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Head and neck, thyroid, melanoma, skin cancer

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https://www.readbyqxmd.com/read/26951748/italian-cancer-figures-report-2015-the-burden-of-rare-cancers-in-italy
#1
Susanna Busco, Carlotta Buzzoni, Sandra Mallone, Annalisa Trama, Marine Castaing, Francesca Bella, Rosalba Amodio, Sabrina Bizzoco, Tiziana Cassetti, Claudia Cirilli, Rosanna Cusimano, Roberta De Angelis, Mario Fusco, Gemma Gatta, Valerio Gennaro, Adriano Giacomin, Paolo Giorgi Rossi, Lucia Mangone, Salvatore Mannino, Silvia Rossi, Daniela Pierannunzio, Andrea Tavilla, Sandro Tognazzo, Rosario Tumino, Massimo Vicentini, Maria Francesca Vitale, Emanuele Crocetti, Luigino DalMaso
OBJECTIVES This collaborative study, based on data collected by the network of Italian Cancer Registries (AIRTUM), describes the burden of rare cancers in Italy. Estimated number of new rare cancer cases yearly diagnosed (incidence), proportion of patients alive after diagnosis (survival), and estimated number of people still alive after a new cancer diagnosis (prevalence) are provided for about 200 different cancer entities. MATERIALS AND METHODS Data herein presented were provided by AIRTUM population- based cancer registries (CRs), covering nowadays 52%of the Italian population...
January 2016: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/26601999/electrochemotherapy-as-palliative-treatment-in-patients-with-thyroid-papillary-carcinoma
#2
Juan José Grau, Miguel Caballero, Cristobal Langdon, Manuel Bernal-Sprekelsen, Jose Luis Blanch
INTRODUCTION: Local progression of papillary thyroid carcinoma (PTC) after failure of standard therapies may cause pain, ulceration, and bleeding. As patients are fully aware of the tumor growth, they might suffer high grade anxiety. Electrochemotherapy (ECT) is a new local palliative treatment for skin metastases of malignant melanoma or other tumors, including squamous head e neck cancer patients. OBJECTIVE: To evaluate the impact of ECT in patients with local progression of PTC...
May 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/26584878/other-primary-systemic-cancers-in-patients-with-melanoma-analysis-of-balanced-acral-and-nonacral-melanomas
#3
Soo Hyeon Bae, Hyun Ju Seon, Yoo Duk Choi, Hyun-Jeong Shim, Jee-Bum Lee, Sook Jung Yun
BACKGROUND: Although other primary systemic cancers in patients with melanoma have been studied, there have been few focusing on acral melanomas. OBJECTIVES: We assessed other primary systemic cancers in patients with acral and nonacral melanomas. METHODS: We analyzed other primary cancers in 452 patients with melanoma from 1994 to 2013. Metachronous cancers were defined as those given a diagnosis more than 2 months after diagnosis of melanoma...
February 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/25690858/profile-of-head-and-neck-cancers-in-dr-l%C3%A3-tfi-k%C3%A4-rdar-kartal-educational-and-research-hospital
#4
Kayhan Başak, Yasin Sağlam, Ayşe Gökçen Yildiz, Merve Başar, Hanım İstem Köse, Şükran Kayipmaz, Nimet Karadayi
OBJECTIVE: Head and neck cancers account for 17.6% of all malignant neoplasms. Data on the incidence of head and neck cancers and histological subtypes in Turkey are limited. This study aimed to provide an overview of statistics for head and neck cancers. MATERIAL AND METHOD: This retrospective and descriptive study included 1973 cases of in-situ carcinomas, malignant and borderline neoplasia from the head and neck region in a period of 5 years, diagnosed at Dr...
2015: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/25207361/vitamin-d-receptor-polymorphisms-and-cancer
#5
REVIEW
Sara Gandini, Patrizia Gnagnarella, Davide Serrano, Elena Pasquali, Sara Raimondi
It was suggested that vitamin D levels influence cancer development. The vitamin D receptor (VDR) is a crucial mediator for the cellular effects of vitamin D. In fact It has been hypothesized that polymorphisms in the VDR gene affect cancer risk and the relevance of VDR gene restriction fragment length polymorphisms for various types of cancer has been investigated by a great number of studies. However, results from previous studies on the association of VDR polymorphisms with different cancer types are somewhat contradictory, and the role of VDR in the etiology of cancer is still equivocal...
2014: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/23436251/birth-rates-among-female-cancer-survivors-a-population-based-cohort-study-in-sweden
#6
COMPARATIVE STUDY
Mikael Hartman, Jenny Liu, Kamila Czene, Hui Miao, Kee Seng Chia, Agus Salim, Helena M Verkooijen
BACKGROUND: More women of fertile age are long-term survivors of cancer. However, population-based data on birth rates of female cancer survivors are rare. METHODS: A total of 42,691 women ≤ 45 years with a history of cancer were identified from the Swedish Multi-Generation Register and the Swedish Cancer Register, for whom relative birth rates were calculated as compared to the background population, ie, standardized birth ratios (SBRs). Independent factors associated with reduced birth rates among cancer survivors were estimated using Poisson modeling...
May 15, 2013: Cancer
https://www.readbyqxmd.com/read/23300677/do-female-cancer-patients-display-better-survival-rates-compared-with-males-analysis-of-the-korean-national-registry-data-2005-2009
#7
COMPARATIVE STUDY
Kyu-Won Jung, Sohee Park, Aesun Shin, Chang-Mo Oh, Hyun-Joo Kong, Jae Kwan Jun, Young-Joo Won
BACKGROUND: Sex differences have been reported in the prognosis of certain cancers. In this study, we investigated whether Korean females display better survival rates compared with male patients for solid tumor sites. METHODS: We analyzed data from the Korean National Cancer Incidence Database from 599,288 adult patients diagnosed with solid cancers between 2005 and 2009. Patients were followed until December 2010. We applied a relative excess risk (RER) model adjusting for year of follow-up, age at diagnosis, and stage at diagnosis...
2012: PloS One
https://www.readbyqxmd.com/read/19304027/metastatic-tumors-to-the-oral-and-maxillofacial-region-a-retrospective-study-of-19-cases-in-west-china-and-review-of-the-chinese-and-english-literature
#8
REVIEW
Mo-Lun Shen, Jian Kang, Yan-Li Wen, Wei-Min Ying, Jie Yi, Cheng-Ge Hua, Xiu-Fa Tang, Yu-Ming Wen
PURPOSE: The aim of this article was to obtain an overview of metastatic tumors to the oral and maxillofacial (OMF) region, especially the differences in the constituent ratios of primary cancers between the United States and China. PATIENTS AND METHODS: Clinical findings of 19 cases encountered in West China Hospital of Stomatology were summarized and the English and Chinese literature were reviewed and analyzed. The main clinical features of OMF metastases were summarized, with an emphasis on primary cancers' constituents...
April 2009: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/19109009/the-advantage-of-women-in-cancer-survival-an-analysis-of-eurocare-4-data
#9
MULTICENTER STUDY
A Micheli, R Ciampichini, W Oberaigner, L Ciccolallo, E de Vries, I Izarzugaza, P Zambon, G Gatta, R De Angelis
We analysed 1.6 million population-based EUROCARE-4 cancer cases (26 cancer sites, excluding sex-specific sites, and breast) from 23 countries to investigate the role of sex in cancer survival according to age at diagnosis, site, and European region. For 15 sites (salivary glands, head and neck, oesophagus, stomach, colon and rectum, pancreas, lung, pleura, bone, melanoma of skin, kidney, brain, thyroid, Hodgkin disease and non-Hodgkin's lymphoma) age- and region-adjusted relative survival was significantly higher in women than men...
April 2009: European Journal of Cancer
https://www.readbyqxmd.com/read/17875856/multicentric-prospective-study-on-the-prevalence-of-sublevel-iib-metastases-in-head-and-neck-cancer
#10
MULTICENTER STUDY
Andrea Bolzoni Villaret, Cesare Piazza, Giorgio Peretti, Luca Calabrese, Mohssen Ansarin, Fausto Chiesa, Raul Pellini, Giuseppe Spriano, Piero Nicolai
OBJECTIVE: To evaluate the prevalence of sublevel IIB lymph node (LN) metastases for head and neck primary tumors in a large cohort of patients. DESIGN: Prospective study. SETTING: One referral university hospital and 2 national institutes of oncology. PATIENTS: Between 2003 and 2005, 297 patients (male to female ratio, 3.5:1; mean age, 58.8 years [range, 18-89 years]) affected by head and neck cancer were treated by surgery on the primary tumor and/or the neck...
September 2007: Archives of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/17825660/the-role-of-sentinel-node-biopsy-in-patients-with-cutaneous-melanoma
#11
REVIEW
Lakshi M Aldredge
The role of sentinel lymph node biopsy (SLNB) as a prognostic indicator in melanoma patients has been controversial in the fields of surgical oncology and dermatology for decades. This minimally invasive surgical technique was introduced in 1990 for diagnosing melanoma lymphatic metastases and has been deemed the standard of surgical care of cutaneous malignant melanoma by the World Health Organization and the Sunbelt Melanoma Clinical Trial. Its usefulness as a prognostic indicator of metastases led to expanded applications for breast, colon, gastric, esophageal, head and neck, thyroid, and lung cancers...
September 2007: Nursing Clinics of North America
https://www.readbyqxmd.com/read/17005598/lymphatic-mapping-and-sentinel-node-analysis-current-concepts-and-applications
#12
REVIEW
Steven L Chen, Douglas M Iddings, Randall P Scheri, Anton J Bilchik
Since the introduction of sentinel node biopsy in 1990 as a minimally invasive surgical technique for the diagnosis of melanoma lymphatic metastases, the number of applications has expanded. We review applications and the current status of sentinel node biopsy in melanoma, breast, colon, gastric, esophageal, head and neck, thyroid, and lung cancer. Variations on techniques specific to each organ are explained, and the current role of sentinel node biopsy in diagnosis and treatment is discussed.
September 2006: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/16857415/tumours-of-familial-origin-in-the-head-and-neck
#13
REVIEW
Carlos Suárez, Juan Pablo Rodrigo, Alfio Ferlito, Rubén Cabanillas, Ashok R Shaha, Alessandra Rinaldo
Individuals with inherited cancer syndromes are at significant risk of developing both benign and malignant tumours as a result of a germline mutation in a specific tumour suppressor gene. Tumours of familial origin are a rare event in the head and neck but despite this, they deserve a growing interest. Familial paragangliomas are most of the time limited to the paraganglionar system, but also may be part of different syndromic associations. Since early detection of paragangliomas reduces the incidence of morbidity and mortality, genotypic analysis in the search of SDHB, SDHC and SDHD mutations in families of affected patients plays a front-line diagnostic role, leading to more efficient patient management...
November 2006: Oral Oncology
https://www.readbyqxmd.com/read/15872346/detection-of-unexpected-additional-primary-malignancies-with-pet-ct
#14
Takayoshi Ishimori, Pavni V Patel, Richard L Wahl
UNLABELLED: This study evaluated the yield of whole-body (18)F-FDG PET/CT for the detection of unexpected (18)F-FDG-avid additional primary malignant tumors in patients being evaluated by PET/CT for known or suspected malignances. METHODS: Reports from whole-body (18)F-FDG PET/CT scans from June 2001 to June 2003 were reviewed, and 1,912 patients (924 men and 988 women; mean age +/- SD, 58.9 +/- 13.9 y) who had been scanned for known or suspected malignant lesions were included in this study...
May 2005: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/15190496/lymphatic-mapping-for-staging-of-head-and-neck-cancer
#15
REVIEW
Jai Balkissoon, Barry M Rasgon, Laurie Schweitzer
Lymphatic mapping with sentinel lymph node (SLN) biopsy can accurately stage the nodal basins in patients with melanoma of the trunk and extremities and has become a routine, well-accepted diagnostic method for melanoma at these anatomic locations. Melanoma of the head and neck (16% of all cases of melanoma) is complex and difficult to manage because of the rich abundant interlacing lymphatic drainage patterns, as well as watershed areas, which can lead to unusual and unexpected drainage patterns. Radioguided surgery in combination with blue dye facilitates localization of the SLN in the head and neck; however, this type of radioguided surgery is an evolving technique of some difficulty and thus requires careful coordination among the surgeon, nuclear medicine physician, and pathologist...
June 2004: Seminars in Oncology
https://www.readbyqxmd.com/read/15168727/cathepsin-d-expression-levels-in-nongynecological-solid-tumors-clinical-and-therapeutic-implications
#16
REVIEW
Gaetano Leto, Francesca M Tumminello, Marilena Crescimanno, Carla Flandina, Nicola Gebbia
Cathepsin D is a lysosomal acid proteinase which is involved in the malignant progression of breast cancer and other gynecological tumors. Clinical investigations have shown that in breast cancer patients cathepsin D overexpression was significantly correlated with a shorter free-time disease and overall survival, whereas in patients with ovarian or endometrial cancer this phenomenon was associated with tumor aggressiveness and a degree of chemoresistance to various antitumor drugs such as anthracyclines, cis-platinum and vinca alkaloids...
2004: Clinical & Experimental Metastasis
https://www.readbyqxmd.com/read/14991890/new-fields-of-application-of-the-sentinel-lymph-node-biopsy-in-the-pathologic-staging-of-solid-neoplasms-review-of-literature-and-surgical-perspectives
#17
REVIEW
Marco Gipponi, Nicola Solari, Franco C Di Somma, Sergio Bertoglio, Ferdinando Cafiero
Sentinel lymph node (sN) biopsy has gained special attention among surgical and medical oncologists as it represents an accepted technique for detecting occult nodal disease in regional lymph nodes of patients with melanoma and breast cancer. The histopathologic examination of the sN may well predict regional lymph node status in order to define the most suitable loco-regional and systemic treatment. Recently, this technique has also been applied to other solid tumor types such as gynecologic and urologic malignancies, squamous head and neck cancer, thyroid cancer, non-small-cell lung cancer, Merkel cell carcinoma, and gastric cancer...
March 2004: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/14684501/eurocare-3-survival-of-cancer-patients-diagnosed-1990-94-results-and-commentary
#18
M Sant, T Aareleid, F Berrino, M Bielska Lasota, P M Carli, J Faivre, P Grosclaude, G Hédelin, T Matsuda, H Møller, T Möller, A Verdecchia, R Capocaccia, G Gatta, A Micheli, M Santaquilani, P Roazzi, D Lisi et al.
EUROCARE-3 analysed the survival of 1815584 adult cancer patients diagnosed from 1990 to 1994 in 22 European countries. The results are reported in tables, one per cancer site, coded according to the International Classification of Diseases (ICD)-9 classification. The main findings of the tables are summarised and commented on in this article. For most solid cancers, wide differences in survival between different European populations were found, as also reported by EUROCARE-1 and EUROCARE-2, despite a remarkable (10%) overall increase in cancer survival from 1985 to 1994...
2003: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/12088110/nonmelanoma-skin-cancers-and-risk-of-subsequent-malignancies-a-cancer-registry-based-study-in-bulgaria
#19
COMPARATIVE STUDY
P Troyanova, S Danon, T Ivanova
Analysis of new primary tumors following nonmelanoma skin cancers (NMSC) has a public health and risk assessment interest, as well as potential implications for etiologic inference. The aim of this study is to evaluate the risk of the second primary tumors occurrence after NMSC development. A cohort of 2620 cases (1335 males and 1285 females) with nonmelanoma skin cancers registered in Bulgarian National Cancer Registry in 1993 was examined. The follow-up period represented a total of 15,856 person-years at risk...
2002: Neoplasma
https://www.readbyqxmd.com/read/11667993/upper-jugular-lymph-nodes-submuscular-recess-in-non-squamous-cell-cancer-of-the-head-and-neck-surgical-considerations
#20
Y P Talmi, Z Horowitz, M Wolf, L Bedrin, M Peleg, R Yahalom, J Kronenberg
Cervical lymphadenectomy of level II encompasses lymph nodes associated with the upper internal jugular vein and the spinal accessory nerve (SAN). Removal of tissue superior to the SAN (submuscular recess-(SMR)) was recently shown to be unwarranted in selected cases of squamous-cell cancer. Thirty-five patients with non-squamous-cell cancer (SCC) of the head and neck treated with cervical lymphadenectomy were prospectively evaluated. Thirty-seven neck dissection specimens were histologically analysed for the number of lymph nodes involved with cancer...
October 2001: Journal of Laryngology and Otology
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