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Endobronchial tuberculosis

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https://www.readbyqxmd.com/read/28410706/conventional-tbna-experience-over-a-10-year-period-diagnostic-yield-and-associated-limitations-in-a-tertiary-care-government-set-up
#1
Varinder Saini, Kranti Garg, Uma Handa, Ritisha Bhatt
INTRODUCTION: It is challenging for pulmonologists to sample mediastinal lymph nodes or some endobronchial lesions because of safety concerns. C-TBNA (conventional transbronchial needle aspiration) is a procedure to sample such sites, but is underutilized. We present a retrospective review of patients subjected to C-TBNA through fibre-optic bronchoscopy over a 10-year period. MATERIALS AND METHODS: Year-wise statistics of C-TBNA was reviewed and results were analyzed with regard to sampling sites and type of intraluminal lesions encountered, diagnosis made and their correlation with sampling sites, sex and age...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28372894/the-additional-role-of-xpert-mtb-rif-in-the-diagnosis-of-intrathoracic-tuberculous-lymphadenitis
#2
Jinwoo Lee, Sun Mi Choi, Chang-Hoon Lee, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young Sik Park
BACKGROUND: Diagnosis of intrathoracic tuberculosis (TB) lymphadenitis remains a challenge because of difficulties in obtaining adequate tissue and the lack of a sensitive test. Recently, Xpert MTB/RIF assay is being used for rapid diagnosis of pulmonary TB, but it has not yet been widely validated in intrathoracic TB lymphadenitis. The aim of this study was to assess the additional role of Xpert MTB/RIF in diagnosing intrathoracic TB lymphadenitis using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimen...
March 31, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28355600/usefulness-of-endobronchial-ultrasound-in-patients-with-human-immunodeficiency-virus-infection-and-mediastinal-lymphadenopathy
#3
Olivia Sánchez-Cabral, Dina Martínez-Mendoza, Sebastian Fernandez-Bussy, Esmeralda Aspuru-García, Rosa Rivera-Rosales, César Luna-Rivero, José Arturo Martínez-Orozco, Gustavo Reyes-Terán
BACKGROUND: There are few published studies about the usefulness of endobronchial ultrasound (EBUS) in patients infected with human immunodeficiency virus (HIV). The clinical spectrum of likely diseases in this population is varied and differs from patients not infected with HIV. OBJECTIVE: The aim of this study was to measure the usefulness of EBUS-guided transbronchial needle aspiration (EBUS-TBNA) in HIV-infected patients with mediastinal lymphadenopathy. MATERIALS AND METHODS: We conducted an observational, cross-sectional, retrospective, descriptive study on patients with HIV infection and mediastinal lymphadenopathy who underwent EBUS-TBNA between September 2014 and April 2016...
March 30, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28355597/endobronchial-valve-used-as-salvage-therapy-in-a-mechanically-ventilated-patient-with-intractable-life-threatening-haemoptysis
#4
Usha Lalla, Brian W Allwood, Soumitra Sinha Roy, Elvis M Irusen, Coenraad F N Koegelenberg
Treatment options for intractable life-threatening haemoptysis in mechanically ventilated patients with structural lung disease who do not respond to bronchial artery embolisation (BAE) and who are deemed unfit for surgery are limited. A 26-year-old HIV-positive male with a poorly preserved CD4 count and active pulmonary tuberculosis was intubated and mechanically ventilated for persistent life-threatening haemoptysis. Two attempts at BAE failed, and life-threatening haemoptysis recurred daily for 14 days despite antituberculous therapy...
March 30, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28271046/tuberculosis-presenting-as-bronchoesophageal-fistula
#5
Santhosh Narayanan, Shiji P V, Abdul Majeed K A, Udayabhaskaran V
We report a case of bronchoesophageal fistula associated with tuberculosis. A 25 year old woman presented to us with 3 month history of cough worsening with deglutition. Radiological examination revealed mediastinal lymphadenopathy and bronchoscopy with esophagoscopy confirmed the presence of fistulous communication with features of endobronchial tuberculosis. Histological examination of bronchial biopsy specimen showed non necrotic granuloma with the PCR positive for Mycobacterium tuberculosis in her bronchial secretions...
2017: IDCases
https://www.readbyqxmd.com/read/28270942/solitary-endobronchial-papilloma-with-malignant-transformation-and-concomitant-tb-infection-case-report-and-literature-review
#6
Mohammed Al Ghobain
We are reporting a case of solitary endobronchial papilloma located in posterior segment of the left upper lobe of the lung with malignant transformation and negative human papilloma virus (HPV) strains in a 40-year-old Saudi nonsmoker man. The patient had a concomitant tuberculosis (TB) infection. The patient received appropriate treatment in the form of anti-TB medication and surgical resection of the squamous cell carcinoma followed by chemotherapy. There was no evidence of tumor recurrence, resulting in a complete cure...
2017: Case Reports in Pulmonology
https://www.readbyqxmd.com/read/28203440/tracheobronchial-tuberculosis-a-clinical-review
#7
REVIEW
Wen Ting Siow, Pyng Lee
Endobronchial tuberculosis (EBTB) is defined as tuberculous infection of the tracheobronchial tree. The exact pathogenesis is unclear, and it has a heterogenous clinical course. Its diagnosis requires the clinician to have a high index of suspicion based on clinical symptoms and radiological features. Computed tomography and bronchoscopy are useful tools in its evaluation. The goal of treatment is in the eradication of tuberculous bacilli with appropriate anti-tuberculous therapy. Use of corticosteroids is controversial for the prevention of tracheobronchial stenosis...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28166918/the-concomitant-occurrence-of-pulmonary-tuberculosis-with-bronchial-anthracofibrosis
#8
Shekhar Kunal, Ashok Shah
BACKGROUND: Bronchial anthracofibrosis (BAF), diagnosed bronchoscopically, is a clinical entity which is now beginning to emerge from obscurity. This is commonly encountered in elderly females with history of long-standing exposure to biomass fuel smoke in poorly ventilated kitchens. As awareness of BAF has increased in recent times, distinct clinicoradiological and bronchoscopic features of the disease have emerged. Diagnosis is achieved by visualisation of bluish-black mucosal hyperpigmentation along with narrowing/distortion of the affected bronchus on fibreoptic bronchoscopy (FOB)...
January 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28162798/-endobronchial-tuberculosis
#9
E Manal, Z Nahid, B Hanane, Y Najiba
BACKGROUND/AIM: The endobronchial tuberculosis (EBTB) is an uncommon type of tuberculosis. The respiratory symptoms in EBTB are usually nonspecific and misleading. The aim of the study is to determine the clinical features and diagnostic aspects of EBTB. PATIENTS AND METHODS: Twenty-eight cases of endobronchial tuberculosis collected from January 2009 to October 2015. RESULTS: EBTB was found in 16 females and 12 males. The mean age was 48 years...
April 2017: Revue de Pneumologie Clinique
https://www.readbyqxmd.com/read/28149579/endobronchial-tuberculosis-a-review
#10
REVIEW
Talha Shahzad, Muhammad Irfan
Endobronchial tuberculosis (EBTB) is a tuberculous infection of the tracheobronchial tree with microbial and histopathological evidence. Patients may present with symptoms secondary to disease itself or from the complication of disease like endobronchial obstruction. Diagnosis requires a high index of suspicion. Computed tomography (CT) and bronchoscopy along with microbiological investigations are the most useful diagnostic tools for the confirmation as well as for the evaluation of the tracheobronchial stenosis...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28107788/the-indications-and-role-of-paediatric-bronchoscopy-in-a-developing-country-with-high-prevalence-of-pulmonary-tuberculosis-and-hiv
#11
Irwin Webster, Pierre Goussard, Robert Gie, Jacques Janson, Gawie Rossouw
BACKGROUND: Bronchoscopy, an important investigation for the diagnosis and management of respiratory diseases, is widely used in high income countries. There is limited information on value of paediatric bronchoscopy in low and middle income countries (LMIC). AIMS AND OBJECTIVES: Aim was to describe the indications, findings and complications of bronchoscopy in a middle income country with a high prevalence of tuberculosis and HIV. METHODOLOGY: A retrospective analysis of a database over a 3...
January 20, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28066590/comparison-of-radial-endobronchial-ultrasound-with-a-guide-sheath-and-with-distance-by-thin-bronchoscopy-for-the-diagnosis-of-peripheral-pulmonary-lesions-a-prospective-randomized-crossover-trial
#12
Su-Juan Zhang, Ming Zhang, Jun Zhou, Qiu-Di Zhang, Qian-Qian Xu, Xiong Xu
BACKGROUND: Transbronchial biopsy (TBB) using radial endobronchial ultrasound with a guide sheath (REBUS-GS) has improved the diagnosis of peripheral pulmonary lesions (PPLs). Because of the high cost of the GS, REBUS with distance (REBUS-D) has certain advantages. The aim of this study was to compare the diagnostic yield of the REBUS-GS and REBUS-D by thin bronchoscopy for PPLs. METHODS: Patients with PPLs were enrolled in a prospective randomized crossover study from August 2014 and July 2015...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28043486/tuberculosis-in-children
#13
Ali Akbar Velayati
Tuberculosis (TB) is the main cause of infection-related death in the world. Children make up ∼5-15% of all TB cases. Severe forms of disease such as meningitis and disseminated form are more common in children. Due to current estimates of World Health Organization (WHO) in 2015, one million children suffer from TB around the world; of these, it is estimated that more than 136,000 die a year. One study estimated 67million children with latent TB which develops to active form with the rate of ∼850,000 each year...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28029667/outcomes-bronchoscopic-evaluation-in-a-university-hospital
#14
R H Ghimire, N Bhatta, P Koirala, B Bista, D R Misra, B Shah
INTRODUCTION: Study of clinical profile of the patients and diagnostic yield of the selected bronchoscopic procedures gives us important information in clinical decision making and better patient care. There are hardly very few studies regarding these entities. Therefore, we decided to study clinical characteristics and outcomes of the patients who underwent bronchoscopic evaluation in our setting. METHODS: This was a cross-sectional study the consecutive patients who underwent bronchoscopy from 1st May 2013- 30th April 2015 in division of pulmonary, critical care and sleep medicine...
October 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27882677/utility-of-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-diagnosing-non-specific-inflammatory-intrathorcacic-lymphadenitis
#15
Huizhen Yang, Shenglan Wang, Jiajun Teng, Baohui Han, Jiayuan Sun
BACKGROUND AND OBJECTIVE: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a minimally invasive technique for diagnosing intrathoracic malignancies and some benignancies; however, there are no data available on the utility of EBUS-TBNA for the diagnosis of non-specific inflammatory intrathoracic lymphadenitis. METHODS: A prospective analysis was performed from 104 patients with enlarged lymphadenopathy suspected of non-specific lymphadenitis referred for EBUS-TBNA between October 2009 and March 2012...
November 7, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27805323/identification-of-specific-ebus-sonographic-characteristics-for-predicting-benign-mediastinal-lymph-nodes
#16
Irfan Ismail Ayub, Anant Mohan, Karan Madan, Vijay Hadda, Deepali Jain, G C Khilnani, Randeep Guleria
OBJECTIVE: Reliable differentiation of benign from malignant mediastinal lymphadenopathy is important, especially in countries with a high tuberculosis burden. We hypothesized that specific sonographic features on endobronchial ultrasonography (EBUS) may differentiate benign from malignant nodes. In this study, the sonographic features of non-malignant and malignant nodes were compared. METHODS: This was a retrospective analysis of patients with intrathoracic lymphadenopathy who underwent EBUS-guided transbronchial needle aspiration (TBNA)...
November 2, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27776598/endobronchial-valve-treatment-of-destructive-multidrug-resistant-tuberculosis
#17
A Levin, S Sklyuev, I Felker, E Tceymach, D Krasnov
BACKGROUND: In accordance with the existing hypothesis, the application of an endobronchial valve (EbV) leads to selective curative atelectasis of the affected part of the lung, contributing to early closure of cavities. OBJECTIVE: To assess the effect of EbV treatment on the course of tuberculosis (TB). METHODS: We compared the efficacy of EbV treatment and complex second-line treatment in treating patients with destructive pulmonary multidrug-resistant TB (MDR-TB)...
November 2016: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/27764010/endobronchial-silicosis-and-tuberculosis-presenting-as-the-right-middle-lobe-syndrome
#18
James J Anderson, Kwun M Fong, David B Godbolt, Steven C Leong, Henry M Marshall
No abstract text is available yet for this article.
October 2016: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27758992/role-of-xpert-mtb-rif-in-differentiating-tuberculosis-from-sarcoidosis-in-patients-with-mediastinal-lymphadenopathy-undergoing-ebus-tbna-a-study-of-147-patients
#19
COMPARATIVE STUDY
Sahajal Dhooria, Nalini Gupta, Amanjit Bal, Inderpaul Singh Sehgal, Ashutosh Nath Aggarwal, Sunil Sethi, Digambar Behera, Ritesh Agarwal
BACKGROUND: In patients with intrathoracic lymphadenopathy, differentiating tuberculosis from sarcoidosis is often difficult. We hypothesized that Xpert MTB/RIF assay, a semi-automated hemi-nested PCR would help in this regard. OBJECTIVE: To evaluate the performance of Xpert MTB/RIF in the differential diagnosis of tuberculosis and sarcoidosis. METHODS: This was a retrospective analysis of patients with intrathoracic lymphadenopathy who underwent endobronchial ultrasound (EBUS)-guided transbronchial needle aspiration (TBNA), and were diagnosed as either tuberculosis or sarcoidosis...
October 7, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/27728916/lobar-collapse-therapy-using-endobronchial-valves-as-a-new-complementary-approach-to-treat-cavities-in-multidrug-resistant-tuberculosis-and-difficult-to-treat-tuberculosis-a-case-series
#20
Lorenzo Corbetta, Ariela Tofani, Flavio Montinaro, Lucio Michieletto, Loris Ceron, Chiara Moroni, Pier Giorgio Rogasi
BACKGROUND: The poor treatment outcomes of multidrug-resistant tuberculosis (TB) and the emergence of extensively drug-resistant TB and extremely and totally drug-resistant TB highlight the urgent need for new antituberculous drugs and other adjuvant treatment approaches. OBJECTIVES: We have treated cavitary tuberculosis by the application of endobronchial one-way valves (Zephyr®; Pulmonx Inc., Redwood City, Calif., USA) to induce lobar volume reduction as an adjunct to drug treatment...
2016: Respiration; International Review of Thoracic Diseases
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