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https://www.readbyqxmd.com/read/29780074/communication-site-ligation-and-polyglycolic-acid-sheet-use-for-the-treatment-of-hydrothorax-in-patients-undergoing-continuous-ambulatory-peritoneal-dialysis
#1
Hirotoshi Kubokura, Junichi Okamoto, Jitsuo Usuda
INTRODUCTION: Hydrothorax due to pleuroperitoneal communication (PPC) can occur in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). We report our experiences of the safety and efficacy of the treatment of four patients with a novel video-assisted thoracoscopy method. METHODS: Single-port video-assisted thoracoscopic surgery (VATS) was performed with a mini-thoracotomy of 5 cm in length. The PPC site was identified on the diaphragm and ligated using an endoscopic loop...
May 21, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29779821/clinical-efficacy-and-feasibility-of-whey-protein-isolates-supplementation-in-malnourished-peritoneal-dialysis-patients-a-multicenter-parallel-open-label-randomized-controlled-trial
#2
Sharmela Sahathevan, Chee-Hee Se, SeeHoe Ng, Ban-Hock Khor, Karuthan Chinna, Bak Leong Goh, Halim A Gafor, Sunita Bavanandan, Ghazali Ahmad, Tilakavati Karupaiah
BACKGROUND AND AIMS: Poor dietary intake is commonly associated with malnutrition in the dialysis population and oral nutritional supplementation is strategized to redress dietary inadequacy. Knowledge on clinical efficacy of whey protein supplementation (WPS) as an option to treat malnutrition in continuous ambulatory peritoneal dialysis (CAPD) patients is limited. METHODS: This multicenter, parallel, open-label, randomized controlled trial investigated the clinical efficacy of WPS in 126 malnourished CAPD patients with serum albumin <40 g/L and body mass index (BMI) <24 kg/m2 ...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29779030/high-intraperitoneal-interleukin-6-levels-predict-peritonitis-in-peritoneal-dialysis-patients-a-prospective-cohort-study
#3
Xiaoxiao Yang, Yijing Tong, Hao Yan, Zhaohui Ni, Jiaoqi Qian, Wei Fang
BACKGROUND: To evaluate the predictive value of dialysate interleukin-6 (IL-6) representing local subclinical intraperitoneal inflammation for the development of peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients. METHODS: Stable prevalent CAPD patients were enrolled in this prospective study. IL-6 concentration in the overnight effluent was determined and expressed as the IL-6 appearance rate (IL-6AR). Patients were divided into 2 groups according to the median of IL-6AR and prospectively followed up until the first episode of peritonitis, cessation of PD, or the end of the study (December 30, 2017)...
May 18, 2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29776936/ethambutol-and-isoniazid-induced-severe-neurotoxicity-in-a-patient-undergoing-continuous-ambulatory-peritoneal-dialysis
#4
Meijun Si, Huiqun Li, Yanru Chen, Hui Peng
Ethambutol (EMB) and isoniazid (INH) are the first-line antituberculosis (anti-TB) drugs. However, their neurotoxicity could cause adverse effect and the patients with end-stage renal disease are especially vulnerable due to the reduction in renal drug clearance. Here, we report a 36-year-old man receiving peritoneal dialysis developed progressive paralysis in lower extremities, vision loss and hoarseness 4 months after anti-TB treatment with INH, EMB and rifapentine because of concomitant pulmonary tuberculosis...
May 18, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29769597/long-term-risk-for-end-stage-kidney-disease-and-death-in-a-large-population-based-cohort
#5
Emanuel Zitt, Constanze Pscheidt, Hans Concin, Reinhard Kramar, Raphael S Peter, Jan Beyersmann, Karl Lhotta, Gabriele Nagel
Knowledge of metabolic risk factors for end-stage kidney disease (ESKD) in the general population is limited when considering the competing event death in risk analysis. The aim of our prospective observational study was to investigate how blood pressure and metabolic factors might influence the risks for ESKD and death before ESKD in a large Austrian population-based cohort with long-term follow-up. 177,255 participants (53.8% women; mean age 42.5 years) were recruited between 1988 and 2005 and linked to the Austrian Dialysis and Transplant Registry and the National Mortality Registry...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29765590/a-case-of-rhabdomyolysis-after-kidney-transplantation-successfully-managed-with-intensive-continuous-dialysis
#6
Rauf Shahbazov, Michael Fox, Jennifer L Alejo, Malik A Anjum, Feredun Azari, Alden Doyle, Avinash Agarwal, Kenneth L Brayman
Rhabdomyolysis is characterized by muscle cell death which can result in acute kidney injury from pigment nephropathy. We present a patient who developed rhabdomyolysis immediately after deceased donor kidney transplantation surgery and was managed with continuous renal replacement therapy that resulted in successful salvage of the kidney allograft. Patients who develop acute kidney failure requiring renal replacement therapy generally have a poor prognosis. It is worth noting that while continuous veno-venous hemofiltration (CVVHF) offers greater volume support and continuous clearance compared to hemodialysis (HD), recent studies have demonstrated no clinically significant improvement in clinical outcome between the two...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29762257/evaluation-of-safety-guidelines-on-the-use-of-iodinated-contrast-material-conundrum-continued
#7
Estelle C Nijssen, Patty J Nelemans, Roger J Rennenberg, Vincent van Ommen, Joachim E Wildberger
OBJECTIVES: Recently, safety guidelines for the use of intravascular iodinated contrast material have been updated, and the recommended threshold for giving prophylaxis to prevent contrast-induced nephropathy (CIN) has been reduced to estimated glomerular filtration rate (eGFR) less than 30 mL/min/1.73 m. Data on this population in the context of CIN, especially evidence for efficacy of the recommendation of prophylactic intravenous hydration, are lacking. The aim of the current study was to test implicit assumptions underlying the guideline update: (1) patients with eGFR <30 mL/min/1...
May 14, 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29760559/smoking-and-outcomes-in-kidney-transplant-recipients-a-post-hoc-survival-analysis-of-the-favorit-trial
#8
Larry A Weinrauch, Brian Claggett, Jiankang Liu, Peter V Finn, Matthew R Weir, Daniel E Weiner, John A D'Elia
Background: Tobacco use remains an international health problem with between 10% and 40% of adults currently using tobacco. Given the rising number of patients either awaiting or having received a kidney transplant and the absence of smoking cessation as the criterion for transplantation in guidelines, we explored the association between smoking status and clinical outcomes in kidney transplant recipients. Patients and methods: In this post hoc analysis of the Folic Acid for Vascular Outcome Reduction in Transplant trial, the associations between smoking status, defined as never having smoked, formerly or currently smoking, and both all-cause mortality and graft survival were assessed using Cox proportional hazards models...
2018: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/29758322/endovascular-repair-of-an-inadvertent-right-vertebral-artery-rupture-during-dialysis-catheter-insertion
#9
Kalliopi-Maria Tasopoulou, Christos Argyriou, Michael Mantatzis, Konstantia Kantartzi, Ploumis Passadakis, George S Georgiadis
Central venous (CV) catheterization is not only an invaluable diagnostic modality but also an essential therapeutic tool for the treating physician, enabling rapid and reliable intravenous administration of drugs and fluids, providing venous access to patients undergoing long-term continuous or repeated intravenous treatment such as chemotherapy or it can be used for haemodialysis in patients suffering from acute or chronic renal disease. On the other hand, CV catheterization can lead to a wide range of life-threatening complications for the patient especially if left untreated or become late-diagnosed...
May 11, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29750039/impact-of-an-inline-extracorporeal-membrane-oxygenation-hemofilter-system-in-neonatal-acute-kidney-injury
#10
Mohammed Azar, Abdulrahman Alamir, Abdullah Thabet Al Qahtani, Al Mokali Khamisa, Khalid Alfakeeh
Extracorporeal membrane oxygenation (ECMO) is considered a recognized lifesaving support for patients with cardiorespiratory failure. Acute kidney injury (AKI) and fluid overload are significant morbidity factors resulting in serious complications. The inline hemofilter system (IHS) and the continuous renal replacement therapy (CRRT) machine are different methods of renal replacement therapy for patients with ECMO. IHS is the alternate, safe dialysis modality of choice because it is user-friendly, inexpensive, and efficiently removes fluid overload and renal diffusive clearance...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29742659/anhydramnios-in-the-setting-of-renal-malformations-the-national-institutes-of-health-workshop-summary
#11
Marva Moxey-Mims, Tonse N K Raju
Anhydramnios in the setting of severe malformations of the fetal kidney and urinary tract is associated with a high incidence of stillbirths and life-threatening complications, including severe pulmonary hypoplasia, umbilical cord compression, and perinatal asphyxia. To prevent such adverse outcomes, some centers in the United States and elsewhere are offering amniotic fluid restoration for women diagnosed with anhydramnios in the setting of fetal renal malformations. The procedures include infusions of amniotic fluid substitutes (normal saline), percutaneously or through an amnioport-an implanted system for serial or continuous infusion of normal saline to maintain the desired amniotic fluid volume...
May 7, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29742515/dose-response-between-cardiovascular-risk-factors-and-cardiovascular-mortality-among-incident-peritoneal-dialysis-patients
#12
Xiaoxue Zhang, Dahai Yu, Yamei Cai, Jin Shang, Rui Qin, Jing Xiao, Xing Tian, Zhanzheng Zhao, David Simmons
BACKGROUND/AIMS: Traditional cardiovascular (CV) risk factors (RFs) and their management targets may not be applicable to specific medical subpopulations, particularly dialysis patients. This study aimed to evaluate the dose-response association between measurements of RFs, cardiovascular mortality, and potential metabolic targets among Chinese patients initializing peritoneal dialysis (PD). METHODS: Risk-set sampling was applied to two population based 1: 10 case-control studies of incident PD patients, matched by age, sex and the year of initialisation of PD: a main sample (204 cases and 2,040 controls) and a replication sample (81 cases and 810 controls)...
April 23, 2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29737362/-regional-citrate-anticoagulation-in-renal-replacement-therapy-in-the-intensive-care-station-recommendations-from-the-renal-section-of-the-dgiin-%C3%A3-giain-and-divi
#13
REVIEW
M Schmitz, M Joannidis, D Czock, S John, A Jörres, S J Klein, M Oppert, V Schwenger, J Kielstein, A Zarbock, D Kindgen-Milles, C Willam
BACKGROUND: Regional citrate anticoagulation (RCA) in continuous renal replacement therapy can effectively anticoagulate dialysis circuits without having adverse effects on systemic heparin application. In particular, in continuous renal replacement therapy RCA is well established and represents a safe procedure with longer filter lifetimes and fewer bleeding complications. OBJECTIVES: To provide guidance on the indications, advantages and disadvantages, and use of RCA, current recommendations from the renal section of the DGIIN (Deutschen Gesellschaft für Internistische Intensivmedizin und Notfallmedizin), ÖGIAIN (Österreichischen Gesellschaft für Internistische und Allgemeine Intensivmedizin und Notfallmedizin) and DIVI (Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin) are stated...
May 8, 2018: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29735820/-fusarium-the-versatile-pathogen
#14
REVIEW
Ananya Tupaki-Sreepurna, Anupma Jyoti Kindo
Fusarium is an emerging human opportunistic pathogen of growing importance, especially among immunosuppressed haematology patients due to an increased incidence of disseminated infections over the past two decades. This trend is expected only to continue due to the advances in medical and surgical technologies that will prolong the lives of the severely ill, making these patients susceptible to rare opportunistic infections. Production of mycotoxins, enzymes such as proteases, angio-invasive property and an intrinsically resistant nature, makes this genus very difficult to treat...
January 2018: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29734649/toxicological-assessment-of-a-lignin-core-nanoparticle-doped-with-silver-as-an-alternative-to-conventional-silver-core-nanoparticles
#15
Cassandra E Nix, Bryan J Harper, Cathryn G Conner, Alexander P Richter, Orlin D Velev, Stacey L Harper
Elevated levels of silver in the environment are anticipated with an increase in silver nanoparticle (AgNP) production and use in consumer products. To potentially reduce the burden of silver ion release from conventional solid core AgNPs, a lignin-core particle doped with silver ions and surface-stabilized with a polycationic electrolyte layer was engineered. Our objective was to determine whether any of the formulation components elicit toxicological responses using embryonic zebrafish. Ionic silver and free surface stabilizer were the most toxic constituents, although when associated separately or together with the lignin core particles, the toxicity of the formulations decreased significantly...
May 4, 2018: Antibiotics
https://www.readbyqxmd.com/read/29731493/current-practice-and-outcomes-of-peritoneal-dialysis-in-the-nippon-medical-school-musashi-kosugi-hospital
#16
Yuichiro Sumi, Yukinao Sakai, Koji Mugishima, Anna Suzuki, Yusuke Otsuka, Tomoyuki Otsuka, Shuichi Tsuruoka
INTRODUCTION: Various innovations for preventing complications and improving a patient's quality of life have been implemented for peritoneal dialysis (PD), which was established in Japan approximately 35 years ago and introduced at our hospital in 1999. Herein, we investigate the outcomes of patients undergoing PD to identify approaches for improving their long-term prognosis. METHODS: This retrospective study included 114 patients who underwent PD between September 1999 and August 2017 and included various parameters such as patient survival rate, technical survival rate, cause (s) of PD withdrawal, incidence of peritonitis, dialysis duration, and change in residual renal function (RRF)...
2018: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/29730948/piperacillin-population-pharmacokinetics-in-critically-ill-adults-during-sustained-low-efficiency-dialysis
#17
Salmaan Kanji, Jason A Roberts, Jiao Xie, Abdulaziz Alobaid, Sheryl Zelenitsky, Swapnil Hiremath, Guijun Zhang, Irene Watpool, Rebecca Porteous, Rakesh Patel
BACKGROUND: Sustained low-efficiency dialysis (SLED), is increasingly being used in intensive care units (ICUs) but studies informing drug dosing for such patients is lacking. OBJECTIVE: To describe the population pharmacokinetics (PKs) of piperacillin/tazobactam in critically ill adults receiving SLED and to provide dosing recommendations. METHODS: This prospective population PK study was conducted in adult ICU patients prescribed piperacillin/tazobactam while receiving SLED; 321 blood samples were obtained from 34 participants during and between approximately 50 SLED treatments for quantification of piperacillin and tazobactam concentrations in plasma...
May 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29725650/effect-of-frequent-dialysis-on-renal-recovery-results-from-the-acute-renal-failure-trial-network-study
#18
Anitha Vijayan, Rowena B Delos Santos, Tingting Li, Charles W Goss, Paul M Palevsky
Introduction: The optimal frequency of intermittent hemodialysis (IHD) in the treatment of acute kidney injury (AKI) remains unclear. Increasing the frequency of IHD, while offering the possible advantage of reduced ultrafiltration requirement and less hemodynamic instability per session, amplifies patient contact with an extracorporeal circuit with possible deleterious cardiovascular and immunological consequences. A recent study suggested that intensive renal replacement therapy (RRT) is associated with a decrease in urine output during AKI...
March 2018: KI Reports
https://www.readbyqxmd.com/read/29720873/the-impact-on-quality-of-life-of-dialysis-patients-with-renal-insufficiency
#19
Marta Dąbrowska-Bender, Grażyna Dykowska, Wioletta Żuk, Magdalena Milewska, Anna Staniszewska
Aim: The aim of the study was the subjective assessment of the quality of life (QoL) of 140 patients treated with dialysis (peritoneal dialysis and hemodialysis). Background: Chronic kidney disease and the methods of its treatment play an important part in shaping the QoL of patients receiving dialysis. As a result, kidney failure causes many limitations in patients' physical, mental, and social activities. Methods: The instrument to measure the QoL was the authors' own questionnaire made on the basis of Kidney Disease and Quality of Life Short Form version 1...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29714440/the-impact-of-visit-to-visit-systolic-blood-pressure-variability-on-residual-renal-function-and-left-ventricular-hypertrophy-in-peritoneal-dialysis-patients
#20
Jun-Ping Tian, Hong Wang, Xin-Kui Tian, Feng-He Du, Tao Wang
Background/aim: Blood pressure (BP) variability is more closely associated with adverse outcomes than ‘usual’ BP in the general population. Residual renal function (RRF) and left ventricular hypertrophy (LVH) are thought to be predictors of poor outcome in dialysis patients. However, only a few studies have focused on BP variation and its link to RRF, LVH, and outcome in peritoneal dialysis (PD) patients. Therefore, we aimed to explore the effect of visit-to-visit BP variability on RRF and LVH in continuous ambulatory PD (CAPD) patients...
April 30, 2018: Turkish Journal of Medical Sciences
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