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An-Wei Chen, Shao-Hua Liu, Ying-Ying Huang, Tao Wang
BACKGROUND: Foam sclerotherapy is an effective treatment strategy for venous malformations (VMs). Stability is one of the characteristics of sclerosant foams that determine the sclerosing power. OBJECTIVE: To evaluate the clinical outcomes of sclerotherapy with prolonged half-life of hyaluronic acid (HA)-polidocanol (POL) foam for treating head and neck VMs. MATERIALS AND METHODS: Seventy patients with head and neck VMs were enrolled between October 2013 and January 2015 in Qilu Hospital Shandong University...
June 21, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
Darius K L Aw, Hao-Yun Yap, Luke H T Tay, Kiang-Hiong Tay, Tze-Tec Chong
Introduction: In general, arteriovenous malformations (AVMs) are extremely rare, with an incidence of only 1 in 100,000. They are rarer still in the hands and present variably with bleeding, heaviness, a pulsatile mass, pain, ulceration, or necrosis. Report: The case of a 25 year old man with a rapidly bleeding right thumb AVM is presented. Bleeding was torrential and life threatening within a matter of seconds. He had previously undergone surgical ligation and embolisation twice at another centre, without success...
2018: EJVES Short Reports
Ravul Jindal, D B Dekiwadia, Pinjala Rama Krishna, Ajay K Khanna, Malay D Patel, Shoaib Padaria, Roy Varghese
Venous ulcer is an extremely common aetiology of lower extremity ulceration, which affects approximately 1% population in most of the countries, and the incidence rate increases with age and female gender. Proper assessment and diagnosis of both the patient and ulcer are inevitable in order to differentiate venous ulcers from other lower extremity ulceration and to frame an adequate and individualised management plan. Venous ulcers generally persist for weeks to many years and are typically recurrent in nature...
April 2018: Indian Journal of Surgery
Alexander Gallagher
Interventional endoscopy and interventional radiology have led to the development of minimally invasive techniques for management of kidney and ureteral diseases in the dog and cat including idiopathic renal hematuria, ureteral obstruction, and ectopic ureters. Sclerotherapy is a renal-sparing chemical cauterization technique used in cases of idiopathic renal hematuria. Diagnosis of ureteral obstruction is challenging in some cases based on ultrasound alone and antegrade pyelography should be considered. Treatment options for obstructions include nephrostomy tubes, ureteral stents, and subcutaneous ureteral bypass devices...
June 14, 2018: Veterinary Clinics of North America. Small Animal Practice
Joseph Reis, Ahmad I Alomari, Cameron C Trenor, Denise M Adams, Steven J Fishman, Samantha A Spencer, Raja Shaikh, Anna P Lillis, Murali K Surnedi, Gulraiz Chaudry
OBJECTIVE: Patients with Klippel-Trénaunay syndrome (KTS) and congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal abnormalities (CLOVES) syndrome have central phlebectasia and enlarged persistent embryonic veins that are often incompetent and prone to thromboembolism. The purpose of the study was to determine the presence of phlebectasia and the incidence of symptomatic pulmonary embolism (PE). METHODS: A retrospective review was conducted of patients referred to the Vascular Anomalies Center at our institution during a 21-year period who were diagnosed with KTS and CLOVES syndrome...
July 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
Muhammad Harris Laghari, Michael F Byrne, Nazira Chatur, Alan Yau, Fergal Donnellan
No abstract text is available yet for this article.
January 2018: VideoGIE: an official video journal of the American Society for Gastrointestinal Endoscopy
So-Hyun Nam, Kyoung-Ah Kwon
BACKGROUND: Lymphatic malformations are histologically benign vascular structures that vary in anatomic lesion and size. Extensive head and neck lymphatic malformations may be life-threatening. In the present study, we described three difficult-to-treat infants with giant cervico-mediastinal lymphatic malformations accompanied by severe respiratory distress. CASE PRESENTATIONS: Case 1. A Korean girl born at a gestational age of 37 weeks and weighing 2920 g had a large cervical mass compressing the trachea...
June 15, 2018: Journal of Medical Case Reports
Adam M Hanif, Justin A Saunders, C Matthew Hawkins, Ted H Wojno, Hee Joon Kim
PURPOSE: Bleomycin sclerotherapy has been shown to be a viable treatment for lymphatic malformations. However, its use for these lesions confined to the orbit is becoming increasingly documented in the literature. In this study, we summarize the clinical manifestations and outcomes observed following percutaneous bleomycin sclerotherapy for orbital lymphatic malformation. METHODS: A 5-year retrospective chart review of patients with clinical, radiographic, and/or biopsy-confirmed diagnoses of orbital lymphatic malformation that received bleomycin sclerotherapy was conducted at the Emory Hospital and Clinics...
June 14, 2018: Orbit
Camille A Kezer, Neil Gupta
PURPOSE OF REVIEW: This article aims to review current therapeutic endoscopic treatments available for the management of gastrointestinal bleeding related to cirrhosis. RECENT FINDINGS: Endoscopic band ligation is an effective treatment for primary prophylaxis, acute bleeding, and secondary prophylaxis of esophageal varices as well as for acute bleeding and secondary prophylaxis of select gastric varices. Sclerotherapy is a treatment option for acute bleeding and secondary prophylaxis of esophageal varices when band ligation is technically difficult...
June 9, 2018: Current Gastroenterology Reports
Ayush Amin, Jonathan Tu, Jason T Salsamendi
The present report describes a case of cryotherapy ablation in a 35-year-old woman with a 1.5cm painful venous malformation in the right vastus lateralis muscle. After the patient had failed sclerotherapy, a single session of cryotherapy was performed that resulted in both technical and clinical success. At 8-month follow up there was no residual pain. The use of cryotherapy ablation for the treatment of an intramuscular venous malformation has only been previously described on one occasion. Based on our results, cryotherapy is a promising therapy for fast and safe treatment for patients with venous vascular malformations...
June 7, 2018: Annals of Vascular Surgery
Yuji Eso, Akihiro Furuta, Atsushi Takai, Ken Takahashi, Yoshihide Ueda, Hiroyuki Marusawa, Hiroshi Seno
AIM: In cases of symptomatic giant hepatic cysts, appropriate treatment is required to relieve symptoms. Ethanol, minocycline hydrochloride, and ethanolamine oleate have been conventionally used for ultrasound (US)-guided sclerotherapy. However, liquid sclerosing agents could mix with the residual fluid in the cyst and reduce their sclerotic effects. We performed US-guided microfoam sclerotherapy using polidocanol for three patients and evaluated its efficacy and safety. METHODS: Between May 2016 and March 2017, three female patients with symptomatic giant hepatic cysts were referred to our hospital...
June 7, 2018: Hepatology Research: the Official Journal of the Japan Society of Hepatology
Costantino Davide Critello, Antonino S Fiorillo, Maria Chiara Cristiano, Stefano de Franciscis, Raffaele Serra
Background and objectives Foam sclerotherapy is a clinical procedure for the treatment of unhealthy veins. The aim of this study was to investigate the effect of sulodexide (SUL) on stability of foams prepared using polidocanol (POL) and sodium tetradecyl sulfate (STS) detergents, more specifically with 0.25% aethoxysclerol and 0.2% Fibro-Vein sclerosing solutions. Methods Foams were produced by the Tessari method using three different weight ratios of POL-SUL and STS-SUL (1:0, 1:1, and 1:3). Results The half-life of STS foams resulted as follows: 82 ± 1...
January 1, 2018: Phlebology
Won Kyu Choi, Christopher R Bailey, Jan Fritz, Clifford R Weiss
Low-flow vascular malformations are congenital lesions that can occur throughout the body. Treatment of these lesions is indicated to ameliorate pain, cosmetic disfigurement, and functional impairment. The first-line treatment of low-flow vascular malformations is percutaneous sclerotherapy. Traditionally, sclerotherapy is performed with a combination of ultrasound and fluoroscopy. However, malformations that are deep in the abdomen and pelvis or are obscured by overlying fascia or scar may be difficult to be visualized with ultrasound and fluoroscopy...
June 2018: Topics in Magnetic Resonance Imaging: TMRI
Benjamin D Schultz, Rachel Gray, Denis Knobel, Neil Tanna, Dhave Setabutr, Jeffrey A Cheng, Rafael Ortiz, Nicholas Bastidas
OBJECTIVE: Vascular malformations (VMs) in the head and neck region often cause esthetic as well as functional problems for patients. Intramuscular VMs (IVM), such as those in the masseter, can cause severe facial asymmetry and typically are excised transcutaneously to facilitate wide exposure and safe dissection from the facial nerve. This requires extensive dissection, prolonged healing, and can lead to suboptimal facial scarring. METHODS: We describe the technique of resecting large IVMs of the masseter muscle in 3 patients using an entirely intraoral approach with continuous nerve monitoring and without visible facial scarring or secondary deformity...
May 31, 2018: Journal of Craniofacial Surgery
Giuseppe Bianchini, Daniele Camilli, Sergio Furgiuele
PURPOSE: Multiple treatment options have been described for intramuscular venous malformations (VMs) of the limbs. At the current time, there are no clear management guidelines. The aim was to evaluate efficacy and safety of sclerotherapy in this type of VMs. MATERIALS AND METHODS: This is a single-center, retrospective review of patients treated for extremity intramuscular VMs between January 2013 and June 2017. The primary outcomes were the improvement of symptoms self-assessed by questionnaires, and the reduction in VM size measured by magnetic resonance (MRI)...
May 30, 2018: Cardiovascular and Interventional Radiology
Charles H Parker, Jeffrey C Leggit
A 31-yr-old soldier presented with an 8-mo history of right prepatellar bursitis with 1-mo history of pain and loss of range of motion. His symptoms did not respond to activity modification, compression, nonsteroidal anti-inflammatory agents, or repeated aspirations with fenestration. After thorough discussion, the soldier and his provider reviewed the literature and found a single case report of intrabursal sclerotherapy in two patients with recalcitrant prepatellar bursitis. After informed consent, the patient wished to proceed with the scelerotherapy...
May 24, 2018: Military Medicine
Jillian Goines, Xian Li, Yuqi Cai, Paula Mobberley-Schuman, Megan Metcalf, Steven J Fishman, Denise M Adams, Adrienne M Hammill, Elisa Boscolo
Vascular malformations are defects caused by the abnormal growth of the vasculature. Among them, venous malformation (VM) is an anomaly characterized by slow-flow vascular lesions with abnormally shaped veins, typically in sponge-like configuration. VMs can expand over years causing disfigurement, obstruction of vital structures, thrombosis, bleeding, and pain. Treatments have been very limited and primarily based on supportive care, compression garments, sclerotherapy, and/or surgical resection. Sirolimus treatment has recently shown efficacy in some patients with complicated vascular anomalies, including VMs...
May 21, 2018: Angiogenesis
Anthony N Hage, Jeffrey Forris Beecham Chick, Ravi N Srinivasa, Jacob J Bundy, Nikunj R Chauhan, Michael Acord, Joseph J Gemmete
Venous malformations are the most common type of congenital vascular malformation. The diagnosis and management of venous malformations may be challenging, as venous malformations may be located anywhere in the body and range from small and superficial to large and extensive lesions. There are many treatment options for venous malformations including systemic targeted drugs, open surgery, sclerotherapy, cryoablation, and laser photocoagulation. This article reviews the natural history, clinical evaluation, imaging diagnosis, and treatment modalities of venous malformations...
June 2018: Techniques in Vascular and Interventional Radiology
Misbah Tahir, Muhammad Anees Mumtaz, Anum Sultan, Jawaid Iqbal, Raza Sayani
Peripheral vascular malformations (PVMs) represent a wide spectrum of vascular abnormalities occurring due to anomalous connections between arteries, veins, capillaries, and lymphatic channels at the microscopic level, in different combinations. They are rare and challenging to treat. Different operators may have different approaches based on their experience and expertise. Sclerotherapy either alone or in combination with embolization has been used as an independent method for the treatment of PVMs. Purpose The aim of this study is to assess the safety and efficacy of sclerotherapy and embolization, with or without surgery, for the treatment of peripheral vascular malformations, based on our approach...
March 16, 2018: Curēus
Nicla Settembre, Mario D'Oria, Lucie DekerlE, Charbel Saba, Zakariyae Bouziane, Serguei Malikov
Venous malformations are the most common slow-flow vascular malformations; they are not prone to volume decrease over time and invasive treatment is usually required. There are two main techniques to address the definitive therapy of these lesions: sclerotherapy and surgical excision, each with its own advantages and disadvantages. We report the case of a 56 year-old man who came to our attention with persistent pain after multiple unsuccessful attempts to treat a large venous malformation located in the area of the right knee...
May 14, 2018: Annals of Vascular Surgery
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