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https://www.readbyqxmd.com/read/27900965/effect-of-intraperitoneal-injection-of-sulodexide-on-peritoneal-function-and-albumin-leakage-in-continuous-ambulatory-peritoneal-dialysis-patients
#1
Yosra Guedri, K Najla Damma, Melek Toumi, Wissal Sahtout, Awatef Azzabi, Sinda Mrabet, Safa Nouira, Dalila Saidane, Samira Amor, Anis Belarbia, Dorsaf Zellama, Abdellatif Achour
Peritoneal protein loss is one of the inevitable consequences during continuous ambulatory peritoneal dialysis (CAPD). Our objective was to study the effect of sulodexide on the protein loss and efficiency of dialysis. This study included six patients receiving CAPD treated with sulodexide at the dose of 600 IU/day given by intraperitoneal injection for 10 days. Clinical and biologic parameters were assessed before starting the treatment (D0 and after 10 days of treatment (D10. We also evaluated the benefit of therapy persisting 20 days after the end of treatment (D30...
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27893682/peritoneal-dialysis-related-peritonitis-due-to-halomonas-hamiltonii-a-first-case-report
#2
Se Hwan Yeo, Jae Hoon Kwak, Yeo Un Kim, Jin Suk Lee, Hyo Jin Kim, Kyoung Hwa Park, Jung Sook Lee, Gyoung Yim Ha, Jeong Ho Lee, Jun Yeop Lee, Kyung Don Yoo
INTRODUCTION: Halomonas hamiltonii is a Gram-negative, halophilic, motile, and nonspore-forming rod bacterium. Although most Halomonas sp. are commonly found in saline environments, it has rarely been implicated as a cause of human infection. Herein, the authors present a case report of continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis attributed to H hamiltonii. CASE PRESENTATION: An 82-year-old male patient who had been receiving CAPD therapy presented to an emergency department with complaints of abdominal pain and cloudy dialysate that had persisted for 2 days...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27891387/continuous-ambulatory-peritoneal-dialysis-catheter-tunnel-breakdown-and-its-repair
#3
Shantajit Nameirakpam, Salinita Naorem, Chetan Maibam, Sharatkumar Singh Naorem
No abstract text is available yet for this article.
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27891288/massive-ascites-in-a-renal-transplant-patient-after-laparoscopic-fenestration-of-a-lymphocele
#4
Shohei Kawaguchi, Takahiro Nohara, Takashi Shima, Satoko Matsuyama, Chikako Nose, Junya Yamahana, Yoshifumi Kadono, Chikashi Seto, Masahiko Kawabata, Atsushi Mizokami
Retroperitoneal lymphocele is a common complication of renal transplantation. Here, we report the case of a 67-year-old woman with massive ascites after fenestration surgery for a lymphocele that developed following renal transplantation. She had been on continuous ambulatory peritoneal dialysis for 9 years. Living donor renal transplantation was performed and an intrapelvic lymphocele subsequently developed. The lymphocele did not resolve after aspiration therapy; therefore, laparoscopic fenestration was performed...
2016: Case Reports in Transplantation
https://www.readbyqxmd.com/read/27886156/conformity-scores-differentiate-older-hemodialyzed-patients-and-patients-with-continuous-peritoneal-dialysis
#5
Zbigniew Nowak, Krzysztof Laudanski
BACKGROUND Conformity is a psychological variable related to the propensity of an individual to match his or her behavior and opinion to the perceived social and cultural norm, even if these do not represent the true beliefs of the person. The aim of the present study was to investigate whether the psychological variable of conformity is different in two distinct modes of renal replacement therapy (RRT) in end-stage renal disease (ESRD). MATERIAL AND METHODS A total of 56 hemodialyzed patients (HD group), 45 continuous ambulatory peritoneal dialysis patients (CAPD group) and 62 healthy volunteers (CONTR group) were enrolled in the study...
November 25, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/27883326/renal-replacement-therapy-in-patients-with-heart-and-kidney-failure
#6
Dimitrios S Goumenos, Evangelos Papachristou, Marios Papasotiriou
The incidence of chronic kidney disease (CKD) in patients with chronic heart failure (CHF) is high as CKD and CHF share underlying risk factors such as arterial hypertension, diabetes mellitus and atherosclerosis. Cardiac failure leads to renal hypoperfusion and dysfunction and then fluid overload and need for aggressive diuretic therapy. However, development of diuretic resistance represents a significant problem in the management of these patients. The role of Renal Replacement Therapy (RRT) is important for patients who do not response to conservative management of fluid overload facilitating the failing heart to restore function...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27883321/body-size-and-outcomes-in-dialysis-and-transplant-patients-does-it-matter
#7
Mehmet Sukru Sever
The terminologies of "body size", "body mass index (BMI)", "body weight", "large BMI" and "obesity" are controversial for defining the effects of "adiposity" or "fat excess" on the outcomes of dialysis and transplant patients. However, probably these terminologies will be continued to be used in the future as well, because of being older and simpler terminologies. In the general population obesity is a powerful risk factor for cardiovascular morbidity and mortality, while, it conferred a survival advantage to dialysis patients...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27882041/resolution-of-pleura-peritoneal-fistula-via-transient-daytime-ambulatory-peritoneal-dialysis-regime-dapd-8-years-follow-up
#8
Thiam Seong Christopher Lim, Kah Mean Thong
Pleural effusion or hydrothorax is a relatively rare but well-recognized complication associated with peritoneal dialysis (PD). We describe the successful long term resolution of a patient who developed pleural effusions after starting continuous ambulatory peritoneal dialysis (CAPD), by altering the PD prescription to normal volume daytime ambulatory peritoneal dialysis (DAPD) transiently before resuming the usual CAPD exchanges four months later. After 8 years of follow up, there is no sign of recurrence of the effusion...
September 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27879188/the-sustainable-kidney-care-foundation-s-contribution-to-the-improvement-of-aki-management-in-developing-countries-using-peritoneal-dialysis
#9
Mary Carter, Nathan W Levin, Calvin S Carter, John Callegari
Professional organizations, such as kidney foundations, have been active for over half a century in the field of nephrology, serving as the basic institutions for advocacy, disease education, prevention, and treatment. These organizations have focused efforts in four areas: supporting the training of clinical specialists, raising awareness about kidney disease, improving patient outcomes, and organizing continuing medical education. These activities, while essential for the success of nephrology organizations, do not usually initiate renal service programs in the neediest of places...
2016: Clinical Nephrology
https://www.readbyqxmd.com/read/27872452/how-to-treat-anca%C3%A2-associated-vasculitis-practical-messages-from-2016-eular-era%C3%A2-edta-recommendations
#10
Jan Sznajd, Chetan Mukhtyar
The European League against Rheumatism (EULAR) with the European Renal Association - European Dialysis and Transplant Association recently published an update of 2009 EULAR recommendations with a focus on the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV). In this article, we discuss the following key messages for clinical practice derived from these recommendations: 1) biopsy should be performed if possible to confirm new diagnosis or relapse; 2) glucocorticoid therapy is an extremely important adjunct to the management of AAV, but it is also responsible for the majority of adverse effects; the dose should be tapered to 7...
October 28, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27869432/-massive-hydrothorax-in-a-ease-of-hemolytic-uremic-syndrome-conservative-treatment-without-interruption-of-peritoneal-dialysis
#11
Gustavo R Marin
: The hydrothorax is a known but rare complication of acute and chronic peritoneal dialysis. Patients with hemolytic uremic syndrome seem to be more prone to this complication. Usually discontinuation of treatment is necessary due to the lack of resolution or recurrence of hydrothorax and transfer to hemodialysis, but some patients can continue dialysis with modification of technique and with resolution of hydrothorax. CASE REPORT: a child with hemolytic uremic syndrome presented a massive hydrothorax during acute peritoneal dialysis which resolved with dialysis schema modification without interruption of treatment...
December 1, 2016: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/27866963/interdialytic-weight-gain-trends-predictors-and-associated-outcomes-in-the-international-dialysis-outcomes-and-practice-patterns-study-dopps
#12
Michelle M Y Wong, Keith P McCullough, Brian A Bieber, Juergen Bommer, Manfred Hecking, Nathan W Levin, William M McClellan, Ronald L Pisoni, Rajiv Saran, Francesca Tentori, Tadashi Tomo, Friedrich K Port, Bruce M Robinson
BACKGROUND: High interdialytic weight gain (IDWG) is associated with adverse outcomes in hemodialysis (HD) patients. We identified temporal and regional trends in IDWG, predictors of IDWG, and associations of IDWG with clinical outcomes. STUDY DESIGN: Analysis 1: sequential cross-sections to identify facility- and patient-level predictors of IDWG and their temporal trends. Analysis 2: prospective cohort study to assess associations between IDWG and mortality and hospitalization risk...
November 17, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27863862/extracorporeal-membrane-oxygenation-with-multiple-organ-failure-can-molecular-adsorbent-recirculating-system-therapy-improve-survival
#13
Bailey E Sparks, Nicholas C Cavarocchi, Hitoshi Hirose
BACKGROUND: Liver dialysis, molecular adsorbent recirculating system (MARS) particularly, has been used in liver failure to bridge to transplantation. We expanded the indication for MARS to patients with acute shock liver failure and cardiopulmonary failure on extracorporeal membrane oxygenation (ECMO), aiming to improve survival to wean from ECMO. METHODS: Retrospective chart analysis of patients on ECMO between 2010 and 2015 found 28 patients who met the criteria for acute liver failure, diagnosed by hyperbilirubinemia (total bilirubin ≥10 mg/dl) or by elevated transaminase (alanine transaminase >1,000 IU/liter)...
October 7, 2016: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/27863085/pharmacokinetics-of-dabrafenib-in-a-patient-with-metastatic-melanoma-undergoing-haemodialysis
#14
John J Park, Alan V Boddy, Xiaoman Liu, David Harris, Vincent Lee, Richard F Kefford, Matteo S Carlino
The combination of dabrafenib and trametinib is a standard of care for the management of BRAF mutant metastatic melanoma. Clinical trials excluded patients with end-stage kidney disease (ESKD) and as such no data are available regarding the safety, efficacy and pharmacokinetics of these drugs in such patients. Here, we present the case of a 78 year-old male patient with ESKD managed with haemodialysis (HD), treated with dabrafenib and trametinib at reduced doses. The patient has had a partial response, and this response continues at 9 months since our last follow up without any dose escalation...
November 10, 2016: Pigment Cell & Melanoma Research
https://www.readbyqxmd.com/read/27860413/development-of-a-wearable-bioartificial-kidney-using-the-bioartificial-renal-epithelial-cell-system-brecs
#15
Kimberly A Johnston, Angela J Westover, Alvaro Rojas-Pena, Deborah A Buffington, Christopher J Pino, Peter L Smith, H David Humes
Cell therapy for the treatment of renal failure in the acute setting has proved successful, with therapeutic impact, yet development of a sustainable, portable bioartificial kidney for treatment of chronic renal failure has yet to be realized. Challenges in maintaining an anticoagulated blood circuit, the typical platform for solute clearance and support of the biological components, have posed a major hurdle in advancement of this technology. This group has developed a Bioartificial Renal Epithelial Cell System (BRECS) capable of differentiated renal cell function while sustained by body fluids other than blood...
November 18, 2016: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/27842869/isolation-and-biochemical-characterisation-of-a-bacteriocin-like-substance-produced-by-bacillus-amyloliquefaciens-an6
#16
Hanen Ben Ayed, Hana Maalej, Noomen Hmidet, Moncef Nasri
This study focuses on the isolation and characterisation of a peptide with bacteriocin-like properties from Bacillus amyloliquefaciens An6. Incubation conditions were optimised, and the effects of the incubation period and of carbon and nitrogen sources were investigated. The produced bacteriocin was partially purified with ammonium sulphate precipitation, dialysis and ultrafiltration and was then biochemically characterised. Maximum bacteriocin production was achieved after 48h of incubation in a culture medium containing 20g/L starch and 10g/L yeast extract, with an initial pH 8...
December 2015: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/27834449/finite-element-modeling-of-time-dependent-sodium-exchange-across-the-hollow-fiber-of-a-hemodialyzer-by-coupling-with-a-blood-pool-model
#17
Enrico Ravagli, Elena Grandi, Paolo Rovatti, Stefano Severi
INTRODUCTION: Hollow fiber models describe the exchange of solutes between blood and dialysate across the membrane of a single fiber of the hemodialysis filter (hemodialyzer). This work aims to develop a new approach to simulate the solute exchange in a hollow fiber in a dynamic and realistic way. Sodium was chosen as our solute of interest due to its importance in hemodialysis as an osmotic regulator. METHODS: A 2-dimensional (2D) hollow fiber model based on the finite element method (FEM) is coupled to a simple blood pool model to dynamically update the concentration of the solute entering the dialyzer...
November 11, 2016: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/27832685/treadmill-exercise-induced-e-e-elevation-as-a-predictor-of-cardiovascular-event-in-end-stage-renal-disease-on-peritoneal-dialysis
#18
Jong Ho Shin, Ki-Woon Kang, Jung Ho Kim, Jung Yeon Chin, Nae Yu Kim, Sang Hyun Park, Won Ho Kim, Yu Jeong Choi, Kyung Tae Jung
Background/Aims: Diastolic dysfunction is associated with cardiovascular (CV) events in end-stage renal disease (ESRD) on continuous ambulatory peritoneal dialysis (CAPD). However, conventional measurement of LA volume and E/e' using Doppler echocardiography has been limited to predict CV events in patients with ESRD on CAPD. Methods: From September 2007 to September 2008, 30 consecutive patients with exertional dyspnea in ESRD on CAPD and normal systolic function was prospectively enrolled and underwent laboratory testing, coronary angiography, and treadmill exercise stress echocardiography (TESE)...
November 11, 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27826207/psychosocial-predictors-of-nonadherence-to-medical-management-among-patients-on-maintenance-dialysis
#19
Fahad Dakheel Alosaimi, Mohammed Asiri, Saleh Alsuwayt, Tariq Alotaibi, Mohammed Bin Mugren, Abdulmalik Almufarrih, Saad Almodameg
BACKGROUND: A number of reports suggest a link between depression and nonadherence to recommended management for end-stage renal disease (ESRD) patients on maintenance dialysis. However, the relationship between nonadherence and other psychosocial factors have been inadequately examined. OBJECTIVES: To examine the prevalence of psychosocial factors including depression, anxiety, insecure attachment style, as well as cognitive impairment and their associations with adherence to recommended management of ESRD...
2016: International Journal of Nephrology and Renovascular Disease
https://www.readbyqxmd.com/read/27822135/chronic-kidney-disease-identification-and-management-in-primary-care
#20
REVIEW
Simon Ds Fraser, Tom Blakeman
Chronic kidney disease (CKD) is an important and common noncommunicable condition globally. In national and international guidelines, CKD is defined and staged according to measures of kidney function that allow for a degree of risk stratification using commonly available markers. It is often asymptomatic in its early stages, and early detection is important to reduce future risk. The risk of cardiovascular outcomes is greater than the risk of progression to end-stage kidney disease for most people with CKD...
2016: Pragmatic and Observational Research
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