keyword
MENU ▼
Read by QxMD icon Read
search

Skin adhesive

keyword
https://www.readbyqxmd.com/read/28334263/pathogenesis-of-meningococcal-purpura-fulminans
#1
H Lécuyer, D Borgel, X Nassif, M Coureuil
Purpura fulminans (PF) is a dreadful and frequent complication of Neisseria meningitidis invasive infection, and is associated with a high mortality rate. This syndrome begins with dermal microvessels thrombosis that rapidly lead to hemorrhagic skin necrosis. In this review, we discuss the prothrombotic events occurring during meningococcal infection. Moreover, recent data from an experimental mouse model have highlighted the critical role of the meningococcus adhesion to the endothelium in the development of PF lesions, thus opening new therapeutic perspectives...
March 9, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28332498/a-genome-wide-screen-identifies-yap-wbp2-interplay-conferring-growth-advantage-on-human-epidermal-stem-cells
#2
Gernot Walko, Samuel Woodhouse, Angela Oliveira Pisco, Emanuel Rognoni, Kifayathullah Liakath-Ali, Beate M Lichtenberger, Ajay Mishra, Stephanie B Telerman, Priyalakshmi Viswanathan, Meike Logtenberg, Lisa M Renz, Giacomo Donati, Sven R Quist, Fiona M Watt
Individual human epidermal cells differ in their self-renewal ability. To uncover the molecular basis for this heterogeneity, we performed genome-wide pooled RNA interference screens and identified genes conferring a clonal growth advantage on normal and neoplastic (cutaneous squamous cell carcinoma, cSCC) human epidermal cells. The Hippo effector YAP was amongst the top positive growth regulators in both screens. By integrating the Hippo network interactome with our data sets, we identify WW-binding protein 2 (WBP2) as an important co-factor of YAP that enhances YAP/TEAD-mediated gene transcription...
March 23, 2017: Nature Communications
https://www.readbyqxmd.com/read/28325766/staphylococcal-%C3%AE-toxin-modulates-human-aortic-endothelial-cell-and-platelet-function-through-sphingomyelinase-and-biofilm-ligase-activities
#3
Alfa Herrera, Katarina Kulhankova, Vijay K Sonkar, Sanjana Dayal, Aloysius J Klingelhutz, Wilmara Salgado-Pabón, Patrick M Schlievert
Staphylococcus aureus causes many infections, such as skin and soft tissue, pneumonia, osteomyelitis, and infective endocarditis (IE). IE is an endovascular infection of native and prosthetic valves and the lining of the heart; it is characterized by the formation of cauliflower-like "vegetations" composed of fibrin, platelets, other host factors, bacteria, and bacterial products. β-Toxin is an S. aureus virulence factor that contributes to the microorganism's ability to cause IE. This cytolysin has two enzymatic activities: sphingomyelinase (SMase) and biofilm ligase...
March 21, 2017: MBio
https://www.readbyqxmd.com/read/28320969/ena-vasp-proteins-regulate-activated-t-cell-trafficking-by-promoting-diapedesis-during-transendothelial-migration
#4
Miriam L Estin, Scott B Thompson, Brianna Traxinger, Marlie H Fisher, Rachel S Friedman, Jordan Jacobelli
Vasodilator-stimulated phosphoprotein (VASP) and Ena-VASP-like (EVL) are cytoskeletal effector proteins implicated in regulating cell morphology, adhesion, and migration in various cell types. However, the role of these proteins in T-cell motility, adhesion, and in vivo trafficking remains poorly understood. This study identifies a specific role for EVL and VASP in T-cell diapedesis and trafficking. We demonstrate that EVL and VASP are selectively required for activated T-cell trafficking but are not required for normal T-cell development or for naïve T-cell trafficking to lymph nodes and spleen...
March 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28314902/potential-factors-enabling-human-body-colonization-by-animal-streptococcus-dysgalactiae-subsp-equisimilis-strains
#5
Marcin Ciszewski, Eligia M Szewczyk
Streptococcus dysgalactiae subsp. equisimilis (SDSE) is a pyogenic, Lancefield C or G streptococcal pathogen. Until recently, it has been considered as an exclusive animal pathogen. Nowadays, it is responsible for both animal infections in wild animals, pets, and livestock and human infections often clinically similar to the ones caused by group A streptococcus (Streptococcus pyogenes). The risk of zoonotic infection is the most significant in people having regular contact with animals, such as veterinarians, cattlemen, and farmers...
March 18, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28314701/genitourinary-involvement-and-management-in-children-with-stevens-johnson-syndrome-and-toxic-epidermal-necrolysis
#6
J P Van Batavia, D I Chu, C J Long, M Jen, D A Canning, D A Weiss
BACKGROUND: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are devastating hypersensitivity disorders that cause epidermal cell death and can affect all epidermal surfaces, including the urethra, vagina, labial and scrotal skin. Despite the well-described ocular and orofacial manifestations of SJS/TEN, there is a paucity of reports on the genitourinary (GU) symptoms and their management. Specifically, consulting services often ask the pediatric urology team if it is safe to place a urethral catheter, but there is no data in the literature to help guide management...
February 27, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28293518/the-use-of-a-hyaluronic-acid-carboxymethylcellulose-membrane-as-an-adhesion-barrier-during-nipple-delay-before-nipple-preserving-mastectomy
#7
Andreas M Lamelas, Eric M Jablonka, Marco A Harmaty, Philip J Torina
The desire for nipple-preserving mastectomies has increased over the past decade as studies have proven that the procedure has comparable oncologic risk as a traditional mastectomy in both therapeutic and prophylactic cases. Partial or complete nipple necrosis is a well-known complication of this procedure with rates in the literature ranging between 1% and 9%. In high-risk patients, surgeons are performing a delay procedure before the mastectomy to help improve nipple vascularity and decrease necrosis rates...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28293103/protective-influence-of-hyaluronic-acid-on-focal-adhesion-kinase-activity-in-human-skin-fibroblasts-exposed-to-ethanol
#8
Magdalena Donejko, Edyta Rysiak, Elżbieta Galicka, Robert Terlikowski, Edyta Katarzyna Głażewska, Andrzej Przylipiak
AIM: The aim of this study was to evaluate the effect of ethanol and hyaluronic acid (HA) on cell survival and apoptosis in cultured human skin fibroblasts. Regarding the mechanism of ethanol action on human skin fibroblasts, we investigated cell viability and apoptosis, expression of focal adhesion kinase (FAK), and the influence of HA on those processes. MATERIALS AND METHODS: Studies were conducted in confluent human skin fibroblast cultures that were treated with 25 mM, 50 mM, and 100 mM ethanol or with ethanol and 500 µg/mL HA...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28290610/kindlin-1-contributes-to-egf-induced-re-epithelialization-in-skin-wound-healing
#9
Congcong Shen, Linlin Sun, Ningwen Zhu, Fazhi Qi
The commercial use of epidermal growth factor (EGF) is extensive and has been shown to be effective for skin wound healing in clinical practice. There is evidence to indicate that the topical administration of EGF significantly accelerates re-epithelialization by promoting keratinocyte mitogenesis and migration following acute injury; however, the mechanisms involved remain to be elucidated. Thus, in this study, we focused on Kindlin-1, a four-point-one, ezrin, radixin, moesin (FERM)-domain-containing adaptor protein, and report its contribution to EGF-induced re-epithelialization in skin wound healing...
March 7, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28277990/preventing-facial-pressure-ulcers-in-patients-under-non-invasive-mechanical-ventilation-a-randomised-control-trial
#10
D Peña Otero, D Vazquez Domínguez, L Hernanz Fernández, A Santano Magariño, V Jimenez González, J V García Klepzing, J V Beneit Montesinos
OBJECTIVE: To comparatively assess the efficacy of four different therapeutic strategies to prevent the development of facial pressure ulcers (FPUs) related to the use of non-invasive mechanical ventilation (NIV) with oro-nasal masks in critically ill hospitalised patients. METHOD: This randomised control trial was performed at the high dependency unit in the University General Hospital Gregorio Marañón in Madrid, Spain. Overall, 152 patients with acute respiratory failure were recruited...
March 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28277010/in-vitro-and-in-vivo-evaluation-of-the-chitosan-tur-composite-film-for-wound-healing-applications
#11
Qin Zou, Bin Cai, Junfeng Li, Jidong Li, Yubao Li
We have developed tourmaline/chitosan (Tur/CS) composite films for wound healing applications. The characteristics of composite films were studied by optical microscope, infrared spectra and X-ray diffraction. Tur particles were uniformly distributed in the CS film and the crystal structure of CS was not remarkably changed except the decrease of crystallinity. The influence of Tur on wound healing applications was characterized by modulating Tur concentrations in the Tur/CS composite film prepared by loading Tur powder into CS matrix with different proportion (0, 1/40 and 1/10)...
May 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28274741/a-systemic-evaluation-of-drug-in-acrylic-pressure-sensitive-adhesive-patch-in-vitro-and-in-vivo-the-roles-of-intermolecular-interaction-and-adhesive-mobility-variation-in-drug-controlled-release
#12
Chao Liu, Peng Quan, Shanshan Li, Yongshan Zhao, Liang Fang
Though acrylic pressure sensitive adhesives (PSAs) are widely used in transdermal drug delivery system, molecular details of drug-PSA interactions, PSA molecular mobility variations and their influences on drug skin permeation are unclear. In this study, three classes of acrylic PSAs containing hydroxyl (AAOH), carboxyl (AACOOH) and non-functional group (AAnone) were synthesized. Their abilities of controlling drug release were evaluated using propranolol (PRO) and zaltoprofen (ZAL) in vitro and in vivo. Interaction details were identified by FT-IR, solid-state NMR and molecular modeling...
March 6, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28269549/novel-dry-electrodes-for-recording-electrodermal-activity
#13
Hugo F Posada-Quintero, Ryan Rood, Yeonsik Noh, Ken Burnham, John Pennace, Ki H Chon
Novel carbon/salt adhesive (CSA) electrodes have been found suitable for collecting electrodermal activity (EDA) signals. Ag/AgCl electrodes are considered the standard for collecting EDA signals, because it highly avoids electrodes' polarization. Ag is an expensive commodity. Furthermore, a hydrogel layer is needed for the Ag/AgCl electrodes to collect EDA signals. Adding hydrogel to the electrodes is a cumbersome process. Aforementioned circumstances highlight the need for a more accessible media to collect these signals, allowing EDA use to spread...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267128/medical-adhesive-related-skin-injury-following-emergent-appendectomy-a-case-study-of-marsi-and-missed-opportunities-in-nursing-care
#14
Sylvia E Britt, Karen M Coles, Shannon S Polson
BACKGROUND: The potential for skin damage from adhesive products is documented in the literature. Nevertheless, health care providers continue to lack understanding of the impact and seriousness of skin injury associated with use of tapes or other adhesive devices when applied to a patient with a history or hypersensitivity or allergy to adhesives. CASE: A 67-year-old woman with a history of tape allergy underwent emergency appendectomy. Initial removal of an adhesive bandage placed over the surgical incision revealed medical adhesive-related skin injury (MARSI)...
March 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28259957/photodynamic-inactivation-of-fibroblasts-and-inhibition-of-staphylococcus%C3%A2-epidermidis-adhesion-and-biofilm-formation-by-toluidine-blue-o
#15
Xin Li, Zizhong Liu, Houfang Liu, Xi Chen, Yue Liu, Honglue Tan
Treating skin and soft tissue infections of severe limb traumas can be challenging. Crucial concerns focus on inhibiting biofilm formation by antibiotic‑resistant bacteria, and preventing scar formation by fibroblastic hyperproliferation. The local use of toluidine blue O (TBO)‑mediated photodynamic therapy (PDT) may be a promising strategy for treating such lesions. The present study used Staphylococcus epidermidis (strain ATCC 35984) to assess the effects of TBO‑PDT on bacterial adherence and biofilm formation, using confocal laser scanning microscopy (CLSM), tissue culture plating (TCP) and scanning electron microscopy (SEM)...
February 8, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28259757/comprehensive-characteristics-of-microrna-expression-profile-of-equine-sarcoids
#16
Klaudia Pawlina, Artur Gurgul, Tomasz Szmatoła, Christoph Koch, Kathrin Mählmann, Maciej Witkowski, Monika Bugno-Poniewierska
Equine sarcoids are the most common neoplasms occurring in horses. Despite frequent occurrence, they are still not well described at the molecular level. Thus, in the present study, we performed a comprehensive comparative analysis of sarcoid miRNAome profile to identify aberrantly expressed microRNAs, along with their structural variants, potentially useful as biomarkers and, in a wider perspective, broaden the knowledge about this tumor and underlying mechanisms. To this end, we conducted next generation sequencing and as a result we identified both known and potentially novel miRNAs...
March 1, 2017: Biochimie
https://www.readbyqxmd.com/read/28254297/a-novel-chitosan-hydrogel-membrane-by-an-improved-electrophoretic-deposition-and-its-characteristics-in-vitro-and-in-vivo
#17
Wen-Wen Li, Hai-Yan Wang, Yu-Qing Zhang
Here, we report a novel chitosan hydrogel membrane (CHM) created by an improved electrophoretic deposition. Unlike a traditional CHM by electrophoretic deposition, the CHM was formed on a nanoporous film as a barrier using a homemade device at a high DC voltage (60 VDC). The CHM maximum recovery of 81.7% could be achieved after 1h of electrophoretic deposition. The transparent CHM with an elongation of 42.46% and swelling index of 538.86% was a mixture of type I and type II crystal structures. SEM revealed that the CHM had an irregular net structure...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28245107/mussel-inspired-adhesive-and-tough-hydrogel-based-on-nanoclay-confined-dopamine-polymerization
#18
Lu Han, Xiong Lu, Kezhi Liu, Kefeng Wang, Liming Fang, Lu-Tao Weng, Hongping Zhang, Youhong Tang, Fuzeng Ren, Cancan Zhao, Guoxing Sun, Rui Liang, Zongjin Li
Adhesive hydrogels are attractive biomaterials for various applications, such as electronic skin, wound dressing, and wearable devices. However, fabricating a hydrogel with both adequate adhesiveness and excellent mechanical properties remains a challenge. Inspired by the adhesion mechanism of mussels, we used a two-step process to develop an adhesive and tough polydopamine-clay-polyacrylamide (PDA-clay-PAM) hydrogel. Dopamine was intercalated into clay nanosheets and limitedly oxidized between the layers, resulting in PDA-intercalated clay nanosheets containing free catechol groups...
March 6, 2017: ACS Nano
https://www.readbyqxmd.com/read/28238662/coordination-by-cdc42-of-actin-contractility-and-adhesion-for-melanoblast-movement-in-mouse-skin
#19
Emma F Woodham, Nikki R Paul, Benjamin Tyrrell, Heather J Spence, Karthic Swaminathan, Michelle R Scribner, Evangelos Giampazolias, Ann Hedley, William Clark, Frieda Kage, Daniel J Marston, Klaus M Hahn, Stephen W G Tait, Lionel Larue, Cord H Brakebusch, Robert H Insall, Laura M Machesky
The individual molecular pathways downstream of Cdc42, Rac, and Rho GTPases are well documented, but we know surprisingly little about how these pathways are coordinated when cells move in a complex environment in vivo. In the developing embryo, melanoblasts originating from the neural crest must traverse the dermis to reach the epidermis of the skin and hair follicles. We previously established that Rac1 signals via Scar/WAVE and Arp2/3 to effect pseudopod extension and migration of melanoblasts in skin...
March 6, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28238313/-laparoscopic-lateral-suspension-another-way-to-treat-genital-prolapse
#20
J B Dubuisson, N Veit-Rubin, J M Wenger, J Dubuisson
The laparoscopic sacrocolpopexy is the treatment of choice of pelvic organ prolapses since more than twenty years. The laparoscopic lateral suspension with mesh is an alternative technique. Its originality is the subperitoneal passing of the lateral arm of the mesh in the lateral abdominal wall, leaving the skin above the iliac crest, in a place without risks of vascular, nerve, bowel injuries. We report in this article the results of the three main publications on the subject. The indications are cystocele and apical descent...
January 2017: Gynecol Obstet Fertil Senol
keyword
keyword
107447
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"