keyword
MENU ▼
Read by QxMD icon Read
search

Translational science

keyword
https://www.readbyqxmd.com/read/29346376/evaluating-the-sustainability-scalability-and-replicability-of-an-sth-transmission-interruption-intervention-the-deworm3-implementation-science-protocol
#1
Arianna Rubin Means, Sitara S R Ajjampur, Robin Bailey, Katya Galactionova, Marie-Claire Gwayi-Chore, Katherine Halliday, Moudachirou Ibikounle, Sanjay Juvekar, Khumbo Kalua, Gagandeep Kang, Pallavi Lele, Adrian J F Luty, Rachel Pullan, Rajiv Sarkar, Fabian Schär, Fabrizio Tediosi, Bryan J Weiner, Elodie Yard, Judd Walson
Hybrid trials that include both clinical and implementation science outcomes are increasingly relevant for public health researchers that aim to rapidly translate study findings into evidence-based practice. The DeWorm3 Project is a series of hybrid trials testing the feasibility of interrupting the transmission of soil transmitted helminths (STH), while conducting implementation science research that contextualizes clinical research findings and provides guidance on opportunities to optimize delivery of STH interventions...
January 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29345179/regulatory-support-improves-subsequent-irb-approval-rates-in-studies-initially-deemed-not-ready-for-review-a-ctsa-institution-s-experience
#2
Susan Sonne, Stephanie Gentilin, Royce R Sampson, Leslie Bell, Toni Mauney, Summer Young, Katherine Bright, Patrick Flume
We evaluated the impact of a regulatory support service (known as the Regulatory Knowledge and Support [RKS] program), part of the Medical University of South Carolina's Clinical and Translational Science Award, on the success of Institutional Review Board (IRB) applications that have previously been deemed by the IRB to be Not Ready for Review (NRR). At the time of this evaluation, 77 studies had been deemed NRR, 53 of which came from trainees and junior faculty. All the applications that received regulatory support either received IRB approval or were deemed to not be research, and therefore did not require IRB review...
January 1, 2018: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/29343262/what-motivates-medical-students-to-select-medical-studies-a-systematic-literature-review
#3
Sonu Goel, Federica Angeli, Nonita Dhirar, Neetu Singla, Dirk Ruwaard
BACKGROUND: There is a significant shortage of health workers across and within countries. It is of utmost importance to determine the factors that motivate students to opt for medical studies. The objective of this study is to group and review all the studies that investigated the motivational factors that underpin students' selection of medical study in recent years. METHODS: The literature search was carried out by two researchers independently in PubMed, Google Scholar, Wiley and IndMED databases for articles published from year 2006 till 2016...
January 17, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29342071/why-we-should-care-about-the-sex-of-specimens-in-cadaveric-animal-and-cell-based-orthopaedic-research-commentary-on-an-article-by-jessica-bryant-md-et-al-potential-sex-bias-exists-in-orthopaedic-basic-science-and-translational-research
#4
https://www.readbyqxmd.com/read/29342062/potential-sex-bias-exists-in-orthopaedic-basic-science-and-translational-research
#5
Jessica Bryant, Paul Yi, Liane Miller, Kacy Peek, Daniel Lee
BACKGROUND: Potential sex bias has been shown in general surgery basic science and translational research, with unequal representation of male and female specimens. Because basic science research forms the foundation for clinical studies on which patient care is based, it is important that this research equally consider both sexes. The purpose of this study was to determine if potential sex bias exists in the basic science and translational orthopaedic literature. METHODS: A systematic review was conducted of all articles published in 2014 in The Journal of Bone & Joint Surgery, Clinical Orthopaedics and Related Research, The Bone & Joint Journal, and the Journal of Orthopaedic Research (JOR)...
January 17, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29341347/employing-the-arts-for-knowledge-production-and-translation-visualizing-new-possibilities-for-women-speaking-up-about-safety-concerns-in-maternity
#6
Nicola Mackintosh, Jane Sandall, Claire Collison, Wendy Carter, James Harris
OBJECTIVES: This project used animated film to translate research findings into accessible health information aimed at enabling women to speak up and secure professional help for serious safety concerns during pregnancy and after birth. We tested as proof of concept our use of the arts both as product (knowledge production) and process (enabling involvement). BACKGROUND: Emergencies during pregnancy and birth, while unusual, can develop rapidly and unexpectedly, with catastrophic consequences...
January 17, 2018: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/29339922/effect-of-rhythmic-auditory-cueing-on-gait-in-cerebral-palsy-a-systematic-review-and-meta-analysis
#7
REVIEW
Shashank Ghai, Ishan Ghai, Alfred O Effenberg
Auditory entrainment can influence gait performance in movement disorders. The entrainment can incite neurophysiological and musculoskeletal changes to enhance motor execution. However, a consensus as to its effects based on gait in people with cerebral palsy is still warranted. A systematic review and meta-analysis were carried out to analyze the effects of rhythmic auditory cueing on spatiotemporal and kinematic parameters of gait in people with cerebral palsy. Systematic identification of published literature was performed adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses and American Academy for Cerebral Palsy and Developmental Medicine guidelines, from inception until July 2017, on online databases: Web of Science, PEDro, EBSCO, Medline, Cochrane, Embase and ProQuest...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29337427/outcomes-from-the-first-helene-fuld-health-trust-national-institute-for-evidence-based-practice-in-nursing-and-healthcare-invitational-expert-forum
#8
Bernadette Mazurek Melnyk, Lynn Gallagher-Ford, Cindy Zellefrow, Sharon Tucker, Laurel Van Dromme, Bindu Koshy Thomas
BACKGROUND: Even though multiple positive outcomes are the result of evidence-based care, including improvements in healthcare quality, safety, and costs, it is not consistently delivered by clinicians in healthcare systems throughout the world. AIMS: In an attempt to accelerate the implementation of evidence-based practice (EBP) across the United States, an invitational Interprofessional National EBP Forum to determine major priorities for the advancement of EBP was held during the launch of the newly established Helene Fuld Health Trust National Institute for Evidence-Based Practice in Nursing and Healthcare at The Ohio State University College of Nursing...
January 16, 2018: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/29334943/training-programmes-to-improve-evidence-uptake-and-utilisation-by-physiotherapists-a-systematic-scoping-review
#9
Jessica Stander, Karen Grimmer, Yolandi Brink
BACKGROUND: Research training programmes are a knowledge translation (KT) intervention which aim to improve research evidence uptake by clinicians. Whilst KT training programmes have been reported to significantly improve evidence uptake by physiotherapists, it is unclear which aspects of training optimally assist KT into physiotherapy practice. The purpose of the review was to establish the body of evidence regarding KT training programmes to improve physiotherapists' use of evidence-based practice (EBP) and clinical practice guidelines (CPG)...
January 15, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29333363/creating-a-multi-center-rare-disease-consortium-the-consortium-of-eosinophilic-gastrointestinal-disease-researchers-cegir
#10
Katherine Cheng, Sandeep K Gupta, Susanna Kantor, Jonathan T Kuhl, Seema S Aceves, Peter A Bonis, Kelley E Capocelli, Christina Carpenter, Mirna Chehade, Margaret H Collins, Evan S Dellon, Gary W Falk, Rashmi Gopal-Srivastava, Nirmala Gonsalves, Ikuo Hirano, Eileen C King, John Leung, Jeffrey P Krischer, Vincent A Mukkada, Alain Schoepfer, Jonathan M Spergel, Alex Straumann, Guang-Yu Yang, Glenn T Furuta, Marc E Rothenberg
 Eosinophilic gastrointestinal disorders (EGIDs) affect various segments of the gastrointestinal tract. Since these disorders are rare, collaboration is essential to enroll subjects in clinical studies and study the broader population. The Rare Diseases Clinical Research Network (RDCRN), a program of the National Center for Advancing Translational Sciences (NCATS), funded the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) in 2014 to advance the field of EGIDs. CEGIR facilitates collaboration among various centers, subspecialties, patients, professional organizations and patient-advocacy groups and includes 14 clinical sites...
December 18, 2017: Translational Science of Rare Diseases
https://www.readbyqxmd.com/read/29331949/bibliometric-analysis-of-military-trauma-publications-2000-2016
#11
Mark L Vickers, C P Coorey, G J Milinovich, L Eriksson, M Assoum, M C Reade
INTRODUCTION: Bibliometric tools can be used to identify the authors, topics and research institutions that have made the greatest impact in a field of medicine. The aim of this research was to analyse military trauma publications over the last 16 years of armed conflict in order to highlight the most important lessons that have translated into civilian practice and military doctrine as well as identify emerging areas of importance. METHODS: A systematic search of research published between January 2000 and December 2016 was conducted using the Thompson Reuters Web of Science database...
January 13, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29329784/regulatory-science-an-underappreciated-component-of-translational-research
#12
Rodney Rouse, Issam Zineh, David G Strauss
Translational science refers to translating basic scientific findings to practical application (i.e., 'bench-to-bedside'). An underappreciated aspect of translational science is regulatory science. Herein, we focus on the importance of regulatory science to facilitate development of innovative new drugs and optimize use of approved drugs, with a call for community participation.
January 9, 2018: Trends in Pharmacological Sciences
https://www.readbyqxmd.com/read/29329724/the-potential-of-cold-plasma-for-safe-and-sustainable-food-production
#13
REVIEW
Paula Bourke, Dana Ziuzina, Daniela Boehm, Patrick J Cullen, Kevin Keener
Cold plasma science and technology is increasingly investigated for translation to a plethora of issues in the agriculture and food sectors. The diversity of the mechanisms of action of cold plasma, and the flexibility as a standalone technology or one that can integrate with other technologies, provide a rich resource for driving innovative solutions. The emerging understanding of the longer-term role of cold plasma reactive species and follow-on effects across a range of systems will suggest how cold plasma may be optimally applied to biological systems in the agricultural and food sectors...
November 30, 2017: Trends in Biotechnology
https://www.readbyqxmd.com/read/29328888/posterior-cruciate-ligament-reconstruction-with-transtibial-or-tibial-inlay-techniques-a-meta-analysis-of-biomechanical-and-clinical-outcomes
#14
Dong-Yeong Lee, Dong-Hee Kim, Hyun-Jung Kim, Hyeong-Sik Ahn, Tae-Ho Lee, Sun-Chul Hwang
BACKGROUND: Transtibial (TT) or tibial inlay (TI) techniques are commonly used for posterior cruciate ligament reconstruction (PCLR). However, the optimum method for PCLR after PCL injury remains debatable. Hypothesis/Purpose: The hypothesis was that TT and TI techniques would not show significant differences for all outcome measures. The purpose was to determine the biomechanical and clinical outcomes of TT and TI surgical techniques for PCLR. STUDY DESIGN: Meta-analysis; Level of evidence, 3...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29328872/the-sustainability-of-evidence-based-interventions-and-practices-in-public-health-and-health-care
#15
Rachel C Shelton, Brittany Rhoades Cooper, Shannon Wiltsey Stirman
There is strong interest in implementation science to address the gap between research and practice in public health. Research on the sustainability of evidence-based interventions has been growing rapidly. Sustainability has been defined as the continued use of program components at sufficient intensity for the sustained achievement of desirable program goals and population outcomes. This understudied area has been identified as one of the most significant translational research problems. Adding to this challenge is uncertainty regarding the extent to which intervention adaptation and evolution are necessary to address the needs of populations that differ from those in which interventions were originally tested or implemented...
January 12, 2018: Annual Review of Public Health
https://www.readbyqxmd.com/read/29320606/splitting-water-by-electrochemistry-and-artificial-photosynthesis-excellent-science-but-a-nightmare-of-translation
#16
REVIEW
Markus Antonietti, Alexandr Savateev
Water splitting to its elements, either by electrochemistry or by solar light, is among the most covered areas in nanostructured functional materials. This personal account article analyzes potential downstream translation problems and reviews alternative chemistries with a potential higher return. Liberation of oxygen for accepting the holes is a kinetically demanding half reaction afflicted with kinetic hindrances and high overpotentials, while at the same time no marketable value is created (atmospheric oxygen is free to use)...
January 10, 2018: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/29318629/tony-nevin-the-embrace-of-translational-work-by-a-basic-scientist
#17
F Charles Mace
Here I summarize John A. "Tony" Nevin's evolution as a translational author. All of his publications were classified by title and content as being primarily experimental analysis of behavior or translational. Translational works were subtyped as interpretative, descriptive research, or experimental research. During the first 20 years of his publication career, Tony published exclusively experimental analysis of behavior work. In 1982, he began a series of interpretative translational analyses on topics of significant social importance...
January 10, 2018: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/29318094/translational-chemistry-the-future-in-science
#18
EDITORIAL
Carlos Lodeiro, Jose Luis Capelo
No abstract text is available yet for this article.
January 2018: ChemistryOpen
https://www.readbyqxmd.com/read/29316362/concise-review-fabrication-customization-and-application-of-cell-mimicking-microparticles-in-stem-cell-science
#19
REVIEW
Nicholas R Labriola, Aharon Azagury, Robert Gutierrez, Edith Mathiowitz, Eric M Darling
Stem and non-stem cell behavior is heavily influenced by the surrounding microenvironment, which includes other cells, matrix, and potentially biomaterials. Researchers have been successful in developing scaffolds and encapsulation techniques to provide stem cells with mechanical, topographical, and chemical cues to selectively direct them toward a desired differentiation pathway. However, most of these systems fail to present truly physiological replications of the in vivo microenvironments that stem cells are typically exposed to in tissues...
January 9, 2018: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/29314819/modulating-phagocytic-cell-sequestration-by-tailoring-nanoconstruct-softness
#20
Roberto Palomba, Anna Lisa Palange, Ilaria Francesca Rizzuti, Miguel Ferreira, Antonio Cervadoro, Maria Grazia Barbato, Claudio Canale, Paolo Decuzzi
The effect of nanoparticle size, shape and surface properties on cellular uptake has been extensively investigated for its basic science and translational implications. Recently, softness is emerging as a design parameter for modulating the interaction of nanoparticles with cells and the biological microenvironment. Here, circular, quadrangular and elliptical polymeric nanoconstructs of different sizes are realized with a Young's modulus ranging from ∽ 100 kPa (soft) to 10 MPa (rigid). The interaction of these nanoconstructs with professional phagocytic cells is assessed via confocal microscopy and flow cytometry analyses...
January 9, 2018: ACS Nano
keyword
keyword
107472
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"