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https://www.readbyqxmd.com/read/29456959/bleomycin-sclerotherapy-in-lymphangiomas-of-head-and-neck-prospective-study-of-8-cases
#1
Prateek Kumar Porwal, K P Dubey, Amit Morey, Harshita Singh, S Pooja, Alokendu Bose
The aim of this study is to evaluate the role of bleomycin as a primary mode of nonsurgical treatment in lymphangiomas of head and neck and study their complications. This is a prospective study of 8 patients diagnosed with lymphangioma of head and neck presenting to ENT department of Tata main Hospital from December 2014 to January 2017. They were clinically and radiologically evaluated and treated with intralesional injection of bleomycin diluted in normal saline. Complete resolution was seen in 62.5% (5/8) of patients, 25% (2/8) had good response while 12...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29447814/spontaneous-retropharyngeal-and-mediastinal-thoracic-duct-cyst-in-an-infant-with-respiratory-distress
#2
Vidur Bhalla, Thomas Schrepfer, Adam McCann, Pamela Nicklaus, Brenton Reading
Thoracic duct cysts (TDC) within the retropharyngeal space and mediastinum are exceedingly rare lesions, with the majority related to trauma or neoplasm. We describe a case of an otherwise healthy 8-month-old boy who presented with severe respiratory distress, which was found to be caused by a large, spontaneous TDC occupying most the retropharyngeal and mediastinal space. To our knowledge, this is the youngest patient to date presenting with TDC. Ultimately, his TDC was completely resolved with sclerotherapy, however the patient's age and size presented unique challenges to his medical management, which we describe below...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29439934/suppressed-networks-of-inflammatory-mediators-characterize-chronic-venous-insufficiency
#3
Ulka Sachdev, Lena Vodovotz, Julie Bitner, Derek Barclay, Ruben Zamora, Jinling Yin, Richard L Simmons, Yoram Vodovotz
OBJECTIVE: Chronic venous insufficiency (CVI) affects 25 million adults in the United States. Little emphasis has been placed on inflammatory changes associated with CVI. We hypothesize that in patients with early to mid-stage benign varicose vein disease, differences in circulating inflammatory mediators will be manifested in blood draining the involved area vs circulating blood in control subjects. METHODS: Patients undergoing either endovenous ablation or sclerotherapy for Clinical, Etiology, Anatomy, and Pathophysiology clinical class 3 to 5 disease underwent phlebotomy from regional veins at the time of the procedure...
February 10, 2018: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29433866/management-of-nonparasitic-splenic-cysts-in-children
#4
Jenine Hassoun, Gezzer Ortega, Lorrie S Burkhalter, Shellie Josephs, Faisal G Qureshi
BACKGROUND: The management of nonparasitic splenic cysts in children is unclear. Options include observation, cystectomy, partial or total splenectomy and percutaneous aspiration with and without sclerotherapy. The aim of this study is to assess the outcomes of these interventions at a children's hospital. MATERIALS AND METHODS: A retrospective review of patients aged <18 y with splenic cysts over 7 y was performed. Demographics, mode of intervention, and outcome data were collected...
March 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29431255/short-term-side-effects-and-patient-reported-outcomes-of-bleomycin-sclerotherapy-in-vascular-malformations
#5
Joana M Mack, Gresham T Richter, David Becton, Omar Salem, Sarah E M Hill, Shelley E Crary
BACKGROUND: Vascular malformations (VM) are congenital lesions that can be debilitating and cause significant aesthetic and functional limitations. The chemotherapeutic agent bleomycin has been utilized as a sclerosant, directly injected percutaneously into the VM. Unfortunately, little is known about the benefits and short-term side effects of bleomycin with intralesional injections. PROCEDURE: An IRB approved, retrospective chart review was performed on patients with VM who had been treated with intralesional bleomycin...
February 12, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29428536/prospective-comparison-of-effect-of-ligation-and-foam-sclerotherapy-with-foam-sclerotherapy-alone-for-varicose-veins
#6
Xin Li, Bo Yang, Xianlun Li, Shiyan Ren
PURPOSE: To compare the efficacy of ligation after foam sclerotherapy (FSL) with foam sclerotherapy (FS) alone for patients with varicose veins prospectively. METHODS: Ninety-four patients with varicose veins underwent foam sclerothrapy alone and eighty-eight patients with varicose veins received ligation after foam sclerotherapy. Patients were followed up at 1, 3, 6 and 12 months after treatment. The postoperative complications were documented prospectively. RESULTS: In comparison with patients underwent FSL, patients treated with FS only had higher incidence of phlebitis within 4 weeks (14...
February 8, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29417264/polidocanol-sclerotherapy-combined-with-transarterial-embolization-using-n-butyl-cyanoacrylate-for-extracranial-arteriovenous-malformations
#7
Akira Kitagawa, Takahiro Yamamoto, Nozomu Matsunaga, Mayako Yamaji, Shuji Ikeda, Yuichiro Izumi, Makiyo Hagihara, Toyohiro Ota, Tsuneo Ishiguchi
PURPOSE: To assess the safety and effectiveness of polidocanol sclerotherapy combined with transarterial embolization using a liquid adhesive agent (n-butyl cyanoacrylate, NBCA) for treatment of extracranial arteriovenous malformations (AVMs). MATERIALS AND METHODS: Twenty-three patients with symptomatic AVMs in the head and neck (6), upper (7) and lower extremity (10) with a mean age of 42 years (range 4-74) treated with polidocanol sclerotherapy were retrospectively assessed...
February 7, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29415296/vascular-anomalies-part-ii-interventional-therapy-of-peripheral-vascular-malformations
#8
René Müller-Wille, Moritz Wildgruber, Maliha Sadick, Walter A Wohlgemuth
BACKGROUND:  The International Society for the Study of Vascular Anomalies (ISSVA) categorizes vascular anomalies into vascular tumors and vascular malformations. Vascular malformations are further divided into slow-flow (venous, lymphatic, and capillary malformation) and fast-flow malformations (arteriovenous malformation and arteriovenous fistula). This interdisciplinary classification has therapeutic implications. METHODS:  The objective of this article is to provide concise information about the current terminology and treatment strategies of peripheral vascular malformations, based on the currently available literature, with a focus on interventional therapy of venous malformations (VM), lymphatic malformations (LM), arteriovenous malformations (AVM) and arteriovenous fistulae (AVF)...
February 7, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29414196/percutaneous-sclerotherapy-for-giant%C3%A2-symptomatic-liver-hemangiomas-a%C3%A2-pilot-study
#9
Niloofar Ayoobi Yazdi, Habibollah Dashti, Nasim Batavani, Ali Borhani, Majid Shakiba, Hadi Rokni Yazdi
This single-center prospective trial evaluated the safety and efficacy of percutaneous sclerotherapy for liver hemangiomas in 5 patients (1 man, 4 women; mean age 41.2 y) between 2016 and 2017. All patients were symptomatic (4 abdominal pain; 1 early satiety) and refused surgery. A single session of sclerotherapy with 20 cc mixture of 45 IU. Bleomycin in 10 cc distilled water and 10 cc Lipiodol (Ultra Fluide, Guerbet, France) was performed in all patients, achieving a 45.6%-71.1% lesion volume reduction and a 12...
February 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29409702/telangiectatic-matting-is-associated-with-hypersensitivity-and-a-bleeding-tendency
#10
Pooja Kadam, Jerrick Lim, Ian Paver, David E Connor, Kurosh Parsi
OBJECTIVE: The aim was to investigate the pathogenesis of telangiectatic matting (TM) and identify possible risk factors. METHODS: This study had two parts. The clinical records of consecutive patients were retrospectively analysed to identify risk factors for TM. In the second part, the haemostatic and coagulation profile of the subset of patients with TM were analysed and compared with controls using standard coagulation tests, platelet function and a global assay of coagulation (rotational thromboelastometry, ROTEM)...
February 3, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29402614/tissue-plasminogen-activator-to-treat-a-stroke-after-foam-sclerotherapy-in-a-woman-with-a-patent-foramen-ovale
#11
Kosuke Matsuzono, Naoto Arai, Masayuki Suzuki, Younhee Kim, Tadashi Ozawa, Takafumi Mashiko, Haruo Shimazaki, Reiji Koide, Tohru Matsuura, Shigeru Fujimoto
Although foam sclerotherapy to varicose veins is now a popular treatment because of its high efficacy and safety, some neurologic complications have recently been reported. Presently, the effectiveness and safety of intravenous recombinant tissue-type plasminogen activator therapy to stroke following foam sclerotherapy remain unclear. Here, we report the case of a 68-year-old woman whose ischemic symptoms following foam sclerotherapy were treated by intravenous recombinant tissue-type plasminogen activator...
February 2, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29396791/quality-and-readability-of-online-patient-information-regarding-sclerotherapy-for-venous-malformations
#12
Jonathan H Pass, Amani H Patel, Sam Stuart, Alex M Barnacle, Premal A Patel
BACKGROUND: Patients often use the internet as a source of information about their condition and treatments. However, this information is unregulated and varies in quality. OBJECTIVE: To evaluate the readability and quality of online information for pediatric and adult patients and caregivers regarding sclerotherapy for venous malformations. MATERIALS AND METHODS: "Venous malformation sclerotherapy" was entered into Google, and results were reviewed until 20 sites that satisfied predefined inclusion criteria were identified...
February 2, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29390423/the-use-of-sirolimus-in-the-treatment-of-giant-cystic-lymphangioma-four-case-reports-and-update-of-medical-therapy
#13
Ilaria Amodeo, Mariarosa Colnaghi, Genny Raffaeli, Giacomo Cavallaro, Fabrizio Ciralli, Silvana Gangi, Ernesto Leva, Lorenzo Pignataro, Irene Borzani, Lorenza Pugni, Fabio Mosca
RATIONALE: Lymphatic malformations (LMs) are rare and benign anomalies resulting from the defective embryological development of the primordial lymphatic structures. Due to their permeative growth throughout all tissue layers, treatment is often challenging. Small asymptomatic lesions can be conservatively managed, while symptomatic lesions require active management. Surgery has been historically considered the treatment of choice, but today less invasive therapeutic options are preferred (sclerotherapy, laser therapy, oral medications)...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29388867/is-catheter-directed-foam-sclerotherapy-more-effective-than-the-usual-foam-sclerotherapy-for-treatment-of-the-great-saphenous-vein
#14
Orsini Camillo
Objective This retrospective study presents the long-term results of catheter-directed foam sclerotherapy of the great saphenous vein. Method From January 2003 to June 2017, 277 patients with varices and great saphenous vein incompetence were treated with echo-guided foam sclerotherapy. Forty-six patients were treated with long-catheters guided by foam sclerotherapy. Foaming was carried out with sodium-tetra-decyl-sulphate. Results Results were examined in the two groups: A (long-catheters) and B (other procedures)...
January 1, 2018: Phlebology
https://www.readbyqxmd.com/read/29386816/aqueous-intralesional-bleomycin-sclerotherapy-in-lymphatic-malformation-our-experience-with-children-and-adult
#15
Ankur Bhatnagar, Vijai Datta Upadhyaya, Basant Kumar, Zafar Neyaz, Ajay Kushwaha
Objectives: Lymphatic malformations (LMs) are aberrant proliferation of sequestrated lymphatic vessels during early embryogenesis and do not communicate directly with the general lymphatic system. The absence of vascular flow is the hallmark of LMs and is usually symptomless apart from painless disfiguring mass with concerns regarding cosmesis. Design: Sclerotherapy has gained prominence as a preferred treatment modality for macrocystic lesions. Here, we present our experience with use of aqueous bleomycin as intralesional sclerosing agent, an economical first-line treatment for macrocystic variant of LMs in children and adults...
July 2017: National Journal of Maxillofacial Surgery
https://www.readbyqxmd.com/read/29383264/acute-duodenal-intramural-hematoma-complicated-by-acute-pancreatitis-a-rare-complication-of-endoscopic-epinephrine-injection-therapy
#16
Emmanuel Ofori, Tagore Sunkara, Eric Then, Febin John, Vinaya Gaduputi
Intramural duodenal hematoma (IDH) is a rare complication in endoscopic management of ulcer hemorrhage. Usually noted in cases of blunt abdominal trauma, non-traumatic IDHs have been reported in individuals on anticoagulation, with blood disorders, pancreatic diseases and in endoscopic procedures such as biopsy, sclerotherapy and argon plasma coagulation. Patients may be asymptomatic or present with acute blood loss anemia, abdominal pain or vomiting. We report a case of an 83-year-old man with melena and syncope who underwent endoscopy for bleeding ulcer control and subsequently developed acute pancreatitis due to an acute IDH...
January 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29381910/somatic-kras-mutation-in-an-infant-with-linear-nevus-sebaceous-syndrome-associated-with-lymphatic-malformations-a-case-report-and-literature-review
#17
Jiang Lihua, Gao Feng, Mao Shanshan, Xu Jialu, Jiang Kewen
RATIONALE: Linear nevus sebaceous syndrome (LNSS) is a rare neurocutaneous syndrome, characterized by nevus sebaceous,central nervous system (CNS), ocular and skeletal abnormalities. The present study describes KRAS somatic mosaic mutation in a case of LNSS with lymphatic malformations (LMs). PATIENT CONCERNS: A 4-month-old female with a clinical diagnosis of LNSS presented with infantile spasms, mental retardation, skull dysplasia, ocular abnormalities, congenital atrial septal defect, and LMs...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29367372/doxycycline-sclerotherapy-for-post-traumatic-inguinal-lymphocele-in-a-child
#18
Amanda W Harrington, John J Tackett, Brendon L Graeber, Robert A Cowles
Lymphoceles are abnormal collections of lymphatic fluid caused by a disruption in the lymphatic channels and leakage of lymph. This most commonly occurs after surgical procedures, but occasionally lymphoceles may be the result of trauma, more commonly penetrating trauma. Lymphoceles resulting from blunt trauma are rare in both adults and children. In the adult population, there are few published case reports, and management principles vary. To date, there are no reports of traumatic lymphoceles in the paediatric population, and therefore there is no precedent for treatment...
January 23, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29352651/catheter-injected-bone-marrow-mesenchymal-stem-cells-induce-efficacious-occlusion-of-arteriovenous-nidus-in-a-swine-model
#19
Joseph Touma, Jianping Dai, Andre Gaston, Marianne Gervais, Eric Allaire
OBJECTIVES: Arteriovenous malformations (AVMs) are complex vascular lesions. Surgical excision is the treatment of choice, but is often not achievable. Embolo-sclerotherapy alone is associated with high recurrence rates. This study tested the hypothesis that seeding hydrogel conditioned bone marrow derived mesenchymatous stem cells (BM-MSCs) in an AVM nidus model induces solid microvascular occlusion through endoluminal tissue growth. METHODS: AVMs were modelled as arteriovenous microvascular nidus, using swine rete mirabile, a plexiform intracranial structure composed of arterial microvessels that extensively anastomose...
January 15, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29336195/is-aspiration-and-sclerotherapy-treatment-for-hydroceles-in-the-aging-male-an-evidence-based-treatment
#20
W St J Taylor, J Cobley, W Mahmalji
Symptomatic hydroceles are commonly treated with surgical repair. They are associated with sexual dysfunction in the aging male. Patients who are not fit for surgery often undergo aspiration and sclerotherapy of the hydrocele. There is a range of sclerosing agents used in the literature. I performed a literature search to assess whether one sclerosant was better than the others. STDS is the sclerosing agent with the best cure rate after a single injection and low side effect rates. The cure rates of sodium tetradecyl sulphate (STDS) after a single aspiration and injection were 76%...
January 16, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
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