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https://www.readbyqxmd.com/read/28100562/healthcare-organisation-and-delivery-for-people-with-dementia-and-comorbidity-a-qualitative-study-exploring-the-views-of-patients-carers-and-professionals
#1
Frances Bunn, Anne-Marie Burn, Louise Robinson, Marie Poole, Greta Rait, Carol Brayne, Johan Schoeman, Sam Norton, Claire Goodman
OBJECTIVES: People living with dementia (PLWD) have a high prevalence of comorbidty. The aim of this study was to explore the impact of dementia on access to non-dementia services and identify ways of improving service delivery for this population. DESIGN: Qualitative study involving interviews and focus groups. Thematic content analysis was informed by theories of continuity of care and access to care. SETTING: Primary and secondary care in the South and North East of England...
January 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28093647/evaluation-of-particle-size-influence-on-proximate-composition-physicochemical-techno-functional-and-physio-functional-properties-of-flours-obtained-from-persimmon-diospyros-kaki-trumb-coproducts
#2
Raquel Lucas-González, Manuel Viuda-Martos, José Ángel Pérez-Álvarez, Juana Fernández-López
The aim of the work was to study the influence of particle size in the composition, physicochemical, techno-functional and physio-functional properties of two flours obtained from persimmon (Diospyros kaki Trumb. cvs. 'Rojo Brillante' (RBF) and 'Triump' (THF) coproducts. The cultivar (RBF and THF) and particle size significantly affected all parameters under study, although depending on the evaluated property, only one of these effects predominated. Carbohydrates (38.07-46.98 g/100 g) and total dietary fiber (32...
January 16, 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/28053236/cd8-t-cells-that-coexpress-ror%C3%AE-t-and-t-bet-are-functionally-impaired-and-expand-in-patients-with-distal-bile-duct-cancer
#3
Stalin Chellappa, Harald Hugenschmidt, Morten Hagness, Saranya Subramani, Espen Melum, Pål Dag Line, Knut-Jørgen Labori, Gro Wiedswang, Kjetil Taskén, Einar Martin Aandahl
CD8(+) T cells that express retinoic acid-related orphan receptor (ROR)γt (TC17 cells) have been shown to promote procarcinogenic inflammation and contribute to a tolerogenic microenvironment in tumors. We investigated their phenotype and functional properties in relationship to the pathogenesis of human distal bile duct cancer (DBDC). DBDC patients had an elevated level of type 17 immune responses and the frequency of CD8(+)RORγt(+) T cells (TC17 cells) was increased in peripheral blood. The CD8(+)RORγt(+) T cells represented a highly activated subset and produced IL-17A in equal amount as CD4(+)RORγt(+) T cells (TH17 cells)...
January 4, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28004884/fermentation-of-glycerol-by-anaerobium-acetethylicum-and-its-potential-use-in-biofuel-production
#4
Yogita Patil, Madan Junghare, Nicolai Müller
Growth of biodiesel industries resulted in increased coproduction of crude glycerol which is therefore becoming a waste product instead of a valuable 'coproduct'. Glycerol can be used for the production of valuable chemicals, e.g. biofuels, to reduce glycerol waste disposal. In this study, a novel bacterial strain is described which converts glycerol mainly to ethanol and hydrogen with very little amounts of acetate, formate and 1,2-propanediol as coproducts. The bacterium offers certain advantages over previously studied glycerol-fermenting microorganisms...
December 22, 2016: Microbial Biotechnology
https://www.readbyqxmd.com/read/27992794/a-comparison-between-corn-and-grain-sorghum-fermentation-rates-distillers-dried-grains-with-solubles-composition-and-lipid-profiles
#5
David J Johnston, Robert A Moreau
The aim of this study was to determine if the compositional difference between grain sorghum and corn impact ethanol yields and coproduct value when grain sorghum is incorporated into existing corn ethanol facilities. Fermentation properties of corn and grain sorghum were compared utilizing two fermentation systems (conventional thermal starch liquefaction and native starch hydrolysis). Fermentation results indicated that protease addition influenced the fermentation rate and yield for grain sorghum, improving yields by 1-2% over non-protease treated fermentations...
December 5, 2016: Bioresource Technology
https://www.readbyqxmd.com/read/27940633/supporting-underserved-patients-with-their-medicines-a-study-protocol-for-a-patient-professional-coproduced-education-intervention-for-community-pharmacy-staff-to-improve-the-provision-and-delivery-of-medicine-use-reviews-murs
#6
Asam Latif, Kristian Pollock, Claire Anderson, Justin Waring, Josie Solomon, Li-Chia Chen, Emma Anderson, Sulma Gulzar, Nasa Abbasi, Heather Wharrad
INTRODUCTION: Community pharmacy increasingly features in global strategies to modernise the delivery of primary healthcare. Medicine Use Reviews (MURs) form part of the English Government's medicines management strategy to improve adherence and reduce medicine waste. MURs provide space for patient-pharmacist dialogue to discuss the well-known problems patients experience with medicine taking. However, 'underserved' communities (eg, black and minority ethnic communities, people with mental illness), who may benefit the most, may not receive this support...
December 9, 2016: BMJ Open
https://www.readbyqxmd.com/read/27927969/combined-single-cell-measurement-of-cytokine-mrna-and-protein-identifies-t-cells-with-persistent-effector-function
#7
Benoit P Nicolet, Aurelie Guislain, Monika C Wolkers
Effective T cell responses entail the coproduction of IFN-γ, TNF-α, and IL-2. Cytokine production is determined by transcriptional and posttranscriptional events. However, increased transcript levels do not always translate into protein production, and therefore simultaneous transcripts and protein measurement are essential for the appropriate analysis of T cell responses. In this study, we optimized flow cytometry-based fluorescence in situ hybridization (Flow-FISH) for IFN-γ to multicolor flow cytometry that allows for single-cell measurement of mRNA and protein levels...
December 7, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27923610/algal-polycultures-enhance-coproduct-recycling-from-hydrothermal-liquefaction
#8
Casey M Godwin, David C Hietala, Aubrey R Lashaway, Anita Narwani, Phillip E Savage, Bradley J Cardinale
The aim of this study was to determine if polycultures of algae could enhance tolerance to aqueous-phase coproduct (ACP) from hydrothermal liquefaction (HTL) of algal biomass to produce biocrude. The growth of algal monocultures and polycultures was characterized across a range ACP concentrations and sources. All of the monocultures were either killed or inhibited by 2% ACP, but polycultures of the same species were viable at up to 10%. The addition of ACP increased the growth rate (up to 25%) and biomass production (53%) of polycultures, several of which were more productive in ACP than any monoculture was in the presence or absence of ACP...
January 2017: Bioresource Technology
https://www.readbyqxmd.com/read/27898877/effects-of-full-fat-or-defatted-rice-bran-on-growth-performance-and-blood-characteristics-of-weanling-pigs
#9
G A Casas, H H Stein
The objective of this experiment was to determine the effect of increased concentrations of full fat rice bran (FFRB) or defatted rice bran (DFRB) in diets without or with supplementation of an exogenous xylanase on growth performance and blood characteristics in weanling pigs. A total of 532 pigs (9.3 ± 0.5 kg initial BW) were allotted to 14 diets in 4 blocks and 8 replicate pens per diet in a randomized complete block design. There were 4 or 5 pigs per pen. A basal diet containing corn, soybean meal, and whey powder and 6 diets containing corn, soybean meal, whey powder, and 10, 20, or 30% FFRB or 10, 20, or 30% DFRB were used...
October 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27880986/nutrients-amino-acid-fatty-acid-and-non-starch-polysaccharide-profile-and-in-vitro-digestibility-of-macadamia-nut-cake-in-swine
#10
Utsav P Tiwari, Rajesh Jha
The highly variable cost and limited availability of conventional feedstuffs make it imperative to explore alternative feedstuffs to be used in swine. Macadamia nut cake (MNC), a coproduct of the macadamia nut oil industry, has not been well studied. MNC was analyzed for its nutrient profile, gross energy (GE), fibers, amino acids and fatty acids content. Dry matter (DM) and GE digestibility of MNC in swine was determined using an in vitro model. On a DM basis, ash, crude protein, ether extract, NDF, ADF, lignin and GE were found to be 3...
November 23, 2016: Animal Science Journal, Nihon Chikusan Gakkaihō
https://www.readbyqxmd.com/read/27872964/toward-sustainable-amino-acid-production
#11
Yoshihiro Usuda, Yoshihiko Hara, Hiroyuki Kojima
Because the global amino acid production industry has been growing steadily and is expected to grow even more in the future, efficient production by fermentation is of great importance from economic and sustainability viewpoints. Many systems biology technologies, such as genome breeding, omics analysis, metabolic flux analysis, and metabolic simulation, have been employed for the improvement of amino acid-producing strains of bacteria. Synthetic biological approaches have recently been applied to strain development...
November 22, 2016: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/27867207/purification-of-bioactive-lipopeptides-produced-by-bacillus-subtilis-strain-bia
#12
Muaaz Alajlani, Abid Shiekh, Shahida Hasnain, Adelheid Brantner
Bacillus subtilis strain BIA was used for the production of bioactive lipopeptides. Different extraction and purification methods were assayed as liquid-liquid extraction, and acid and ammonium sulfate precipitation followed by TLC, SPE, and gel filtration. Active fractions were further purified using RP-HPLC. The molecular mass of the purified product from HPLC was determined through Tris-Tricine SDS-PAGE and MALDI-TOF-MS. The results revealed that Bacillus subtilis strain BIA produced surfactin and iturin like compounds...
2016: Chromatographia
https://www.readbyqxmd.com/read/27833653/valorization-of-lignin-and-cellulose-in-acid-steam-exploded-corn-stover-by-a-moderate-alkaline-ethanol-post-treatment-based-on-an-integrated-biorefinery-concept
#13
Sheng Yang, Yue Zhang, Wen Yue, Wei Wang, Yun-Yan Wang, Tong-Qi Yuan, Run-Cang Sun
BACKGROUND: Due to the unsustainable consumption of fossil resources, great efforts have been made to convert lignocellulose into bioethanol and commodity organic compounds through biological methods. The conversion of cellulose is impeded by the compactness of plant cell wall matrix and crystalline structure of the native cellulose. Therefore, appropriate pretreatment and even post-treatment are indispensable to overcome this problem. Additionally, an adequate utilization of coproduct lignin will be important for improving the economic viability of modern biorefinery industries...
2016: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/27813679/the-role-of-biofuels-coproducts-in-feeding-the-world-sustainably
#14
Gerald C Shurson
One of the grand challenges facing our society today is finding solutions for feeding the world sustainably. The food-versus-fuel debate is a controversy embedded in this challenge, involving the trade-offs of using grains and oilseeds for biofuels production versus animal feed and human food. However, only 6% of total global grain produced is used to produce ethanol. Furthermore, biofuels coproducts contribute to sustainability of food production because only 1% to 2.5% of the overall energy efficiency is lost from converting crops into biofuels and animal feed, and approximately one-third of the corn used to produce ethanol is recovered as feed coproducts...
October 24, 2016: Annual Review of Animal Biosciences
https://www.readbyqxmd.com/read/27801788/molecular-dynamic-studies-of-the-complex-polyethylenimine-and-glucose-oxidase
#15
Beata Szefler, Mircea V Diudea, Mihai V Putz, Ireneusz P Grudzinski
Glucose oxidase (GOx) is an enzyme produced by Aspergillus, Penicillium and other fungi species. It catalyzes the oxidation of β-d-glucose (by the molecular oxygen or other molecules, like quinones, in a higher oxidation state) to form d-glucono-1,5-lactone, which hydrolyses spontaneously to produce gluconic acid. A coproduct of this enzymatic reaction is hydrogen peroxide (H₂O₂). GOx has found several commercial applications in chemical and pharmaceutical industries including novel biosensors that use the immobilized enzyme on different nanomaterials and/or polymers such as polyethylenimine (PEI)...
October 27, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27789779/what-works-for-wellbeing-in-culture-and-sport-report-of-a-delphi-process-to-support-coproduction-and-establish-principles-and-parameters-of-an-evidence-review
#16
REVIEW
Norma Daykin, Louise Mansfield, Annette Payne, Tess Kay, Catherine Meads, Giorgia D'Innocenzo, Adele Burnett, Paul Dolan, Guy Julier, Louise Longworth, Alan Tomlinson, Stefano Testoni, Christina Victor
AIMS: There is a growing recognition of the ways in which culture and sport can contribute to wellbeing. A strong evidence base is needed to support innovative service development and a 3-year research programme is being undertaken to capture best evidence of wellbeing impacts and outcomes of cultural and sporting activities in order to inform UK policy and practice. This article provides an overview of methods and findings from an initial coproduction process with key stakeholders that sought to explore and agree principles and parameters of the evidence review for culture, sport and wellbeing (CSW)...
October 27, 2016: Perspectives in Public Health
https://www.readbyqxmd.com/read/27774376/sungas-instead-of-syngas-efficient-coproduction-of-co-and-h2-with-a-single-beam-of-sunlight
#17
Fang-Fang Li, Jason Lau, Stuart Licht
The electrolytic coproduction of CO and H2 is achieved from air, water, and a single beam of sunlight rather than from fossil fuels. H2 and CO cosynthesis is driven by a single concentrator photovoltaic to simultaneously drive molten hydroxide and molten carbonate electrolyses. The carbon neutral process captures carbon without the need for the preconcentration of atmospheric carbon dioxide.
November 2015: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://www.readbyqxmd.com/read/27757415/monolignol-ferulate-conjugates-are-naturally-incorporated-into-plant-lignins
#18
Steven D Karlen, Chengcheng Zhang, Matthew L Peck, Rebecca A Smith, Dharshana Padmakshan, Kate E Helmich, Heather C A Free, Seonghee Lee, Bronwen G Smith, Fachuang Lu, John C Sedbrook, Richard Sibout, John H Grabber, Troy M Runge, Kirankumar S Mysore, Philip J Harris, Laura E Bartley, John Ralph
Angiosperms represent most of the terrestrial plants and are the primary research focus for the conversion of biomass to liquid fuels and coproducts. Lignin limits our access to fibers and represents a large fraction of the chemical energy stored in plant cell walls. Recently, the incorporation of monolignol ferulates into lignin polymers was accomplished via the engineering of an exotic transferase into commercially relevant poplar. We report that various angiosperm species might have convergently evolved to natively produce lignins that incorporate monolignol ferulate conjugates...
October 2016: Science Advances
https://www.readbyqxmd.com/read/27594998/erratum-improving-interprofessional-and-coproductive-outcomes-of-care-for-patients-with-chronic-obstructive-pulmonary-disease
#19
(no author information available yet)
[This corrects the article DOI: 10.1136/bmjquality.u210329.w4679.].
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27566521/selective-synthesis-of-human-milk-fat-style-structured-triglycerides-from-microalgal-oil-in-a-microfluidic-reactor-packed-with-immobilized-lipase
#20
Jun Wang, Xi Liu, Xu-Dong Wang, Tao Dong, Xing-Yu Zhao, Dan Zhu, Yi-Yuan Mei, Guo-Hua Wu
Human milk fat-style structured triacylglycerols were produced from microalgal oil in a continuous microfluidic reactor packed with immobilized lipase for the first time. A remarkably high conversion efficiency was demonstrated in the microreactor with reaction time being reduced by 8 times, Michaelis constant decreased 10 times, the lipase reuse times increased 2.25-fold compared to those in a batch reactor. In addition, the content of palmitic acid at sn-2 position (89.0%) and polyunsaturated fatty acids at sn-1, 3 positions (81...
November 2016: Bioresource Technology
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