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https://www.readbyqxmd.com/read/28643887/personality-dopamine-and-parkinson-s-disease-insights-from-subthalamic-stimulation
#1
Eugénie Lhommée, François Boyer, Maxime Wack, Pierre Pélissier, Hélène Klinger, Emmanuelle Schmitt, Amélie Bichon, Valérie Fraix, Stéphan Chabardès, Patrick Mertens, Anna Castrioto, Andrea Kistner, Emmanuel Broussolle, Stéphane Thobois, Paul Krack
BACKGROUND: Subthalamic stimulation improves the motor and neuropsychiatric symptoms of Parkinson's disease. However, the impact of this treatment on impulse control and personality is the subject of heavy debate. The objective of this study was to investigate personality changes after subthalamic stimulation. METHODS: Using Cloninger's biosocial model, we assessed personality in 73 Parkinson's disease patients before and 12 months after subthalamic stimulation accompanied by a drastic reduction in dopaminergic medication...
June 23, 2017: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/28641470/do-psychosocial-predictors-affect-the-following-days-cortisol-awakening-response-expanding-the-temporal-frame-with-which-to-explore-morning-cortisol
#2
Jeffrey Proulx, Daniel Klee, Barry S Oken
Much of the extant cortisol awakening response (CAR) literature posits that CAR is an anticipatory response to perceived demands later that same day. However, expanding and switching the temporal order of cortisol and psychosocial influences may motivate more flexible approaches to understanding the dynamic relationship between mind and body, including cumulative strain on the HPA axis. This study was novel because we used two models to explore the effects of one day's emotion regulation and cortisol levels on cortisol and CAR the following day in 100 mildly stressed adults aged 50 - 81 years old, which contrasts with the more common CAR-anticipatory-response design...
June 22, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28637913/predicting-green-really-radical-plant-predictive-processing
#3
Paco Calvo, Karl Friston
In this article we account for the way plants respond to salient features of their environment under the free-energy principle for biological systems. Biological self-organization amounts to the minimization of surprise over time. We posit that any self-organizing system must embody a generative model whose predictions ensure that (expected) free energy is minimized through action. Plants respond in a fast, and yet coordinated manner, to environmental contingencies. They pro-actively sample their local environment to elicit information with an adaptive value...
June 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28630694/physical-activity-level-of-female-and-male-adult-cats-before-and-after-running-wheel-habituation
#4
Katelyn B Detweiler, Samona Rawal, Kelly S Swanson, Maria R C de Godoy
The objective of the present study was to evaluate whether access to a running wheel increases voluntary physical activity in adult female and male domestic cats. Eight neutered domestic shorthair male cats (mean age 8·6 (sd 0·05) years) and eleven intact domestic shorthair female cats (mean age 3·3 (sd 0·14) years) were group housed for 22 h daily and individually housed during the feeding period. Voluntary physical activity was measured using accelerometers. Experimental design consisted of 1 week of baseline physical activity measurement, followed by 3 weeks of wheel habituation, and 1 week of physical activity measurement post-wheel habituation...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28629458/methotrexate-induced-nausea-in-the-treatment-of-juvenile-idiopathic-arthritis
#5
REVIEW
Sonja Falvey, Lauren Shipman, Norman Ilowite, Timothy Beukelman
BACKGROUND: Methotrexate is the most commonly used disease modifying antirheumatic drug in the treatment of juvenile idiopathic arthritis and can be effective in controlling disease in many patients. MAIN BODY: A significant proportion of patients experience nausea and vomiting induced by methotrexate therapy, which can lead to decreased quality of life and discontinuation of treatment with methotrexate. Many strategies have been employed in attempts to reduce methotrexate-induced nausea, including folate supplementation, switching from oral to subcutaneous methotrexate, anti-emetic therapy, behavioral therapy, and others...
June 19, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28628005/emergence-of-visually-evoked-reward-expectation-signals-in-dopamine-neurons-via-the-superior-colliculus-in-v1-lesioned-monkeys
#6
Norihiro Takakuwa, Rikako Kato, Peter Redgrave, Tadashi Isa
Responses of midbrain dopamine (DA) neurons reflecting expected reward from sensory cues are critical for reward-based associative learning. However, critical pathways by which reward-related visual information is relayed to DA neurons remain unclear. To address this question, we investigated Pavlovian conditioning in macaque monkeys with unilateral primary visual cortex (V1) lesions (an animal model of 'blindsight'). Anticipatory licking responses to obtain juice drops were elicited in response to visual conditioned stimuli (CS) in the affected visual field...
June 19, 2017: ELife
https://www.readbyqxmd.com/read/28623778/are-there-signature-limits-in-early-theory-of-mind
#7
Ella Fizke, Stephen Butterfill, Lea van de Loo, Eva Reindl, Hannes Rakoczy
Current theory-of-mind research faces the challenge of reconciling two sets of seemingly incompatible findings: Whereas children come to solve explicit verbal false belief (FB) tasks from around 4years of age, recent studies with various less explicit measures such as looking time, anticipatory looking, and spontaneous behavior suggest that even infants can succeed on some FB tasks. In response to this tension, two-systems theories propose to distinguish between an early-developing system, tracking simple forms of mental states, and a later-developing system, based on fully developed concepts of belief and other propositional attitudes...
June 14, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28620499/intrauterine-death-following-intraamniotic-triiodothyronine-and-thyroxine-therapy-for-fetal-goitrous-hypothyroidism-associated-with-polyhydramnios-and-caused-by-a-thyroglobulin-mutation
#8
Pradeep Vasudevan, Corrina Powell, Adeline K Nicholas, Ian Scudamore, James Greening, Soo-Mi Park, Nadia Schoenmakers
In the absence of maternal thyroid disease or iodine deficiency, fetal goitre is rare and usually attributable to dyshormonogenesis, for which genetic ascertainment is not always undertaken in the UK. Mechanical complications include tracheal and oesophageal compression with resultant polyhydramnios, malpresentation at delivery and neonatal respiratory distress. We report an Indian kindred in which the proband (first-born son) had congenital hypothyroidism (CH) without obvious neonatal goitre. His mother's second pregnancy was complicated by fetal hypothyroid goitre and polyhydramnios, prompting amniotic fluid drainage and intraamniotic therapy (with liothyronine, T3 and levothyroxine, T4)...
2017: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/28619292/psychophysiological-response-in-parachute-jumps-the-effect-of-experience-and-type-of-jump
#9
Vicente Javier Clemente-Suárez, José Juan Robles-Pérez, Jesús Fernández-Lucas
We aimed to analyse the effect of experience and type of parachute jump on the psychophysiological responses of jumpers. We analysed blood oxygen saturation, heart rate, blood glucose, lactate and creatinkinase, leg strength, isometric hand strength, cortical arousal, specific fine motor skills, self-confidence and cognition, and somatic and state anxiety, before and after four different parachute jumps: a sport parachute jump, a manual tactical parachute jump, tandem pilots, and tandem passengers. Independently of the parachute jump, the psychophysiological responses of experienced paratroopers were not affected by the jumps, except for an increase in anaerobic metabolism...
June 13, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28614704/electrodermal-responses-during-appetitive-conditioning-are-sensitive-to-contingency-instruction-ambiguity
#10
Karolien van den Akker, Chantal Nederkoorn, Anita Jansen
Studies on human appetitive conditioning using food rewards can benefit from including psychophysiological outcome measures. The present study tested whether the skin conductance response can function as a measure of differential responding in an appetitive conditioning paradigm including an acquisition and extinction phase, and examined which time window during a trial is most sensitive to conditioning effects. As a secondary aim, the effects of ambiguous vs. non-ambiguous contingency instructions on conditioned responses (skin conductance responses, US expectancies, chocolate desires, and CS evaluations) were assessed...
June 11, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28601696/anticipatory-processing-in-social-anxiety-investigation-using-attentional-control-theory
#11
Rachel A Sluis, Mark J Boschen, David L Neumann, Karen Murphy
BACKGROUND AND OBJECTIVES: Cognitive models of social anxiety disorder (SAD) emphasize anticipatory processing as a prominent maintaining factor occurring before social-evaluative events. While anticipatory processing is a maladaptive process, the cognitive mechanisms that underlie ineffective control of attention are still unclear. The present study tested predictions derived from attentional control theory in a sample of undergraduate students high and low on social anxiety symptoms...
June 1, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28600160/family-based-obesity-prevention-for-infants-design-of-the-mothers-others-randomized-trial
#12
Heather M Wasser, Amanda L Thompson, Chirayath M Suchindran, Eric A Hodges, Barbara D Goldman, Eliana M Perrin, Myles S Faith, Cynthia M Bulik, M Jane Heinig, Margaret E Bentley
OBJECTIVE: Our goal is to test the efficacy of a family-based, multi-component intervention focused on infants of African-American (AA) mothers and families, a minority population at elevated risk for pediatric obesity, versus a child safety attention-control group to promote healthy weight gain patterns during the first two years of life. DESIGN, PARTICIPANTS, AND METHODS: The design is a two-group randomized controlled trial among 468 AA pregnant women in central North Carolina...
June 21, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28599740/what-nurses-need-to-know-about-immediate-postpartum-initiation-of-long-acting-reversible-contraception
#13
Debora M Dole, Jacquelyn Martin
Initiation of long-acting reversible contraception (LARC) in the immediate postpartum period is becoming more common, resulting in increased requests for early removal, primarily because of unpredictable bleeding patterns. Competing interests of healthful spacing of pregnancies, impact on breastfeeding, risks associated with pregnancy versus contraceptive method, potential adverse effects of LARC, and timing of informed consent make immediate postpartum initiation of LARC an important issue. Nearly 40% of women do not attend a postpartum visit at all, resulting in decreased initiation of contraception and increased risk of unplanned pregnancy...
June 2017: Nursing for Women's Health
https://www.readbyqxmd.com/read/28597553/attenuated-positive-psychotic-symptoms-and-the-experience-of-anhedonia
#14
Shanna Cooper, Ann M Kring, Lauren M Ellman
BACKGROUND: Deficits in anticipatory pleasure have been consistently shown among chronic, first-episode, and clinical high risk for psychosis populations, but much less attention has been given to non-clinical individuals experiencing attenuated positive psychotic symptoms (APPS). METHODS: Young adults (N = 1839) were administered the Temporal Experience of Pleasure Scale, which measures anticipatory and consummatory pleasure, and the Prodromal Questionnaire, which measures APPS...
June 9, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28597293/reducing-uncertainty-in-sustainable-interpersonal-service-relationships-the-role-of-aesthetics
#15
Ioannis Xenakis
Sustainable interpersonal service relationships (SISRs) are the outcome of a design process that supports situated meaningful interactions between those being served and those in service. Service design is not just directed to simply satisfy the ability to perceive the psychological state of others, but more importantly, it should aim at preserving these relationships in relation to the contextual requirements that they functionally need, in order to be or remain sustainable. However, SISRs are uncertain since they have many possibilities to be in error in the sense that the constructed, situated meanings may finally be proven unsuccessful for the anticipations and the goals of those people engaged in a SISR...
June 8, 2017: Cognitive Processing
https://www.readbyqxmd.com/read/28594962/effects-of-bilateral-anterior-agranular-insula-lesions-on-food-anticipatory-activity-in-rats
#16
Alex M Gavrila, Suzanne Hood, Barry Robinson, Shimon Amir
Food anticipatory activity (FAA) refers to a daily rhythm of locomotor activity that emerges under conditions of food restriction, whereby animals develop an intense, predictable period of activity in the few hours leading up to a predictable, daily delivery of food. The neural mechanisms by which FAA is regulated are not yet fully understood. Although a number of brain regions appear to be involved in regulating the development and expression of FAA, there is little evidence to date concerning the role of the anterior agranular insular cortex (AICa)...
2017: PloS One
https://www.readbyqxmd.com/read/28592695/unravelling-the-role-of-the-hippocampus-in-reversal-learning
#17
Adrià Vilà-Balló, Ernest Mas-Herrero, Pablo Ripollés, Marta Simó, Júlia Miró, David Cucurell, Diana López-Barroso, Montserrat Juncadella, Josep Marco-Pallarés, Mercè Falip, Antoni Rodríguez-Fornells
Research in reversal learning has mainly focused on the functional role of dopamine and striatal structures in driving behavior on the basis of classic reinforcement learning mechanisms. However, recent evidence indicates that beyond classic RL adaptations, individuals may also learn the inherent task structure and anticipate the occurrence of reversals. A candidate structure to support such task representation is the hippocampus, which might create a flexible representation of the environment that can be adaptively applied to goal-directed behavior...
June 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28591642/effects-of-amplitude-and-predictability-of-perturbations-to-the-arm-on-anticipatory-and-reactionary-muscle-responses-to-maintain-balance
#18
Ali Forghani, Richard Preuss, Theodore Edgar Milner
Disturbances to balance arising from forces applied to the upper limb have received relatively little attention compared to disturbances arising from support surface perturbations. In this study we applied fast ramp perturbations to the hand in anterior, posterior, medial and lateral directions. The effects of perturbation predictability and amplitude on the postural response of upper limb, trunk and lower limb muscles were investigated. Perturbations were applied either in blocks of constant amplitude and direction (predictable) or with direction and amplitude varying randomly (random) from trial to trial...
May 31, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28590412/changes-in-smoking-behavior-over-family-transitions-evidence-for-anticipation-and-adaptation-effects
#19
Damien Bricard, Stéphane Legleye, Myriam Khlat
The study of changes in smoking behaviors over the life course is a promising line of research. This paper aims to analyze the temporal relation between family transitions (partnership formation, first childbirth, separation) and changes in smoking initiation and cessation. We propose a discrete-time logistic model to explore the timing of changes in terms of leads and lags effects up to three years around the event in order to measure both anticipation and adaptation mechanisms. Retrospective biographical data from the Santé et Itinéraires Professionnels (SIP) survey conducted in France in 2006 are used...
June 7, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28588625/change-in-bmi-after-radioactive-iodine-ablation-for-graves-disease
#20
Melinda Chen, Matthew Lash, Todd Nebesio, Erica Eugster
BACKGROUND: We aimed to determine the extent of post-treatment weight gain that occurs in pediatric patients in the first year following radioactive iodine (RAI) therapy for Graves disease (GD) and its relationship to clinical characteristics. METHODS: A retrospective chart review of patients receiving RAI therapy for GD between 1998-2015 was performed. Change in BMI SDS (∆BMI SDS) from baseline to one year after treatment was determined. We also investigated whether individual clinical and/or biochemical factors were associated with the weight trajectory in these patients...
2017: International Journal of Pediatric Endocrinology
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