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Joana P A Ferreira, Isabel Miranda, Vicelina B Sousa, Helena Pereira
The bark from Quercus faginea mature trees from two sites was chemically characterized for the first time. The barks showed the following composition: ash 14.6%, total extractives 13.2%, suberin 2.9% and lignin 28.2%. The polysaccharides were composed mainly of glucose and xylose (50.3% and 35.1% of all monosaccharides respectively) with 4.8% of uronic acids. The suberin composition was: ω-hydroxyacids 46.3% of total compounds, ɑ,ω-alkanoic diacids 22.3%, alkanoic acids 5.9%, alkanols 6.7% and aromatics 6...
2018: PloS One
Patricia Reboredo-Rodríguez, Carmen González-Barreiro, Beatriz Cancho-Grande, Tamara Y Forbes-Hernández, Massimiliano Gasparrini, Sadia Afrin, Danila Cianciosi, Alegría Carrasco-Pancorbo, Jesús Simal-Gándara, Francesca Giampieri, Maurizio Battino
The aim of the present work was to evaluate the phenolic profile of the 'Brava' extra virgin olive oil and assess its potential as a "natural adjuvant" in combination with chemotherapy treatment. The total phenol content of the phenolic extracts was 764 mg gallic acid equivalents/kg and the total antioxidant capacity was 2309, 1881 and 2088 μM trolox equivalents/kg determined by Diphenyl-1-picrylhydrazyl free radical method, Ferric Reducing Antioxidant Power and Trolox Equivalent Antioxidant Capacity assay, respectively...
May 10, 2018: Food and Chemical Toxicology
Liliana Mihalcea, Mihaela Turturică, Vasilica Barbu, Elena Ioniţă, Livia Pătraşcu, Mihaela Cotârleţ, Loredana Dumitraşcu, Iuliana Aprodu, Gabriela Râpeanu, Nicoleta Stănciuc
Sea buckthorn carotenoids extracted using CO2 supercritical fluids method were encapsulated within whey proteins isolate by transglutaminase (TG) mediated crosslinking reaction, coacervation and freeze drying. The encapsulation efficiency was 36.23 ± 1.58%, with β-carotene the major carotenoid present in the powder. The confocal analysis revealed that TG-ase mediated cross-linking reaction enhanced the complexes stability to such a manner that a double microencapsulation was performed. The powder showed an antioxidant activity of 2...
October 1, 2018: Food Chemistry
Zhifeng Li, Hui Wen Lee, Xu Liang, Dong Liang, Qi Wang, Dejian Huang, Choon Nam Ong
The phenolic profiles of 12 cruciferous vegetables (pakchoi, choysum, Chinese cabbage, kailan, Brussels sprout, cabbage, cauliflower, broccoli, rocket salad, red cherry radish, daikon radish, and watercress) were studied with UHPLC-MS/MS. Antioxidant activity and total phenolic content (TPC) were also evaluated. A total of 74 phenolic compounds were identified, including 16 hydroxycinnamic acids and derivatives, and 58 flavonoids and derivatives. The main flavonoids identified were glycosylated quercetin, kaempferol and isorhamnetin, and the main hydroxycinnamic acids were ferulic, sinapic, caffeic and p -coumaric acids...
May 10, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Adriano Mollica, Gokhan Zengin, Marcello Locatelli, Carene Marie Nancy Picot-Allain, Mohamad Fawzi Mahomoodally
Allium species have been widely used for culinary and medicinal purposes. This study attempts for the first time to investigate into the enzyme inhibitory potential of different plant parts of Allium scorodoprasum L. subsp. rotundum (L.) Stearn, also known as wild garlic or leek in Turkey. The antioxidant and enzyme inhibitory potential of the flower, stem, and bulb extracts of A. scorodoprasum were assessed using in vitro bio-assays. The phenolic composition of the different plant parts was also established...
June 2018: Food Research International
Saravanan Shanmugam, Isla Alcântara Gomes, Marina Denadai, Bruno Dos Santos Lima, Adriano Antunes de Souza Araújo, Narendra Narain, Maria Terezinha Santos Leite Neta, Mairim Russo Serafini, Lucindo José Quintans-Júnior, Parimelazhagan Thangaraj
The diabetic key enzymes inhibition, nutritional, antioxidant activity and bioactive compounds identification of Passiflora subpeltata fruit pulp were investigated. Fifteen polyphenolic compounds including protocatechuic acid, ferulic acid, vanillic acid, epicatechin, p-coumaric acid, cinnamic acid, eriodictyol and quercetin-3-glucoside were identified in the pulp of this species by using UHPLC-QqQ-MS/MS analysis. The total carbohydrates and crude protein contents in fruit pulp were 2.62 mg glucose equivalent/g sample fruit pulp and 8...
June 2018: Food Research International
Selina A Fyfe, Gabriele Netzel, Michael E Netzel, Yasmina Sultanbawa
The green plum is the fruit of Buchanania obovata Engl. and is an Australian Indigenous bush food. Very little study has been done on the green plum, so this is an initial screening study of the functional properties and phytochemical profile found in the flesh and seed. The flesh was shown to have antimicrobial properties effective against gram negative ( Escherichia coli 9001—NCTC) and gram positive ( Staphylococcus aureus 6571—NCTC) bacteria. Scanning electron microscopy analysis shows that the antimicrobial activity causes cell wall disintegration and cytoplasmic leakage in both bacteria...
May 4, 2018: Foods (Basel, Switzerland)
Xuelian Yang, Pei Cai, Qiaohong Liu, Jiajia Wu, Yong Yin, Xiaobing Wang, Lingyi Kong
A series of multitargeted 8-hydroxyquinoline derivatives were designed and synthesized for the treatment of Alzheimer's disease (AD). In vitro studies indicated that most of the prepared compounds exhibited significant inhibitory effects against self-induced Aβ1-42 aggregation and potential antioxidant properties especially compound 5b (IC50  = 5.64 μM for self-induced Aβ aggregation; the oxygen radical absorbance capacity using fluorescein (ORAC-FL) value is 2.63 Trolox equivalents). Notably, 5b can chelate biometals and inhibit Cu2+ /Zn2+ -induced Aβ1-42 aggregation...
April 22, 2018: Bioorganic & Medicinal Chemistry
Jiao-Jiao Zhang, Ya Li, Sheng-Jun Lin, Hua-Bin Li
The waste of Sterculia nobilis fruit was massively produced during food processing, which contains lots of natural antioxidants. In this study, antioxidants in the Sterculia nobilis fruit waste were extracted using the green microwave-assisted extraction (MAE) technique. The effects of five independent variables (ethanol concentration, solvent/material ratio, extraction time, temperature, and microwave power) on extraction efficiency were explored, and three major factors (ethanol concentration, extraction time, and temperature) showing great influences were chosen to study their interactions by response surface methodology...
May 2, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Ismail Abiola Adebayo, Hasni Arsad, Mohd Razip Samian
Background: Academic reports have confirmed Moringa oleifera leaves to possess significant antioxidant capacities; however, such studies are unavailable for its ripe seeds even though they are more desirous for consumption due to their sweet taste. Objective: In this study, we investigated antioxidant capacities of four polar extracts (crude water, ethanol, butanol, and aqueous residue) from the plant's ripe seeds. Materials and Methods: Phytochemicals were extracted from the ripe seeds of M...
April 2018: Pharmacognosy Magazine
Hassan Abu-Qaoud, Nuha Shawarb, Fatima Hussen, Nidal Jaradat, Munqez Shtaya
Borago officinalis plant is an important plant of high medicinal and nutritional values. This study designed to evaluate antioxidant activity, screen the existence of phytogenic chemical compounds and to determine the total flavonoid and phenol contents of wild and cultivated Borago officinalis. Total flavonoid contents of the wild and cultivated Borago officinalis were determined by using rutin reference standard method and total phenols determined by using Folin Ciocalteu's method while antioxidant activity evaluated by using 2, 2-diphenyl-1-picryl-hydrazyl-hydrate assay...
May 2018: Pakistan Journal of Pharmaceutical Sciences
Hadis Mozaffari, Elnaz Daneshzad, Pamela J Surkan, Leila Azadbakht
OBJECTIVE: Measurement of dietary total antioxidant capacity (DTAC) is considered a new holistic dietary approach and assesses total antioxidants present in the overall diet. Our aim was to perform a comprehensive review of the literature on the association between DTAC and cardiovascular disease (CVD) risk factors. METHODS: PubMed, Web of Science, and Scopus were used to conduct a comprehensive search for articles published on this topic through September 2017...
May 1, 2018: Journal of the American College of Nutrition
Satish Kanhar, Atish Kumar Sahoo, Ajay Kumar Mahapatra
The purpose of this study was to evaluate ameliorative effects of Homalium nepalense Benth. (Flacourtiaceae) on CCl4 -induced hepatocellular injury in rats. Oxygen-radical absorbance-capacity (ORAC) and cell-based-antioxidant-protection-in-erythrocytes (CAP-e) were performed and found that the ethyl acetate fractions of bark (HNEB) and leaf (HNEL) showed a remarkable degree of antioxidant activities in a dose dependent manner. Antioxidant potential HNEB was higher than HNEL and was comparable with trolox. HNEB and HNEL at 300 and 400 mg/kg showed significant hepatoprotective activities against CCl4 -induced hepatotoxicity as evidenced by restoration of SGOT, SGPT, ALP, TB and TP level...
April 23, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Hugo Vilhena, Marta Figueiredo, José Cerón, Josep Pastor, Sónia Miranda, Hélder Craveiro, Maria A Pires, Fernando Tecles, Camila P Rubio, Roman Dabrowski, Sofia Duarte, Ana C Silvestre-Ferreira, Asta Tvarijonaviciute
Acute phase proteins (APP) and biomarkers of oxidative status have proved to be clinically useful biomarkers of pyometra in different species. Despite pyometra is considered one of the most important feline reproductive diseases, information about the APP response and the oxidative status in queens with pyometra is lacking. This study aimed to evaluate the APP and the antioxidant responses at diagnosis and in the post-operative period in feline pyometra. Serum concentrations of serum amyloid A (SAA), haptoglobin (Hp), albumin, total serum thiols (Thiol) and total antioxidant capacity determined by different assays, including trolox equivalent antioxidant capacity (TEAC) assessed by two different methodologies (TEAC1 and TEAC2), ferric reducing ability of plasma (FRAP), and cupric reducing antioxidant capacity (CUPRAC), were determined in 23 queens with pyometra at diagnosis and in 13 healthy control queens submitted to elective ovariohysterectomy...
April 22, 2018: Theriogenology
Seon Min Woo, Seung Un Seo, Kyoung-Jin Min, Seung-Soon Im, Ju-Ock Nam, Jong-Soo Chang, Shin Kim, Jong-Wook Park, Taeg Kyu Kwon
Corosolic acid is one of the pentacyclic triterpenoids isolated from Lagerstroemia speciose and has been reported to exhibit anti-cancer and anti-proliferative activities in various cancer cells. In the present study, we investigated the molecular mechanisms of corosolic acid in cancer cell death. Corosolic acid induces a decrease of cell viability and an increase of cell cytotoxicity in human renal carcinoma Caki cells. Corosolic acid-induced cell death is not inhibited by apoptosis inhibitor (z-VAD-fmk, a pan-caspase inhibitor), necroptosis inhibitor (necrostatin-1), or ferroptosis inhibitors (ferrostatin-1 and deferoxamine (DFO))...
April 27, 2018: International Journal of Molecular Sciences
C E Lara-Hidalgo, L Dorantes-Álvarez, H Hernández-Sánchez, F Santoyo-Tepole, A Martínez-Torres, L Villa-Tanaca, C Hernández-Rodríguez
Three yeast strains were isolated from the spontaneous fermentation of guajillo pepper: Hanseniaspora opuntiae, Pichia kudriavzevii, and Wickerhamomyces anomalus, which were identified by amplification of the ITS/5.8S ribosomal DNA. Some probiotic characteristics of these strains were evaluated and compared with one commercial probiotic yeast (Saccharomyces boulardii). The survival percentage of all the yeasts was similar to that of the commercial product. They showed different hydrophobicity characteristics with hydrocarbons, autoaggregation > 90%, and characteristics of co-aggregation with pathogenic microorganisms...
April 25, 2018: Probiotics and Antimicrobial Proteins
Ignacio Migues, Nieves Baenas, Amadeo Gironés-Vilaplana, María Verónica Cesio, Horacio Heinzen, Diego A Moreno
The use of nutrient-rich foods to enhance the wellness, health and lifestyle habits of consumers is globally encouraged. Native fruits are of great interest as they are grown and consumed locally and take part of the ethnobotanic knowledge of the population. Pitanga is an example of a native fruit from Uruguay, consumed as a jelly or an alcoholic beverage. Pitanga has a red-violet pigmentation, which is a common trait for foods that are a good source of antioxidants. Hence, fruits from different Uruguayan regions were analyzed via miniaturized sample preparation method, HPLC-DAD-ESI/MSn and RP-HPLC-DAD techniques to identify and quantify phenolic compounds, respectively...
April 24, 2018: Foods (Basel, Switzerland)
Lorena Franco-Martínez, Diego Romero, Camila Peres Rubio, Fernando Tecles, Silvia Martínez-Subiela, Mariana Teles, Asta Tvarijonaviciute
The aim of the present report was to develop and validate new automated spectrophotometric assays for measurement of total antioxidant capacity (TAC), thiols, and advanced oxidation protein products (AOPP) in mussel gills, digestive gland and hemolymph samples, and to evaluate their possible utility in biomonitoring programs. Total antioxidant capacity (TAC) was measured by different methods: trolox equivalent antioxidant capacity (TEAC1 and TEAC2), cupric reducing antioxidant capacity (CUPRAC), and ferric reducing ability of plasma (FRAP)...
April 22, 2018: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
Andrea Del Pilar Sánchez-Camargo, Natalia Pleite, José Antonio Mendiola, Alejandro Cifuentes, Miguel Herrero, Bienvenida Gilbert-López, Elena Ibáñez
In the present work, the valorization of Nannochloropsis gaditana biomass is proposed within the concept of biorefinery. To this aim, high-pressure homogenization (HPH) was used to break down the strong cell wall and supercritical fluid extraction (SFE) with pure CO2 was applied as a first step to extract valuable compounds (such as non-polar lipids and pigments). Extraction of the remaining residue for the recovery of bioactive compounds was studied by means of an experimental design based on response surface methodology (RSM) employing pressurized liquid extraction (PLE) with green solvents such as water and ethanol...
April 23, 2018: Electrophoresis
Jia Jiang, Shuang Zang, Dan Li, Kun Wang, Sizhu Tian, Aimin Yu, Ziwei Zhang
Electron spin resonance spectroscopy was applied to determining the antioxidant capacity of eight thiol-containing compounds, including reduced glutathione, N-acetyl-L-cycsteine, methimazole, captopril, and tiopronin with one thiol group, 1,4-dithioerythritol and 2,3-dimercapto-1-propanol with two thiol groups, as well as L-cystine with no free thiol group. Cu2+ ion gives an electron spin resonance signal and is reduced to Cu+ ion with no electron spin resonance signal by the free thiol group in the compounds...
July 1, 2018: Talanta
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