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https://www.readbyqxmd.com/read/29223934/-hypoglycaemia-in-patients-with-type-1-and-type-2-diabetes-mellitus-on-insulin-therapy-results-of-the-global-hat-study-in-argentina
#1
José E Costa Gil, María A Linari, Natalia Pugnaloni, Fabio G Zambon, Federico Pérez Manghi, Mariana Rezzónico
We describe the results of the HAT study in 433 Argentinean patients with type 1 diabetes (T1D) and 823 with type 2 diabetes (T2D). HAT was an international non-interventional study assessing severe and non-severe hypoglycaemia in patients with T1D and T2D under insulin treatment through a two-part self-assessment questionnaire (retrospective and prospective). The annual incidence of at least one hypoglycaemic episode was 46 episode/patient/year in T1D and 14.2 in T2D (retrospective), 96.5 and 24.6 episode/patient/year in T1D and T2D, respectively (prospective)...
2017: Medicina
https://www.readbyqxmd.com/read/29221827/prevalence-of-copd-in-6-urban-clusters-in-argentina-the-epoc-ar-study
#2
Andrés L Echazarreta, Sergio J Arias, Ricardo Del Olmo, Eduardo R Giugno, Federico D Colodenco, Santiago C Arce, Juan C Bossio, Gustavo Armando, Joan B Soriano
INTRODUCTION: The prevalence of chronic obstructive pulmonary disease (COPD) has not been studied in Argentina. OBJECTIVES: To determine the prevalence and relevant clinical characteristics of COPD in a representative sample. MATERIAL AND METHODS: We performed a cross-sectional study in a population of adults aged ≥ 40 years randomly selected by cluster sampling in 6 urban locations. Subjects answered a structured survey and performed pre- and post-bronchodilator spirometry (PBD)...
December 5, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/29180276/dalbavancin-in-the-treatment-of-different-gram-positive-infections-a-real-life-experience
#3
Emilio Bouza, Maricela Valerio, Alex Soriano, Laura Morata, Enrique García Carus, Carmen Rodríguez-González, Ma Carmen Hidalgo-Tenorio, Antonio Plata, Patricia Muñoz, Antonio Vena
Dalbavancin is a lipoglycopeptide with a very prolonged half-life that enables treatments with a single IV administration that has been approved to treat complicated skin and soft tissue infections. Information on the efficacy and safety of Dalbavancin in other situations is very scarce. This retrospective study includes adult patients who received at least one dose of Dalbavancin between 2016 and 2017 in 29 institutions in Spain. Primary objective was to report the use of Dalbavancin in clinical practice including its efficacy and tolerability...
November 24, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29174522/-differences-in-the-management-of-patients-with-atrial-fibrillation-according-to-whether-primary-care-or-the-specialist-initiates-treatment-with-direct-oral-anticoagulants-the-silver-ap-and-bronce-ap-studies
#4
M de la Figuera, M A Prieto, N Marín, I Egocheaga, S Cinza
OBJECTIVES: To determine the clinical characteristics and management of patients with non-valvular atrial fibrillation (NVAF) treated with direct oral anticoagulants (DOAC) according to who initiates their prescription, the Primary Care (PC) physician or referring the patient to a specialist. MATERIAL AND METHODS: Two observational, cross-sectional and multicentre studies were compared for this purpose. The SILVER-AP study was performed in those autonomous communities in which the PC physician can prescribe DOAC directly, and the BRONCE-AP study in those autonomous communities in which the PC physician has to refer the patient to the specialist to start treatment with DOAC...
November 23, 2017: Semergen
https://www.readbyqxmd.com/read/29171615/data-sharing-statements-for-clinical-trials-a-requirement-of-the-international-committee-of-medical-journal-editors
#5
Darren B Taichman, Peush Sahni, Anja Pinborg, Larry Peiperl, Christine Laine, Astrid James, Sung-Tae Hong, Abraham Haileamlak, Laragh Gollogly, Fiona Godlee, Franka Frizelle, Fernando Florenzano, Jeffrey M Drazen, Howard Bauchner, Christopher Baethge, Joyce Backus
El Comité Internacional de Editores de Revista Médicas (ICMJE) ha tomado la posición que el compartir los datos generados por los ensayos clínicos es una obligación ética, por cuanto los participantes en esos estudios se colocaron en riesgo al aceptar su inclusión. En esta editorial el ICMJE expresa que requerirá desde Julio 2018 que los manuscritos enviados a sus revistas deben incluir una declaración sobre compartir datos. A su vez, los ensayos clínicos que comiencen a enrolar pacientes a partir de Enero 2019, deben incluir un plan sobre compartir datos en el registro de tales ensayos...
June 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29165933/transmission-scenarios-of-major-vector-borne-diseases-in-colombia-1990-2016
#6
Julio César Padilla, Fredy Eberto Lizarazo, Olga Lucía Murillo, Fernando Antonio Mendigaña, Edwin Pachón, Mauricio Javier Vera
Introducción. Las enfermedades transmitidas por vectores representan más de 17 % de todas las enfermedades infecciosas y causan anualmente un millón de defunciones a nivel mundial. En Colombia, la malaria, el dengue, la enfermedad de Chagas y las leishmaniasis son condiciones endemoepidémicas persistentes.Objetivo. Determinar el comportamiento epidemiológico de las enfermedades transmitidas por vectores en zonas urbanas y rurales de Colombia entre 1990 y 2016.Materiales y métodos. Se hizo un estudio descriptivo del comportamiento epidemiológico de las principales enfermedades transmitidas por vectores en zonas urbanas y rurales de Colombia entre 1990 y 2016, con la información proveniente de fuentes oficiales secundarias...
March 29, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29136613/increasing-incidence-and-prevalence-of-multiple-sclerosis-in-puerto-rico-2013-2016
#7
Angel Chinea, Carlos F Ríos-Bedoya, Ivonne Vicente, Cristina Rubí, Guillermo García, Ana Rivera, Astrid Díaz, Eduardo Estades Romero, Yatzka Hernández Silvestrini, Yaritza Díaz
BACKGROUND: The incidence of multiple sclerosis (MS) has been increasing worldwide over the past decades. However, this upward trend has not been examined at the country level in Latin America and the Caribbean (LAC). The aims of this study are to examine trends of MS incidence over 4 years and to provide age- and gender-standardized incidence rate estimates for a Caribbean island. METHODS: Data from the Puerto Rico (PR) MS Foundation's registry was used to identify all newly diagnosed MS cases between 2013 and 2016...
November 14, 2017: Neuroepidemiology
https://www.readbyqxmd.com/read/29129386/atrial-fibrillation-in-patients-on-haemodialysis-in-andalusia-prevalence-clinical-profile-and-therapeutic-management
#8
Carmen Sánchez Perales, Teresa Vázquez Sánchez, Daniel Salas Bravo, Sonia Ortega Anguiano, Eduardo Vázquez Ruiz de Castroviejo
Atrial fibrillation (AF) represents an important social and healthcare problem. There is wide variability in the prevalence of this arrhythmia in studies analysing patients on haemodialysis (HD). OBJECTIVE: To investigate the prevalence, clinical profile and therapeutic management of patients with AF on HD in Andalusia. METHODS: We asked the public healthcare system of Andalusia to provide us with the number of patients who were being treated with HD. We asked attending nephrologists from all hospital and outpatient centres in 5 of the 8 Andalusian provinces to perform an electrocardiogram and to fill out a questionnaire on patients selected by simple random sampling...
November 9, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29125387/significado-de-psic%C3%A3-logas-os-de-atenci%C3%A3-n-primaria-de-salud-sobre-la-intervenci%C3%A3-n-psicosocial-de-grupo-en-el-tratamiento-de-la-depresi%C3%A3-n-en-chile
#9
Gonzalo Andrade, Adriana Espinoza
En Chile, el tratamiento de la depresión en salud pública promueve la realización de Intervenciones Psicosociales en Grupo (IPG) para todos los casos diagnosticados, no obstante, se observa una baja implementación de estas prestaciones. El presente artículo describe y caracteriza, desde el punto de vista de la disciplina psicológica, el significado de psicólogas/os que trabajan en consultorios de atención primaria de salud (APS) sobre las IPG en el tratamiento de la depresión. Se entrevistaron a ocho psicólogas/os de los distintos Servicios de Salud de la Región Metropolitana de Santiago...
November 1, 2017: Global Health Promotion
https://www.readbyqxmd.com/read/29099829/tratamiento-con-fosfato-de-sitagliptina-en-pacientes-con-hipoglucemia-reactiva-secundaria-a-disinsulinismo-estudio-controlado-aleatorizado-y-doble-ciego
#10
Daniel Cuevas-Ramos, Paloma Almeda-Valdés, Clara E Meza-Arana, Griselda Brito-Córdova, Doris Georgina Ruiz-Gómez, Christian Razo, Francisco J Gómez-Pérez
Objective: We evaluated the effect of sitagliptin in correction of symptomatic reactive hypoglycemia. Methods: Randomized, double blind, placebo-controlled clinical trial. Thirteen patients treated with sitagliptin and 15 with placebo, with mean age of 34.3 ± 10.6 years and body mass index of 24.6 ± 5.1 kg/m(2), mostly women (n = 24, 85.7%), were evaluated. Results: Basal glycemia was similar in placebo versus sitagliptin (92.3 ± 18.9 vs...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/29099119/el-an%C3%A3-lisis-molecular-de-la-secuencia-del-genoma-completo-de-aislados-cl%C3%A3-nicos-de-vibrio-cholerae-en-m%C3%A3-xico-en-2013-revela-la-presencia-de-la-cepa-causante-de-la-epidemia-de-hait%C3%A3-en-2010
#11
José Alberto Díaz-Quiñonez
La primera semana de septiembre de 2013, el Sistema Nacional de Vigilancia Epidemiológica identificó dos casos de cólera en Ciudad de México. Los cultivos de ambas muestras se confirmaron como Vibrio cholerae serogrupo O1, serotipo Ogawa, biotipo El Tor. Los análisis iniciales por electroforesis por campos pulsados y por reacción en cadena de la polimerasa indicaron que ambas cepas eran similares, pero diferentes de las previamente reportadas en México. La semana siguiente se identificaron cuatro casos más en una comunidad del Estado de Hidalgo, ubicada a 121 kilómetros al noreste de Ciudad de México...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/29099100/deficiencia-de-vitamina-d-y-su-asociaci%C3%A3-n-con-enfermedad-arterial-coronaria-en-poblaci%C3%A3-n-mexicana-estudio-gen%C3%A3-tico-de-la-enfermedad-aterosclerosa
#12
Fabiola López-Bautista, Carlos Posadas-Romero, Guillermo Cardoso-Saldaña, Juan Gabriel Juárez-Rojas, Aida Medina-Urrutia, Nonanzit Pérez-Hernández, José Manuel Rodríguez-Pérez, Gilberto Vargas-Alarcón, Rosalinda Posadas-Sánchez
Objective: To investigate the independent association between vitamin D deficiency (VDD) and coronary artery disease (CAD) in Mexican adult population. Method: Matched case-control study. Data cardiovascular on risk factors, medication use, physical activity, alcohol use, smoking and vitamin D consumption were obtained. Biochemical variables, anthropometric and blood pressure were measured. 25(OH)D was quantified by chemiluminescence. Results: We studied 250 patients with established CAD and 250 age-gender-body mass index (BMI) matched control subjects, with a mean age of 53 ± 6...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/29054460/-what-is-the-european-code-against-cancer-who-knows-it-and-why-it-serves
#13
Luis Angel Pérula de Torres, Carolina Espina García
No abstract text is available yet for this article.
October 18, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/29023261/prevention-of-ventilator-associated-pneumonia-the-multimodal-approach-of-the-spanish-icu-pneumonia-zero-program
#14
Francisco Álvarez-Lerma, Mercedes Palomar-Martínez, Miguel Sánchez-García, Montserrat Martínez-Alonso, Joaquín Álvarez-Rodríguez, Leonardo Lorente, Susana Arias-Rivera, Rosa García, Federico Gordo, José M Añón, Rosa Jam-Gatell, Mónica Vázquez-Calatayud, Yolanda Agra
OBJECTIVES: The "Pneumonia Zero" project is a nationwide multimodal intervention based on the simultaneous implementation of a comprehensive evidence-based bundle measures to prevent ventilator-associated pneumonia in critically ill patients admitted to the ICU. DESIGN: Prospective, interventional, and multicenter study. SETTING: A total of 181 ICUs throughout Spain. PATIENTS: All patients admitted for more than 24 hours to the participating ICUs between April 1, 2011, and December 31, 2012...
October 11, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28992980/adherence-to-recommendations-of-the-therapeutic-positioning-report-about-treatment-with-oral-anticoagulants-in-elderly-patients-with-atrial-fibrillation-the-esparta-study
#15
Carmen Suárez Fernández, Jose María Mostaza, Luis Castilla Guerra, Jesus Cantero Hinojosa, Josep Maria Suriñach, Fernando Acosta de Bilbao, Juan José Tamarit, José Luis Diaz Diaz, Jose Luis Hernandez, Daniel Cazorla, Carles Ràfols
BACKGROUND AND OBJECTIVE: To evaluate the adherence to the recommendations in clinical practice performed by the Therapeutic Positioning Report (TPR) of the Spanish Agency of Medicines and Sanitary Products about the treatment with oral anticoagulants in patients aged≥75 years old with nonvalvular atrial fibrillation (NVAF) treated in Internal Medicine departments in Spain. PATIENTS AND METHODS: Observational, cross-sectional and multicenter study in which 837 patients aged≥75 years old with NVAF, with stable treatment with oral anticoagulants at least 3 months before inclusion, and that had started treatment with oral anticoagulants before the inclusion period were included...
October 6, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28991289/physical-activity-and-its-association-with-chronic-diseases-in-the-elderly-in-11-cities-of-peru
#16
Christian R Mejia, Araseli Verastegui-Díaz, Dante M Quiñones-Laveriano, Germán Aranzabal-Alegría, Virgilio E Failoc-Rojas
Aim: To determine the frequency of physical activity and its association with chronic diseases in the elderly in eleven cities of Peru. Methods: A cross-sectional study of secondary data was conducted; the dependent variable was not the realization of physical activity, chronic disease and other physio-anthropometric variables were independent variables. For bivariate and multivariate analysis generalized linear models were used. A confidence level of 95% and p < 0...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28991282/knowledge-and-attitude-towards-organ-donation-of-medicine-students-of-a-northwestern-mexico-public-university
#17
María José Sebastián-Ruiz, Elda Karina Guerra-Sáenz, Anna Karen Vargas-Yamanaka, Oralia Barboza-Quintana, Antonio Ríos-Zambudio, Ricardo García-Cabello, Gerardo Del Carmen Palacios-Saucedo
Introduction: The issue of organ donation is scarcely addressed during undergraduate medical studies. Objective: To evaluate the knowledge and attitude towards organ donation of medicine students of a Northwestern Mexico public university. Materials and Methods: A prolective, descriptive, observational, and cross-sectional study. A 34 items cross-sectional survey evaluating knowledge and attitude towards organ donation in 3056 medicine students during 2013-2015...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28991281/splanchnic-vein-thrombosis-as-a-first-manifestation-of-primary-myelofibrosis
#18
Gregorio Campos-Cabrera, Virginia Campos-Cabrera, Salvador Campos-Cabrera, José-Luis Campos-Villagómez, Alejandra Romero-González
Myeloproliferative neoplasms are chronic disorders of clonal hematopoietic stem cells, characterized by an overproduction of functional granulocytes, red blood cells and / or platelets, and one of the major complications is the occurrence of venous and arterial thrombotic problems caused by increased platelet aggregation and thrombin generation. In this study 11 cases of primary myelofibrosis (PM) were evaluated and 2 debuted with splanchnic venous thrombosis (SVT); so after seeing the results of this study and of world literature, it is suggested that in patients with SVT, diagnostic methods for PM like the JAK2V617F mutation should be included...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28991280/platelet-rich-plasma-and-its-effect-in-bone-regeneration-in-mandibular-fractures-controlled-clinical-trial
#19
Guadalupe Castillo-Cardiel, Víctor Manuel Medina-Quintana, Mario Lomelí-Enríquez, Fabiola Medrano-Muñoz, Celia Guerrero-Velázquez, Carmen Karina Contreras-López, Clotilde Fuentes-Orozco, Leire Irusteta-Jiménez, Luis Rodrigo Michel-Espinoza, Alejandro González-Ojeda
Background: Currently there is great interest in developing clinical applications of platelet-rich plasma to enhance bone repair. Aim: To assess bone regeneration in mandibular fractures, with the application of this adjuvant. Methods: Twenty patients with mandibular fractures were included in a randomized clinical trial. Patients of the experimental group (n = 10) were submitted to internal fracture reduction and administration of platelet-rich plasma, and patients of the control group (n = 10) were submitted to the same surgical procedure without plasma application...
2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28991279/the-role-of-gamma-aminobutyric-acid-in-female-depression
#20
Mónica Flores-Ramos, Margus Salinas, Armando Carvajal-Lohr, Lorena Rodríguez-Bores
Depression is a common psychiatric disorder and a leading cause of disability worldwide. Multiple and diverse factors are involved in its cause although biologic factors are prominent. The present study reviews the evidence about the role that gamma-aminobutyric acid plays in the complex pathogenesis of depression, particularly in women. The implication of gamma-aminobutyric acid (GABA) is based mainly from animal models whereas clinical studies in depressed patients show alterations of GABA levels in plasma and cerebrospinal fluid...
2017: Gaceta Médica de México
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