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https://www.readbyqxmd.com/read/28719456/warning-criteria-for-intraoperative-neurophysiologic-monitoring
#1
Quanmeng Liu, Qinzhou Wang, Hongen Liu, William K K Wu, Matthew T V Chan
PURPOSE OF REVIEW: Intraoperative changes in somatosensory (SEP) and motor evoked potentials (MEPs) may indicate potential injury to the spinal cord and will require timely intervention to prevent permanent damage. This review focuses on the validity of currently recommended warning criteria for intraoperative evoked potential monitoring. RECENT FINDINGS: Current guideline recommends a decrease in SEP amplitude by 50% and MEP amplitude by 50-100% as warning signals for injury to the ascending sensory and descending motor pathway, respectively...
July 15, 2017: Current Opinion in Anaesthesiology
https://www.readbyqxmd.com/read/28717173/liquid-phase-sequence-capture-and-targeted-re-sequencing-revealed-novel-polymorphisms-in-tomato-genes-belonging-to-the-mep-carotenoid-pathway
#2
Irma Terracciano, Concita Cantarella, Carlo Fasano, Teodoro Cardi, Giuseppe Mennella, Nunzio D'Agostino
Tomato (Solanum lycopersicum L.) plants are characterized by having a variety of fruit colours that reflect the composition and accumulation of diverse carotenoids in the berries. Carotenoids are extensively studied for their health-promoting effects and this explains the great attention these pigments received by breeders and researchers worldwide. In this work we applied Agilent's SureSelect liquid-phase sequence capture and Illumina targeted re-sequencing of 34 tomato genes belonging to the methylerythritol phosphate (MEP) carotenoid pathway on a panel of 48 genotypes which differ for carotenoid content calculated as the sum of β-carotene, cis- and trans-lycopene...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28715712/propriospinal-cutaneous-induced-emg-suppression-is-unaltered-by-anodal-tdcs-of-healthy-motor-cortex
#3
Alana B McCambridge, James W Stinear, Sarah Peek, Winston D Byblow
OBJECTIVE: Cervical propriospinal premotoneurons (PN) relay descending motor commands and integrate peripheral afferent feedback. Effects of anodal transcranial direct current stimulation (a-tDCS) on propriospinal excitability in the upper limbs are unknown. METHODS: Healthy right-handed adults received a-tDCS or sham tDCS over primary motor cortex (M1) at 1mA (Experiment 1, n=18) or 2mA current intensity (Experiment 2, n=15). Propriospinal excitability was assessed by suppression of background electromyography (EMG) in extensor carpi radialis (ECR) from electrical stimulation of the superficial radial nerve during bilateral (Experiment 1 and 2) or unilateral (Experiment 2 only) activation of the left and/or right ECR...
June 28, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28715240/the-effect-of-inspiratory-muscle-training-on-respiratory-variables-in-a-patient-with-ankylosing-spondylitis-a-case-report
#4
Marlon L Wong, Rachael G Anderson, Kelsey Garcia, Elissa M Housmann, Erin McHale, Gregory S Goldberger, Lawrence P Cahalin
Ankylosing Spondylitis (AS) presents with both musculoskeletal and cardiorespiratory pathophysiological manifestations. Inspiratory muscle training (IMT) may be a useful intervention to address deficits in respiratory and functional status. CASE DESCRIPTION: A 25-year-old male with AS initially sought treatment for low back and right hip pain, but 7 weeks of IMT was also provided due to abnormal respiratory performance. OUTCOMES: At baseline, the patient presented with a resting respiratory rate (RR) of 14...
July 17, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28711850/urinary-phthalate-metabolites-over-the-first-15months-of-life-and-risk-assessment-check-cohort-study
#5
Sunmi Kim, Jangwoo Lee, Jeongim Park, Hai-Joong Kim, Geum Joon Cho, Gun-Ha Kim, So-Hee Eun, Jeong Jae Lee, Gyuyeon Choi, Eunsook Suh, Sooran Choi, Sungjoo Kim, Sung Koo Kim, Young Don Kim, Su Young Kim, Seunghyo Kim, Soyong Eom, Hyo-Bang Moon, Sungkyoon Kim, Kyungho Choi
Phthalates are important group of endocrine disruptors. Infants and young children are susceptible to phthalate exposure. However, information on the phthalate exposure during the early stages of life is very limited. This study was conducted to understand the temporal trend of exposure to major phthalates among infants of Korea during the first 15months after birth, and to estimate associated risks. A total of 286 urine samples were collected from 171 children at 3, 9, 12, or 15months of age, with 77 children sampled for two or more times...
July 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28711600/double-plating-as-treatment-for-supracondylar-humeral-fractures
#6
J Salvador, P Castillón, I Fuentes, M Bernaus, F Anglès
INTRODUCTION AND OBJECTIVES: Supracondylar humeral fractures represent only about 0.5-1% of all fractures in adults. The objective of this study is to evaluate functional outcome and quality of life in patients treated with open reduction and internal fixation using double plates. MATERIAL AND METHODS: We designed a retrospective descriptive study including 27 supracondylar humeral fractures treated with open reduction and internal fixation using two anatomic plates from January 2005 to September 2012...
July 12, 2017: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/28711376/motor-evoked-potentials-in-patients-with-chronic-whiplash-associated-disorder-grade-ii
#7
Jacques De Reuck
BACKGROUND AND PURPOSE: It is common belief that psychological problems influence the persistence of complains in patients with so-called mild whiplash-associated disorders (WADs). The usefulness of motor evoked potentials (MEPs) is investigated in patients with grade II WAD and remaining complains for more than 6 months. PATIENTS AND METHODS: Twenty consecutive patients, aged between 24 and 58 years, with persistent neck pain for months after a car accident were included...
July 8, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28710969/determination-of-urinary-trans-trans-muconic-acid-using-molecularly-imprinted-polymer-in-microextraction-by-packed-sorbent-followed-by-liquid-chromatography-with-ultraviolet-detection
#8
Esmaeel Soleimani, Abdulrahman Bahrami, Abbas Afkhami, Farshid Ghorbani Shahna
trans,trans-Muconic acid (tt-MA) has been introduced as biological exposure index for workers exposed to benzene. In the present study, for the first time, a novel and easy-to-use analytical method based on molecularly imprinted polymer (MIP) in microextraction by packed sorbent (MEPS), followed by high-performance liquid chromatography with ultra-violet detection (MIMEPS-HPLC-UV) was developed to determine tt-MA in urine samples. Fourier transform infrared spectroscopy was used for MIP characterization. The imprinting effect on the MIP was also evaluated...
July 8, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28710663/a-multi-train-electrical-stimulation-protocol-facilitates-transcranial-electrical-motor-evoked-potentials-and-increases-induction-rate-and-reproducibility-even-in-patients-with-preoperative-neurological-deficits
#9
Shuta Ushio, Shigenori Kawabata, Satoshi Sumiya, Tsuyoshi Kato, Toshitaka Yoshii, Tsuyoshi Yamada, Mitsuhiro Enomoto, Atsushi Okawa
This study sought to evaluate the facilitation effect of repetitive multi-train transcranial electrical stimulation (mt-TES) at 2 repetition rates on transcranial electrical motor evoked potential (Tc-MEP) monitoring during spinal surgery, and to assess the induction rate in patients with impaired motor function from a compromised spinal cord or spinal nerve. We studied 32 consecutive patients with impaired motor function undergoing cervical or thoracic spinal surgery (470 muscles). A series of 10 TESs with 5 pulse trains were preoperatively delivered at 2 repetition rates (1 and 5 Hz)...
July 14, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28709092/exposure-to-benzophenones-parabens-and-triclosan-among-pregnant-women-in-different-trimesters
#10
Hongzhi Zhao, Wenqian Huo, Jiufeng Li, Xinli Ma, Wei Xia, Zhengji Pang, Mingyi Xie, Shunqing Xu, Zongwei Cai
Humans are potentially exposed to many environmental pollutants, many of which may cause adverse health effects, especially to pregnant women and their fetuses. In this study, 11 environmental pollutants from three different chemical classes, including benzophenones, parabens and triclosan were measured in 627 urine samples collected from 209 pregnant women to evaluate exposure and trends as a function of pregnancy stage. Methylparaben (MeP), ethylparaben, propylparaben (PrP), butylparaben, 2,4-dihydroxybenzophenone (BP-1), 2-hydroxy-4-methoxybenzophenone (BP-3) and 4-hydroxybenzophenone were detected in >50% samples...
July 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28703352/atpds-over-expression-in-tomato-exposing-unique-patterns-of-carotenoid-self-regulation-and-an-alternative-strategy-for-the-enhancement-of-fruit-carotenoid-content
#11
Ryan P McQuinn, Breanna Wong, James J Giovannoni
The regulation of plant carotenogenesis is an active research area for both biological discovery and practical implementation. In tomato (Solanum lycopersicum) we demonstrate additional bottlenecks exist in the poly-cis-transformation of phytoene to lycopene in the context of ripening-induced PSY1 expression and activity, and reveal phytoene desaturase (PDS), as a target for manipulation toward elevated lycopene content in maturing tomato fruit. Over-expression of Arabidopsis PDS, AtPDS, elevated PDS transcript abundance in all aerial tissues resulting in both altered carotenoid accumulation and associated pathway gene expression in a tissue-specific manner...
July 13, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28702865/public-health-insurance-and-health-care-utilization-for-children-in-immigrant-families
#12
Christine Percheski, Sharon Bzostek
Objectives To estimate the impacts of public health insurance coverage on health care utilization and unmet health care needs for children in immigrant families. Methods We use survey data from National Health Interview Survey (NHIS) (2001-2005) linked to data from Medical Expenditures Panel Survey (MEPS) (2003-2007) for children with siblings in families headed by at least one immigrant parent. We use logit models with family fixed effects. Results Compared to their siblings with public insurance, uninsured children in immigrant families have higher odds of having no usual source of care, having no health care visits in a 2 year period, having high Emergency Department reliance, and having unmet health care needs...
July 12, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28701544/modulation-of-corticospinal-input-to-the-legs-by-arm-and-leg-cycling-in-people-with-incomplete-spinal-cord-injury
#13
Rui Zhou, Laura Alvarado, Seoyoung Kim, Su Ling Chong, Vivian K Mushahwar
The spinal cervico-lumbar interaction during rhythmic movements in humans has recently been studied; however, the role of arm movements in modulating the corticospinal drive to the legs is not well understood. The goals of this study were to investigate the effect of active rhythmic arm movements on the corticospinal drive to the legs (study 1); and assess the effect of simultaneous arm and leg training on the corticospinal pathway after incomplete spinal cord injury (iSCI) (study 2). In study 1, neurologically intact (NI) participants or participants with iSCI performed combinations of stationary and rhythmic cycling of the arms and legs, while motor evoked potentials (MEPs) were recorded from the vastus lateralis (VL) muscle...
July 12, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28697389/interaction-patterns-and-toxicities-of-binary-and-ternary-pesticide-mixtures-to-daphnia-magna-estimated-by-an-accelerated-failure-time-model
#14
Xuchun Qiu, Wataru Tanoue, Atsushi Kawaguchi, Takashi Yanagawa, Masanori Seki, Yohei Shimasaki, Tsuneo Honjo, Yuji Oshima
Organisms in natural environments are often exposed to a broad variety of chemicals, and the multi-chemical mixtures exposure may produce significant toxic effects, even though the individual chemicals are present at concentrations below their no-observed-effect concentrations. This study represents the first attempt that uses the accelerated failure time (AFT) model to quantify the interaction and toxicity of multi-chemical mixtures in environmental toxicology. We firstly conducted the acute immobilization tests with Daphnia magna exposed to mixtures of diazinon (DZN), fenitrothion (MEP); and thiobencarb (TB) in single, binary, and ternary formulations, and then fitted the results to the AFT model...
July 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28694266/comparing-medical-ecology-utilization-and-expenditures-between-1996-1997-and-2011-2012
#15
Michael E Johansen
PURPOSE: This study compared ecology (number of individuals using a service), utilization (number of services used), and expenditures (dollars spent) for various categories of medical services between primarily 1996-1997 and 2011-2012. METHODS: A repeated cross-sectional study was performed using nationally representative data mainly from the 1996, 1997, 2011, and 2012 Medical Expenditure Panel Survey (MEPS). These data were augmented with the 2002-2003 MEPS as well as the 1999-2000 and 2011-2012 National Heath and Nutrition Examination Survey...
July 2017: Annals of Family Medicine
https://www.readbyqxmd.com/read/28694153/caffeinated-energy-drink-intake-modulates-motor-circuits-at-rest-before-and-after-a-movement
#16
Carmen Concerto, Carmenrita Infortuna, Eileen Chusid, Diego Coira, Jacqueline Babayev, Rowan Metwaly, Hesam Naenifard, Eugenio Aguglia, Fortunato Battaglia
Energy drinks are thought to improve certain aspects of athletic and cognitive performances. Moreover, less is understood about physiological mechanisms that might underlie these effects. The aim of this study was to examine the influence of sugar-free energy drink (SFED) ingestion on corticomotor excitability and plasticity. Fourteen college students consumed a commercially available SFED or a "dummy" drink. By using Transcranial magnetic Stimulation (TMS) we investigated resting motor threshold (RMT), motor evoked potential (MEP) amplitude and cortical silent period (CSP)...
July 8, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28691588/the-relation-between-the-motor-evoked-potential-and-diffusion-tensor-tractography-for-the-corticospinal-tract-in-chronic-hemiparetic-patients-with-cerebral-infarct
#17
Sung Ho Jang, Dea Hee Kim, Seong Ho Kim, Jeong Pyo Seo
We examined the relation between the results of transcranial magnetic stimulation (TMS) and diffusion tensor tractography (DTT) for the corticospinal tract (CST) in chronic hemiparetic patients with a middle cerebral artery (MCA) territory infarct. The amplitude of motor evoked potential (MEP) was closely related to the FN of the CST on DTT in chronic hemiparetic patients with an MCA infarct. We believe that our results would be helpful in more precise estimation of the CST.
July 9, 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/28688846/evaluation-of-nitrate-effects-in-the-aqueous-photodegradability-of-selected-phenolic-pollutants
#18
G Castro, I Rodríguez, M Ramil, R Cela
The effect of nitrate in the aqueous photodegradation of five phenolic environmental pollutants (ortho-phenylphenol, OPP; methyl paraben, MeP; propyl paraben, PrP; Triclosan, TCS and bisphenol A, BPA) is evaluated. Time-course of precursor compounds and formation of transformation products (TPs) were investigated by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS). Nitrate showed a positive effect in the removal of selected pollutants. Observed TPs resulted from hydroxylation, aromatic nitration (with or without molecule cleavage) and nitro dehalogenation processes...
July 3, 2017: Chemosphere
https://www.readbyqxmd.com/read/28687954/cortical-voluntary-activation-testing-methodology-impacts-central-fatigue
#19
José Mira, Thomas Lapole, Robin Souron, Laurent Messonnier, Guillaume Y Millet, Thomas Rupp
PURPOSE: Currently, cortical voluntary activation (VATMS) is assessed by superimposing transcranial magnetic stimulation (TMS) on a maximal voluntary contraction (MVC), 75% MVC and 50% MVC, each contraction being interspersed with 5-10 s of relaxation. Here, we assessed whether this traditional approach (TRADI) underestimates central fatigue due to this short recovery compared to a continuous method (CONTI). METHODS: VATMS, motor-evoked potential (MEP), and cortical silent period (CSP) of the vastus lateralis were determined in 12 young healthy adults before and after a 2-min sustained MVC of knee extensors in two randomly assigned sessions...
July 7, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28682009/the-road-map-for-megakaryopoietic-lineage-from-hematopoietic-stem-progenitor-cells
#20
EDITORIAL
Hidekazu Nishikii, Naoki Kurita, Shigeru Chiba
Megakaryocytes (Mgks) are terminally differentiated blood cells specified to produce platelets, whereas hematopoietic stem cells (HSCs) are the most undifferentiated blood cells that retain multipotency to produce all kinds of blood cells. As such, these two cell types reside at the bottom and the top of the hematopoietic hierarchy, respectively. In spite of this distance, they share several important cell surface molecules as well as transcription factors. In the conventional step-wise differentiation model, HSCs gradually lose their self-renewal capacity and differentiate into multipotent progenitors (MPPs), which is the first branch point of myeloid and lymphoid lineage...
July 6, 2017: Stem Cells Translational Medicine
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