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https://www.readbyqxmd.com/read/20458213/acute-and-chronic-pain-management-in-fibromyalgia-updates-on-pharmacotherapy
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Eric S Hsu
Fibromyalgia (FM) is a mysterious pain syndrome with progressive and widespread pain, explicit areas of tender points, stiffness, sleep disturbance, fatigue, and psychological distress without any obvious disease. FM is commonly perceived as a condition of central pain and sensory augmentation. There are documented functional abnormalities in pain and sensory processing in FM. Central sensitization and lack of descending analgesic activity are the 2 leading mechanisms that have been demonstrated by advance in both basic and clinical research...
November 2011: American Journal of Therapeutics
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