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https://www.readbyqxmd.com/read/28295383/recovery-of-pectic-hydrocolloids-and-phenolics-from-huanglongbing-related-dropped-citrus-fruit
#1
Randall G Cameron, Hoa K Chau, Arland T Hotchkiss, John A Manthey
BACKGROUND: Citrus preharvest fruit drop, caused by Huanglongbing infection, has increased dramatically concomitant with declining tree health and crop harvest size. This loss of harvestable fruit is damaging to both growers and juice processors. Recovering and converting this fruit to alternative value added products would benefit the citrus industry. Therefore, we have explored the potential for using this fruit as a feedstock in our newly developed pilot scale continuous steam explosion process...
March 12, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28261897/coproduction-of-colicin-v-and-lactic-acid-bacteria-bacteriocins-in-lactococci-and-enterococci-strains-of-biotechnological-interest
#2
S Langa, J L Arqués, M Medina, J M Landete
AIMS: The aim of this study was the coproduction in a single strain of the Gram-negative bacteriocin colicin V with other bacteriocins from lactic acid bacteria. METHODS AND RESULTS: Colicin V was expressed in Lactococcus and Enterococcus strains by replacing the colicin V leader peptide by the leader peptide and promoter of D-alanyl-D-alanine carboxypeptidase from Lactobacillus reuteri CECT925 (pNZ:LR-colV). The antimicrobial activity of colicin V against the indicator organism E...
March 6, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/28261178/evolution-of-anabaenopeptin-peptide-structural-variability-in-the-cyanobacterium-planktothrix
#3
Elisabeth Entfellner, Mark Frei, Guntram Christiansen, Li Deng, Jochen Blom, Rainer Kurmayer
Cyanobacteria are frequently involved in the formation of harmful algal blooms wherein, apart from the toxic microcystins, other groups of bioactive peptides are abundant as well, such as anabaenopeptins (APs). The APs are synthesized nonribosomally as cyclic hexapeptides with various amino acids at the exocyclic position. We investigated the presence and recombination of the AP synthesis gene cluster (apnA-E) through comparing 125 strains of the bloom-forming cyanobacterium Planktothrix spp., which were isolated from numerous shallow and deep water habitats in the temperate and tropical climatic zone...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28243672/a-new-model-of-collaborative-research-experiences-from-one-of-australia-s-nhmrc-partnership-centres-for-better-health
#4
Sonia Wutzke, Sally Redman, Adrian Bauman, Penelope Hawe, Alan Shiell, Sarah Thackway, Andrew Wilson
There is often a disconnection between the creation of evidence and its use in policy and practice. Cross-sectoral, multidisciplinary partnership research, founded on shared governance and coproduction, is considered to be one of the most effective means of overcoming this research-policy-practice disconnect. Similar to a number of funding bodies internationally, Australia's National Health and Medical Research Council has introduced Partnership Centres for Better Health: a scheme explicitly designed to encourage coproduced partnership research...
February 15, 2017: Public Health Research & Practice
https://www.readbyqxmd.com/read/28243668/a-long-term-strategic-approach-to-evidence-generation-and-knowledge-translation-in-nsw-australia
#5
Sarah Thackway, Danielle Campbell, Tina Loppacher
There is a growing body of literature about the barriers to, and enablers of, the use of research evidence in policy and practice. Research funders are in a unique position to influence activities aimed at promoting research use. During the past decade, NSW (New South Wales) Health has systematically built and invested in an integrated population and health services research portfolio made up of different types of investment and policy focuses. Each of these investments has an explicit focus on translation...
February 15, 2017: Public Health Research & Practice
https://www.readbyqxmd.com/read/28238725/functional-and-structural-analysis-of-programmed-c-methylation-in-the-biosynthesis-of-the-fungal-polyketide-citrinin
#6
Philip A Storm, Dominik A Herbst, Timm Maier, Craig A Townsend
Fungal polyketide synthases (PKSs) are large, multidomain enzymes that biosynthesize a wide range of natural products. A hallmark of these megasynthases is the iterative use of catalytic domains to extend and modify a series of enzyme-bound intermediates. A subset of these iterative PKSs (iPKSs) contains a C-methyltransferase (CMeT) domain that adds one or more S-adenosylmethionine (SAM)-derived methyl groups to the carbon framework. Neither the basis by which only specific positions on the growing intermediate are methylated ("programming") nor the mechanism of methylation are well understood...
March 16, 2017: Cell Chemical Biology
https://www.readbyqxmd.com/read/28221926/evaluation-of-selected-nutrients-and-contaminants-in-distillers-grains-from-ethanol-production-in-texas
#7
Kyung-Min Lee, Timothy J Herrman, Lynn Post
This article contains the results of the evaluation of distillers grain (DG) coproducts from different ethanol plants around the United States and supplemented in animal diets in Texas, based on samples analyzed from 2008 to 2014. The samples were assessed for concentration, occurrence, and prevalence of selected nutrients and contaminants. Protein and sulfur contents of DG were largely different between maize and sorghum coproducts, as well as wet distillers grain with solubles (WDGS) and dried distillers grain with solubles (DDGS), indicating a significant effect of grain feedstock and dry grind process stream on DG composition and quality...
September 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28213083/-health-promotion-and-logic-models
#8
Cecile Marie Dupin
The first phase of interventional research in the health of populations is the development of its conceptual basis. Programme logic models are used to describe the way in which the results should be generated. The programme theory is used to develop intermediary objectives and to increase the chances of success of public health actions. This approach requires the coproduction of knowledge between researchers and partners. The teams can benefit from the application of evaluation to the theory in order to clarify the results obtained...
January 2017: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/28209815/whole-genome-sequence-of-a-colombian-acinetobacter-baumannii-strain-a-coproducer-of-oxa-72-and-oxa-255-like-carbapenemases
#9
Sandra Yamile Saavedra, Diego Prada-Cardozo, Verónica Rincón, Hermes Pérez-Cardona, Andrea Melissa Hidalgo, María Nilse González, María T Reguero, Emilia M Valenzuela de Silva, José R Mantilla, Laurent Falquet, Emiliano Barreto-Hernández, Carolina Duarte
Colombian Acinetobacter baumannii strain ST920 was isolated from the sputum of a 68-year-old male patient. This isolate possessed blaOXA-72 and blaOXA-255-like genes. The assembled genome contained 4,104,098 pb and 38.79% G+C content. This is the first case reported of the coproduction (blaOXA-72 and blaOXA-255-like) of carbapenem-hydrolyzing class D β-lactamases (CHDLs) in Acinetobacter baumannii.
February 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28174225/supporting-shared-decision-making-for-older-people-with-multiple-health-and-social-care-needs-a-protocol-for-a-realist-synthesis-to-inform-integrated-care-models
#10
Frances Bunn, Claire Goodman, Jill Manthorpe, Marie-Anne Durand, Isabel Hodkinson, Greta Rait, Paul Millac, Sue L Davies, Bridget Russell, Patricia Wilson
INTRODUCTION: Including the patient or user perspective is a central organising principle of integrated care. Moreover, there is increasing recognition of the importance of strengthening relationships among patients, carers and practitioners, particularly for individuals receiving substantial health and care support, such as those with long-term or multiple conditions. The overall aims of this synthesis are to provide a context-relevant understanding of how models to facilitate shared decision-making (SDM) might work for older people with multiple health and care needs, and how they might be applied to integrated care models...
February 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28144154/occurrence-of-extended-spectrum-and-ampc-%C3%AE-lactamases-in-multiple-drug-resistant-salmonella-isolates-from-clinical-samples-in-lagos-nigeria
#11
K O Akinyemi, Bamidele Abiodun Iwalokun, Akeeb O Bola Oyefolu, C O Fakorede
PURPOSE: Salmonella spp. are important foodborne pathogens exhibiting increasing resistance to antimicrobial drugs. Resistance to broad-spectrum β-lactams, mediated by extended-spectrum β-lactamase (ESBL) and AmpC β-lactamase enzymes is fast spreading and has had negative impacts on the clinical outcomes, particularly on third-generation cephalosporins. This study investigated the carriage of AmpC gene among multidrug-resistant Salmonella spp. from Lagos, Nigeria. METHODS: Forty Salmonella spp...
2017: Infection and Drug Resistance
https://www.readbyqxmd.com/read/28139253/determinants-of-evidence-use-in-public-health-policy-making-results-from-a-study-across-six-eu-countries
#12
Ien van de Goor, Riitta-Maija Hämäläinen, Ahmed Syed, Cathrine Juel Lau, Petru Sandu, Hilde Spitters, Leena Eklund Karlsson, Diana Dulf, Adriana Valente, Tommaso Castellani, Arja R Aro
The knowledge-practice gap in public health is widely known. The importance of using different types of evidence for the development of effective health promotion has also been emphasized. Nevertheless, in practice, intervention decisions are often based on perceived short-term opportunities, lacking the most effective approaches, thus limiting the impact of health promotion strategies. This article focuses on facilitators and barriers in the use of evidence in developing health enhancing physical activity policies...
January 20, 2017: Health Policy
https://www.readbyqxmd.com/read/28128357/multilevel-interaction-of-the-dnak-dnaj-hsp70-hsp40-stress-responsive-chaperone-machine-with-the-central-metabolism
#13
Fréderic Anglès, Marie-Pierre Castanié-Cornet, Nawel Slama, Mickael Dinclaux, Anne-Marie Cirinesi, Jean-Charles Portais, Fabien Létisse, Pierre Genevaux
Networks of molecular chaperones maintain cellular protein homeostasis by acting at nearly every step in the biogenesis of proteins and protein complexes. Herein, we demonstrate that the major chaperone DnaK/HSP70 of the model bacterium Escherichia coli is critical for the proper functioning of the central metabolism and for the cellular response to carbon nutrition changes, either directly or indirectly via the control of the heat-shock response. We identified carbon sources whose utilization was positively or negatively affected by DnaK and isolated several central metabolism genes (among other genes identified in this work) that compensate for the lack of DnaK and/or DnaK/Trigger Factor chaperone functions in vivo...
January 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28125780/tight-binding-of-carboxylate-phosphonate-and-carbamate-anions-to-stoichiometric-cdse-nanocrystals
#14
Peter E Chen, Nicholas C Anderson, Zachariah M Norman, Jonathan S Owen
To completely displace the carboxylate surface ligands from cadmium selenide nanocrystals, oleic acid impurities are first removed using dimethylcadmium or diethylzinc. In addition to metal carboxylate and methane coproducts, reactions with CdMe2 produce surface bound methyl groups (δ = 0.4 ppm, 0.04-0.22 nm(-2)) that photolytically dissociate to methyl radicals and n-doped nanocrystals. Without oleic acid impurities, cadmium carboxylate can be completely displaced from the surface using n-alkylamines (NH2R', R' = n-butyl, n-hexyl, n-octyl) (≤0...
February 16, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28100562/healthcare-organisation-and-delivery-for-people-with-dementia-and-comorbidity-a-qualitative-study-exploring-the-views-of-patients-carers-and-professionals
#15
Frances Bunn, Anne-Marie Burn, Louise Robinson, Marie Poole, Greta Rait, Carol Brayne, Johan Schoeman, Sam Norton, Claire Goodman
OBJECTIVES: People living with dementia (PLWD) have a high prevalence of comorbidty. The aim of this study was to explore the impact of dementia on access to non-dementia services and identify ways of improving service delivery for this population. DESIGN: Qualitative study involving interviews and focus groups. Thematic content analysis was informed by theories of continuity of care and access to care. SETTING: Primary and secondary care in the South and North East of England...
January 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28093647/evaluation-of-particle-size-influence-on-proximate-composition-physicochemical-techno-functional-and-physio-functional-properties-of-flours-obtained-from-persimmon-diospyros-kaki-trumb-coproducts
#16
Raquel Lucas-González, Manuel Viuda-Martos, José Ángel Pérez-Álvarez, Juana Fernández-López
The aim of the work was to study the influence of particle size in the composition, physicochemical, techno-functional and physio-functional properties of two flours obtained from persimmon (Diospyros kaki Trumb. cvs. 'Rojo Brillante' (RBF) and 'Triump' (THF) coproducts. The cultivar (RBF and THF) and particle size significantly affected all parameters under study, although depending on the evaluated property, only one of these effects predominated. Carbohydrates (38.07-46.98 g/100 g) and total dietary fiber (32...
March 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/28053236/cd8-t-cells-that-coexpress-ror%C3%AE-t-and-t-bet-are-functionally-impaired-and-expand-in-patients-with-distal-bile-duct-cancer
#17
Stalin Chellappa, Harald Hugenschmidt, Morten Hagness, Saranya Subramani, Espen Melum, Pål Dag Line, Knut-Jørgen Labori, Gro Wiedswang, Kjetil Taskén, Einar Martin Aandahl
CD8(+) T cells that express retinoic acid-related orphan receptor (ROR)γt (TC17 cells) have been shown to promote procarcinogenic inflammation and contribute to a tolerogenic microenvironment in tumors. We investigated their phenotype and functional properties in relationship to the pathogenesis of human distal bile duct cancer (DBDC). DBDC patients had an elevated level of type 17 immune responses and the frequency of CD8(+)RORγt(+) T cells (TC17 cells) was increased in peripheral blood. The CD8(+)RORγt(+) T cells represented a highly activated subset and produced IL-17A in equal amount as CD4(+)RORγt(+) T cells (TH17 cells)...
January 4, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28004884/fermentation-of-glycerol-by-anaerobium-acetethylicum-and-its-potential-use-in-biofuel-production
#18
Yogita Patil, Madan Junghare, Nicolai Müller
Growth of biodiesel industries resulted in increased coproduction of crude glycerol which is therefore becoming a waste product instead of a valuable 'coproduct'. Glycerol can be used for the production of valuable chemicals, e.g. biofuels, to reduce glycerol waste disposal. In this study, a novel bacterial strain is described which converts glycerol mainly to ethanol and hydrogen with very little amounts of acetate, formate and 1,2-propanediol as coproducts. The bacterium offers certain advantages over previously studied glycerol-fermenting microorganisms...
January 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/27992794/a-comparison-between-corn-and-grain-sorghum-fermentation-rates-distillers-dried-grains-with-solubles-composition-and-lipid-profiles
#19
COMPARATIVE STUDY
David J Johnston, Robert A Moreau
The aim of this study was to determine if the compositional difference between grain sorghum and corn impact ethanol yields and coproduct value when grain sorghum is incorporated into existing corn ethanol facilities. Fermentation properties of corn and grain sorghum were compared utilizing two fermentation systems (conventional thermal starch liquefaction and native starch hydrolysis). Fermentation results indicated that protease addition influenced the fermentation rate and yield for grain sorghum, improving yields by 1-2% over non-protease treated fermentations...
February 2017: Bioresource Technology
https://www.readbyqxmd.com/read/27940633/supporting-underserved-patients-with-their-medicines-a-study-protocol-for-a-patient-professional-coproduced-education-intervention-for-community-pharmacy-staff-to-improve-the-provision-and-delivery-of-medicine-use-reviews-murs
#20
Asam Latif, Kristian Pollock, Claire Anderson, Justin Waring, Josie Solomon, Li-Chia Chen, Emma Anderson, Sulma Gulzar, Nasa Abbasi, Heather Wharrad
INTRODUCTION: Community pharmacy increasingly features in global strategies to modernise the delivery of primary healthcare. Medicine Use Reviews (MURs) form part of the English Government's medicines management strategy to improve adherence and reduce medicine waste. MURs provide space for patient-pharmacist dialogue to discuss the well-known problems patients experience with medicine taking. However, 'underserved' communities (eg, black and minority ethnic communities, people with mental illness), who may benefit the most, may not receive this support...
December 9, 2016: BMJ Open
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