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https://www.readbyqxmd.com/read/28674847/a-new-integrated-dual-time-point-amyloid-pet-mri-data-analysis-method
#1
Diego Cecchin, Henryk Barthel, Davide Poggiali, Annachiara Cagnin, Solveig Tiepolt, Pietro Zucchetta, Paolo Turco, Paolo Gallo, Anna Chiara Frigo, Osama Sabri, Franco Bui
PURPOSE: In the initial evaluation of patients with suspected dementia and Alzheimer's disease, there is no consensus on how to perform semiquantification of amyloid in such a way that it: (1) facilitates visual qualitative interpretation, (2) takes the kinetic behaviour of the tracer into consideration particularly with regard to at least partially correcting for blood flow dependence, (3) analyses the amyloid load based on accurate parcellation of cortical and subcortical areas, (4) includes partial volume effect correction (PVEC), (5) includes MRI-derived topographical indexes, (6) enables application to PET/MRI images and PET/CT images with separately acquired MR images, and (7) allows automation...
July 4, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28661018/clinical-characterization-of-dystonia-in-adult-patients-with-huntington-s-disease
#2
N A van de Zande, T H Massey, D McLauchlan, A Pryce Roberts, R Zutt, M Wardle, G C Payne, C Clenaghan, M A J Tijssen, A E Rosser, K J Peall
BACKGROUND AND PURPOSE: Huntington's disease (HD) is an autosomal dominant, neurodegenerative movement disorder, typically characterized by chorea. Dystonia is also recognized as part of the HD motor phenotype, although little work detailing its prevalence, distribution, severity and impact on functional capacity has been published to date. METHODS: Patients (>18 years of age) were recruited from the Cardiff (UK) HD clinic, each undergoing a standardized videotaped clinical examination and series of functional assessment questionnaires (Unified Huntington's Disease Rating Scale, Burke-Fahn-Marsden Dystonia Rating Scale and modified version of the Toronto Western Spasmodic Torticollis Rating Scale)...
June 29, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28619653/on-optimal-spatial-filtering-for-the-detection-of-phase-coupling-in-multivariate-neural-recordings
#3
G Waterstraat, G Curio, V V Nikulin
INTRODUCTION: Neuronal oscillations synchronize processing in the brain over large spatiotemporal scales and thereby facilitate integration of individual functional modules. Up to now, the relation between the phases of neuronal oscillations and behavior or perception has mainly been analyzed in sensor space of multivariate EEG/MEG recordings. However, sensor-space analysis distorts the topographies of the underlying neuronal sources and suffers from low signal-to-noise ratio. Instead, we propose an optimized source reconstruction approach (Phase Coupling Optimization, PCO)...
June 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28511128/improving-the-repeatability-of-motor-unit-number-index-munix-by-introducing-additional-epochs-at-low-contraction-levels
#4
Yun Peng, Yingchun Zhang
OBJECTIVE: To evaluate the repeatability of (Motor Unit Number Index) MUNIX under repeatability conditions, specify the origin of variations and provide strategies for quality control. METHODS: MUNIX calculations were performed on the bicep brachii muscles of eight healthy subjects. Negative effect of suboptimal electrode positions on MUNIX accuracy was eliminated by employing the high-density surface electromyography technique. MUNIX procedures that utilized a variety of surface interferential pattern (SIP) epoch recruitment strategies (including the original MUNIX procedure, two proposed improvement strategies and their combinations) were described...
July 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28481192/assessing-postural-balance-in-early-parkinson-s-disease-validity-of-the-bdl-balance-scale
#5
Ingrid M Claesson, Wilhelmus Ja Grooten, Johan Lökk, Agneta Ståhle
BACKGROUND: There is a need for a valid assessment test of balance in early Parkinson's disease (PD). OBJECTIVE: To validate the Bäckstrand Dahlberg Liljenäs Balance Scale (BDL), a test of balance performance constructed to assess mild to moderate balance disability due to neurological disease, for use in persons with early PD. METHODS: Cross-sectional psychometric evaluation study from a convenience sample community-dwelling persons with PD (n = 28)...
May 8, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28461068/coil-optimisation-for-transcranial-magnetic-stimulation-in-realistic-head-geometry
#6
Lari M Koponen, Jaakko O Nieminen, Tuomas P Mutanen, Matti Stenroos, Risto J Ilmoniemi
BACKGROUND: Transcranial magnetic stimulation (TMS) allows focal, non-invasive stimulation of the cortex. A TMS pulse is inherently weakly coupled to the cortex; thus, magnetic stimulation requires both high current and high voltage to reach sufficient intensity. These requirements limit, for example, the maximum repetition rate and the maximum number of consecutive pulses with the same coil due to the rise of its temperature. OBJECTIVE: To develop methods to optimise, design, and manufacture energy-efficient TMS coils in realistic head geometry with an arbitrary overall coil shape...
July 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28359713/child-passenger-safety-an-assessment-of-emergency-nurses-knowledge-and-provision-of-information-in-the-emergency-department
#7
Thelma C Kuska, Mark R Zonfrillo
Each year, more than 130,000 children younger than 13 years are treated in the emergency department after evaluation of injuries sustained from motor vehicle crashes (MVCs). Many of these injuries can be prevented with use of child restraints. In this study we sought to assess emergency nurses' knowledge of child passenger safety (CPS) and its use to keep children safe while traveling in motor vehicles. METHODS: A cross-sectional anonymous study was distributed electronically to 530 emergency nurses who were asked to forward the survey link to other emergency nurses through snowball sampling...
March 28, 2017: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://www.readbyqxmd.com/read/28276586/the-eating-and-drinking-ability-classification-system-in-a-population-based-sample-of-preschool-children-with-cerebral-palsy
#8
Katherine A Benfer, Kelly A Weir, Kristie L Bell, Robert S Ware, Peter S W Davies, Roslyn N Boyd
AIM: To determine (1) the reproducibility of the Eating and Drinking Ability Classification System (EDACS); (2) EDACS classification distribution in a population-based cohort with cerebral palsy (CP); and (3) the relationships between the EDACS and clinical mealtime assessment, other classifications, and health outcomes. METHOD: This was a cross-sectional population-based cohort study of 170 children with CP at 3 years to 5 years (mean 57.6mo, standard deviation [SD] 8...
June 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28177571/optimizing-for-generalization-in-the-decoding-of-internally-generated-activity-in-the-hippocampus
#9
Matthijs A A van der Meer, Alyssa A Carey, Youki Tanaka
The decoding of a sensory or motor variable from neural activity benefits from a known ground truth against which decoding performance can be compared. In contrast, the decoding of covert, cognitive neural activity, such as occurs in memory recall or planning, typically cannot be compared to a known ground truth. As a result, it is unclear how decoders of such internally generated activity should be configured in practice. We suggest that if the true code for covert activity is unknown, decoders should be optimized for generalization performance using cross-validation...
May 2017: Hippocampus
https://www.readbyqxmd.com/read/28100095/shoulder-kinetics-during-start-up-and-propulsion-with-a-manual-wheelchair-within-the-initial-phase-of-uninstructed-training
#10
Samuel Hybois, Alice Siegel, Joseph Bascou, Nicolas Eydieux, Philippe Vaslin, Hélène Pillet, Pascale Fodé, Christophe Sauret
PURPOSE: Wheelchair locomotion is constraining for the upper limbs and involves a set of motor tasks that need to be learnt by a novice user. To understand this integration process, we investigated the evolution of shoulder kinetics during start-up and propulsion within the initial phase of low-intensity uninstructed training. MATERIALS AND METHODS: Seventeen novice able-bodied subjects performed a 120-min uninstructed practice distributed over 4 weeks. During the initial and final sessions, upper limbs kinematics and hand-rim kinetics were continuously collected...
January 19, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28048257/th-c-brb-01-open-source-hardware-general-overview
#11
F Therriault-Proulx
By definition, Open Source Hardware (OSH) is "hardware whose design is made publicly available so that anyone can study, modify, distribute, make, and sell the design or hardware based on that design". The advantages of OSH are multiple and the movement has been growing exponentially over the last couple years, leading to the spread and evolution of 3D printing technologies, the creation of affordable and easy to use micro-controller boards (Arduino, Raspberry Pi, etc.), as well as a plurality of other "hands-on"/DIY projects...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047610/th-c-brb-02-open-source-medical-devices-lessons-learned-from-a-complex-collaborative-research-project
#12
S Prajapati
By definition, Open Source Hardware (OSH) is "hardware whose design is made publicly available so that anyone can study, modify, distribute, make, and sell the design or hardware based on that design". The advantages of OSH are multiple and the movement has been growing exponentially over the last couple years, leading to the spread and evolution of 3D printing technologies, the creation of affordable and easy to use micro-controller boards (Arduino, Raspberry Pi, etc.), as well as a plurality of other "hands-on"/DIY projects...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047153/th-c-brb-00-open-source-hardware-in-medical-physics-and-its-potential-to-accelerate-innovation
#13
Francois Therriault-Proulx
By definition, Open Source Hardware (OSH) is "hardware whose design is made publicly available so that anyone can study, modify, distribute, make, and sell the design or hardware based on that design". The advantages of OSH are multiple and the movement has been growing exponentially over the last couple years, leading to the spread and evolution of 3D printing technologies, the creation of affordable and easy to use micro-controller boards (Arduino, Raspberry Pi, etc.), as well as a plurality of other "hands-on"/DIY projects...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046962/th-c-brb-03-open-source-hardware-in-the-context-of-simple-and-widely-shared-clinical-applications
#14
J Cunha
By definition, Open Source Hardware (OSH) is "hardware whose design is made publicly available so that anyone can study, modify, distribute, make, and sell the design or hardware based on that design". The advantages of OSH are multiple and the movement has been growing exponentially over the last couple years, leading to the spread and evolution of 3D printing technologies, the creation of affordable and easy to use micro-controller boards (Arduino, Raspberry Pi, etc.), as well as a plurality of other "hands-on"/DIY projects...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27920096/structural-pathways-supporting-swift-acquisition-of-new-visuomotor-skills
#15
Ari E Kahn, Marcelo G Mattar, Jean M Vettel, Nicholas F Wymbs, Scott T Grafton, Danielle S Bassett
Human skill learning requires fine-scale coordination of distributed networks of brain regions linked by white matter tracts to allow for effective information transmission. Yet how individual differences in these anatomical pathways may impact individual differences in learning remains far from understood. Here, we test the hypothesis that individual differences in structural organization of networks supporting task performance predict individual differences in the rate at which humans learn a visuomotor skill...
January 1, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/27771201/validation-of-the-tablet-administered-brief-assessment-of-cognition-bac-app
#16
Alexandra S Atkins, Tina Tseng, Adam Vaughan, Elizabeth W Twamley, Philip Harvey, Thomas Patterson, Meera Narasimhan, Richard S E Keefe
Computerized tests benefit from automated scoring procedures and standardized administration instructions. These methods can reduce the potential for rater error. However, especially in patients with severe mental illnesses, the equivalency of traditional and tablet-based tests cannot be assumed. The Brief Assessment of Cognition in Schizophrenia (BACS) is a pen-and-paper cognitive assessment tool that has been used in hundreds of research studies and clinical trials, and has normative data available for generating age- and gender-corrected standardized scores...
October 19, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27662531/effects-of-transcranial-stimulating-electrode-montages-over-the-head-for-lower-extremity-transcranial-motor-evoked-potential-monitoring
#17
Ryosuke Tomio, Takenori Akiyama, Takayuki Ohira, Kazunari Yoshida
OBJECTIVE The aim of this study was to determine the most effective electrode montage to elicit lower-extremity transcranial motor evoked potentials (LE-tMEPs) using a minimum stimulation current. METHODS A realistic 3D head model was created from T1-weighted images. Finite element methods were used to visualize the electric field in the brain, which was generated by transcranial electrical stimulation via 4 electrode montage models. The stimulation threshold level of LE-tMEPs in 52 patients was also studied in a practical clinical setting to determine the effects of each electrode montage...
June 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27580298/analysis-of-hand-and-wrist-postural-synergies-in-tolerance-grasping-of-various-objects
#18
Yuan Liu, Li Jiang, Dapeng Yang, Hong Liu
Human can successfully grasp various objects in different acceptable relative positions between human hand and objects. This grasp functionality can be described as the grasp tolerance of human hand, which is a significant functionality of human grasp. To understand the motor control of human hand completely, an analysis of hand and wrist postural synergies in tolerance grasping of various objects is needed. Ten healthy right-handed subjects were asked to perform the tolerance grasping with right hand using 6 objects of different shapes, sizes and relative positions between human hand and objects...
2016: PloS One
https://www.readbyqxmd.com/read/27575536/the-history-and-characteristics-of-the-mobulid-ray-fishery-in-the-bohol-sea-philippines
#19
Jo Marie V Acebes, Malcolm Tull
The fishery for mobulid rays, also known as devil rays, has been practiced in the Bohol Sea for over a century yet very little is known about its history and characteristics. This study provides the first detailed description of the mobulid ray fishery in the Bohol Sea, Philippines. It describes the history and evolution of the fishery from the 19th century to 2013. It characterizes the fishery based on the species targeted, gears used, the organization, catch distribution, processing, monetary value, and the market of its by-products...
2016: PloS One
https://www.readbyqxmd.com/read/27406858/dietary-habits-and-neurological-features-of-parkinson-s-disease-patients-implications-for-practice
#20
Michela Barichella, Emanuele Cereda, Erica Cassani, Giovanna Pinelli, Laura Iorio, Valentina Ferri, Giulia Privitera, Marianna Pasqua, Angela Valentino, Fatemeh Monajemi, Serena Caronni, Caterina Lignola, Chiara Pusani, Carlotta Bolliri, Samanta A Faierman, Alessandro Lubisco, Giuseppe Frazzitta, Maria L Petroni, Gianni Pezzoli
BACKGROUND & AIMS: Parkinson's disease (PD) patients can benefit considerably from appropriate nutritional care, particularly from diet. However, there is limited evidence on the eating habits of PD patients and their relationship with the features of the disease. METHODS: We conducted a large case-control study. Consecutive PD patients (N = 600) receiving systematic nutritional care and healthy controls (N = 600) matched (1:1) for age, gender, education, physical activity level and residence were studied using a 66-item food frequency questionnaire...
July 5, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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