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https://www.readbyqxmd.com/read/29668026/nicu-graduates-the-role-of-the-allied-health-team-in-follow-up
#1
Jane L Orton, Joy E Olsen, Katherine Ong, Rochelle Lester, Alicia J Spittle
Infants who graduate from the neonatal intensive care unit, including those infants born preterm and/or with brain injury, are at increased risk of long-term neurodevelopmental impairments. The developmental allied health team, consisting of physical therapy, occupational therapy, and speech pathology, is crucial in early evaluation of gross motor, fine motor, feeding, and language development. Surveillance of neurodevelopment in the first year of life is essential to ensure early detection of specific developmental delays and impairments, and to ensure timely referral for early intervention...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29668025/general-movements-a-behavioral-biomarker-of-later-motor-and-cognitive-dysfunction-in-nicu-graduates
#2
Colleen Peyton, Christa Einspieler
Infants who have graduated from a neonatal intensive care unit require close follow-up because they have a greater chance of experiencing later motor and cognitive difficulties; however, these difficulties are often challenging to identify at an early age. The General Movement Assessment is a low-cost and highly reliable tool that can indicate abnormal neurological development in young high-risk infants, but it has not yet been widely implemented in the United States. In this review, we discuss the literature about the use of the General Movement Assessment in high-risk infants and how to implement the tool in a clinical setting...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29667168/cognitive-decline-and-older-driver-crash-risk
#3
Laura A Fraade-Blanar, Beth E Ebel, Eric B Larson, Jeanne M Sears, Hilaire J Thompson, Kwun Chuen G Chan, Paul K Crane
OBJECTIVES: To examine automobile crash risk associated with cognition in older drivers without dementia. DESIGN: Retrospective secondary analysis of longitudinal cohort study. SETTING: Our study used data from the Adult Changes in Thought (ACT) Study merged with Washington State crash reports and licensure records. Data were available from 2002 to 2015. PARTICIPANTS: Group Health enrollees from Washington State aged 65 and older with active driver's licenses (N=2,615)...
April 17, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29666075/rogue-one-a-story-of-tophaceous-gout-in-the-spine
#4
Karthik Dwarki, Andy Dothard, Bryan Abadie, Matthew C Miles
A 26-year-old man with history of extensive tophaceous gout presented to the referring facility with decreased bilateral lower extremity sensation and motor function that began acutely 1 week prior to admission and had progressed to urinary incontinence. The patient was admitted to the intensive care unit due to concern for sepsis secondary to epidural abscess. The patient was started on empiric vancomycin and cefepime. Neurosurgery did not recommend acute neurosurgical intervention given the lack of a compressive lesion...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29665080/clustering-of-motor-and-nonmotor-traits-in-leucine-rich-repeat-kinase-2-g2019s-parkinson-s-disease-nonparkinsonian-relatives-a-multicenter-family-study
#5
Tiago A Mestre, Claustre Pont-Sunyer, Farah Kausar, Naomi P Visanji, Taneera Ghate, Barbara S Connolly, Carmen Gasca-Salas, Drew S Kern, Jennifer Jain, Elizabeth J Slow, Achinoam Faust-Socher, Meike Kasten, Pettarusp M Wadia, Cindy Zadikoff, Prakash Kumar, Ronald M de Bie, Teri Thomsen, Anthony E Lang, Birgitt Schüle, Christine Klein, Eduardo Tolosa, Connie Marras
OBJECTIVES: The objective of this study was to determine phenotypic features that differentiate nonparkinsonian first-degree relatives of PD leucine-rich repeat kinase 2 (LRRK2) G2019S multiplex families, regardless of carrier status, from healthy controls because nonparkinsonian individuals in multiplex families seem to share a propensity to present neurological features. METHODS: We included nonparkinsonian first-degree relatives of LRRK2 G2019S familial PD cases and unrelated healthy controls participating in established multiplex family LRRK2 cohorts...
April 17, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29664176/motor-performance-in-early-life-and-participation-in-leisure-time-physical-activity-up-to-age-68-years
#6
Ahmed Elhakeem, Rebecca Hardy, David Bann, Diana Kuh, Rachel Cooper
BACKGROUND: This study examined associations between motor performance in early life and leisure-time physical activity (LTPA) participation across adulthood, and whether these changed with age. METHODS: Data were from 2526 participants from the Medical Research Council National Survey of Health and Development. Motor indicators were mother-reported ages at first standing and walking, teacher-rated games ability at age 13, and finger- and foot-tapping speed at age 15...
April 17, 2018: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/29663478/superb-microvascular-imaging-of-the-median-nerve-in-carpal-tunnel-syndrome-an-electrodiagnostic-and-ultrasonographic-study
#7
Ali Yavuz Karahan, Serdar Arslan, Banu Ordahan, Suleyman Bakdik, Timur Ekiz
OBJECTIVE: To evaluate intraneural blood flow of the median nerve using superb microvascular imaging (SMI) and power Doppler ultrasonography (PDUS), and to examine their correlation with electroneuromyography in patients with carpal tunnel syndrome (CTS). METHODS: A cross-sectional survey was used, and the study was conducted in the research unit of a training and research hospital. Patients diagnosed with CTS according to electroneuromyography studies were included in the study...
April 16, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29663403/smoke-induced-neuromuscular-junction-degeneration-precedes-the-fibre-type-shift-and-atrophy-in-copd
#8
Sophia Kapchinsky, Madhusudanarao Vuda, Kayla Miguez, Daren Elkrief, Angela R de Souza, Carolyn J Baglole, Sudhakar Aare, Norah J MacMillan, Jacinthe Baril, Paul Rozakis, Vita Sonjak, Charlotte Pion, Mylène Aubertin-Leheudre, Jose A Morais, R Thomas Jagoe, Jean Bourbeau, Tanja Taivassalo, Russell T Hepple
A neurological basis for the fast fibre shift and atrophy seen in limb muscle of patients with chronic obstructive pulmonary disease (COPD) has not been considered previously. The objective of our study was: (i) to determine if denervation contributes to fast fibre shift and muscle atrophy in COPD; and (ii) to assess using a preclinical smoking mouse model whether chronic tobacco smoke (TS) exposure could initiate denervation by causing neuromuscular junction (NMJ) degeneration. Vastus lateralis muscle biopsies were obtained from severe COPD patients (n = 10 with low fat free mass index [FFMI], 65 y; n = 15 normal FFMI, 65 y) and healthy age- and activity-matched non-smoker control subjects (CON; n = 11, 67 y), to evaluate morphological and transcriptional markers of denervation...
April 16, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29663024/neural-motor-control-differs-between-bimanual-common-goal-vs-bimanual-dual-goal-tasks
#9
Wan-Wen Liao, Jill Whitall, Joseph E Barton, Sandy McCombe Waller
Coordinating bimanual movements is essential for everyday activities. Two common types of bimanual tasks are common goal, where two arms share a united goal, and dual goal, which involves independent goals for each arm. Here, we examine how the neural control mechanisms differ between these two types of bimanual tasks. Ten non-disabled individuals performed isometric force tasks of the elbow at 10% of their maximal voluntary force in both bimanual common and dual goals as well as unimanual conditions. Using transcranial magnetic stimulation, we concurrently examined the intracortical inhibitory modulation (short-interval intracortical inhibition, SICI) as well as the interlimb coordination strategies utilized between common- vs...
April 16, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29661595/excitability-of-sensory-axons-in-amyotrophic-lateral-sclerosis
#10
José Manuel Matamala, James Howells, Thanuja Dharmadasa, William Huynh, Susanna B Park, David Burke, Matthew C Kiernan
OBJECTIVE: To evaluate the excitability of sensory axons in patients with amyotrophic lateral sclerosis (ALS). METHODS: Comprehensive sensory nerve excitability studies were prospectively performed on 28 sporadic ALS patients, compared to age-matched controls. Sensory nerve action potentials were recorded from digit 2 following median nerve stimulation at the wrist. Disease severity was measured using motor unit number estimation (MUNE), the revised ALS Functional Rating Scale (ALSFRS-R) and the MRC scale...
April 2, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29660812/tremor-severity-in-parkinson-s-disease-and-cortical-changes-of-areas-controlling-movement-sequencing-a-preliminary-study
#11
Julián Benito-León, J Ignacio Serrano, Elan D Louis, Ales Holobar, Juan P Romero, P Povalej-Bržan, Félix Bermejo-Pareja, M Dolores Del Castillo, Ignacio J Posada, Eduardo Rocon
There remains much to learn about the changes in cortical anatomy that are associated with tremor severity in Parkinson's disease (PD). For this reason, we used a combination of structural neuroimaging to measure cortical thickness and neurophysiological studies to analyze whether PD tremor was associated with cortex integrity. Magnetic resonance imaging and neurophysiological assessment were performed in 13 nondemented PD patients (9 women, 69.2%) with a clearly tremor-dominant phenotype. Cortical reconstruction and volumetric segmentation were performed with the Freesurfer image analysis software...
April 16, 2018: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/29660561/cycling-injury-risk-in-london-a-case-control-study-exploring-the-impact-of-cycle-volumes-motor-vehicle-volumes-and-road-characteristics-including-speed-limits
#12
Rachel Aldred, Anna Goodman, John Gulliver, James Woodcock
Cycling injury risk is an important topic, but few studies explore cycling risk in relation to exposure. This is largely because of a lack of exposure data, in other words how much cycling is done at different locations. This paper helps to fill this gap. It reports a case-control study of cycling injuries in London in 2013-2014, using modelled cyclist flow data alongside datasets covering some characteristics of the London route network. A multilevel binary logistic regression model is used to investigate factors associated with injury risk, comparing injury sites with control sites selected using the modelled flow data...
April 13, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29656012/muscle-strength-and-size-are-associated-with-motor-unit-connectivity-in-aged-mice
#13
Kajri A Sheth, Chitra C Iyer, Christopher G Wier, Alexander E Crum, Anna Bratasz, Stephen J Kolb, Brian C Clark, Arthur H M Burghes, W David Arnold
In older adults, the loss of muscle strength (dynapenia) and the loss of muscle mass (sarcopenia) are important contributors to the loss of physical function. We sought to investigate dynapenia, sarcopenia, and the loss of motor unit function in aging mice. C57BL/6J mice were analyzed with cross-sectional (males: 3 vs. 27 months; males and females: 8 vs. 12 vs. 20 months) and longitudinal studies (males: 10-25 months) using in vivo electrophysiological measures of motor unit connectivity (triceps surae compound muscle action potential and motor unit number estimation), in vivo measures of plantar flexion torque, magnetic resonance imaging of hind limb muscle volume, and grip strength...
March 23, 2018: Neurobiology of Aging
https://www.readbyqxmd.com/read/29652169/contribution-of-neuromuscular-factors-to-quadriceps-asymmetry-after-anterior-cruciate-ligament-reconstruction
#14
Alexa K Johnson, Riann M Palmieri-Smith, Lindsey K Lepley
CONTEXT:   To quantify quadriceps weakness after anterior cruciate ligament reconstruction (ACLR), researchers have often analyzed only peak torque. However, analyzing other characteristics of the waveform, such as the rate of torque development (RTD), time to peak torque (TTP), and central activation ratio (CAR), can lend insight into the underlying neuromuscular factors that regulate torque development. OBJECTIVE:   To determine if interlimb neuromuscular asymmetry was present in patients with ACLR at the time of clearance to return to activity...
April 13, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29651319/effects-of-perinatal-factors-on-body-mass-index-and-physical-fitness-of-school-age-children
#15
Miha Lucovnik, Gregor Starc, Petra Golja, Ivan Verdenik, Irena Stucin Gantar
Objective: To examine the effects of various maternal and neonatal perinatal factors on the child's body mass index (BMI) and physical fitness at school-age. Methods: Data from two registries, the SLOfit database (a national surveillance system of children's motor and physical development) and Slovenian National Perinatal Information System (NPIS) were analysed. Perinatal data for 2,929 children born in 2008 were linked to results of SLOfit testing of these children in 2016...
June 2018: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/29649769/sliding-window-averaging-in-normal-and-pathological-motor-unit-action-potential-trains
#16
Armando Malanda-Trigueros, Javier Navallas, Javier Rodriguez-Falces, Ignacio Rodriguez-Carreño, Sonia Porta, Miguel Fernández-Martínez, Luis Gila
OBJECTIVE: To evaluate the performance of a recently proposed motor unit action potential (MUAP) averaging method based on a sliding window, and compare it with relevant published methods in normal and pathological muscles. METHODS: Three versions of the method (with different window lengths) were compared to three relevant published methods in terms of signal analysis-based merit figures and MUAP waveform parameters used in the clinical practice. 218 MUAP trains recorded from normal, myopathic, subacute neurogenic and chronic neurogenic muscles were analysed...
March 19, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29645047/boolean-chemotaxis-of-logibots-deciphering-the-motions-of-self-propelling-microorganisms
#17
Tamanna Bhuyan, Mitradip Bhattacharjee, Amit Kumar Singh, Siddhartha Sankar Ghosh, Dipankar Bandyopadhyay
We demonstrate the feasibility of a self-propelling mushroom motor, namely a 'logibot', as a functional unit for the construction of a host of optimized binary logic gates. Emulating the chemokinesis of unicellular prokaryotes or eukaryotes, the logibots made stimuli responsive conditional movements at varied speeds towards a pair of acid-alkali triggers. A series of integrative logic operations and cascaded logic circuits, namely, AND, NAND, NOT, OR, NOR, and NIMPLY, have been constructed employing the decisive chemotactic migrations of the logibot in the presence of the pH gradient established by the sole or coupled effects of acid (HCl-catalase) and alkali (NaOH) drips inside a peroxide bath...
April 12, 2018: Soft Matter
https://www.readbyqxmd.com/read/29644615/assessment-of-the-inhalation-risks-associated-with-working-in-printing-rooms-a-study-on-the-staff-of-eight-printing-rooms-in-beijing-china
#18
Mingxing Su, Rubao Sun, Xun Zhang, Shen Wang, Ping Zhang, Zhengquan Yuan, Chao Liu, Qiang Wang
The concentration of pollution directly determines the occupational health risk, and the exposure time is an important influencing factor. We evaluated the inhalation risks of working in a printing room. Eight units with centralized printing rooms were randomly selected. Formaldehyde, ozone, benzene, toluene, xylene, and fine particulate matter were detected by spectrophotometry, gas chromatography, and direct reading instruments, respectively. The U.S. EPA inhalation risk assessment model was used to assess cancer and non-cancer risks...
April 11, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29644297/negative-pressure-in-treatment-of-persistent-post-traumatic-subcutaneous-emphysema-with-respiratory-failure-case-report-and-literature-review
#19
Jakov Mihanović, Ivan Bačić, Nina Sulen
Subcutaneous emphysema may aggravate traumatic pneumothorax treatment, especially when mechanical ventilation is required. Expectative management usually suffices, but when respiratory function is impaired surgical treatment might be indicated. Historically relevant methods are blowhole incisions and placement of various drains, often with related wound complications. Since the first report of negative pressure wound therapy for the treatment of severe subcutaneous emphysema in 2009, only few publications on use of commercially available sets were published...
February 2018: Trauma Case Reports
https://www.readbyqxmd.com/read/29643606/relationship-between-psychophysiological-factors-and-prognosis-for-activities-of-daily-living-in-patients-with-stroke-in-a-recovery-rehabilitation-unit-a-preliminary-study
#20
Shogo Kawada, Ryohei Goto
[Purpose] The objective of the present study was to examine the factors, including physical and mental functions, that are associated with the prognosis for activities of daily living in patients with stroke in a recovery rehabilitation unit. [Subjects and Methods] The subjects were 13 patients with stroke who were admitted to the recovery rehabilitation unit of Tokai Memorial Hospital between March and October 2014 and followed up for 2 months. Their physical and mental functions were evaluated at the time of admission and the relationship between these functions and activities of daily living was assessed 2 months later...
December 2017: Journal of Physical Therapy Science
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