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Gürsel Soybir, Cemalettin Topuzlu, Ozgür Odabaş, Kemal Dolay, Ayhan Bilir, Ferda Köksoy
PURPOSE: The pineal gland hormone melatonin is a well-known neoroendocrine hormone. In addition to its immunomodulator effect, it also has a positive effect on monocyte, cytokine, and fibroblast proliferations, which also influence angiogenesis. This study investigated the effects of melatonin hormone on angiogenesis in wound healing on 100 Wistar-Albino rats. METHODS: The rats were divided into two groups. Melatonin dissolved in 0.9% NaCl was administered to the study group in a dose of 0...
2003: Surgery Today
A Parducz, A Zsarnovszky, F Naftolin, T L Horvath
It has been shown that gonadal steroids have the capacity to induce synaptic plasticity in certain areas of the nervous system. Previously we have demonstrated that due to the effect of estradiol there is a transient decrease in the number of GABAergic axo-somatic synapses in the arcuate nucleus. By using systemic application of the tracer Fluorogold we retrogradely labeled a subpopulation of arcuate neurons that project to the median eminence. We than applied the disector method for synapse quantification and found that these "hypophysiotropic neurons" receive less axo-somatic inputs...
2003: Neuroscience
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