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https://www.readbyqxmd.com/read/29142485/unexpected-inflammation-in-the-sympathetic-ganglia-in-thromboangiitis-obliterans
#1
Mahdi Farzadnia, Hassan Ravari, Mitra Masoudian, Narges Valizadeh, Bahare Fazeli
The aim of this study was to inspect more closely the microscopic and molecular sympathetic ganglia histology in thromboangiitis obliterans (TAO). The paraffin block and frozen RNAlater-treated tissue of the lumbar sympathetic ganglia of 19 TAO Caucasian male patients were evaluated. The gene expression of cluster of differentiation 4 (CD4) and cluster of differentiation 8 (CD8) markers in the frozen RNAlater-treated sympathetic ganglia tissues were evaluated by real-time polymerase chain reaction. Unexpectedly, lymphocyte infiltration was observed in all of the histological sections, ranging from scattered to moderate lymphocyte infiltration...
December 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/29140165/improved-total-body-irradiation-survival-by-delivery-of-two-radiation-mitigators-that-target-distinct-cell-death-pathways
#2
Justin Steinman, Michael Epperly, Wen Hou, John Willis, Hong Wang, Renee Fisher, Bing Liu, Ivet Bahar, Travis McCaw, Valerian Kagan, Hulya Bayir, Jian Yu, Peter Wipf, Song Li, M Saiful Huq, Joel S Greenberger
The acute lethality of total-body irradiation (TBI) involves damage to multiple organs, including bone marrow and intestine. Ionizing radiation mitigators that are effective when delivered 24 h or later after TBI include the anti-apoptotic drug, JP4-039 and the anti-necroptotic drug, necrostatin-1. In contrast to effective delivery of JP4-039 at 24 h after TBI, necrostatin-1 is most effective when delivery is delayed until 48 h, a time that correlates with the elevation of necroptosis-inducing inflammatory cytokines and necroptosis-induced serine phosphorylation of receptor-interacting serine/threonine-protein kinase-3 (RIP3) in tissues...
November 15, 2017: Radiation Research
https://www.readbyqxmd.com/read/29132181/protective-effects-of-quercetin-on-necrotizing-enterocolitis-in-a-neonatal-rat-model
#3
Selçuk Yazıcı, Cansu Unden Ozcan, Adnan Adil Hismiogullari, Fatma Bahar Sunay, Teoman Ozcan, Emel Ataş Berksoy, Elif Aksoz
No abstract text is available yet for this article.
November 13, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/29131660/biomechanical-and-morphometric-properties-of-long-flexor-tendons-of-the-toes-a-cadaver-study
#4
Orhan Beger, Gamze Tumentemür, Coşar Uzun, Elif Nedret Keskinöz, Özlem Elvan, Deniz Uzmansel, Mert Keskinbora, Nurten Erdal, Bahar Taşdelen, Zeliha Kurtoğlu
METHODS: RESULTS: CONCLUSIONS.
November 13, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/29130775/results-of-native-and-transplant-kidney-biopsies-of-children-in-a-single-center-over-a-15-years-period
#5
Emel Isiyel, Kibriya Fidan, Bahar Buyukkaragoz, Meltem Akcaboy, Yasar Kandur, Ipek Isik Gonul, Necla Buyan, Sevcan Bakkaloglu, Oguz Soylemezoglu
Renal biopsy is an important diagnostic procedure in pediatric nephrology. This study retrospectively investigates the indications, results and complications in a single tertiary children's hospital in Turkey. We evaluated the native and transplant kidney biopsies in Gazi University Pediatric Nephrology Department between 2001 and 2015. A total of 196 biopsies (144 natives and 52 transplants) were included into the study. The mean age of the patients was respectively 10.8 ± 3.5, 13.9 ± 1.5 years...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/29126366/bioactive-compounds-and-antioxidant-potential-for-polyphenol-rich-cocoa-extract-obtained-by-agroindustrial-residue
#6
Taís Vanessa Gabbay Alves, Russany Silva da Costa, Bahar Aliakbarian, Alessandro Alberto Casazza, Patrizia Perego, Mara Silvia Pinheiro Arruda, José Otávio Carréra Silva Júnior, Attilio Converti, Roseane Maria Ribeiro Costa
Processing of cocoa (Theobroma cacao L.) beans responsible for agricultural exports leads to large amounts of solid waste that were discarded, however, this one presents high contents of metabolites with biological activities. The major objective of this study was to valorise cocoa agroindustrial residue obtained by hydraulic pressing for extract rich in antioxidants. For it, the centesimal composition of residue was investigated, the green extraction was carried out from the residue after, the bioactive compounds, sugar contents and screaming by HPTLC were quantified for extract...
November 10, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29125464/off-policy-reinforcement-learning-optimal-operational-control-for-two-time-scale-industrial-processes
#7
Jinna Li, Bahare Kiumarsi, Tianyou Chai, Frank L Lewis, Jialu Fan
Industrial flow lines are composed of unit processes operating on a fast time scale and performance measurements known as operational indices measured at a slower time scale. This paper presents a model-free optimal solution to a class of two time-scale industrial processes using off-policy reinforcement learning (RL). First, the lower-layer unit process control loop with a fast sampling period and the upper-layer operational index dynamics at a slow time scale are modeled. Second, a general optimal operational control problem is formulated to optimally prescribe the set-points for the unit industrial process...
December 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/29124456/serial-immunological-parameters-in-a-phase-ii-trial-of-exemestane-and-low-dose-oral-cyclophosphamide-in-advanced-hormone-receptor-positive-breast-cancer
#8
Maryann Kwa, Xiaochun Li, Yelena Novik, Ruth Oratz, Komal Jhaveri, Jennifer Wu, Ping Gu, Marleen Meyers, Franco Muggia, James Speyer, Alyssa Iwano, Maryam Bonakdar, Lina Kozhaya, Ece Tavukcuoglu, Bahar Budan, Roy Raad, Judith D Goldberg, Derya Unutmaz, Sylvia Adams
BACKGROUND AND PURPOSE: Resistance to endocrine therapies in hormone receptor (HR)-positive breast cancer is a significant challenge. Prior studies have shown that low-dose oral cyclophosphamide can transiently deplete regulatory T cells (Tregs) and improve anti-tumor immunity. We investigated the combination of exemestane with cyclophosphamide in patients with advanced HR-positive breast cancer and assessed changes in circulating immune cell subsets. METHODS: This was a single-arm phase II trial of exemestane with cyclophosphamide in patients with metastatic HR-positive/HER2-negative breast cancer who had progressed on prior endocrine therapy (ClinicalTrials...
November 9, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29124094/a-novel-reversible-logic-gate-and-its-systematic-approach-to-implement-cost-efficient-arithmetic-logic-circuits-using-qca
#9
Peer Zahoor Ahmad, S M K Quadri, Firdous Ahmad, Ali Newaz Bahar, Ghulam Mohammad Wani, Shafiq Maqbool Tantary
Quantum-dot cellular automata, is an extremely small size and a powerless nanotechnology. It is the possible alternative to current CMOS technology. Reversible QCA logic is the most important issue at present time to reduce power losses. This paper presents a novel reversible logic gate called the F-Gate. It is simplest in design and a powerful technique to implement reversible logic. A systematic approach has been used to implement a novel single layer reversible Full-Adder, Full-Subtractor and a Full Adder-Subtractor using the F-Gate...
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29117293/patient-satisfaction-with-an-early-smartphone-based-cosmetic-surgery-postoperative-follow-up
#10
Edoardo Dalla Pozza, Gehaan F D'Souza, Anthony DeLeonibus, Brianna Fabiani, Bahar Bassiri Gharb, James E Zins
Background: While prevalent in everyday life, smartphones are also finding increasing use as a medical care adjunct. The use of smartphone technology as a postoperative cosmetic surgery adjunct for care has received little attention in the literature. Objectives: The purpose of this effort was to assess the potential efficacy of a smartphone-based cosmetic surgery early postoperative follow-up program. Specifically, could smartphone photography provided by the patient to the plastic surgeon in the first few days after surgery allay patient's concerns, improve the postoperative experience and, possibly, detect early complications? Methods: From August 2015 to March 2016 a smartphone-based postoperative protocol was established for patients undergoing cosmetic procedures...
June 1, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29114425/relationships-between-initial-probing-depth-and-changes-in-the-clinical-parameters-following-non-surgical-periodontal-treatment-in-chronic-periodontitis
#11
Suleyman Emre Meseli, Bahar Kuru, Leyla Kuru
Purpose: The aim of this study was to evaluate the relationship between initial probing depth (IPD) and changes in clinical parameters following non-surgical periodontal treatment (NPT) in chronic periodontitis patients. Subjects and Methods: A total of 1672 periodontal pockets having 3mm≤IPD≤9mm of depth in 15 chronic periodontitis patients were included. NPT consisting of oral hygiene instructions, scaling and root planing was applied in two sessions. Probing depth (PD), clinical attachment level, gingival recessions (GR) were measured before and eight weeks after treatment...
2017: J Istanb Univ Fac Dent
https://www.readbyqxmd.com/read/29114408/a-different-approach-to-the-nutritional-therapy-in-intensive-care-units-nutrition-software-icnus
#12
REVIEW
Mois Bahar
Critically ill patients receive nutritional support in addition to extensive organ support therapies in the intensive care units. The transcription of the data obtained by multiple devices from a wide spectrum of usage areas is a challenging process and is prone to errors. Software specifically designed for usage in intensive care units do offer numerous advantages. Primarily, it facilitates to improve the management of time and workflow for the benefit of patients. Therefore, we believed that a different approach was needed for the nutritional regime of our critically ill patients...
October 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/29114153/genetic-polymorphism-of-plasmodium-vivax-duffy-binding-protein-in-malarious-areas-in-southeastern-of-iran
#13
Mehdi Nateghpour, Afsaneh Motevalli Haghi, Bahare Naderi, Zargham Sepehrizadeh
Plasmodium vivax parasite causes the largest number of malaria infection in some malarious areas of the world including Iran. Considering transfer and genetic dynamics of the parasite population in a specific area can help us to predict the spread of the infection either emergence of new cases or drug resistance in the context of elimination program in the malarious areas. Study on the genetic diversity of common alleles in a given geographical area, for vaccine and immune level studies can be important. The purpose of this study was to know the status of P...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29111821/correlations-of-corneal-optical-densitometry-endothelial-hexagonality-percentage-and-epithelium-thickness
#14
Gökhan Pekel, Fatih Özbakış, Alperen Bahar, Evre Pekel, Ebru Nevin Çetin
PURPOSE: Our aim was to examine the associations between the cornea morphological parameters, endothelial cell density, and anterior chamber measurements. METHODS: This observational study included 50 eyes of 50 healthy volunteers. The thicknesses of corneal epithelium, Bowman's layer, stroma, Descemet's membrane-endothelium complex, and pre-ocular tear film were measured by means of anterior segment optical coherence tomography. The keratometry (K), corneal volume (CV), corneal optical densitometry (COD), iridocorneal angle (ICA), anterior chamber depth (ACD), and anterior chamber volume (ACV) measurements were taken by the Scheimpflug anterior segment imaging...
November 7, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29110153/protection-by-mtor-inhibition-on-zymosan-induced-systemic-inflammatory-response-and-oxidative-nitrosative-stress-contribution-of-mtor-mek1-erk1-2-ikk%C3%AE-i%C3%AE%C2%BAb-%C3%AE-nf-%C3%AE%C2%BAb-signalling-pathway
#15
Seyhan Sahan-Firat, Meryem Temiz-Resitoglu, Demet Sinem Guden, Sefika Pinar Kucukkavruk, Bahar Tunctan, Ayse Nihal Sari, Zumrut Kocak, Kafait U Malik
Mammalian target of rapamycin (mTOR), a serine/threonine kinase regulate variety of cellular functions including cell growth, differentiation, cell survival, metabolism, and stress response, is now appreciated to be a central regulator of immune responses. Because mTOR inhibitors enhanced the anti-inflammatory activities of regulatory T cells and decreased the production of proinflammatory cytokines by macrophages, mTOR has been a pharmacological target for inflammatory diseases. In this study, we examined the role of mTOR in the production of proinflammatory and vasodilator mediators in zymosan-induced non-septic shock model in rats...
November 6, 2017: Inflammation
https://www.readbyqxmd.com/read/29105395/the-effect-of-vitrification-on-expression-and-histone-marks-of-igf2-and-oct4-in-blastocysts-cultured-from-two-cell-mouse-embryos
#16
Maryam Jahangiri, Maryam Shahhoseini, Bahar Movaghar
OBJECTIVES: Vitrification is increasingly used in assisted reproductive technology (ART) laboratories worldwide. In this study the effect of vitrification on the expression and modifications of H3 histones of Igf2 and Oct4 was investigated in blastocysts cultured from vitrified and non-vitrified two-cell embryos. MATERIALS AND METHODS: In this experimental study, two-cell embryos were cultured in KSOM medium to reach the blastocyst stage. Expression of Igf2 and Oct4 and modifications of H3 histones in regulatory regions of both genes were compared with in vivo blastocysts, which comprise the control group...
January 2018: Cell Journal
https://www.readbyqxmd.com/read/29101796/children-s-meta-talk-in-their-collaborative-decision-making-with-peers
#17
Bahar Köymen, Michael Tomasello
In collaborative decision making, children must evaluate the evidence behind their respective claims and the rationality of their respective proposals with their partners. In the main study, 5- and 7-year-old peer dyads (N = 196) were presented with a novel animal. In the key condition, children in a dyad individually received conflicting information about what the animal needs (e.g., rocks vs. sand for food) from sources that differ in reliability (with first-hand vs. indirect evidence). Dyads in both age groups were able to reliably settle on the option with the best supporting evidence...
November 1, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29098401/proteinuria-in-a-male-adolescent-with-hearing-loss-answers
#18
Gülşah Kaya Aksoy, Elif Çomak, Bahar Akkaya, Mustafa Koyun, Sema Akman
No abstract text is available yet for this article.
November 2, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29098399/proteinuria-in-a-male-adolescent-with-hearing-loss-questions
#19
Gülşah Kaya Aksoy, Elif Çomak, Bahar Akkaya, Mustafa Koyun, Sema Akman
No abstract text is available yet for this article.
November 2, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29094502/association-between-uterine-position-and-transvaginal-misoprostol-treatment-for-early-pregnancy-failure
#20
Henry H Chill, Nirit Malyanker, Gilad Karavani, Rani Haj-Yahya, Shmuel Herzberg, Raz Bahar, David Shveiky, Uri P Dior
AIM: We aimed to determine the importance of uterine position as a predicting factor of success rate in medically treated early pregnancy failure (EPF). METHODS: We carried out a retrospective cohort study at the Obstetrics and Gynecology Department of a tertiary medical center between January 2011 and June 2012. We included women diagnosed with EPF, which we defined as women diagnosed with missed abortion up to 13 gestational weeks. Patients were treated with one or two doses of 800 μg of misoprostol vaginally in accordance with the department's protocol...
November 2, 2017: Journal of Obstetrics and Gynaecology Research
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