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Transaortic valve replacement

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https://www.readbyqxmd.com/read/27914503/rationale-and-design-of-the-transcatheter-aortic-valve-replacement-to-unload-the-left-ventricle-in-patients-with-advanced-heart-failure-tavr-unload-trial
#1
Ernest Spitzer, Nicolas M Van Mieghem, Philippe Pibarot, Rebecca T Hahn, Susheel Kodali, Mathew S Maurer, Tamim M Nazif, Josep Rodés-Cabau, Jean-Michel Paradis, Arie-Pieter Kappetein, Ori Ben-Yehuda, Gerrit-Anne van Es, Faouzi Kallel, William N Anderson, Jan Tijssen, Martin B Leon
BACKGROUND: Coexistence of moderate aortic stenosis (AS) in patients with heart failure (HF) with reduced ejection fraction is not uncommon. Moderate AS increases afterload, whereas pharmacologic reduction of afterload is a pillar of contemporary HF management. HYPOTHESIS: Unloading the left ventricle by reducing the transaortic gradient with transfemoral transcatheter aortic valve replacement (TAVR) may improve clinical outcomes in patients with moderate AS and HF with reduced ejection fraction...
December 2016: American Heart Journal
https://www.readbyqxmd.com/read/27884356/direct-comparison-of-feasibility-and-safety-of-transfemoral-versus-transaortic%C3%A2-versus-transapical-transcatheter-aortic%C3%A2-valve-replacement
#2
Takahide Arai, Mauro Romano, Thierry Lefèvre, Thomas Hovasse, Arnaud Farge, Daniel Le Houerou, Kentaro Hayashida, Yusuke Watanabe, Philippe Garot, Hakim Benamer, Thierry Unterseeh, Erik Bouvier, Marie-Claude Morice, Bernard Chevalier
OBJECTIVES: The aim of this study was to compare outcomes among transfemoral (TF), transaortic (TAo), and transapical (TA) transcatheter aortic valve replacement (TAVR). BACKGROUND: Very few studies have investigated the differences among TF, TAo, and TA TAVR in terms of safety and feasibility. METHODS: Between January 2011 and December 2014, 467 consecutive cases of TF TAVR, 289 cases of TAo TAVR, and 42 cases of TA TAVR were analyzed. Baseline characteristics, procedural characteristics, and outcomes were compared between TF and TAo and between TAo and TA approaches...
November 28, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27879530/transaortic-edge-to-edge-repair-for-functional-mitral-regurgitation-during-aortic-valve-replacement-a-13-year-experience
#3
Christos G Mihos, Maiteder Larrauri-Reyes, Judy Hung, Orlando Santana
OBJECTIVE: The study evaluated the feasibility of a transaortic edge-to-edge mitral valve repair (Alfieri stitch) for moderate or greater (≥2+) functional mitral regurgitation (MR) in high-risk patients undergoing aortic valve replacement. METHODS: We retrospectively evaluated 40 consecutive patients who underwent aortic valve replacement combined with a transaortic edge-to-edge mitral valve repair for 2+ or greater functional MR, between February 2002 and April 2015...
November 22, 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27765175/learning-alternative-access-approaches-for-transcatheter-aortic-valve-replacement-implications-for-new-transcatheter-aortic-valve%C3%A2-replacement-centers
#4
Matthew C Henn, Thomas Percival, Alan Zajarias, Spencer J Melby, Brian R Lindman, Nishath Quader, Ralph J Damiano, Marc R Moon, John M Lasala, Ravinder S Rao, Jennifer Bell, Marci S Damiano, Hersh S Maniar
BACKGROUND: Smaller transcatheter aortic valve replacement (TAVR) delivery systems have increased the number of patients eligible for transfemoral procedures while decreasing the need for transaortic (TAo) or transapical (TA) access. As a result, newer TAVR centers are likely to have less exposure to these alternative access techniques, making it harder to achieve proficiency. The purpose of this study was to evaluate the learning curve for TAVR approaches and compare perioperative outcomes...
October 17, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27753861/br-02-1-management-of-hypertension-in-severe-aortic-stenosis
#5
Yong-Jin Kim
Aortic stenosis (AS) is a common valve disease, affecting nearly 5% of elderly individuals. Because most common etiology of AS is degenerative valve disease, hypertension (HT) is not rare in patients with AS. It was reported that more than 30% of patients with AS had systemic hypertension. Therefore, management of hypertension is an important issue for these patients. There are several effects of combined AS and HT. First, HT increases hemodynamic load of left ventricle and peak systolic left ventricular wall stress...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27712776/late-outcomes-of-transcatheter-aortic-valve-replacement-in-high-risk-patients-the-france-2-registry
#6
Martine Gilard, Hélène Eltchaninoff, Patrick Donzeau-Gouge, Karine Chevreul, Jean Fajadet, Pascal Leprince, Alain Leguerrier, Michel Lievre, Alain Prat, Emmanuel Teiger, Thierry Lefevre, Didier Tchetche, Didier Carrié, Dominique Himbert, Bernard Albat, Alain Cribier, Arnaud Sudre, Didier Blanchard, Gilles Rioufol, Frederic Collet, Remi Houel, Pierre Dos Santos, Nicolas Meneveau, Said Ghostine, Thibaut Manigold, Philippe Guyon, Dominique Grisoli, Herve Le Breton, Stephane Delpine, Romain Didier, Xavier Favereau, Geraud Souteyrand, Patrick Ohlmann, Vincent Doisy, Gilles Grollier, Antoine Gommeaux, Jean-Philippe Claudel, Francois Bourlon, Bernard Bertrand, Marc Laskar, Bernard Iung
BACKGROUND: Transcatheter aortic valve replacement (TAVR) has revolutionized management of high-risk patients with severe aortic stenosis. However, survival and the incidence of severe complications have been assessed in relatively small populations and/or with limited follow-up. OBJECTIVES: This report details late clinical outcome and its determinants in the FRANCE-2 (FRench Aortic National CoreValve and Edwards) registry. METHODS: The FRANCE-2 registry prospectively included all TAVRs performed in France...
October 11, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27687190/mitral-regurgitation-in-patients-with-hypertrophic-obstructive-cardiomyopathy-implications-for-concomitant-valve-procedures
#7
Joon Hwa Hong, Hartzell V Schaff, Rick A Nishimura, Martin D Abel, Joseph A Dearani, Zhuo Li, Steve R Ommen
BACKGROUND: Incidence and outcome of mitral valve (MV) surgery are unknown in patients with hypertrophic obstructive cardiomyopathy (HOCM) undergoing extended transaortic septal myectomy. OBJECTIVES: This study sought to define indications and suitable operative strategy for mitral regurgitation (MR) in patients with HOCM. METHODS: A total of 2,107 septal myectomy operations performed in adults from January 1993 to May 2014 at Mayo Clinic in Rochester, Minnesota, were retrospectively reviewed...
October 4, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27643098/br-02-1-management-of-hypertension-in-severe-aortic-stenosis
#8
Yong-Jin Kim
Aortic stenosis (AS) is a common valve disease, affecting nearly 5% of elderly individuals. Because most common etiology of AS is degenerative valve disease, hypertension (HT) is not rare in patients with AS. It was reported that more than 30% of patients with AS had systemic hypertension. Therefore, management of hypertension is an important issue for these patients. There are several effects of combined AS and HT. First, HT increases hemodynamic load of left ventricle and peak systolic left ventricular wall stress...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27641297/management-of-small-aortic-annulus-in-the-era-of-sutureless-valves-a-comparative-study-among-different-biological-options
#9
Aly Ghoneim, Ismail Bouhout, Philippe Demers, Amine Mazine, Mary Francispillai, Ismail El-Hamamsy, Michel Carrier, Yoan Lamarche, Denis Bouchard
OBJECTIVE: Aortic valve replacement (AVR) in patients with a small aortic annulus is a challenging problem. The objective of this study was to compare 4 surgical approaches in terms of hemodynamics and perioperative outcomes. METHODS: A retrospective single-center study included 351 consecutive patients with a small aortic annulus (≤21 mm) who underwent aortic valve surgery between January 2007 and December 2014. Surgical techniques included standard AVR in 259 (74%) patients, aortic root enlargement in 20 (6%), implantation of a stentless bioprosthesis in 23 (6%), and sutureless AVR in 49 (13%)...
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27623017/surgery-for-mitral-regurgitation-in-patients-with-aortic-root-aneurysm-transaortic-or-transseptal-approach
#10
Wen-Jian Jiang, Wei-Guo Ma, Xiao-Long Wang, Yu-Yong Liu, Jun-Ming Zhu, Li-Zhong Sun, Hong-Jia Zhang
OBJECTIVE: Mitral regurgitation is common in patients with aortic root aneurysm. Mitral valve repair (MVP) or replacement (MVR) can be performed for these patients through either a transverse aortotomy (TA) or transseptal approach (TS). This study sought to compare the early outcomes of mitral valve surgery through the TA and TS approaches and decide which is optimal for this subset of patients. METHODS: Between March 2013 and April 2015, we operated on 99 patients (81 males, 81...
November 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27609347/early-prediction-of-acute-kidney-injury-after-transapical-and-transaortic-aortic-valve-implantation-with-urinary-g1-cell-cycle-arrest-biomarkers
#11
Fabian Dusse, Michaela Edayadiyil-Dudásova, Matthias Thielmann, Daniel Wendt, Philipp Kahlert, Ender Demircioglu, Heinz Jakob, Simon T Schaefer, Kevin Pilarczyk
BACKGROUND: Acute kidney injury (AKI) is a common complication following transcatheter aortic valve implantation (TAVI) leading to increased mortality and morbidity. Urinary G1 cell cycle arrest proteins TIMP-2 and IGFBP7 have recently been suggested as sensitive biomarkers for early detection of AKI in critically ill patients. However, the precise role of urinary TIMP-2 and IGFBP7 in patients undergoing TAVI is unknown. METHODS: In a prospective observational trial, 40 patients undergoing TAVI (either transaortic or transapical) were enrolled...
September 8, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27609260/intentional-laceration-of-the-anterior-mitral-valve-leaflet-to-prevent-left-ventricular-outflow-tract-obstruction-during-transcatheter-mitral%C3%A2-valve-replacement-pre-clinical-findings
#12
Jaffar M Khan, Toby Rogers, William H Schenke, Jonathan R Mazal, Anthony Z Faranesh, Adam B Greenbaum, Vasilis C Babaliaros, Marcus Y Chen, Robert J Lederman
OBJECTIVES: The authors propose a novel transcatheter transection of the anterior mitral leaflet to prevent iatrogenic left ventricular outflow tract (LVOT) obstruction during transcatheter mitral valve replacement (TMVR). BACKGROUND: LVOT obstruction is a life-threatening complication of TMVR caused by septal displacement of the anterior mitral leaflet. METHODS: In vivo procedures in swine were guided by biplane x-ray fluoroscopy and intracardiac echocardiography...
September 12, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27609257/the-future-of-transaortic-transcatheter-aortic-valve-replacement
#13
EDITORIAL
Vinod H Thourani, Jessica Forcillo
No abstract text is available yet for this article.
September 12, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27609256/transcatheter-aortic-valve-replacement-using-transaortic-access-experience-from%C3%A2-the-multicenter-multinational-prospective-route-registry
#14
Vinayak Bapat, Derk Frank, Ricardo Cocchieri, Dariusz Jagielak, Nikolaos Bonaros, Marco Aiello, Joel Lapeze, Mika Laine, Sidney Chocron, Douglas Muir, Walter Eichinger, Matthias Thielmann, Louis Labrousse, Kjell Arne Rein, Jean-Philippe Verhoye, Gino Gerosa, Hardy Baumbach, Peter Bramlage, Cornelia Deutsch, Martin Thoenes, Mauro Romano
OBJECTIVES: The Registry of the Utilization of the TAo-TAVR approach using the Edwards SAPIEN Valve (ROUTE) was established to assess the effectiveness and safety of the use of transaortic (TAo) access for transcatheter aortic valve replacement (TAVR) procedures (NCT01991431). BACKGROUND: TAVR represents an alternative to surgical valve replacement in high-risk patients. Whereas the transfemoral access route is used commonly as the first-line approach, transapical access is an option for patients not suitable for transfemoral treatment mainly due to anatomic conditions...
September 12, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27577965/embolic-protection-in-patients-undergoing-transaortic-transcatheter-aortic-valve-replacement-initial-experience-with-the-triguard-hdh-embolic-deflection-device
#15
Francisco Campelo-Parada, Ander Regueiro, Eric Dumont, Robert DeLarochellière, Jean-Michel Paradis, Siamak Mohammadi, Daniel Doyle, Josep Rodés-Cabau
BACKGROUND: Stroke remains one of the most worrisome complications following transcatheter aortic valve replacement (TAVR). This pilot study evaluates the safety, feasibility, and exploratory efficacy of the TriGuard HDH embolic deflection device (Keystone Heart Ltd., Caesarea, Israel) in patients undergoing transaortic TAVR. METHODS: A total of 10 patients (median age: 81 years, STS score: 9.6 ± 5.6%) undergoing transaortic TAVR were included. All 30-day events were recorded and defined according to Valve Academic Research Consortium-2 criteria...
October 2016: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/27572827/influence-of-same-day-admission-on-outcomes-following-transcatheter-aortic-valve-replacement
#16
Samir V Patel, Sunny Jhamnani, Palak Patel, Rajesh Sonani, Chirag Savani, Nilay Patel, Nileshkumar J Patel, Sidakpal S Panaich, Mihir Patel, Schreiber Theodore, Cindy Grines, Apurva O Badheka
BACKGROUND: Since elective transcatheter aortic valve replacements (TAVRs) can be performed on the day of admission, i.e., Day 0, or on the next day of admission, i.e., Day 1, we sought to investigate if there is an advantage to either approach. METHODS: We performed a retrospective cohort study, using the Healthcare Cost and Utilization Project's Nationwide Inpatient Sample database of 2012 and identified subjects undergoing endovascular (Transfemoral/Transaortic) TAVRs using the ICD-9-CM procedure code of 35...
October 2016: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/27545664/effectiveness-of-alcohol-septal-ablation-versus-transaortic-extended-myectomy-in-hypertrophic-cardiomyopathy-with-midventricular-obstruction
#17
Yin-Jian Yang, Chao-Mei Fan, Jin-Qing Yuan, Shui-Yun Wang, Yun-Hu Song, Shu-Bin Qiao, Shi-Jie You, Zhi-Min Wang, Fu-Jian Duan, Yi-Shi Li
OBJECTIVES: Investigate the effectiveness of alcohol septal ablation (ASA) and transaortic extended myectomy (TEM) in hypertrophic cardiomyopathy (HCM) with midventricular obstruction (MVO). BACKGROUND: MVO is less common than subaortic obstruction. Data on the effectiveness of ASA and TEM in MVO are lacking. METHODS: The clinical profiles of 22 patients undergoing ASA and 37 patients undergoing TEM were compared. No patient had apical aneurysm, abnormal chordae, mitral valve replacement or repair...
December 2016: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/27534978/transcatheter-aortic-valve-implantation-in-patients-with-small-aortic-annuli-using-a-20%C3%A2-mm-balloon-expanding-valve
#18
Rishi Puri, Jonathan Byrne, Ralf Muller, Hardy Baumbach, Helene Eltchaninoff, Simon Redwood, Asim Cheema, Christophe Dubois, Leo Ihlberg, Harindra C Wijeysundera, Alfredo Cerillo, Matthias Götberg, Kaj Erik Klaaborg, Marc Pelletier, Roberto Blanco-Mata, Richard Edwards, Caterina Gandolfo, Douglas Muir, Francesco Meucci, Jan-Malte Sinning, Pieter Stella, Verena Veulemans, Marko Virtanen, Ander Regueiro, Martin Thoenes, Philippe Pibarot, Emilie Pelletier-Beaumont, Josep Rodés-Cabau
BACKGROUND: While transcatheter aortic valve implantation (TAVI) is established for treating high-operative risk surgical aortic valve replacement candidates, until recently the smallest transcatheter heart valve (THV) measured 23 mm, posing greater risk for annular rupture and THV failure in patients with aortic stenosis (AS) with small aortic annuli (≤20 mm). OBJECTIVES: In the setting of a multicentre registry, we report on the safety, efficacy and early clinical outcomes of the SAPIEN XT 20 mm balloon-expanding THV...
August 17, 2016: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/27502129/-transcatheter-aortic-valve-replacement-the-new-era-new-opportunity-and-new-challenge-of-cardiac-surgery
#19
L Wei, Y Yang, C S Wang, H Liu
Conventional surgical aortic valve replacement is still the current "gold standard" in treatment of aortic valve disease, but part of the high-risk elder patients couldn't tolerate the surgical trauma. Now those people could receive timely and effective treatment with the application of transcatheter aortic valve replacement, and the related guidelines have been published in recent years. With its wide use in recent 10 years, different implantation systems, such as SAPIEN, CoreValve, Lotus, ACURATE neo, have been gradually improved and provened in several large clinical trials...
August 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27498901/early-results-of-simultaneous-transaortic-transcatheter-aortic-valve-implantation-and-total-arterial-off-pump-coronary-artery-revascularization-in-high-risk-patients
#20
Junjiro Kobayashi, Yusuke Shimahara, Tomoyuki Fujita, Hideaki Kanzaki, Makoto Amaki, Hiroki Hata, Yuta Kume, Kizuku Yamashita, Atsushi Okada
BACKGROUND: Transcatheter aortic valve implantation (TAVI) has become an alternative procedure for treating aortic stenosis (AS) in patients with advanced age and severe comorbidities. Ischemic heart disease (IHD) is present with AS in 40-50% of patients with typical angina. Considering the high operative mortality and morbidity rates in these patients, hybrid TAVI and off-pump CABG (OPCAB) have become realistic treatment options. METHODS AND RESULTS: Between August 2014 and November 2015, 12 patients were evaluated for simultaneous TAVI and OPCAB...
August 25, 2016: Circulation Journal: Official Journal of the Japanese Circulation Society
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