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F Iannone, B Moretti, A Notarnicola, L Moretti, S Patella, V Patella, G Lapadula
OBJECTIVE: Extra corporeal shock waves (ESW) have been proposed as additional therapy in bone fracture repair and osteoarthrtitis (OA). However, little is known on the effects of ESW on osteoblast metabolism. The aim of this study was to evaluate phenotype changes of healthy and OA human osteoblasts following ESW treatment. METHODS: Osteoblasts were isolated from subchondral bone of 13 OA patients and 7 healthy donors. Osteoblasts were treated or not with ESW at different levels of energy and impulses...
September 2009: Clinical and Experimental Rheumatology
T Trichard, F Remy, J Girard, M Soenen, A Duquennoy, H Migaud
PURPOSE OF THE STUDY: Theoretically, long-term functional and radiographic degradation is predictable after ankle fusion, but sound evidence from the consecutive analysis of the same cohort is lacking. The purpose of this study was to check the hypothesis by repeating assessment in the same cohort of patients who underwent ankle fusion. MATERIAL AND METHODS: The cohort included 52 ankle fusions which had been analyzed in 1984 at seven years (range 2-22 years) follow-up then again in 2000 using the same evaluation criteria...
November 2006: Revue de Chirurgie Orthopédique et Réparatrice de L'appareil Moteur
C Chantelot, C Frebault, M Limousin, G Robert, H Migaud, C Fontaine
PURPOSE OF THE STUDY: We conducted this retrospective study to analyze outcome obtained in 58 cases of carpal scaphoid nonunion treated with a non-vascularized corticocancellous graft. Our objective was to search for factors influencing outcome and identify appropriate indications. MATERIAL AND METHODS: Between 1984 and 1999, 103 patients were treated with a non-vascularized corticocancellous graft. Fifty-seven patients (58 wrists) were retained for analysis (4 deaths, 30 not attending follow-up consultation far from their residence, and 12 lost to follow-up)...
December 2005: Revue de Chirurgie Orthopédique et Réparatrice de L'appareil Moteur
T Conrozier, T Saxne, C S Fan, P Mathieu, A M Tron, D Heinegård, E Vignon
OBJECTIVE: To evaluate serum concentrations of cartilage oligomeic matrix protein (COMP) and bone sialoprotein (BSP) as predictors of disease progression in hip osteoarthrtitis (OA). METHODS: Forty eight consecutive patients, referred to hospital for symptomatic hip OA, (ACR criteria) were monitored in a one year prospective trial with radiographs and serum samples. The radiographs were graded for joint space narrowing, osteophytes, and sclerosis and the joint space width was measured by a digitised image analyser...
September 1998: Annals of the Rheumatic Diseases
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