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Venous disorders

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https://www.readbyqxmd.com/read/29455215/stroke-and-seizure-continue-to-be-the-major-brunt-of-in-patient-neurology-care-an-observation-from-teaching-hospital
#1
Azra Zafar, Majed Alabdali, Rizwana Shahid, Danah Aljaafari, Fahd A Al-Khamis, Aishah I Albakr, Saima Nazish, Abdulla A Al-Sulaiman, Alon Abraham
OBJECTIVE: To assess the burden and describe the pattern of neurological disorders requiring admissions in a teaching hospital of Al Khobar. METHODS: This is a retrospective, cross sectional study, carried out in the Neurology Department of King Fahd Hospital of the University from January 2009 to December 2016. Neurological disorders were grouped as ischemic stroke, intracerebral hemorrhage, transient ischemic attack, cerebral venous sinus thrombosis, seizure disorders, central nervous system infection, multiple sclerosis, neuropathies, myopathies, headache, dementia and miscellaneous group...
January 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29452906/extracranial-arterial-wall-volume-is-increased-and-shows-relationships-with-vascular-mri-measures-in-idiopathic-parkinson-s-disease
#2
Stephen Ball, Sarah Al-Bachari, Laura M Parkes, Hedley C A Emsley, Charles N McCollum
OBJECTIVE: Idiopathic Parkinson's disease (IPD) is the second most common neurodegenerative disorder, often complicated by dementia. Cardiovascular risk factors and spontaneous cerebral emboli (SCE) are strongly associated with Alzheimer's (AD) and vascular dementia (VaD). We measured SCE in the middle cerebral artery and arterial wall volume in the extracranial arteries in patients with IPD and controls, and explored the relationships with structural and physiological MRI brain neurovascular measures...
February 10, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29452321/hypoplastic-straight-sinus-with-persistent-falcine-sinus-in-an-adult-with-sinus-pericranii
#3
Lukas Andereggen, Rajeev K Verma
Open MRI of a 45-year-old man with panic disorder showed a sinus pericranii (SP). Examination of the scalp revealed a discolored scalp mass and MR venography displayed a hypoplastic straight sinus with persistent falcine sinus. SP is a venous anomaly consisting of a transosseous vascular channel connecting an intracranial sinus with subgaleal veins. High venous pressure in the late embryonic stage, as with a hypoplastic straight sinus, has been hypothesized to predispose affected individuals to develop other venous anomalies, i...
February 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29451331/sliding-free-transverse-rectus-abdominis-myocutaneous-flap-for-closure-of-a-massive-abdominal-wall-defect-a-case-report
#4
Annika Senghaas, Thomas Kremer, Volker J Schmidt, Leila Harhaus, Christoph Hirche, Ulrich Kneser, Amir K Bigdeli
Despite considerable advances in reconstructive surgery, massive abdominal wall defects continue to pose a significant surgical challenge. We report the case of a 72-year-old morbidly obese female patient with Clostridium septicum-related gas gangrene of the abdominal wall. After multidisciplinary treatment and multiple extensive debridements, a massive full-thickness defect (40 cm × 35 cm) of the right abdominal wall was present. The abdominal contents were covered with a resorbable mesh to prevent evisceration...
February 16, 2018: Microsurgery
https://www.readbyqxmd.com/read/29445932/fibrodysplasia-ossificans-progressiva-a-current-review-of-imaging-findings
#5
REVIEW
Adam H Bauer, Jeff Bonham, Luis Gutierrez, Edward C Hsiao, Daria Motamedi
OBJECTIVE: Fibrodysplasia ossificans progressiva is a rare genetic disorder characterized by congenital skeletal deformities and soft tissue masses that progress to heterotopic ossification. Deformities of the great toes are distinctive, and heterotopic ossification in the soft tissues follows an expected anatomic and temporal pattern. In addition to heterotopic ossification, osteochondromata, middle ear ossification, demyelination, lymphedema, and venous thrombosis are characteristic...
February 14, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29443727/acute-bilateral-retina-hemorrhages-beneath-internal-limiting-membrane-an-unusual-ophthalmological-case-report-of-acute-leukemia-during-complete-clinical-remission
#6
Shuyuan Lyu, Ming Zhang, Yunxia Gao
RATIONALE: Leukemia is a common hematologic disease that causes various systemic complications, such as ophthalmological disorders. The venous congestion is considered to be the main clinical sign that occurs during the initial stage of the disease, whereas white-centered hemorrhages are the most typical manifestations in leukemic retinopathy. These complications usually manifest when the disease presents with clinical and hematological symptoms. In the present study, we report a patient who was diagnosed with leukemic retinopathy...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29441984/direct-oral-anticoagulants-in-real-clinical-practice-analysis-of-patient-characteristics-and-prescribing-patterns-in-a-large-teaching-hospital
#7
B Kováčová, J Červeňová
Direct oral anticoagulants (DOACs) became rapidly accepted as an alternative to warfarin in the prevention of stroke in atrial fibrillation and prophylaxis of thromboembolic events. Their safety and efficacy have been well documented in several studies, however, as with any new drug, use in real-world population often reveals risk factors that may affect treatment outcomes. The aim of the study was to determine the prescribing patterns and analyse patient characteristics to identify incidence of selected factors (age, weight, comorbidities and interacting medication) that may affect DOAC safety and efficacy...
September 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29434493/comparative-study-of-complications-in-cv-catheter-insertion-for-pediatric-patients-real-time-ultrasound-guided-versus-venography-guided-approach
#8
Shuichi Takano, Norio Shimizu, Naruo Tokuyasu, Teruhisa Sakamoto, Soichiro Honjo, Keigo Ashida, Hiroaki Saito, Yoshiyuki Fujiwara
Background: Tunneled central venous catheters (CVC), called Broviac/Hickman catheter, are widely used in the long-term treatment of pediatric patients. Recently, the percutaneous approach for CVC insertion has become dominant as a less invasive intervention. In this study, we reviewed the mechanical and delayed complications according to different procedures of CVC insertion and assessed the risk factors for complications in CVC insertions for pediatric patients. Methods: A total of 159 pediatric patients (85 males and 74 females) were included in this study...
December 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/29431912/polymorphism-in-dural-arteriovenous-fistula-matrix-metalloproteinase-2-1306-c-t-as-a-potential-risk-factor-for-sinus-thrombosis
#9
Yuang-Seng Tsuei, Ying-Erh Chou, Wen-Hsien Chen, Chao-Bao Luo, Shun-Fa Yang
BACKGROUND: Dural arteriovenous fistula (DAVF) is a rare but important cerebrovascular disorder in adults. Little is known about the molecular genetic pathogenesis underlying the development of DAVF. OBJECTIVES: The present study was conducted to investigate the associations of gene polymorphisms and DAVF. MATERIALS AND METHODS: Using real-time polymerase chain reaction (PCR) genotyping, 7 single-nucleotide polymorphisms (SNPs) of angiogenesis-related genes were analyzed in 72 DAVF patients...
February 12, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29431904/atrial-fibrillation-and-venous-thromboembolism-evidence-of-bidirectionality-in-the-atherosclerosis-risk-in-communities-study
#10
P L Lutsey, F L Norby, A Alonso, M Cushman, L Y Chen, E D Michos, A R Folsom
BACKGROUND: Atrial fibrillation (AF) and venous thromboembolism (VTE) frequently co-occur. These conditions have shared risk factors and are accompanied by coagulation abnormalities. Furthermore, mechanistic pathways may directly link the disorders. OBJECTIVES: To test the hypothesis that individuals with incident AF are at greater risk of developing VTE, and those with VTE are at elevated risk of AF. We also tested whether associations were stronger in the first 6 months after the initial diagnosis, and explored race differences...
February 12, 2018: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29430432/hughes-stovin-syndrome-as-an-outcome-of-beh%C3%A3-et-disease-or-as-a-different-entity
#11
Serkan Demirkan, Yıldırım Gültekin
Hughes-Stovin syndrome is a rare disorder of unknown etiology. Although the association between multiple pulmonary artery aneurysms and venous thrombosis of the lower limbs was reported by Beattie and Hall in 1911, it was not until 1962 that the eponym "Hughes-Stovin syndrome" was formally introduced in the medical literature. We describe 2 patients with Hughes-Stovin syndrome who presented with pulmonary artery aneurysm, thrombophlebitis, hemoptysis, and oral ulcers, review the manifestations of the disease, and compare its similarities with and differences from Behçet disease...
February 2018: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29423659/venous-thromboembolism-during-treatment-with-antipsychotics-a-review-of-current-evidence
#12
REVIEW
Anna K Jönsson, Johan Schill, Hans Olsson, Olav Spigset, Staffan Hägg
This article summarises the current evidence on the risk of venous thromboembolism (VTE) with the use of antipsychotics. An increasing number of observational studies indicate an elevated risk of VTE in antipsychotic drug users. Although the use of certain antipsychotics has been associated with VTE, current data can neither conclusively verify differences in occurrence rates of VTE between first- and second-generation antipsychotics or between individual compounds, nor identify which antipsychotic drugs have the lowest risk of VTE...
February 8, 2018: CNS Drugs
https://www.readbyqxmd.com/read/29419563/a-nonsurgical-approach-to-mesenteric-vascular-disease
#13
Hossein Tabriziani, Armaghan Ahmad, Roberto Bergamaschi, William H Frishman
Mesenteric ischemia is a rare disorder, with considerably high morbidity and mortality rates. It can manifest in several ways, including acute mesenteric ischemia, chronic mesenteric ischemia, nonocclusive mesenteric ischemia, mesenteric venous thrombosis, and colonic ischemia. Of these, acute mesenteric ischemia is the most severe form of intestinal ischemia, with a high mortality rate. The mainstay of therapy for mesenteric ischemia is surgical exploration and resection of infarcted bowel; however, medical therapy can play an important adjunctive role...
March 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29398225/papillophlebitis-in-a-young-male-patient-with-buerger-s-disease
#14
J A Reche-Sainz, O Gutiérrez-Montero
CLINICAL CASE: A 27-year-old male with sudden visual loss of OD. He had a past history of heavy smoking, as well as a chronic ischaemia of his left lower limb of one-year onset. This led to a diagnosis of Buerger's disease, which is an inflammatory thrombotic disorder that affects small and medium vessels. The visual acuity (VA) of OD was 0.9, and in the funduscopy a very congestive papilla was observed, along with venous tortuosity, scattered retinal haemorrhages, but without macular oedema...
February 1, 2018: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/29396996/intranasal-ketamine-and-its-potential-role-in-cancer-related-pain
#15
Vinita Singh, Theresa W Gillespie, R Donald Harvey
Cancer-related pain continues to be a significant therapeutic challenge, made more difficult by contemporary opioid use and diversion concerns. Conventional treatment utilizing a tiered approach of non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and adjuvant agents is limited; and alternatives are needed for patients with rapidly progressing pain and those who develop hyperalgesia and tolerance to opioids. Ketamine, an N-methyl-D-aspartate (NMDA) selective antagonist, has historically been used for anesthesia in adult and pediatric populations, but has also been investigated for depression, bipolar disorder, and general and post-operative pain management...
February 3, 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29391714/comparative-analysis-of-the-oxidative-stress-and-antioxidant-status-in-type-ii-diabetics-and-nondiabetics-a-biochemical-study
#16
Archana Nair, Bindu J Nair
Background: Diabetes mellitus is a metabolic disorder characterized by hyperglycemia along with biochemical alterations of glucose and lipid peroxidation. It produces free radicals that induce lipid peroxidation which acts as an indicator for oxidative stress in the body. The widely used assay for lipid peroxidation involves measurement of malondialdehyde (MDA). Defensive system in the body consists of antioxidant enzymes which help in scavenging free radicals. Two such antioxidant enzymes are reduced glutathione (GSH) and superoxide dismutase (SOD)...
September 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29391677/endocrine-abnormalities-in-adolescents-with-menstrual-disorders
#17
Siddhesh R Rajiwade, Haritha Sagili, R Soundravally, L Subitha
Purpose: To look for endocrine abnormalities like thyroid disorders, hyperprolactinemia, hyperandrogenism and PCOS among adolescents with menstrual disorders and to compare the above endocrine status with those without menstrual disorders. Methods: This was a case-control study carried out in adolescent girls aged 10-19 years in gynecology outpatient department of a tertiary care hospital. Sample of venous blood (5 ml) was taken for hormonal studies as clinically indicated-thyroid function test, serum prolactin, total testosterone, which were analyzed by chemiluminescence system...
February 2018: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/29389674/inherited-factor-ii-deficiency-with-paradoxical-hypercoagulability-a-case-report
#18
Harold Watson, Ariel Perez, Kwabena Ayesu, Faisal Musa, Jose Sarriera, Mario Madruga, Steve J Carlan
: Congenital deficiency of factor II is a very rare autosomal recessive disorder that can result in a bleeding diathesis. Genotypically, individuals are either homozygous for a defective prothrombin gene or a compound heterozygote with different mutated prothrombin genes inherited from each parent. Phenotypically, it is characterized by either a low production of normal prothrombin or a near-normal production of dysfunctional prothrombin. Treatment is aimed at restoring normally functioning factor II circulating levels to sufficient concentration for hemostasis...
January 31, 2018: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/29388188/the-paracelsus-score-a-novel-diagnostic-tool-for-pyoderma-gangrenosum
#19
F Jockenhöfer, U Wollina, K A Salva, S Benson, J Dissemond
BACKGROUND: The lack of objective diagnostic criteria renders pyoderma gangrenosum (PG) a diagnosis of exclusion. The diagnostic approaches proposed to date have not been systematically evaluated. Thus, PG remains a challenging and frequently misdiagnosed disorder. OBJECTIVES: To develop and assess a comprehensive yet clinically practicable as well as sensitive diagnostic scoring system for PG. METHODS: Clinical history and images of a total of 60 subjects with previously confirmed PG located on the lower extremity as well as a control cohort of 50 patients with venous leg ulcers were retrospectively evaluated by expert teams at two tertiary dermatological centres specializing in wound care using a newly developed diagnostic scoring system composed of ten criteria...
February 1, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29387895/-the-conspicuous-leg
#20
REVIEW
S M Schellong
Symptoms of the leg or of both legs, may indicate a need for evaluation and/or treatment, which must be clarified urgently or even as an emergency situation. Among the diseases which must be considered from a vascular viewpoint are critical limb ischemia, suspicion of deep leg vein thrombosis and special forms of venous insufficiency. With respect to infections erysipelas and the syndrome of infected diabetic foot must be considered as well as peripheral and central leg paresis as orthopedic and neurological disorders, respectively...
January 31, 2018: Der Internist
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