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https://www.readbyqxmd.com/read/28812775/polymorphic-light-eruption-and-il-1-family-members-any-difference-with-allergic-contact-dermatitis
#1
S Lembo, G Caiazzo, N Balato, G Monfrecola, V Patra, P Wolf, A Balato
Polymorphic light eruption (PLE) is described as a delayed-type hypersensitivity reaction (DTHR) toward a de novo light-induced antigen, yet to be identified. In effect, the inflammatory pathways of PLE and allergic contact dermatitis (ACD) share common patterns in terms of the mediators involved from the innate and adaptive immune system participating in the DTHR. As we have previously highlighted the role of interleukin (IL)-1 family members in ACD, we hypothesised that the same mediators could have similar functions in PLE...
August 16, 2017: Photochemical & Photobiological Sciences
https://www.readbyqxmd.com/read/28811110/characterizing-the-diagnosis-and-treatment-of-allergic-contact-dermatitis-to-2-octyl-cyanoacrylate-used-for-skin-closure-in-elective-orthopedic-surgery
#2
Brian P Chalmers, Heath P Melugin, Peter K Sculco, Jennifer J Schoch, Rafael J Sierra, Mark W Pagnano, Michael J Stuart, Michael J Taunton
BACKGROUND: While studies have shown that postoperative wound complications can predispose to deep infection following orthopedic surgery, the best form of skin closure has not been elucidated. Furthermore, the unique risks and benefits of each type of wound closure have not been studied. The goal of this study is to present the diagnosis and treatment of patients with allergic contact dermatitis (ACD) from 2-octyl cyanoacrylate, a skin adhesive commonly used in wound closure. METHODS: Twenty-nine patients with ACD to 2-octyl cyanoacrylate (Prineo, Ethicon, NJ) following elective orthopedic surgeries from 2013 to 2016 were retrospectively reviewed; this occurred in 29 of 6088 units of Prineo used at our institution, for an estimated incidence of 0...
July 18, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28807557/the-role-of-toll-like-receptor-3-in-chronic-contact-hypersensitivity-induced-by-repeated-elicitation
#3
Risa Yasuike, Risa Tamagawa-Mineoka, Mayumi Ueta, Naomi Nakamura, Shigeru Kinoshita, Norito Katoh
BACKGROUND: Accumulating evidence suggests that Toll-like receptor (TLR)-3 signaling is involved in non-infectious immune and inflammatory reactions as well as in viral infections. The skin of patients with atopic dermatitis (AD) is often infected with virus and bacteria, leading to the aggravation of atopic symptoms. These findings suggest TLR3 signaling may be involved in the pathogenesis of AD, but the exact role of TLR3 in AD remains to be defined. OBJECTIVE: The purpose of this study was to investigate the role of TLR3 in chronic contact hypersensitivity reactions induced by repeated elicitation, resembling the features of AD...
August 4, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28807414/transient-receptor-potential-vanilloid-4-expressing-macrophages-and-keratinocytes-contribute-differentially-to-allergic-and-nonallergic-chronic-itch
#4
Jialie Luo, Jing Feng, Guang Yu, Pu Yang, Madison R Mack, Junhui Du, Weihua Yu, Aihua Qian, Yujin Zhang, Shenbin Liu, Shijin Yin, Amy Xu, Jizhong Cheng, Qingyun Liu, Roger G O'Neil, Yang Xia, Liang Ma, Susan M Carlton, Brian S Kim, Kenneth Renner, Qin Liu, Hongzhen Hu
BACKGROUND: Chronic itch is a highly debilitating symptom that underlies many medical disorders with no universally effective treatments. Although unique neuronal signaling cascades in the sensory ganglia and spinal cord have been shown to critically promote the pathogenesis of chronic itch, the role of skin-associated cells remains poorly understood. OBJECTIVE: We sought to examine the cutaneous mechanisms underlying transient receptor potential vanilloid 4 (TRPV4)-mediated allergic and nonallergic chronic itch...
August 5, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28804907/allergic-contact-dermatitis-caused-by-isobornyl-acrylate-in-freestyle%C3%A2-libre-a-newly-introduced-glucose-sensor
#5
Anne Herman, Olivier Aerts, Marie Baeck, Magnus Bruze, Christophe De Block, An Goossens, Nils Hamnerius, Sara Huygens, Dominique Maiter, Dominique Tennstedt, Bernard Vandeleene, Martin Mowitz
BACKGROUND: Glucose sensors, such as FreeStyle® Libre, are innovative medical devices developed for diabetes patients as a replacement for classic glucose meters, ensuring continuous glucose monitoring without the disadvantage of regular skin finger pricks. OBJECTIVES: To report several cases of allergic contact dermatitis caused by FreeStyle® Libre, and to report on isobornyl acrylate as a culprit allergen. PATIENTS AND METHODS: Fifteen patients presented with allergic contact dermatitis caused by FreeStyle® Libre...
August 14, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28795430/occupational-contact-urticaria-and-protein-contact-dermatitis-causes-and-concomitant-airway-diseases
#6
Eva Helaskoski, Hille Suojalehto, Outi Kuuliala, Kristiina Aalto-Korte
BACKGROUND: Contact urticaria (CU) and protein contact dermatitis (PCD) are mainly induced by an immediate, IgE-mediated immunological mechanism. Immediate sensitization is also linked to asthma and/or allergic rhinitis. OBJECTIVES: To report causes of work-induced CU and PCD, and to evaluate the occurrence of concomitant airway diseases. METHODS: We retrospectively reviewed the patient files of cases diagnosed with CU or PCD at the Finnish Institute of Occupational Health during 1995-2011...
August 10, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28790790/an-observational-study-on-the-effects-of-aviation-turbine-fuel-and-lubricants-on-the-skin-of-indian-air-force-ground-crew-in-flying-stations
#7
S Radhakrishnan, Ajay Chopra, Debdeep Mitra, R Gnanasekaran, R Kanagaraj
BACKGROUND: Ground crew of the Air Force routinely handle aviation turbine fuel (ATF) and lubricants and a need was felt to study the adverse effects of these substances on their skin so that remedial measures could be taken to prevent these adverse effects. METHODS: A multi-centric, cross-sectional, observational study was performed at three Air Force flying stations. 109 ground crew members of the Indian Air Force (IAF) who were in direct contact with ATF and lubricants were screened for dermatological manifestations on exposed areas...
July 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28790058/severe-allergic-contact-dermatitis-due-to-polysporin
#8
Sophia Colantonio, Carly Kirshen
No abstract text is available yet for this article.
August 8, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28783680/arc-arg3-1-governs-inflammatory-dendritic-cell-migration-from-the-skin-and-thereby-controls-t-cell-activation
#9
Friederike Ufer, Pablo Vargas, Jan Broder Engler, Joseph Tintelnot, Benjamin Schattling, Hana Winkler, Simone Bauer, Nina Kursawe, Anne Willing, Oliver Keminer, Ora Ohana, Gabriela Salinas-Riester, Ole Pless, Dietmar Kuhl, Manuel A Friese
Skin-migratory dendritic cells (migDCs) are pivotal antigen-presenting cells that continuously transport antigens to draining lymph nodes and regulate immune responses. However, identification of migDCs is complicated by the lack of distinguishing markers, and it remains unclear which molecules determine their migratory capacity during inflammation. We show that, in the skin, the neuronal plasticity molecule activity-regulated cytoskeleton-associated protein/activity-regulated gene 3.1 (Arc/Arg3.1) was strictly confined to migDCs...
September 23, 2016: Science Immunology
https://www.readbyqxmd.com/read/28780897/skin-diseases-of-the-vulva-eczematous-diseases-and-contact-urticaria
#10
Freja Lærke Sand, Simon Francis Thomsen
Skin diseases in the vulvar area include a variety of disorders many of which have a chronic course with significant morbidity. It is important to be aware of the symptoms, signs and diagnostic tools in order to optimise treatment. Herein, the most common eczematous diseases of the vulvar area, i.e. lichen simplex chronicus, seborrhoeic dermatitis, atopic dermatitis, irritant contact dermatitis, and non-systemic and systemic allergic contact dermatitis are reviewed. Allergic contact urticaria is also described...
August 7, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28776709/allergic-contact-dermatitis-caused-by-dimethylthiocarbamylbenzothiazole-sulfide-dmtbs-in-canvas-shoes-in-search-of-the-culprit-allergen
#11
Marie L Schuttelaar, Joost M Meijer, Malin Engfeldt, Hilde Lapeere, An Goossens, Magnus Bruze, Christina Persson, Ola Bergendorff
BACKGROUND: During rubber vulcanization, new compounds can be formed. OBJECTIVES: To report a case of allergic shoe dermatitis in which the search for the allergen ultimately led to the identification of dimethylthiocarbamylbenzothiazole sulfide (DMTBS). METHODS: A female presented with eczema on her feet after wearing Sperry Top Sider® canvas sneakers. Patch testing was performed with the European baseline series, additional series, shoe materials, and extracts of shoe materials...
August 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28771172/development-of-novel-faster-dissolving-microneedle-patches-for-transcutaneous-vaccine-delivery
#12
Akihiko Ono, Sayami Ito, Shun Sakagami, Hideo Asada, Mio Saito, Ying-Shu Quan, Fumio Kamiyama, Sachiko Hirobe, Naoki Okada
Microneedle (MN) patches are promising for transcutaneous vaccination because they enable vaccine antigens to physically penetrate the stratum corneum via low-invasive skin puncturing, and to be effectively delivered to antigen-presenting cells in the skin. In second-generation MN patches, the dissolving MNs release the loaded vaccine antigen into the skin. To shorten skin application time for clinical practice, this study aims to develop novel faster-dissolving MNs. We designed two types of MNs made from a single thickening agent, carboxymethylcellulose (CMC) or hyaluronan (HN)...
August 3, 2017: Pharmaceutics
https://www.readbyqxmd.com/read/28766805/severe-allergic-contact-dermatitis-caused-by-octylisothiazolinone-in-a-leather-sofa-two-new-cases
#13
Nadia Raison-Peyron, Emmanuelle Amsler, Catherine Pecquet, Aurélie Du-Thanh, Tania Naessens, Sandra Apers, Olivier Aerts
No abstract text is available yet for this article.
September 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28766804/allergic-contact-dermatitis-caused-by-resorcinol-following-a-temporary-black-henna-tattoo
#14
Emma Ormerod, Thomas M Hughes, Natalie Stone
No abstract text is available yet for this article.
September 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28766800/allergic-contact-dermatitis-caused-by-clindamycin-mimicking-retinoid-flare
#15
Paolo Romita, Grazia Ettorre, Monica Corazza, Alessandro Borghi, Caterina Foti
No abstract text is available yet for this article.
September 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28766799/occupational-facial-contact-dermatitis-caused-by-methylchloroisothiazolinone-methylisothiazolinone-in-a-stainless-steel-aerosol-spray
#16
Tanja Todberg, Morten S Opstrup, Jeanne D Johansen, Marianne Hald
No abstract text is available yet for this article.
September 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28766797/allergic-contact-dermatitis-caused-by-benzoic-acid-and-lauryl-glucoside-in-a-sunscreen
#17
María I Martínez-González, Ricardo González-Pérez, Irene García-Rio, Sonia Heras-González
No abstract text is available yet for this article.
September 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28766795/allergic-contact-dermatitis-caused-by-%C3%AF%C2%B5-aminocaproic-acid-in-a-purified-sodium-hyaluronate-ophthalmic-solution
#18
Shinji Mitsuyama, Fumihito Abe, Masaaki Kimura, Tetsuya Higuchi
No abstract text is available yet for this article.
September 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28762515/elr-chemokine-mediated-neutrophil-recruitment-is-involved-in-2-4-6-trinitrochlorobenzene-induced-contact-hypersensitivity
#19
Hiroyasu Sakai, Saori Yabe, Ken Sato, Yuki Kai, Fumiaki Sato, Tetsuro Yumoto, Yuka Inoue, Minoru Narita, Kenjiro Matsumoto, Shinichi Kato, Yoshihiko Chiba
Contact dermatitis is a form of delayed-type hypersensitivity characterized by localized thickening, papules, redness and vesicles of the skin. A model of contact dermatitis involving repeated challenge of a hapten is adapted to assess dermatitis as characterized by skin thickening. Recently, it was reported that neutrophils have crucial roles in contact hypersensitivity. We thus examined the involvement of CXC chemokines bearing the glutamic acid-leucine-arginine (ELR) motif ("ELR(+) chemokines") and neutrophils in the ear swelling induced by 2,4,6-trinitrochlorobenzene (TNCB) challenges in the present study...
August 1, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28761918/systemic-contact-dermatitis-to-a-surgical-implant-presenting-as-red-decorative-tattoo-reaction
#20
Hana K Cobb, Michi M Shinohara, Jason T Huss, Marshall P Welch, Jennifer M Gardner
No abstract text is available yet for this article.
July 2017: JAAD Case Reports
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