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(Contact dermatitis)

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https://www.readbyqxmd.com/read/28342908/intestinal-dendritic-cell-licensing-through-tlr4-is-required-for-oral-tolerance-in-allergic-contact-dermatitis
#1
Feriel Hacini-Rachinel, Mercedes Gomez de Agüero, Reem Kanjarawi, Ludovic Moro-Sibilot, Jean-Benoit Le Luduec, Claire Macari, Gilles Boschetti, Emilie Bardel, Philippe Langella, Bertrand Dubois, Dominique Kaiserlian
BACKGROUND: Induction of oral tolerance to haptens is an efficient way to prevent allergic contact dermatitis (ACD) in mice. Toll-like receptor (TLRs)-mediated sensing of the microbiota contributes to gut homeostasis, yet whether it contributes to induction of oral tolerance has not been documented. OBJECTIVE: We examined whether oral tolerance to the contact sensitizer DNFB depends on microbiota/TLRs and evaluated the role of TLR4 on the tolerogenic function of intestinal dendritic cells (DCs)...
March 22, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28338543/clinical-study-of-124-patients-having-perianal-dermatitis
#2
Alfredo-Daniel Agulló-Pérez, Marcos Hervella-Garcés, Saioa Oscoz-Jaime, Maialen Azcona-Rodríguez, Mónica Larrea-García, Juan-Ignacio Yanguas-Bayona
BACKGROUND: Perianal complaints are often consulted in dermatology clinics, and in many cases, a conclusive diagnosis is not easily made. OBJECTIVE: The aim of this study was to study and identify the epidemiological, clinical, and contact allergy features of patients with perianal dermatitis who attended at a contact dermatitis unit in a tertiary hospital in Spain. METHODS: Adult patients with long-lasting (>4 weeks) perianal dermatitis were recruited during the past 10 years for investigation and follow-up...
March 23, 2017: Dermatitis
https://www.readbyqxmd.com/read/28338542/multicenter-patch-testing-with-methylisothiazolinone-and-methylchloroisothiazolinone-methylisothiazolinone-within-the-international-contact-dermatitis-research-group
#3
Marléne Isaksson, Iris Ale, Klaus E Andersen, Peter Elsner, Chee-Leok Goh, An Goossens, Hemangi Jerajani, Kayoko Matsunaga, John McFadden, Magnus Bruze
BACKGROUND: The preservatives methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) and MI are well-known contact sensitizers. Recently, an increase in the contact allergy frequency for MI 0.2% aqueous (aq) has been seen in many European countries paralleled with an increase in MCI/MI allergy. Many of the MI-allergic patients do not react to MCI/MI 0.01% or 0.02% because the concentration of MI in these preparations is too low (25 and 50 ppm, respectively) to elicit a positive patch test reaction...
March 23, 2017: Dermatitis
https://www.readbyqxmd.com/read/28338541/intralesional-treatment-with-5-fluorouracil-and-steroid-improves-allergic-contact-dermatitis-without-causing-skin-atrophy-and-rebound-lesions
#4
Xiangming Chen, Guojiang Wang, Qingwen Zeng, Haiqing Zhang, Yang Hu, Aihua Yu, Ting Li
No abstract text is available yet for this article.
March 23, 2017: Dermatitis
https://www.readbyqxmd.com/read/28338540/occupational-contact-dermatitis-in-north-american-print-machine-operators-referred-for-patch-testing-retrospective-analysis-of-cross-sectional-data-from-the-north-american-contact-dermatitis-group-1998-to-2014
#5
Erin M Warshaw, Solveig L Hagen, Donald V Belsito, Joel G DeKoven, Howard I Maibach, C G Toby Mathias, Kathryn A Zug, Denis Sasseville, Matthew J Zirwas, Joseph F Fowler, Anthony F Fransway, Vincent A DeLeo, James G Marks, Melanie D Pratt, James S Taylor
BACKGROUND: Little is known about the epidemiology of contact dermatitis (CD) in print machine operators (PMOs). OBJECTIVE: The aims of this study were to estimate the prevalence of CD and characterize clinically relevant and occupationally related allergens among PMOs undergoing patch testing. METHODS: This was a retrospective cross-sectional analysis of the North American Contact Dermatitis Group data from 1998 to 2014. RESULTS: Of 39,332 patch-tested patients, 132 (0...
March 23, 2017: Dermatitis
https://www.readbyqxmd.com/read/28338538/allergenic-ingredients-in-facial-wet-wipes
#6
Kelly A Aschenbeck, Erin M Warshaw
BACKGROUND: Allergic contact dermatitis commonly occurs on the face. Facial cleansing wipes may be an underrecognized source of allergens. OBJECTIVE: The aim of this study was to determine the frequency of potentially allergenic ingredients in facial wet wipes. METHODS: Ingredient lists from name brand and generic facial wipes from 4 large retailers were analyzed. RESULTS: In the 178 facial wipes examined, a total of 485 ingredients were identified (average, 16...
March 23, 2017: Dermatitis
https://www.readbyqxmd.com/read/28338537/allergenic-ingredients-in-personal-hygiene-wet-wipes
#7
Kelly A Aschenbeck, Erin M Warshaw
BACKGROUND: Wet wipes are a significant allergen source for anogenital allergic contact dermatitis. OBJECTIVE: The aim of the study was to calculate the frequency of potentially allergenic ingredients in personal hygiene wet wipes. METHODS: Ingredient lists from brand name and generic personal hygiene wet wipes from 4 large retailers were compiled. RESULTS: In the 54 personal hygiene wet wipes evaluated, a total of 132 ingredients were identified (average of 11...
March 23, 2017: Dermatitis
https://www.readbyqxmd.com/read/28331897/erosive-pustular-dermatosis-of-the-scalp-after-contact-dermatitis-from-a-prosthetic-hair-piece
#8
Jay S Herbst, Alexander T Herbst
No abstract text is available yet for this article.
March 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28329482/prevention-of-poison-ivy-dermatitis-with-oral-homeopathic-rhus-toxicodendron
#9
Robert Joseph Signore
Acute allergic contact dermatitis to poison ivy is acommon and miserable dermatosis which affectsmillions of Americans each year. Preventativemeasures, such as avoidance, protective clothing,barrier creams, soaps, and solvents often fail despiteour patients' best attempts. Severe allergic reactionsto poison ivy are a significant source of decreasedemployee productivity owing to inability to work anda major health care expenditure. Patients may haveto leave their jobs and discontinue favorite outdoorrecreational activities as a result of severe urushiolsensitivity...
January 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329062/comparison-of-demographic-and-photobiological-features-of-chronic-actinic-dermatitis-in-patients-with-lighter-vs-darker-skin-types
#10
Ki-Wei Tan, Ann K Haylett, Tsui C Ling, Lesley E Rhodes
Importance: Chronic actinic dermatitis (CAD) is classically described in older, white men, although increasing reports describe younger patients with darker skin types, particularly South Asians. Photocontact allergy occurs in CAD but is less studied than contact allergy in this exquisitely photosensitive condition. Objective: To evaluate for differences in demographic and photobiological features between persons with darker and lighter skin types who have CAD. Design, Setting, and Participants: This retrospective review included 70 consecutive adult patients (≥18 years) undergoing investigation for photosensitivity who were diagnosed with CAD from November 1, 2000, through August 31, 2015, at the specialist Photobiology Unit of a tertiary academic referral center...
March 22, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28328819/prevalence-and-risk-factors-of-contact-dermatitis-among-clothing-manufacturing-employees-in-beijing-a-cross-sectional-study
#11
Yu-Xin Chen, Hai-Yan Cheng, Lin-Feng Li
Little is known about the epidemiology of contact dermatitis (CD) in the Chinese clothing industry. This study aimed to investigate the prevalence and some risk factors of contact dermatitis among clothing manufacturing employees in Beijing.This cross-sectional study was conducted by interview using self-administered questionnaires and skin examination between May and August in 2016. Five-hundred twenty-nine employees who had worked at sewing, ironing, and as managers at 12 clothing manufacturing factories were studied...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28326907/skin-sensitizers-in-cosmetics-and-beyond-potential-multiple-mechanisms-of-action-and-importance-of-t-cell-assays-for-in-vitro-screening
#12
Stanislav Vukmanović, Nakissa Sadrieh
Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity (DTH) reaction induced by repeated contact with sensitizers. The ability of a chemical to act as a sensitizer has most frequently been tested in animals. As the use of animals for these purposes is gradually and globally being phased out, there is a need for reliable in vitro surrogate assays. Currently proposed in vitro assays are designed to test four key events of the adverse outcome pathway (AOP) involving covalent modification of self-proteins by sensitizers (haptenation) and presentation of new antigens (hapten/carrier complexes) to the immune system...
March 22, 2017: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/28320580/roles-of-alternatively-activated-m2-macrophages-in-allergic-contact-dermatitis
#13
REVIEW
Kotaro Suzuki, Kazuyuki Meguro, Daiki Nakagomi, Hiroshi Nakajima
Alternatively activated macrophages (M2 macrophages) play key roles in the suppression of Th1 cell responses and the orchestration of tissue repair. However, recent studies have shown that M2 macrophages have potentials to produce high levels of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α, suggesting that M2 macrophages may exacerbate inflammation in some settings. In this regard, we have recently shown that large numbers of M2 macrophages accumulate in the sites of hapten-induced contact hypersensitivity (CHS), an animal model of allergic contact dermatitis, and that M2 macrophages exacerbate hapten-induced CHS by producing matrix metalloproteinase 12 (MMP12)...
March 17, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28318051/atopic-dermatitis-in-israeli-adolescents-from-1998-to-2013-trends-in-time-and-association-with-migraine
#14
Rony Shreberk-Hassidim, Ayal Hassidim, Yoav Gronovich, Adam Dalal, Vered Molho-Pessach, Abraham Zlotogorski
BACKGROUND: Recent data have shown an increasing occurrence of atopic dermatitis (AD) in children and adolescents, as well as in adults. Most of the epidemiologic research on AD is limited to pediatric and youth populations and is based on self-reported questionnaires. METHODS: A nationwide, population-based, cross-sectional retrospective study of adolescents with AD was performed to estimate its prevalence, trends, and association with demographic factors and comorbidities...
March 20, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28317196/severe-bullous-allergic-contact-dermatitis-caused-by-diethylthiourea-20-years-after-sensitization-to-neoprene
#15
Anne Bregnhøj, Mette Sommerlund
No abstract text is available yet for this article.
April 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28317191/allergic-contact-dermatitis-caused-by-motorcycle-heated-grips
#16
Nicola Milanesi, Massimo Gola, Stefano Francalanci
No abstract text is available yet for this article.
April 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28317188/occupational-opiate-contact-dermatitis
#17
Sophie Colomb, Jean L Bourrain, Nathalie Bonardel, Anca Chiriac, Pascal Demoly
No abstract text is available yet for this article.
April 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28317187/occupational-allergic-contact-dermatitis-caused-by-1-propanol-in-a-hand-disinfectant
#18
Hilde M Bosker, Klaziena Politiek, Merel C Urgert, Peter A Flach, Pieter-Jan Coenraads, Marie Louise Schuttelaar
No abstract text is available yet for this article.
April 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28317186/intolerance-to-cosmetics-as-key-to-the-diagnosis-in-a-patient-with-allergic-contact-dermatitis-caused-by-propylene-glycol-contained-in-a-topical-medication
#19
Noelia Hernández, Zaida Hernández, Federica Liuti, Leopoldo Borrego
No abstract text is available yet for this article.
April 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28300444/methylisothiazolinone-contact-allergy-prevalence-in-western-canada
#20
Jessica E Wilford, Gillian C de Gannes
BACKGROUND: Contact allergy to methylisothiazolinone (MI) or to the combination of methylchloroisothiazolinone and MI (MCI/MI) is an important and increasing cause of allergic contact dermatitis, with prevalence rates higher than 10% in some centers. OBJECTIVES: The objective of this retrospective chart review is to provide a western Canadian perspective on whether the positive patch testing rate to MCI/MI or MI increased during the testing period of 2008 to 2015 and whether the addition of MI at 2000 ppm resulted in increased detection...
January 1, 2017: Journal of Cutaneous Medicine and Surgery
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