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https://www.readbyqxmd.com/read/29452377/discordance-in-the-dependence-on-kisspeptin-signaling-in-mini-puberty-vs-adolescent-puberty-human-genetic-evidence
#1
Muhammad Shahab, Margaret Lippincott, Yee-Ming Chan, Addie Davies, Paulina M Merino, Lacey Plummer, Veronica Mericq, Stephanie Seminara
Context: Hypothalamic kisspeptin signaling plays a critical role in the initiation and maintenance of reproductive function. Biallelic mutations in the coding sequence of KISS1R (GPR54) have been identified in patients with idiopathic hypogonadotropic hypogonadism (IHH), but it is unknown whether biallelic variants can also be associated with related reproductive disorders. Case description: A missense homozygous variant (c.890G>T p.R297L) in KISS1R was identified in a child who presented with microphallus and bilateral cryptorchidism...
February 14, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29447448/gendered-racism-and-the-sexual-and-reproductive-health-of-black-and-latina-women
#2
Lisa Rosenthal, Marci Lobel
OBJECTIVE: To understand health disparities, it is important to use an intersectional framework that examines unique experiences of oppression faced by particular groups due to their intersecting identities and social positions linked to societal structures. We focus on Black and Latina women and their experiences with 'gendered racism' - unique forms of oppression due to the intersection of race/ethnicity and gender - to foster understanding of disparities between Black and Latina versus White women in sexual and reproductive health outcomes in the U...
February 15, 2018: Ethnicity & Health
https://www.readbyqxmd.com/read/29447271/parents-knowledge-beliefs-and-acceptance-of-the-hpv-vaccination-in-relation-to-their-socio-demographics-and-religious-beliefs-a-cross-sectional-study-in-thailand
#3
Maria Grandahl, Seung Chun Paek, Siriwan Grisurapong, Penchan Sherer, Tanja Tydén, Pranee Lundberg
Thailand has one of the world's highest prevalence of cervical cancer, mainly caused by the human papillomavirus (HPV). HPV infections can successfully be prevented by vaccination, which is available at a cost but not yet implemented in the national vaccination program. Parents play a critical role in deciding whether to vaccinate their child against HPV. Thus, the aim was to examine the association between parents' knowledge, beliefs, and acceptance of the HPV vaccination for their daughters, considering their socio-demographics and religious beliefs...
2018: PloS One
https://www.readbyqxmd.com/read/29445980/challenges-and-facilitators-to-promoting-a-healthy-food-environment-and-communicating-effectively-with-parents-to-improve-food-behaviors-of-school-children
#4
Hiershenee B Luesse, Rachel Paul, Heewon L Gray, Pamela Koch, Isobel Contento, Victoria Marsick
Background Childhood obesity is a major public health concern and families play an important role. Improving strategies to reach parents and directing tailored nutrition education to them is needed. Purpose To investigate the challenges and facilitators to promoting a healthy environment at home and to identify communication preferences to inform intervention strategies for effectively reaching low-income urban minority families. Procedure Semi-structured focus group interviews were conducted with four groups involving 16 low-income urban parents (94% female; 88% Hispanic/Latino, 12% African American) of elementary school children...
February 14, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29444654/the-comparison-of-perceived-health-related-quality-of-life-between-australian-children-with-severe-specific-language-impairment-to-age-and-gender-matched-peers
#5
Kristy Nicola, Pauline Watter
BACKGROUND: Children with specific language impairment often present with multiple comorbidities, which may adversely affect both participation in play and academic performance, potentially impacting a child's health-related quality of life. This study 1) explored the suitability of the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales (PedsQL™) for use with a typically developing Australian control group, and 2) compared the health-related quality of life between a control group and Australian children with severe specific language impairment...
February 14, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29439695/male-partner-involvement-in-increasing-the-uptake-of-infant-antiretroviral-prophylaxis-treatment-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#6
Noah F Takah, Jeannine A Atem, Leopold N Aminde, Moffat Malisheni, Grant Murewenhema
BACKGROUND: Infant antiretroviral prophylaxis plays an important role towards ensuring the reduction of HIV transmission from mother to child in the postpartum period. However in sub Saharan Africa (SSA), the low level of involvement of male partners may hinder the uptake of such services by HIV positive mothers. We conducted a systematic review and meta-analysis to determine the impact of male partner involvement approaches on the uptake of infant antiretroviral prophylaxis in SSA. METHODS: In this systematic review and meta-analysis, Ovid Medline, Embase, PsycINFO, Cochrane library, ClinicalTrials...
February 13, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29433666/similarities-and-differences-in-child-development-from-birth-to-age-3-years-by-sex-and-across-four-countries-a-cross-sectional-observational-study
#7
Ilgi Ozturk Ertem, Vibha Krishnamurthy, Mphelekedzeni C Mulaudzi, Yanina Sguassero, Hakan Balta, Ozlem Gulumser, Burcu Bilik, Roopa Srinivasan, Benjamin Johnson, Geliang Gan, Lisa Calvocoressi, Veronika Shabanova, Brian W C Forsyth
BACKGROUND: Knowledge about typical development is of fundamental importance for understanding and promoting child health and development. We aimed to ascertain when healthy children in four culturally and linguistically different countries attain developmental milestones and to identify similarities and differences across sexes and countries. METHODS: In this cross-sectional, observational study, we recruited children aged 0-42 months and their caregivers between March 3, 2011, and May 18, 2015, at 22 health clinics in Argentina, India, South Africa, and Turkey...
March 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29432600/early-life-parent-child-relationships-and-adult-children-s-support-of-unpartnered-parents-in-later-life
#8
I-Fen Lin, Hsueh-Sheng Wu
Objectives: The proportion of older adults who are unpartnered has increased significantly over the past 25 years. Unpartnered older adults often rely on their adult children for support. Most previous studies have focused on proximal factors associated with adult children's support of their parents, while few have examined distal factors, such as parent-child relationships formed during childhood. This study fills the gap by investigating the direct and indirect associations between early-life parent-child relationships and adult children's upward transfers to unpartnered parents...
February 8, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29432550/strategies-for-prediction-and-mitigation-of-radiation-induced-liver-toxicity
#9
Diego A S Toesca, Bulat Ibragimov, Amanda J Koong, Lei Xing, Albert C Koong, Daniel T Chang
Although well described in the 1960s, liver toxicity secondary to radiation therapy, commonly known as radiation-induced liver disease (RILD), remains a major challenge. RILD encompasses two distinct clinical entities, a 'classic' form, composed of anicteric hepatomegaly, ascites and elevated alkaline phosphatase; and a 'non-classic' form, with liver transaminases elevated to more than five times the reference value, or worsening of liver metabolic function represented as an increase of 2 or more points in the Child-Pugh score classification...
February 8, 2018: Journal of Radiation Research
https://www.readbyqxmd.com/read/29432474/community-knowledge-perceptions-and-attitudes-regarding-leprosy-in-rural-cameroon-the-case-of-ekondotiti-and-mbonge-health-districts-in-the-south-west-region
#10
Earnest Njih Tabah, Dickson Shey Nsagha, Anne-Cecile Zoung-Kanyi Bissek, Theophilus Ngeh Njamnshi, Irine Ngani-Nformi Njih, Gerd Pluschke, Alfred Kongnyu Njamnshi
BACKGROUND: Although leprosy is one of the oldest diseases known to humanity, it remains largely misunderstood. Misconceptions about leprosy leads to stigma towards people with the disease. This study aimed at exploring the knowledge, perceptions and attitudes regarding leprosy in rural Cameroon. METHODS: We carried out a cross-sectional community survey of 233 respondents aged 15-75 years, free from leprosy, and living in two rural health districts of the South-west Region of Cameroon...
February 12, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29432246/evaluation-and-management-of-the-child-with-autism-spectrum-disorder
#11
Nicole Baumer, Sarah J Spence
PURPOSE OF REVIEW: Autism spectrum disorder is a neurodevelopmental disorder defined by deficits in social communication and the presence of restricted and repetitive behaviors and interests. This article provides the tools to diagnose and manage patients with autism spectrum disorder. RECENT FINDINGS: Autism spectrum disorder is a heterogeneous condition with varying presentations, multiple etiologies, and a number of comorbidities that impact the course and management of the disorder...
February 2018: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/29431293/il-17a-g197g-association-between-nox-and-gestational-age-in-a-south-african-birth-cohort
#12
P Nansook, R N Naidoo, S Muttoo, K Asharam, P Ramkaran, A Phulukdaree, A A Chuturgoon
Interleukin (IL-)17A, plays a role in pathogenic defence, but is implicated in chronic inflammatory diseases, and has recently been associated with variable pregnancy outcomes. We investigated the role of maternal IL-17-[G197A]-specific effects of third-trimester IL-17 mRNA expression, NOx exposure levels and other variables on gestational age, in the Mother and Child in the Environment (MACE) birth cohort in South Africa. A total of 327 participants were genotyped for IL-17-[G197A] by polymerase chain reaction restriction-fragment length polymorphism (PCR-RFLP)...
February 12, 2018: International Journal of Immunogenetics
https://www.readbyqxmd.com/read/29431128/correlates-of-intensity-specific-physical-activity-in-children-aged-9-11-years-a-multilevel-analysis-of-uk-data-from-the-international-study-of-childhood-obesity-lifestyle-and-the-environment
#13
Hannah J Wilkie, Martyn Standage, Fiona B Gillison, Sean P Cumming, Peter T Katzmarzyk
OBJECTIVES: Physical activity (PA) can provide numerous physical and psychological health gains, yet a low proportion of children in England are sufficiently active to accrue benefit. Analysing the correlates of PA from a socioecological perspective may help to identify factors that promote versus discourage PA. The purpose of the present study was to: (1) assess the relationships between a wide range of potential correlates and intensity-specific PA and (2) explore which correlates are associated with meeting government PA guidelines...
February 3, 2018: BMJ Open
https://www.readbyqxmd.com/read/29429569/function-of-child-anger-and-sadness-in-response-to-a-blocked-goal
#14
Lin Tan, Cynthia L Smith
Drawing from the functional theory of emotion, anger is proposed to serve adaptive functions such as motivating children to persist in overcoming difficulties to achieve their goals, whereas sadness helps children to shift attention away from goals that they determine cannot be attained. Despite the theorized importance of anger to persistence, it does not always relate to persistence in expected ways empirically; the role that sadness might play in how anger relates to persistence is often not considered even though children often experience both anger and sadness when goals are blocked...
February 8, 2018: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/29426324/role-of-parental-and-environmental-characteristics-in-toddlers-physical-activity-and-screen-time-bayesian-analysis-of-structural-equation-models
#15
Eun-Young Lee, Kylie D Hesketh, Ryan E Rhodes, Christina M Rinaldi, John C Spence, Valerie Carson
BACKGROUND: Guided by the Socialization Model of Child Behavior (SMCB), this cross-sectional study examined direct and indirect associations of parental cognitions and behavior, the home and neighborhood environment, and toddlers' personal attributes with toddlers' physical activity and screen time. METHODS: Participants included 193 toddlers (1.6 ± 0.2 years) from the Parents' Role in Establishing healthy Physical activity and Sedentary behavior habits (PREPS) project...
February 9, 2018: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29426302/the-relationship-of-undernutrition-psychosocial-factors-and-developmental-outcomes-of-children-in-extreme-poverty-in-ethiopia
#16
Berhanu Nigussie Worku, Teklu Gemechu Abessa, Mekitie Wondafrash, Marleen Vanvuchelen, Liesbeth Bruckers, Patrick Kolsteren, Marita Granitzer
BACKGROUND: Extreme poverty is severe deprivation of basic needs and services. Children living in extreme poverty may lack adequate parental care and face increased developmental and health risks. However, there is a paucity of literature on the combined influences of undernutrition and psychosocial factors (such as limited play materials, playground, playtime, interactions of children with their peers and mother-child interaction) on children's developmental outcomes. The main objective of this study was, therefore, to ascertain the association of developmental outcomes and psychosocial factors after controlling nutritional indices...
February 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29420100/innovative-clinical-training-site-for-psychiatric-mental-health-nurse-practitioner-students-elementary-school-based-group-therapy-manuscript-id-umhn-2017-0143
#17
Grace Hubbard, Cheryl L Woods-Giscombe, Ashley Hageman, Nyanyiwa Vimba
The aim of this clinical training site innovation is to develop accessible pediatric mental health clinical training sites for psychiatric mental health nurse practitioner (PMHNP) students. Mental health services in school settings provide treatment in the child's community and create opportunities for innovation and collaboration with teachers, school counselors, and school psychologists. School settings provide opportunities for early recognition of anxiety symptoms and accessible treatment that can help close the gap in clinical training sites for this population...
February 8, 2018: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/29417912/-friend-or-foe-in-the-pocket-the-role-of-the-individual-peergroup-and-parents-for-dys-functional-mobile-phone-use
#18
Karin Knop, Dorothée Hefner
Friend or Foe in the Pocket? - The Role of the Individual, Peergroup and Parents for (dys)functional Mobile Phone Use In order to provide consultative support to parents as well as to children and young people, background knowledge regarding the motives of mobile phone use, functions of usage, comprehension of the attraction of this all-round medium also as knowledge about potential hazards are essential. This study offers empirical results about potentials and risks. The peergroup plays an important role for riskful and problematic mobile phone involvement...
February 2018: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/29415681/prenatal-and-perinatal-risks-for-late-language-emergence-in-a-population-level-sample-of-twins-at-age-2
#19
Catherine L Taylor, Mabel L Rice, Daniel Christensen, Eve Blair, Stephen R Zubrick
BACKGROUND: Late Language Emergence (LLE) in the first two years of life is one of the most common parental concerns about child development and reasons for seeking advice from health professionals. LLE is much more prevalent in twins (38%) than singletons (20%). In studies of language development in twins without overt disability, adverse prenatal and perinatal environments have been reported to play a lesser role in the etiology of LLE than adverse postnatal environments. However, there is a lack of population-level evidence about prenatal and perinatal risk factors for LLE in twins...
February 7, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29414117/structural-differences-in-the-lower-extremities-in-children-aged-7-9-years-caused-by-playing-football-a-cross-sectional-study
#20
Salvador Diaz-Miguel, Eva Lopezosa-Reca, Salomon Benhamu-Benhamu, Ana Belen Ortega-Avila, Raquel García-De-La-Peña, Gabriel Gijon-Nogueron
BACKGROUND: Physical activity during childhood can be beneficial in the long term. However, this practice can influence the child's physiological development. The aim of this study was to determine whether the practice of soccer, in moderation, could be a risk factor for the inadequate development of the lower limb. METHODS: The study group was composed of 115 children, of whom 59 (mean age 8.03±0.89years) practised soccer 3 times a week and had a positive Physical Activity Questionnaire for Adolescents (PAQ-A) score, while a further 56 (mean age 7...
November 17, 2017: Foot
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