorders-a-systematic-review
#8
REVIEW
James Jh Rucker, Luke A Jelen, Sarah Flynn, Kyle D Frowde, Allan H Young
Unipolar mood disorders, including major depressive disorder and persistent depressive disorder (dysthymia), confer high rates of disability and mortality and a very high socioeconomic burden. Current treatment is suboptimal in most cases and there is little of note in the pharmaceutical development pipeline. The psychedelic drugs, including lysergic acid diethylamide and psilocybin, were used extensively in the treatment of mood disorders, and other psychiatric conditions, before their prohibition in the late 1960s...
December 2016: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/27832209/handgrip-strength-and-factors-associated-in-poor-elderly-assisted-at-a-primary-care-unit-in-rio-de-janeiro-brazil
#9
Valéria Teresa Saraiva Lino, Nádia Cristina Pinheiro Rodrigues, Gisele O'Dwyer, Mônica Kramer de Noronha Andrade, Inês Echenique Mattos, Margareth Crisóstomo Portela
INTRODUCTION: Sarcopenia is a condition diagnosed when the patient presents low muscle mass, plus low muscle strength or low physical performance. Muscle weakness in the oldest (dynapenia) is a major public health concern because it predicts future all-cause mortality and is associated with falls, disability, cardiovascular mortality and morbidity. Grip strength is a simple method for assessment of muscle function in clinical practice. OBJECTIVE: To estimate the grip strength and identify factors associated with handgrip strength variation in elderly people with low socioeconomic status...
2016: PloS One
https://www.readbyqxmd.com/read/27830572/inflammation-associated-co-morbidity-between-depression-and-cardiovascular-disease
#10
Angelos Halaris
Morbidity and mortality of cardiovascular disease (CVD) is exceedingly high worldwide. Depressive illness is a serious psychiatric illness that afflicts a significant portion of the world population. Epidemiological studies have confirmed the high co-morbidity between these two disease entities. The co-morbidity is bidirectional and the mechanisms responsible for it are complex and multifaceted. In addition to genetic, biological systems, psychosocial, and behavioral factors that are involved include the central and autonomic nervous systems, the neuroendocrine, immune, and the vascular and hematologic systems...
November 10, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/27822693/sulfur-dioxide-inhibits-expression-of-mitochondrial-oxidative-phosphorylation-genes-encoded-by-both-nuclear-dna-and-mitochondrial-dna-in-rat-lungs
#11
Guohua Qin, Jiaoxia Wang, Nan Sang
Epidemiological studies show that sulfur dioxide (SO2), a major air pollutant, is associated with the morbidity and mortality of respiratory tract diseases. The aim of the present study was to determine the effects of SO2 on mitochondria and the corresponding molecular characterization in the lung. Male Wistar rats were exposed to 0, 3.5, 7, and 14 mg/m(3) SO2 (4 h/day, 30 days). Mitochondrial dysfunction including decreases of cytochrome c oxidase (COX) activity and mitochondrial membrane potential (MMP) was observed in the lungs of rats after SO2 inhalation...
November 8, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27822399/diagnosis-of-dilated-cardiomyopathy-patient-reaction-and-adaptation-case-study-and-review-of-the-literature
#12
Solomis Solomou, Maria Stavrou, Justin Marley
Objective. Heart failure remains a major cause of morbidity and mortality. Given that heart failure generally has a chronic course, it is important to appreciate the impact it can have on the quality of life of patients and also their partners or family carers. Method. Questionnaires were given to a patient newly diagnosed with dilated cardiomyopathy, during his hospital admission, as well as after discharge. The responses are summarised and explored in the discussion section, where we used review of the literature to discuss the implications of a new diagnosis of heart failure...
2016: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/27810717/the-effectiveness-of-group-based-behavioral-activation-in-the-treatment-of-depression-an-updated-meta-analysis-of-randomized-controlled-trial
#13
Aaroy T Y Chan, Grace Y Y Sun, Wilson W S Tam, Kelvin K F Tsoi, Samuel Y S Wong
BACKGROUND: Depression is a common mental health problem associated with significant morbidity and mortality. Amongst various psychological treatments for depression, individual behavioral activation (BA) has been shown to be effective and relatively simple in its delivery by health care providers although its effectiveness as a group based intervention requires further evidence. The objective of this study is to evaluate and update on the effectiveness of group-based BA to relieve symptoms of depression...
October 15, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27810668/risk-factors-for-suicide-attempt-in-pregnancy-and-the-post-partum-period-in-women-with-serious-mental-illnesses
#14
Florence Gressier, Virginie Guillard, Odile Cazas, Bruno Falissard, Nine M-C Glangeaud-Freudenthal, Anne-Laure Sutter-Dallay
Suicide is a major public health concern worldwide, and mental disorders have been identified as a main risk factor. Suicide is also one of the leading causes of perinatal maternal mortality, but very few studies have focused on suicide attempts (SA) in the perinatal period. This work aims to assess risk factors associated with SA in pregnancy and in the post-partum period in women with mental health disorders. Women (n = 1439) with psychiatric disorders jointly admitted with their infant to 16 psychiatric Mother-Baby Units over 10 years (2001-2010) were assessed retrospectively for the occurrence of SA in pregnancy or the postpartum period...
October 13, 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27793216/toxoplasma-gondii-a-gastrointestinal-pathogen-associated-with-human-brain-diseases
#15
E G Severance, J Xiao, L Jones-Brando, S Sabunciyan, Y Li, M Pletnikov, E Prandovszky, R Yolken
Serious psychiatric disorders such as schizophrenia, bipolar disorder, and major depression are important causes of mortality and morbidity worldwide. While these are primarily diseases involving altered brain functioning, numerous studies have documented increased rates of gastrointestinal inflammation and dysfunction in many individuals with these disorders. Toxoplasma gondii is an apicomplexan protozoan intracellular parasite with a widespread distribution in both developed and developing countries. Toxoplasma organisms enter the ecosystem through the shedding of oocysts by Toxoplasma-infected felines...
2016: International Review of Neurobiology
https://www.readbyqxmd.com/read/27782359/iceberg-killing-fields-limit-huge-potential-for-benthic-blue-carbon-in-antarctic-shallows
#16
David K A Barnes
Climate-forced ice losses are increasing potential for iceberg-seabed collisions, termed ice scour. At Ryder Bay, West Antarctic Peninsula (WAP) sea ice, oceanography, phytoplankton and encrusting zoobenthos have been monitored since 1998. In 2003, grids of seabed markers, covering 225 m(2) , were established, surveyed and replaced annually to measure ice scour frequency. Disturbance history has been recorded for each m(2) of seabed monitored at 5-25 m for ~13 years. Encrusting fauna, collected from impacted and nonimpacted metres each year, show coincident benthos responses in growth, mortality and mass of benthic immobilized carbon...
October 26, 2016: Global Change Biology
https://www.readbyqxmd.com/read/27768557/describing-the-population-health-burden-of-depression-health-adjusted-life-expectancy-by-depression-status-in-canada
#17
C Steensma, L Loukine, H Orpana, L McRae, J Vachon, F Mo, M Boileau-Falardeau, C Reid, B C Choi
INTRODUCTION: Few studies have evaluated the impact of depression in terms of losses to both premature mortality and health-related quality of life (HRQOL) on the overall population. Health-adjusted life expectancy (HALE) is a summary measure of population health that combines both morbidity and mortality into a single summary statistic that describes the current health status of a population. METHODS: We estimated HALE for the Canadian adult population according to depression status...
October 2016: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/27766299/role-of-omega-3-fatty-acids-in-the-etiology-treatment-and-prevention-of-depression-current-status-and-future-directions
#18
Robert K McNamara
Over the past three decades a body of translational evidence has implicated dietary deficiency in long-chain omega-3 (LCn-3) fatty acids, including eicosapenaenoic acid (EPA) and docosahexaenoic acid (DHA), in the pathophysiology and etiology of major depressive disorder (MDD). Cross-national and cross-sectional data suggest that greater habitual intake of preformed EPA+DHA is associated with reduced risk for developing depressive symptoms and syndromal MDD. Erythrocyte EPA and DHA composition is highly correlated with habitual fish or fish oil intake, and case-control studies have consistently observed lower erythrocyte EPA and/or DHA levels in patients with MDD...
September 2016: Journal of Nutrition & Intermediary Metabolism
https://www.readbyqxmd.com/read/27753839/sy-06-3-role-of-surgical-treatment-of-morbid-obesity
#19
Wei-Jei Lee
Obesity is a pan-endemic health problem in both developed and developing countries, in both western and eastern countries. It increases risk for many common diseases, including type 2 diabetes, dyslipidemia, hypertension, obstructive sleep apnea, heart disease, stroke, asthma, osteoarthritis, cancers and depression etc.. Although the incidence of obesity in Asia is relatively low, Asian patients tend to have similar incidence of obesity related metabolic syndrome at lower BMI level comparing to Caucasians because of central obesity...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753832/sy-04-2-long-term-cvd-risk-prediction-in-low-incidence-european-populations
#20
Giovanni Veronesi
In Italy, the European SCORE Project risk score is the recommended tool for cardiovascular disease risk stratification in the primary prevention setting. Among non-diabetic subjects aged 40 to 64, the model estimates the 10-year probability of death due to cardiovascular disease based on individual's age, total cholesterol, blood pressure and smoking status. A growing body of evidence suggests that in middle-aged adults this stratification may suffer from two major drawbacks. First, mortality risk severely underestimates the global burden of disease incidence...
September 2016: Journal of Hypertension
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