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"Chronic kidney" and depression

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https://www.readbyqxmd.com/read/27856785/chronic-obstructive-pulmonary-disease-phenotypes-using-cluster-analysis-of-electronic-medical-records
#1
Rodrigo Vazquez Guillamet, Oleg Ursu, Gary Iwamoto, Pope L Moseley, Tudor Oprea
Chronic obstructive pulmonary disease is a heterogeneous disease. In this retrospective study, we hypothesize that it is possible to identify clinically relevant phenotypes by applying clustering methods to electronic medical records. We included all the patients >40 years with a diagnosis of chronic obstructive pulmonary disease admitted to the University of New Mexico Hospital between 1 January 2011 and 1 May 2014. We collected admissions, demographics, comorbidities, severity markers and treatments...
November 17, 2016: Health Informatics Journal
https://www.readbyqxmd.com/read/27832762/tryptophan-metabolism-its-relation-to-inflammation-and-stress-markers-and-association-with-psychological-and-cognitive-functioning-tasmanian-chronic-kidney-disease-pilot-study
#2
Naama Karu, Charlotte McKercher, David S Nichols, Noel Davies, Robert A Shellie, Emily F Hilder, Matthew D Jose
BACKGROUND: Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation. Indoles produced by gut-microflora are another group of tryptophan metabolites related to inflammation and conditions accompanying CKD. Disruptions in tryptophan metabolism have been associated with various neurological and psychological disorders. A high proportion of CKD patients self-report symptoms of depression and/or anxiety and decline in cognitive functioning...
November 10, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27729238/associations-between-cardiovascular-disease-risk-factors-and-il-6-and-hscrp-levels-in-the-elderly
#3
Paweł Nadrowski, Jerzy Chudek, Michał Skrzypek, Monika Puzianowska-Kuźnicka, Małgorzata Mossakowska, Andrzej Więcek, Tomasz Zdrojewski, Tomasz Grodzicki, Krystyna Kozakiewicz
BACKGROUND: Age-related diseases, including cardiovascular diseases (CVD) may be stimulated by microinflammation, marked by increased level of IL-6 and high-sensitivity CRP (hsCRP). We aimed to investigate whether aging "per se" independently contributesto themicroinflammation,inadditionto traditional and novel CVD risk factors. METHODS/RESULTS: The research sample included 4979 participants from PolSenior Study, aged over 65years. The study consisted of threevisitsandincludedquestionnairesurvey,geriatricassessmentandblood/urinesamplingin4101 participants (83...
October 8, 2016: Experimental Gerontology
https://www.readbyqxmd.com/read/27720260/dissonant-health-transition-in-the-states-of-mexico-1990-2013-a-systematic-analysis-for-the-global-burden-of-disease-study-2013
#4
Héctor Gómez-Dantés, Nancy Fullman, Héctor Lamadrid-Figueroa, Lucero Cahuana-Hurtado, Blair Darney, Leticia Avila-Burgos, Ricardo Correa-Rotter, Juan A Rivera, Simon Barquera, Eduardo González-Pier, Tania Aburto-Soto, Elga Filipa Amorin de Castro, Tonatiuh Barrientos-Gutiérrez, Ana C Basto-Abreu, Carolina Batis, Guilherme Borges, Ismael Campos-Nonato, Julio C Campuzano-Rincón, Alejandra de Jesús Cantoral-Preciado, Alejandra G Contreras-Manzano, Lucia Cuevas-Nasu, Vanessa V de la Cruz-Gongora, Jose L Diaz-Ortega, María de Lourdes García-García, Armando Garcia-Guerra, Teresita González de Cossío, Luz D González-Castell, Ileana Heredia-Pi, Marta C Hijar-Medina, Alejandra Jauregui, Aida Jimenez-Corona, Nancy Lopez-Olmedo, Carlos Magis-Rodríguez, Catalina Medina-Garcia, Maria E Medina-Mora, Fabiola Mejia-Rodriguez, Julio C Montañez, Pablo Montero, Alejandra Montoya, Grea L Moreno-Banda, Andrea Pedroza-Tobías, Rogelio Pérez-Padilla, Amado D Quezada, Vesta L Richardson-López-Collada, Horacio Riojas-Rodríguez, Maria J Ríos Blancas, Christian Razo-Garcia, Martha P Romero Mendoza, Tania G Sánchez-Pimienta, Luz M Sánchez-Romero, Astrid Schilmann, Edson Servan-Mori, Teresa Shamah-Levy, Martha M Téllez-Rojo, José L Texcalac-Sangrador, Haidong Wang, Theo Vos, Mohammad H Forouzanfar, Mohsen Naghavi, Alan D Lopez, Christopher J L Murray, Rafael Lozano
BACKGROUND: Child and maternal health outcomes have notably improved in Mexico since 1990, whereas rising adult mortality rates defy traditional epidemiological transition models in which decreased death rates occur across all ages. These trends suggest Mexico is experiencing a more complex, dissonant health transition than historically observed. Enduring inequalities between states further emphasise the need for more detailed health assessments over time. The Global Burden of Diseases, Injuries, and Risk Factors Study 2013 (GBD 2013) provides the comprehensive, comparable framework through which such national and subnational analyses can occur...
October 5, 2016: Lancet
https://www.readbyqxmd.com/read/27688858/is-it-possible-to-delay-or-prevent-age-related-cognitive-decline
#5
REVIEW
Jean-Pierre Michel
Already in the 90s, Khachaturian stated that postponing dementia onset by five years would decrease the prevalence of the late onset dementia by 50%. After two decades of lack of success in dementia drug discovery and development, and knowing that worldwide, currently 36 million patients have been diagnosed with Alzheimer's disease, a number that will double by 2030 and triple by 2050, the World Health Organization and the Alzheimer's Disease International declared that prevention of cognitive decline was a 'public health priority...
September 2016: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/27680506/influence-of-cerebral-white-matter-hyperintensities-on-cognitive-impairment-in-elderly-medical-patients
#6
Koichi Shibata, Yoshiko Nishimura, Kuniaki Otsuka, Hiroshi Sakura
AIM: We investigated the characteristics of elderly medical patients with white matter hyperintensities on magnetic resonance imaging. METHODS: A total of 213 patients (123 men and 90 women; mean age 74.8 years) reported their history of hypertension, diabetes, dyslipidemia, previous stroke, coronary heart disease and chronic kidney disease (CKD). All patients completed the Mini-Mental State Examination and Geriatric Depression Scale. White matter hyperintensities were evaluated for the periventricular region, basal ganglia (BGH), deep white matter and infratentorial region, and brain atrophy was calculated as bicaudate ratios...
September 29, 2016: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/27678345/c-reactive-protein-and-depressive-symptoms-in-haemodialysis-patients-a-questionable-association
#7
Joseph Chilcot, Karin Friedli, Ayman Guirguis, David Wellsted, Ken Farrington, Andrew Davenport
Introduction Patients with advanced chronic kidney disease (CKD) on haemodialysis (HD) may have increased C reactive protein (CRP) values and depressive symptoms. There is debate about the strength and nature of previously reported associations. We investigated these issues in a cohort of patients on HD. Methods We screened for depressive symptoms using two valadiated depression screening tools: the Beck Depression Inventory-II (BDI-II), Patient Health Questionnaire (PHQ-9). Demographic and clinical correlates of depression symptoms were eveluated in adjusted linear and logistic regression models, which included extra renal comorbidity and high CRP (>5 mg/L)...
September 27, 2016: Hemodialysis International
https://www.readbyqxmd.com/read/27663114/examining-internet-delivered-cognitive-behaviour-therapy-for-patients-with-chronic-kidney-disease-on-haemodialysis-a-feasibility-open-trial
#8
Ramony Chan, Blake F Dear, Nick Titov, Josephine Chow, Michael Suranyi
OBJECTIVE: Treating depression among patients with chronic kidney disease (CKD) is imperative because of its high prevalence and health-related costs. However, many patients with CKD experience significant barriers to effective face-to-face psychological treatments. Internet-delivered cognitive behaviour therapy (iCBT) may help overcome the treatment barriers. The aim of the present study was to explore the acceptability and preliminary efficacy of iCBT for depression and anxiety among patients with CKD on haemodialysis...
October 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27638974/performance-of-depression-rating-scales-in-patients-with-chronic-kidney-disease-an-item-response-theory-based-analysis
#9
Marisa Toups, Thomas Carmody, Madhukar H Trivedi, A John Rush, S Susan Hedayati
OBJECTIVE: Because there is overlap between somatic symptoms of depression and symptoms of chronic kidney disease (CKD), it is unclear if self-reported depression rating scales can be used accurately in predialysis CKD patients, especially if CKD and other comorbidities are symptomatic. We assessed the performance of two depression scales - the Beck Depression Inventory (BDI) and the Quick Inventory of Depression Symptomatology (QIDS-SR16) - by CKD stage, diagnosis of diabetes and total medical comorbidity burden - using item response theory (IRT) in a sample of 272 predialysis CKD patients...
September 2016: General Hospital Psychiatry
https://www.readbyqxmd.com/read/27612446/design-and-protocol-for-the-dialysis-optimal-health-program-dohp-randomised-controlled-trial
#10
Simon R Knowles, Chantal F Ski, Robyn Langham, Emmet O'Flaherty, David R Thompson, Susan L Rossell, Gaye Moore, Ya-Seng Arthur Hsueh, David J Castle
BACKGROUND: Chronic kidney disease (CKD) and end-stage kidney disease (ESKD) are serious and growing health problems with enormous impact on psychological and social functioning. Despite high rates of comorbid depression and anxiety in these patient populations, and the adverse impact these have upon treatment adherence, quality of life, social connectedness and healthcare costs there has been little attention focused on the prevention or management of these problems. Thus, our aim was to evaluate the Dialysis Optimal Health Program (DOHP) that adopts a person-centred approach and engages collaborative therapy to educate and support those diagnosed with ESKD who are commencing dialysis...
2016: Trials
https://www.readbyqxmd.com/read/27592294/prognostic-utility-of-a-self-reported-depression-questionnaire-versus-clinician-based-assessment-on-renal-outcomes
#11
Nishank Jain, Thomas Carmody, Abu T Minhajuddin, Marisa Toups, Madhukar H Trivedi, Augustus John Rush, S Susan Hedayati
BACKGROUND: The prognostic utility of self-administered depression scales in chronic kidney disease (CKD) independent of a clinician-based major depressive disorder (MDD) diagnosis is neither clearly established nor are the optimal cutoff scores for predicting outcomes. The overlap between symptoms of depression and chronic disease raises the question of whether a cutoff score on a depression scale can be substituted for a time-consuming diagnostic interview to prognosticate risk. METHODS: The 16-item Quick Inventory of Depression Symptomatology-Self Report scale (QIDS-SR16) was administered to 266 consecutive outpatients with non-dialysis CKD, followed prospectively for 12 months for an apriori composite outcome of death or dialysis or hospitalization...
2016: American Journal of Nephrology
https://www.readbyqxmd.com/read/27555505/blood-pressure-sexual-activity-and-dysfunction-in-women-with-hypertension-baseline-findings-from-the-systolic-blood-pressure-intervention-trial-sprint
#12
Capri G Foy, Jill C Newman, Dan R Berlowitz, Laurie P Russell, Paul L Kimmel, Virginia G Wadley, Holly N Thomas, Alan J Lerner, William T Riley
INTRODUCTION: Sexual function, an important component of quality of life, is gaining increased research and clinical attention in older women with hypertension. AIM: To assess the association between systolic blood pressure (SBP) and other variables, and sexual activity and sexual dysfunction in hypertensive women. METHODS: Baseline analysis of 635 women participants of a larger randomized clinical trial of 9361 men and women. MAIN OUTCOME MEASURES: Self-reported sexual activity (yes/no), and sexual function using the Female Sexual Function Inventory (FSFI)...
September 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27545627/sagliker-syndrome-first-four-cases-in-bulgaria
#13
R Cholakova, Petia Pechalova, E Kapon
UNLABELLED: Sagliker syndrome characterized with uglifying the appearance of the face due to secondary hyperparathyroidism in patients with chronic renal failure receiving dialysis long time ago. The aim of the study was to identify any patients with Sagliker syndrome among the 78 patients receiving dialysis at the Dialysis ward, University Hospital "St. George", Plovdiv, Bulgaria. RESULTS: Four patients metthe criteria for Sagliker syndrome: chronic renal insufficiency, secondary hyperparathyroidism, short stature, severe changes in the skull and jaw that lead to festoon-like uglifying face, dental abnormalities, "brown" tumors, deformations of the phalanges of the fingers, psychological diseases and depression...
July 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/27505201/-are-we-overestimating-the-prevalence-of-depression-in-chronic-illness-using-questionnaires-meta-analytic-evidence-in-obstructive-sleep-apnoea-correction-to-nanthakumar-et-al-2016
#14
(no author information available yet)
UNLABELLED: Reports an error in "Are we overestimating the prevalence of depression in chronic illness using questionnaires? Meta-analytic evidence in obstructive sleep apnoea" by Shenooka Nanthakumar, Romola S. Bucks and Timothy C. Skinner (, 2016[May], Vol 35[5], 423-432). In the article, "Cognitive items" should read "Cognition items" in column 1, line 7 of Table 2. (The following abstract of the original article appeared in record .) INTRODUCTION: Depression is common in chronic illness, albeit prevalence can be highly variable...
August 2016: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/27493078/a-highly-reproducible-mice-model-of-chronic-kidney-disease-evidences-of-behavioural-abnormalities-and-blood-brain-barrier-disruption
#15
Muhammed Khairujjaman Mazumder, Anirudha Giri, Sanjeev Kumar, Anupom Borah
AIMS: In the present study, a novel mice model of chronic kidney disease (CKD) was developed, and psycho-motor behavioural abnormalities, blood-brain barrier (BBB) integrity and brain histology were studied. MAIN METHODS: Swiss albino female mice were given high adenine diet (0.3% w/w mixed with feed) for 4weeks. Serum urea and creatinine levels and renal histological studies were performed to validate the model. Psycho-motor behavioural abnormalities and neurological severity were studied...
September 15, 2016: Life Sciences
https://www.readbyqxmd.com/read/27475661/consequences-of-ckd-on-functioning
#16
REVIEW
Piyawan Kittiskulnam, Anoop Sheshadri, Kirsten L Johansen
Chronic kidney disease (CKD) is highly prevalent in the United States and throughout the world,(1) with approximately 13% of adults affected.(2) In addition, according to recent estimates, almost half of patients with CKD stages 3 to 5 are 70 years of age and older.(2) In the United States, the number of prevalent end-stage renal disease cases continues to increase in patients older than age 65. In light of the demographic characteristics of patients with CKD and ESRD, there has been considerable focus on associations between CKD and cardiovascular outcomes...
July 2016: Seminars in Nephrology
https://www.readbyqxmd.com/read/27441482/factors-associated-with-tobacco-use-among-patients-with-multiple-chronic-conditions
#17
Arise Garcia de Siqueira Galil, Ana Paula Cupertino, Eliane F C Banhato, Tatiane S Campos, Fernando A B Colugnati, Kimber P Richter, Marcus G Bastos
BACKGROUND: Cigarette smoking is an important risk factor for disease onset and progression among the major chronic diseases accounting for most morbidity and mortality in the world. Our objective was to identify characteristics associated with tobacco use among patients with multiple chronic conditions (MCC). METHODS: This cross-sectional study was implemented at the Center HIPERDIA Minas Juiz de Fora, Brazil, which manages patients with high cardiovascular risk, hypertension, diabetes mellitus and chronic kidney disease...
October 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27399102/association-between-gastroesophageal-reflux-disease-and-coronary-heart-disease-a-nationwide-population-based-analysis
#18
Chien-Hua Chen, Cheng-Li Lin, Chia-Hung Kao
In this study, we aimed to determine the association between gastroesophageal reflux disease (GERD) and subsequent coronary heart disease (CHD) development, if any, and to evaluate whether longer use of proton pump inhibitors (PPIs) increases the risk of CHD.Patients diagnosed with GERD between 2000 and 2011 were identified as the study cohort (n = 12,960). Patients without GERD were randomly selected from the general population, frequency-matched with the study group according to age, sex, and index year, and evaluated as the comparison cohort (n = 51,840)...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27357223/molecular-mechanisms-in-lithium-associated-renal-disease-a-systematic-review
#19
Soham Rej, Shamira Pira, Victoria Marshe, André Do, Dominique Elie, Karl J Looper, Nathan Herrmann, Daniel J Müller
PURPOSE: Lithium is an essential treatment in bipolar disorder and treatment-resistant depression; however, its use has been limited by concerns regarding its renal adverse effects. An improved understanding of potential molecular mechanisms can help develop prevention and treatment strategies for lithium-associated renal disease. METHODS: We conducted a systematic literature search using MEDLINE, Embase, and PsychINFO including English-language original research articles published prior to November 2015 that specifically investigated lithium's effects on nephrogenic diabetes insipidus (NDI) and chronic kidney disease (CKD), using molecular markers...
June 29, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27349639/acupuncture-and-related-interventions-for-symptoms-of-chronic-kidney-disease
#20
REVIEW
Kun Hyung Kim, Myeong Soo Lee, Tae-Hun Kim, Jung Won Kang, Tae-Young Choi, Jae Dong Lee
BACKGROUND: People living with chronic kidney disease (CKD) experience a range of symptoms and often have complex comorbidities. Many pharmacological interventions for people with CKD have known risks of adverse events. Acupuncture is widely used for symptom management in patients with chronic diseases and in other palliative care settings. However, the safety and efficacy of acupuncture for people with CKD remains largely unknown. OBJECTIVES: We aimed to evaluate the benefits and harms of acupuncture, electro-acupuncture, acupressure, moxibustion and other acupuncture-related interventions (alone or combined with other acupuncture-related interventions) for symptoms of CKD...
2016: Cochrane Database of Systematic Reviews
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