Margherita Nosadini, Michael Eyre, Erika Molteni, Terrence Thomas, Sarosh R Irani, Josep Dalmau, Russell C Dale, Ming Lim, Banu Anlar, Thaís Armangue, Susanne Benseler, Tania Cellucci, Kumaran Deiva, William Gallentine, Grace Gombolay, Mark P Gorman, Yael Hacohen, Yuwu Jiang, Byung Chan Lim, Eyal Muscal, Alvin Ndondo, Rinze Neuteboom, Kevin Rostásy, Hiroshi Sakuma, Stefano Sartori, Suvasini Sharma, Silvia Noemi Tenembaum, Heather Ann Van Mater, Elizabeth Wells, Ronny Wickstrom, Anusha K Yeshokumar
Importance: Overall, immunotherapy has been shown to improve outcomes and reduce relapses in individuals with N-methyl-d-aspartate receptor (NMDAR) antibody encephalitis (NMDARE); however, the superiority of specific treatments and combinations remains unclear. Objective: To map the use and safety of immunotherapies in individuals with NMDARE, identify early predictors of poor functional outcome and relapse, evaluate changes in immunotherapy use and disease outcome over the 14 years since first reports of NMDARE, and assess the Anti-NMDAR Encephalitis One-Year Functional Status (NEOS) score...
November 1, 2021: JAMA Neurology