keyword
MENU ▼
Read by QxMD icon Read
search

Chest CT for screening for lung cancer

keyword
https://www.readbyqxmd.com/read/29468601/patient-and-clinician-perspectives-on-shared-decision-making-in-early-adopting-lung-cancer-screening-programs-a-qualitative-study
#1
Renda Soylemez Wiener, Elisa Koppelman, Rendelle Bolton, Karen E Lasser, Belinda Borrelli, David H Au, Christopher G Slatore, Jack A Clark, Hasmeena Kathuria
BACKGROUND: Guidelines recommend, and Medicare requires, shared decision-making between patients and clinicians before referring individuals at high risk of lung cancer for chest CT screening. However, little is known about the extent to which shared decision-making about lung cancer screening is achieved in real-world settings. OBJECTIVE: To characterize patient and clinician impressions of early experiences with communication and decision-making about lung cancer screening and perceived barriers to achieving shared decision-making...
February 21, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29464877/patient-navigation-for-lung-cancer-screening-among-current-smokers-in-community-health-centers-a-randomized-controlled-trial
#2
Sanja Percac-Lima, Jeffrey M Ashburner, Nancy A Rigotti, Elyse R Park, Yuchiao Chang, Salome Kuchukhidze, Steven J Atlas
Annual chest computed tomography (CT) can decrease lung cancer mortality in high-risk individuals. Patient navigation improves cancer screening rates in underserved populations. Randomized controlled trial was conducted from February 2016 to January 2017 to evaluate the impact of a patient navigation program on lung cancer screening (LCS) among current smokers in five community health centers (CHCs) affiliated with an academic primary care network. We randomized 1200 smokers aged 55-77 years to intervention (n = 400) or usual care (n = 800)...
February 21, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29452098/features-of-chronic-obstructive-pulmonary-disease-as-predictors-of-lung-cancer
#3
Laurie L Carr, Sean Jacobson, David A Lynch, Marilyn G Foreman, Eric L Flenaugh, Craig P Hersh, Frank C Sciurba, David O Wilson, Jessica C Sieren, Patrick Mulhall, Victor Kim, C Matthew Kinsey, Russell P Bowler
BACKGROUND: Lung cancer is a leading cause of death and hospitalization for patients with chronic obstructive lung disease, (COPD); a detailed understanding of which clinical features of COPD increase risk is needed. METHODS: To identify clinical and imaging features of smokers, with and without COPD, that are associated with an increased risk of lung cancer, we performed a nested case-control study of COPDGene subjects with and without lung cancer, age 45-80, who smoked at least 10-pack years...
February 13, 2018: Chest
https://www.readbyqxmd.com/read/29412152/development-and-validation-of-a-novel-diagnostic-nomogram-model-based-on-tumor-markers-for-assessing-cancer-risk-of-pulmonary-lesions-a-multicenter-study-in-chinese-population
#4
Qiang Du, Cunling Yan, San-Gang Wu, Wei Zhang, Chun Huang, Yiyong Yao, Liyu Wang, Qunji Zhang, Qinghao Liu, Jie Guang, Yanfeng Hou, Zhiyan Li, Andrew Soh, Agim Beshiri, Qi Wang, Xun Li, Yijie Zheng, Huiling Wang
PURPOSE: This study aimed to build a valid diagnostic nomogram for assessing the cancer risk of the pulmonary lesions identified by chest CT. PATIENTS AND METHODS: A total of 691 patients with pulmonary lesions were recruited from three centers in China. The cut-off value for each tumor marker was confirmed by minimum P value method with 1000 bootstrap replications. The nomogram was based on the predictive factors identified by univariate and multivariate analysis...
February 2, 2018: Cancer Letters
https://www.readbyqxmd.com/read/29408789/automatic-calcium-scoring-in-low-dose-chest-ct-using-deep-neural-networks-with-dilated-convolutions
#5
Nikolas Lessmann, Bram van Ginneken, Majd Zreik, Pim A de Jong, Bob D de Vos, Max A Viergever, Ivana Isgum
Heavy smokers undergoing screening with low-dose chest CT are affected by cardiovascular disease as much as by lung cancer. Low-dose chest CT scans acquired in screening enable quantification of atherosclerotic calcifications and thus enable identification of subjects at increased cardiovascular risk. This paper presents a method for automatic detection of coronary artery, thoracic aorta, and cardiac valve calcifications in low-dose chest CT using two consecutive convolutional neural networks. The first network identifies and labels potential calcifications according to their anatomical location and the second network identifies true calcifications among the detected candidates...
February 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/29394804/-a-case-of-synchronous-quadruple-cancers-treated-with-neoadjuvant-chemotherapy-followed-by-surgery
#6
Keiji Muramoto, Toru Miyake, Tomoharu Shimizu, Hiromichi Sonoda, Tomoyuki Ueki, Yoshitaka Terada, Haruki Mori, Hiromitsu Maehira, Katsushi Takebayashi, Sachiko Kaida, Hiroya Iida, Tsuyoshi Yamaguchi, Masaji Tani
The patient is male in his 60's. He underwent endoscopic examination for anemia, which was found during screening of high PSA value. Endoscopic examination revealed a gastric cancer and 3 colorectal cancers. Histological results from biopsy was HER2 positive poorly differentiated adenocarcinoma in gastric tumor and moderately differentiated adenocarcinoma in colorectal tumor. Chest CT showed a pulmonary nodule in the middle right lung. Histological diagnosis was TTF-1 positive adenocarcinoma, meaning primary lung cancer...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29375824/early-detection-and-chemoprevention-of-lung-cancer
#7
REVIEW
Melissa New, Robert Keith
Despite advances in targeted treatments, lung cancer remains a common and deadly malignancy, in part owing to its typical late presentation. Recent developments in lung cancer screening and ongoing efforts aimed at early detection, treatment, and prevention are promising areas to impact the mortality from lung cancer. In the past several years, lung cancer screening with low-dose chest computed tomography (CT) was shown to have mortality benefit, and lung cancer screening programs have been implemented in some clinical settings...
2018: F1000Research
https://www.readbyqxmd.com/read/29374513/screening-for-lung-cancer-chest-guideline-and-expert-panel-report
#8
Peter J Mazzone, Gerard A Silvestri, Sheena Patel, Jeffrey P Kanne, Linda S Kinsinger, Renda Soylemez Wiener, Guy Soo Hoo, Frank C Detterbeck
BACKGROUND: Low-dose chest CT screening for lung cancer has become a standard of care in the United States in the past few years, in large part due to the results of the National Lung Screening Trial. The benefit and harms of low-dose chest CT screening differ in both frequency and magnitude. The translation of a favorable balance of benefit and harms into practice can be difficult. Here, we update the evidence base for the benefit, harms, and implementation of low radiation dose chest CT screening...
January 24, 2018: Chest
https://www.readbyqxmd.com/read/29356386/significance-of-tumor-associated-autoantibodies-in-the-early-diagnosis-of-lung-cancer
#9
Qiang Du, Ruofei Yu, Han Wang, Dong Yan, Qi Yuan, Yixin Ma, Dennis Slamon, Dongmei Hou, Huiling Wang, Qi Wang
OBJECTIVES: Autoantibodies tumor-associated antigens (TAAs) could be a valuable tool for the diagnosis or early detection of cancer due to their relatively high specificity and stability. The purpose of this study is to detect the level of tumor-associated autoantibodies in lung cancer and assess the diagnostic potential of autoantibodies in screening strategy for early stage lung cancer. MATERIALS AND METHODS: Levels of tumor-associated autoantibodies (AAbs) were measured against a panel of seven tumor-associated antigens (p53, PGP9...
January 22, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29343293/identification-of-preoperative-prediction-factors-of-tumor-subtypes-for-patients-with-solitary-ground-glass-opacity-pulmonary-nodules
#10
Meishuang Li, Yanan Wang, Yulong Chen, Zhenfa Zhang
BACKGROUND: Recent wide spread use of low-dose helical computed tomography for the screening of lung cancer have led to an increase in the detection rate of very faint and smaller lesions known as ground-glass opacity nodules. The purpose of this study was to investigate the clinical factors of lung cancer patients with solitary ground-glass opacity pulmonary nodules on computed tomography. METHODS: A total of 423 resected solitary ground-glass opacity nodules were retrospectively evaluated...
January 17, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29290259/radiomics-and-radiogenomics-in-lung-cancer-a-review-for-the-clinician
#11
REVIEW
Rajat Thawani, Michael McLane, Niha Beig, Soumya Ghose, Prateek Prasanna, Vamsidhar Velcheti, Anant Madabhushi
Lung cancer is responsible for a large proportion of cancer-related deaths across the globe, with delayed detection being perhaps the most significant factor for its high mortality rate. Though the National Lung Screening Trial argues for screening of certain at-risk populations, the practical implementation of these screening efforts has not yet been successful and remains in high demand. Radiomics refers to the computerized extraction of data from radiologic images, and provides unique potential for making lung cancer screening more rapid and accurate using machine learning algorithms...
January 2018: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29282271/circulating-tumour-cells-as-a-potential-screening-tool-for-lung-cancer-the-air-study-protocol-of-a-prospective-multicentre-cohort-study-in-france
#12
Sylvie Leroy, Jonathan Benzaquen, Andrea Mazzetta, Sylvain Marchand-Adam, Bernard Padovani, Dominique Israel-Biet, Christophe Pison, Pascal Chanez, Jacques Cadranel, Julien Mazières, Vincent Jounieaux, Charlotte Cohen, Véronique Hofman, Marius Ilie, Paul Hofman, Charles Hugo Marquette
INTRODUCTION: Lung cancer (LC) is the leading cause of death from cancer. Early diagnosis of LC is of paramount importance in terms of prognosis. The health authorities of most countries do not accept screening programmes based on low-dose chest CT (LDCT), especially in Europe, because they are flawed by a high rate of false-positive results, leading to a large number of invasive diagnostic procedures. These authorities advocated further research, including companion biological tests that could enhance the effectiveness of LC screening...
December 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/29239005/automated-image-quality-assessment-for-chest-ct-scans
#13
Anthony P Reeves, Yiting Xie, Shuang Liu
PURPOSE: Medical image quality needs to be maintained at standards sufficient for effective clinical reading. Automated computer analytic methods may be applied to medical images for quality assessment. METHODS: For chest CT scans in a lung cancer screening context, an automated quality assessment method is presented that characterizes image noise and image intensity calibration. This is achieved by image measurements in three automatically segmented homogeneous regions of the scan: external air, trachea lumen air, and descending aorta blood...
December 14, 2017: Medical Physics
https://www.readbyqxmd.com/read/29231759/screening-for-lung-cancer-incidental-pulmonary-parenchymal-findings
#14
Jonathan H Chung, J Caleb Richards, Tilman L Koelsch, Heber MacMahon, David A Lynch
OBJECTIVE: Incidental pulmonary findings are commonly detected at lung cancer screening chest CT. Though most of these findings are clinically insignificant, it is difficult to prospectively determine which are potentially important to clinical care. The purpose of this review is to discuss the incidental pulmonary findings commonly detected at lung cancer screening chest CT. CONCLUSION: Incidental pulmonary findings most commonly fall into one of three categories: interstitial lung disease, emphysema, and airways disease (both small and large airways)...
December 12, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29191603/serum-lipid-profile-discriminates-patients-with-early-lung-cancer-from-healthy-controls
#15
Małgorzata Ros-Mazurczyk, Karol Jelonek, Michał Marczyk, Franciszek Binczyk, Monika Pietrowska, Joanna Polanska, Rafał Dziadziuszko, Jacek Jassem, Witold Rzyman, Piotr Widlak
OBJECTIVES: The role of a low-dose computed tomography lung cancer screening remains a matter of controversy due to its low specificity and high costs. Screening complementation with blood-based biomarkers may allow a more efficient pre-selection of candidates for imaging tests or discrimination between benign and malignant chest abnormalities detected by low-dose computed tomography (LD-CT). We searched for a molecular signature based on a serum lipid profile distinguishing individuals with early lung cancer from healthy participants of the lung cancer screening program...
October 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29181428/pulmonary-nodule-classification-in-lung-cancer-screening-with-three-dimensional-convolutional-neural-networks
#16
Shuang Liu, Yiting Xie, Artit Jirapatnakul, Anthony P Reeves
A three-dimensional (3-D) convolutional neural network (CNN) trained from scratch is presented for the classification of pulmonary nodule malignancy from low-dose chest CT scans. Recent approval of lung cancer screening in the United States provides motivation for determining the likelihood of malignancy of pulmonary nodules from the initial CT scan finding to minimize the number of follow-up actions. Classifier ensembles of different combinations of the 3-D CNN and traditional machine learning models based on handcrafted 3-D image features are also explored...
October 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/29173759/early-detection-of-lung-cancer-using-ultra-low-dose-computed-tomography-in-coronary-ct-angiography-scans-among-patients-with-suspected-coronary-heart-disease
#17
Matheus Zanon, Gabriel Sartori Pacini, Vinicius Valério Silveiro de Souza, Edson Marchiori, Gustavo Souza Portes Meirelles, Gilberto Szarf, Felipe Soares Torres, Bruno Hochhegger
OBJECTIVES: To assess whether an additional chest ultra-low-dose CT scan to the coronary CT angiography protocol can be used for lung cancer screening among patients with suspected coronary artery disease. METHODS: 175 patients underwent coronary CT angiography for assessment of coronary artery disease, additionally undergoing ultra-low-dose CT screening to early diagnosis of lung cancer in the same scanner (80kVp and 15mAs). Patients presenting pulmonary nodules were followed-up for two years, repeating low-dose CTs in intervals of 3, 6, or 12 months based on nodule size and growth rate in accordance with National Comprehensive Cancer Network guidelines...
December 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/29154123/3d-skeletonization-feature-based-computer-aided-detection-system-for-pulmonary-nodules-in-ct-datasets
#18
Weihang Zhang, Xue Wang, Xuanping Li, Junfeng Chen
Pulmonary nodule detection has a significant impact on early diagnosis of lung cancer. To effectively detect pulmonary nodules from interferential vessels in chest CT datasets, this paper proposes a novel 3D skeletonization feature, named as voxels remove rate. Based on this feature, a computer-aided detection system is constructed to validate its performance. The system mainly consists of five stages. Firstly, the lung tissues are segmented by a global optimal active contour model, which can extract all structures (including juxta-pleural nodules) in the lung region...
November 11, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29121063/malignancy-risk-estimation-of-pulmonary-nodules-in-screening-cts-comparison-between-a-computer-model-and-human-observers
#19
Sarah J van Riel, Francesco Ciompi, Mathilde M Winkler Wille, Asger Dirksen, Stephen Lam, Ernst Th Scholten, Santiago E Rossi, Nicola Sverzellati, Matiullah Naqibullah, Rianne Wittenberg, Marieke C Hovinga-de Boer, Miranda Snoeren, Liesbeth Peters-Bax, Onno Mets, Monique Brink, Mathias Prokop, Cornelia Schaefer-Prokop, Bram van Ginneken
PURPOSE: To compare human observers to a mathematically derived computer model for differentiation between malignant and benign pulmonary nodules detected on baseline screening computed tomography (CT) scans. METHODS: A case-cohort study design was chosen. The study group consisted of 300 chest CT scans from the Danish Lung Cancer Screening Trial (DLCST). It included all scans with proven malignancies (n = 62) and two subsets of randomly selected baseline scans with benign nodules of all sizes (n = 120) and matched in size to the cancers, respectively (n = 118)...
2017: PloS One
https://www.readbyqxmd.com/read/29120665/screening-for-lung-cancer-using-sub-millisievert-chest-ct-with-iterative-reconstruction-algorithm-image-quality-and-nodule-detectability
#20
Zhang Miao, Qi Weiwei, Sun Ye, Jiang Yan, Liu Xiaoyi, Nan Hong
OBJECTIVE: To investigate the image quality and nodules detectability using ultra-low dose (ULD) protocol with iterative model reconstruction (IMR) algorithm when compared to routine low dose (LD) chest CT in lung cancer screening. METHODS: Chest CT scans were acquired using a 256-slice scanner for 300 subjects. The scan protocol for ULD group was 120kVp/17mAs while the LD group was 120kVp/30mAs. All images were reconstructed with filtered back projection (FBP), hybrid iterative reconstruction (HIR) and IMR algorithms...
November 9, 2017: British Journal of Radiology
keyword
keyword
107435
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"