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inflamatory breast cancer

Laura M Trejo-Avila, Pablo Zapata-Benavides, Raúl Barrera-Rodríguez, Isaías Badillo-Almaráz, Santiago Saavedra-Alonso, Diana E Zamora-Avila, Karla Morán-Santibañez, Jorge A Garza-Sáenz, Reyes Tamez-Guerra, Cristina Rodríguez-Padilla
BACKGROUND: Previous studies have reported on the presence of Murine Mammary Tumor Virus (MMTV)-like gene sequences in human cancer tissue specimens. Here, we search for MMTV-like gene sequences in lung diseases including carcinomas specimens from a Mexican population. This study was based on our previous study reporting that the INER51 lung cancer cell line, from a pleural effusion of a Mexican patient, contains MMTV-like env gene sequences. RESULTS: The MMTV-like env gene sequences have been detected in three out of 18 specimens studied, by PCR using a specific set of MMTV-like primers...
2011: Virology Journal
Sumana Dakeng, Suwit Duangmano, Weena Jiratchariyakul, Yaowalak U-Pratya, Oliver Bögler, Pimpicha Patmasiriwat
The cucurbitacins are tetracyclic triterpenes found in plants of the family Cucurbitaceae. Cucurbitacins have been shown to have anti-cancer and anti-inflamatory activities. We investigated the anti-cancer activity of cucurbitacin B extracted from Thai medicinal plant Trichosanthes cucumerina Linn. Cell viability was assessed by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Results indicated that cucurbitacin B from T. cucumerina Linn. has a cytotoxic effect on breast cancer cell lines SKBR-3 and MCF-7 with an IC50 of 4...
January 2012: Journal of Cellular Biochemistry
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