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JOURNAL ARTICLE
Jon Raso, Pramod Kamalapathy, Eric Solomon, Elizabeth Driskill, Kristina Kurker, Aditya Joshi, Hamid Hassanzadeh
STUDY DESIGN: Retrospective Cohort Study. OBJECTIVES: Although the optimal timing of surgical intervention for traumatic spinal cord injury (TSCI) is controversial, early intervention has been recognized as being beneficial in several studies. The objective of this study was to evaluate the socioeconomic factors that may delay time to surgical fixation in the management of TSCI. METHODS: The present study utilized the Trauma Quality Improvement Program (TQIP) dataset to identify patients aged greater than 18 undergoing spinal fusion for TSCI from 2007-2016...
February 5, 2024: Global Spine Journal
#22
JOURNAL ARTICLE
Hyun-Hee Choi, Hana Ahn, Won-Sang Jung
PURPOSE: This study aims to develop a regression model to estimate peak oxygen consumption (VO2peak) in individuals with spinal cord injury (SCI) by employing different variables. METHODS: In this study, 34 participants were divided into two groups: 19 with cervical injury (CI) and 15 with thoracic injury (TI). Key measurements included VO2peak and related factors such as age, height, weight, body mass index (BMI), fat-free mass, body fat percentage, limb and trunk circumferences, spinal cord independence (SCIM III), Korean activities of daily living (K-ADL), and respiratory functions (forced vital capacity (FVC), peak expiratory flow (PEF), and maximum voluntary ventilation (MVV))...
December 2023: Physical activity and nutrition
#23
JOURNAL ARTICLE
Paul Stacey, Arun Mensinkai, Pankaj Bansal, Seyed-Hossein Hosseini, Andrew Lavigne, Basia Gwardjan, Sayna Leylachian, Zhihui Joy Deng, Vinjamuri Chari, Sandra Giles, Shanker Nesathurai
Traumatic spinal cord injury (TSCI) is a significant public health challenge that has an adverse impact on functional independence, quality of life, and life expectancy. Management of people's chronic conditions is a key aspect of contemporary medical practice. Our study was an open label, single arm, prospective pilot study to evaluate the feasibility of treating people with TSCI. The study intervention was treatment with oral selenium and vitamin E. Participants were 18 years or older and experienced a TSCI at least one year prior to enrollment...
January 4, 2024: Pharmaceuticals
#24
JOURNAL ARTICLE
Beining Yang, Weimin Zheng, Ling Wang, Yulong Jia, Qunya Qi, Haotian Xin, Yu Wang, Tengfei Liang, Xin Chen, Qian Chen, Baowei Li, Jubao Du, Yongsheng Hu, Jie Lu, Nan Chen
BACKGROUND: The alternation of brain white matter (WM) network has been studied in adult spinal cord injury (SCI) patients. However, the WM network alterations in pediatric SCI patients remain unclear. PURPOSE: To evaluate WM network changes and their functional impact in children with thoracolumbar SCI (TSCI). STUDY TYPE: Prospective. SUBJECTS: Thirty-five pediatric patients with TSCI (8.94 ± 1.86 years, 8/27 males/females) and 34 age- and gender-matched healthy controls (HCs) participated in this study...
January 19, 2024: Journal of Magnetic Resonance Imaging: JMRI
#25
JOURNAL ARTICLE
Mei-Hua Cheng, Shu-O Chiang, Chen-Yi Wang, Kuo-Ting Chang, Wei-Jie Wang
CONTEXT: Patients with spinal cord injury (SCI) can develop urinary tract stones (UTSs) up to years after the injury, which is especially common in the first few months. However, relevant epidemiological studies and up-to-date epidemiological data for SCI in Taiwan are lacking. PURPOSE: To estimate SCI and SCI-induced UTS incidence and trauma severity, neurological deficits, and injury site in patients with SCI-induced UTSs in Taiwan. DESIGN: Retrospective cohort study...
January 19, 2024: Journal of Spinal Cord Medicine
#26
JOURNAL ARTICLE
Edoardo Picetti, Andreas K Demetriades, Fausto Catena, Bizhan Aarabi, Fikri M Abu-Zidan, Oscar L Alves, Luca Ansaloni, Rocco A Armonda, Rafael Badenes, Miklosh Bala, Zsolt J Balogh, Andrea Barbanera, Alessandro Bertuccio, Walter L Biffl, Pierre Bouzat, Andras Buki, Ana Maria Castano-Leon, Davide Cerasti, Giuseppe Citerio, Federico Coccolini, Raul Coimbra, Carlo Coniglio, Francesco Costa, Federico De Iure, Bart Depreitere, Enrico Fainardi, Michael J Fehlings, Nikolay Gabrovsky, Daniel Agustin Godoy, Peter Gruen, Deepak Gupta, Gregory W J Hawryluk, Raimund Helbok, Iftakher Hossain, Peter J Hutchinson, Corrado Iaccarino, Kenji Inaba, Marcel Ivanov, Stanislav Kaprovoy, Andrew W Kirkpatrick, Sam Klein, Angelos Kolias, Nikolay A Konovalov, Alfonso Lagares, Laura Lippa, Angelica Loza-Gomez, Teemu M Luoto, Andrew I R Maas, Andrzej Maciejczak, Ronald V Maier, Niklas Marklund, Matthew J Martin, Ilaria Melloni, Sergio Mendoza-Lattes, Geert Meyfroidt, Marina Munari, Lena M Napolitano, David O Okonkwo, Yasuhiro Otomo, Marios C Papadopoulos, Ondra Petr, Wilco C Peul, Aichholz K Pudkrong, Zaffer Qasim, Frank Rasulo, Carla Reizinho, Florian Ringel, Sandro Rizoli, Elham Rostami, Andres M Rubiano, Emanuele Russo, Aarti Sarwal, Jan M Schwab, Franco Servadei, Deepak Sharma, Salman Sharif, Ehab Shiban, Lori Shutter, Philip F Stahel, Fabio S Taccone, Nicole A Terpolilli, Claudius Thomé, Peter Toth, Parmenion P Tsitsopoulos, Andrew Udy, Alexander R Vaccaro, Albert J Varon, Monica S Vavilala, Alexander Younsi, Monika Zackova, Tommaso Zoerle, Chiara Robba
BACKGROUND: The early management of polytrauma patients with traumatic spinal cord injury (tSCI) is a major challenge. Sparse data is available to provide optimal care in this scenario and worldwide variability in clinical practice has been documented in recent studies. METHODS: A multidisciplinary consensus panel of physicians selected for their established clinical and scientific expertise in the acute management of tSCI polytrauma patients with different specializations was established...
January 18, 2024: World Journal of Emergency Surgery: WJES
#27
JOURNAL ARTICLE
Fater A Khadour, Younes A Khadour, Ling Meng, Cui XinLi, Tao Xu
Spinal cord injuries are incredibly disabling and can have fatal consequences. At present, there is a lack of available information regarding the epidemiological characteristics of patients who have experienced spinal cord injury (SCI) in China. This retrospective hospital-based study was conducted in the Rehabilitation department of Wuhan's Tongji Hospital between 2016 and 2022. A total of 649 individuals diagnosed with SCI (both traumatic and non-traumatic) were admitted during this period. Data regarding various epidemiological features were gathered, including sex, age, etiology, occupation, neurological level of injury, the American Spinal Injury Association Impairment Scale at the time of admission, and information on any accompanying injuries...
January 18, 2024: Scientific Reports
#28
REVIEW
Yoonjeong Choi, Ja-Ho Leigh
This review describes the incidence rates and trends of traumatic spinal cord injuries (TSCI) and non-traumatic spinal cord injuries (NTSCI) in South Korea. The incidence of NTSCI has increased more rapidly than that of TSCI in recent years. In 2007, TSCI was more common, but by 2020, NTSCI had surpassed TSCI, particularly in older individuals. While men have a higher incidence of both TSCI and NTSCI, the incidence difference by sex is greater in TSCI. The incidence rates of both TSCI and NTSCI are higher in older individuals, particularly those in their 70s and 80s...
December 2023: Korean Journal of Neurotrauma
#29
JOURNAL ARTICLE
Changyi Wang, Mingxi Chen, Tiantian Wang, Yihan Wang, Yuyi Zhu, Ting Cui, Zilong Hao, Deren Wang, Chengqi He
PURPOSE: The overwhelming inflammatory response plays a critical role in the secondary injury cascade of traumatic spinal cord injury (tSCI). The systemic immune inflammatory index (SII) and systemic inflammatory response index (SIRI) are two novel inflammatory biomarkers. The SII was calculated based on lymphocyte, neutrophil, and platelet counts, while the SIRI was calculated based on lymphocyte, neutrophil, and monocyte counts. Their prognostic value in patients with tSCI remains unclear...
March 2024: European Spine Journal
#30
JOURNAL ARTICLE
Tej D Azad, Divyaansh Raj, Kathleen R Ran, Vikas N Vattipally, Anmol Warman, Micheal Raad, John R Williams, Daniel Lubelski, Elliott R Haut, Jose I Suarez, Ali Bydon, Timothy F Witham, Christopher D Witiw, Nicholas Theodore, James P Byrne
BACKGROUND AND OBJECTIVES: Growing evidence supports prompt surgical decompression for patients with traumatic spinal cord injury (tSCI). Rates of concomitant tSCI and traumatic brain injury (TBI) range from 10% to 30%. Concomitant TBI may delay tSCI diagnosis and surgical intervention. Little is known about real-world management of this common injury constellation that carries significant clinical consequences. This study aimed to quantify the impact of concomitant TBI on surgical timing in a national cohort of patients with tSCI...
January 10, 2024: Neurosurgery
#31
JOURNAL ARTICLE
Osama Neyaz, Vinay Kanaujia, Raj Kumar Yadav, Bhaskar Sarkar, Md Quamar Azam, Pankaj Kandwal
OBJECTIVE: To compile epidemiological characteristics of traumatic spinal cord injury (TSCI) in the Northern Indian Himalayan regions and Sub-Himalayan planes. METHODS: The present study is a retrospective, cross-sectional descriptive analysis based on hospital data conducted at the Department of Physical Medicine and Rehabilitation and Spine Unit of Trauma Centre in a tertiary care hospital in Uttarakhand, India. People hospitalized at the tertiary care center between August 2018 and November 2021 are included in the study sample...
December 26, 2023: Annals of Rehabilitation Medicine
#32
REVIEW
Mohammad Mofatteh, Mohammad Sadegh Mashayekhi, Saman Arfaie, Yimin Chen, Armaan K Malhotra, Georgios P Skandalakis, Mohammed Ali Alvi, Fardad T Afshari, Shakila Meshkat, Famu Lin, Ebtesam Abdulla, Ayush Anand, Xuxing Liao, Roger S McIntyre, Carlo Santaguida, Michael H Weber, Michael G Fehlings
BACKGROUND: Traumatic spinal cord injury (TSCI) is a debilitating neurological condition with significant long-term consequences on the mental health and well-being of affected individuals. We aimed to investigate anxiety and depression in individuals with pediatric-onset TSCI. METHODS: PubMed, Scopus, and Web of Science databases were searched from inception to December 20th, 2022 following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, and studies were included according to the eligibility criteria...
April 2024: World Neurosurgery
#33
JOURNAL ARTICLE
Ramtin Hakimjavadi, Heather A Hong, Nader Fallah, Suzanne Humphreys, Stephen Kingwell, Alexandra Stratton, Eve Tsai, Eugene K Wai, Kristen Walden, Vanessa K Noonan, Philippe Phan
INTRODUCTION: Several clinical prediction rules (CPRs) have been published, but few are easily accessible or convenient for clinicians to use in practice. We aimed to develop, implement, and describe the process of building a web-based CPR for predicting independent walking 1-year after a traumatic spinal cord injury (TSCI). METHODS: Using the published and validated CPR, a front-end web application called "Ambulation" was built using HyperText Markup Language (HTML), Cascading Style Sheets (CSS), and JavaScript...
2023: Frontiers in Neurology
#34
JOURNAL ARTICLE
Craig Mitton, Francois Dionne, Nader Fallah, Vanessa K Noonan
BACKGROUND: A previous analysis using the Canadian Spinal Cord Injury (SCI) Community Survey data identified that there were individuals with a high number of secondary health conditions, high health care utilization, poor health outcomes, and unmet health care needs. OBJECTIVES: The objectives of this study were to estimate the annual health care costs of persons with SCI who report secondary health conditions, and to determine the association between these secondary health conditions with health care utilization and self-reported life satisfaction and quality of life...
2023: Topics in Spinal Cord Injury Rehabilitation
#35
REVIEW
Wenqi Luo, Yueying Li, Chunyu Xiang, Toshimi Aizawa, Renrui Niu, Yiming Wang, Jianhui Zhao, Zeping Liu, Chaoyuan Li, Wanguo Liu, Rui Gu
Promoting the recovery of neurological function in patients with traumatic spinal cord injury (TSCI) remains challenging. The balance between astrocyte-mediated neurotrophic and pro-inflammatory responses is critical for TSCI repair. Recently, the utilization of nanomaterials has been considerably explored in immunological reconstructive techniques that specifically target astrocyte-mediated inflammation, yielding positive outcomes. In this review, we aim to condense the present knowledge regarding the astrocyte-mediated inflammation following TSCI...
December 2023: Materials today. Bio
#36
JOURNAL ARTICLE
Mehdi Mahmoodkhani, Majid Rezvani, Arman Farshin, Pouria Ghasemi, Donya Sheibani Tehrani
BACKGROUND: Spinal cord injury (SCI) is the second cause of complications and disability after brain injury. Although primary prevention is the best strategy, obtaining the necessary knowledge about the patient's condition and follow-up treatment can lead to the use of safety measures and appropriate healthcare planning. This is the basis of this study with the aim of a two-year follow-up of patients with traumatic SCI (TSCI) who underwent surgery. MATERIALS AND METHODS: This study was a descriptive and analytical type that examined 79 patients with TSCI who had undergone surgery two years ago...
2023: Advanced Biomedical Research
#37
JOURNAL ARTICLE
James A G Crispo, Lisa J W Liu, Vanessa K Noonan, Nancy P Thorogood, Brian K Kwon, Marcel F Dvorak, Dylan Thibault, Allison W Willis, Jacquelyn J Cragg
INTRODUCTION: Traumatic spinal cord injury (tSCI) is a debilitating neurological condition resulting in lifelong disability for many individuals. The primary objectives of our study were to describe national trends in incident emergency department (ED) visits for tSCI among children (less than 21 years) in the United States, and to determine the proportion of visits that resulted in immediate hospitalization each year, including stratified by age and sex. Secondary objectives were to examine associations between select characteristics and hospitalization following tSCI, as well as to assess sports-related tSCIs over time, including by individual sport and geographic region...
2023: Frontiers in Neurology
#38
JOURNAL ARTICLE
Dea Mahanes, Susanne Muehlschlegel, Katja E Wartenberg, Venkatakrishna Rajajee, Sheila A Alexander, Katharina M Busl, Claire J Creutzfeldt, Gabriel V Fontaine, Sara E Hocker, David Y Hwang, Keri S Kim, Dominik Madzar, Shraddha Mainali, Juergen Meixensberger, Panayiotis N Varelas, Christian Weimar, Thomas Westermaier, Oliver W Sakowitz
BACKGROUND: Traumatic spinal cord injury (tSCI) impacts patients and their families acutely and often for the long term. The ability of clinicians to share prognostic information about mortality and functional outcomes allows patients and their surrogates to engage in decision-making and plan for the future. These guidelines provide recommendations on the reliability of acute-phase clinical predictors to inform neuroprognostication and guide clinicians in counseling adult patients with tSCI or their surrogates...
April 2024: Neurocritical Care
#39
JOURNAL ARTICLE
Wu Zhou, Yihao Liu, Zhihua Wang, Zelu Mao, Meihua Li
OBJECTIVE: Acute traumatic Spinal cord injury (TSCI) is a devastating event that causes severe sensory and motor impairments as well as autonomic dysfunction in patients, yet relevant clinical biomarkers have not been established. This study aimed to determine the significance of the serum glucose/potassium ratio (GPR) in evaluating TSCI severity and predicting prognosis. METHODS: An analysis of 520 clinical records of acute TSCI patients from January 2012 to June 2022 was conducted...
November 9, 2023: BMC Musculoskeletal Disorders
#40
REVIEW
Abhiraj D Bhimani, Matthew T Carr, Zahraa Al-Sharshai, Zachary Hickman, Konstantinos Margetis
BACKGROUND: The impact of the timing of surgery on neurological recovery in thoracolumbar spinal cord injuries (tSCI) is still a subject of discussion. Accumulating evidence is supporting early decompression (<24 hours) following tSCI. However, the potential advantages of earlier decompression remain uncertain. This systematic review and meta-analysis summarize and analyze the current evidence on the effectiveness of ultra-early decompression surgery on clinical outcomes following tSCI...
December 2023: N Am Spine Soc J
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