keyword
https://read.qxmd.com/read/38455816/a-case-of-gemella-morbillorum-causing-multi-valvular-endocarditis
#21
Gabriel Panama, Adolfo Martinez, Majid Yavari, Andrew Geunwon Kim, George Abela
This is the case of a 31-year-old man with no significant past medical history who presented to the emergency department experiencing persistent fevers, chills, and malaise for the past 2-3 weeks. During this period, he had multiple urgent care visits for possible left-sided otitis media which was treated with short a course of Augmentin. While on antibiotics his symptoms would improve, but they would reappear once he had finished treatment. The patient also had significant dental carries with a chronic right molar infection...
February 2024: Curēus
https://read.qxmd.com/read/38453221/descending-necrotising-mediastinitis-a-rare-entity-in-children
#22
JOURNAL ARTICLE
Davide Lourenço Marques, Catarina Rato, António Miguéis, Jorge Miguéis
We present a case of descending necrotising mediastinitis (DNM) originating from a retropharyngeal abscess in a healthy early childhood patient. The patient had a history of fever, odynophagia and refusal to eat, followed by rapid deterioration of the clinical state. Cervicothoracic CT was performed, which revealed a right parapharyngeal abscess, extending to the mediastinum and occupying the retropharyngeal/visceral space, with gaseous content throughout this collection, associated with bilateral pleural effusion, aspects compatible with DNM...
March 7, 2024: BMJ Case Reports
https://read.qxmd.com/read/38449955/labial-necrotizing-fasciitis-caused-by-pelvic-eggerthia-catenaformis-infection
#23
Felix Yang, Mira Malavia, Ashna Chali, Jared Keeler
A patient with comorbid diabetes mellitus, obesity, and hypertension acutely presented to the ED due to labial cellulitis with rapidly progressing symptoms of systemic inflammation. Clinical examination revealed fever and groin pain that was tender to palpation. Initial contrast-enhanced CT scans showed labial cellulitis extending to the inguinal canal, with later CT imaging findings of subcutaneous air indicative of necrotizing fasciitis (NF). Antimicrobial therapy was initiated empirically and later tailored to culture antibiogram...
February 2024: Curēus
https://read.qxmd.com/read/38436172/prognostic-value-of-pleth-variability-index-in-patients-followed-up-in-the-intensive-care-unit
#24
JOURNAL ARTICLE
T Albayrak, B Yuksel
OBJECTIVE: The Pleth Variability Index (PVI) can guide the approach to hypovolemia, which is sometimes the cause and sometimes the result of major diseases; further studies are needed on this index. Therefore, in the present study, we aimed to evaluate the prognostic value of PVI and its relationship with 28-day mortality. PATIENTS AND METHODS: A total of 158 patients were included. Patients were divided into two groups according to 28-day mortality. Patients who died within 28 days were assigned to Group M (Mortal), while those who survived were included in Group S (Survive)...
February 2024: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/38433274/the-clinical-features-treatment-and-prognosis-of-neutropenic-fever-and-coronavirus-disease-2019-results-of-the-multicentre-teos-study
#25
MULTICENTER STUDY
Dilşah Başkol Elik, Şafak Kaya, Sevil Alkan, Tuna Demirdal, Alper Sener, Selçuk Kaya, Özlem Güzel Tunçcan, Bircan Kayaaslan, Rahmet Güner, Fatma Eser, Hasip Kahraman, Serhat Birengel, Elif Mukime Sarıcaoğlu, Esma Eroğlu, Fatma Çölkesen, Erman Öztürk, Hande Berk Cam, Çiğdem Mermutluoğlu, Şafak Özer Balin, Gülden Sincan, Nilgün Altın, Uluhan Sili, Bedia Mutay Suntur, Tuğba Arslan Gülen, Burak Deveci, Rabin Saba, Şaban İncecik, Gülden Eser Karlıdağ, Elif Hakko, Damla Akdağ, Hüseyin Aytaç Erdem, Hilal Sipahi, Candan Çicek, Mehmet Sezai Taşbakan, Meltem Taşbakan, Hüsnü Pullukçu, Tansu Yamazhan, Bilgin Arda, Sercan Ulusoy, Oguz Resat Sipahi
This multicentre (22 centres in Turkey) retrospective cohort study aimed to assess the clinical outcomes of patients with neutropenic fever and SARS-CoV-2 positivity. Study period was 15 March 2020-15 August 2021. A total of 170 cases (58 female, aged 59 ± 15.5 years) that fulfilled the inclusion criteria were included in the study. One-month mortality rate (OMM) was 44.8%. The logistic regression analysis showed the following significant variables for the mentioned dependent variables: (i) achieving PCR negativity: receiving a maximum of 5 days of favipiravir (p = 0...
March 3, 2024: Scientific Reports
https://read.qxmd.com/read/38433197/the-impact-of-gestational-weeks-of-coronavirus-disease-2019-covid-19-infection-on-perinatal-outcomes
#26
JOURNAL ARTICLE
Jiao Yi, Lei Chen, Xianglian Meng, Yi Chen
BACKGROUND: To evaluate the relationship between coronavirus disease 2019 (COVID-19) infection at different time points during pregnancy and perinatal outcomes. METHODS: This retrospective study included 611 women who hospitalized for delivery between December 7 and April 30, 2023. Based on the different pregnancy weeks infected with COVID-19, the participants were divided into four groups: Group 1 (14-27+6  weeks gestation), Group 2 (28-36+6  weeks gestation), Group 3 (37-39+6  weeks gestation), and Group 4 (≥ 40 weeks gestation)...
March 4, 2024: Reproductive Health
https://read.qxmd.com/read/38431948/clinical-manifestations-laboratory-tests-abdominal-ultrasonic-findings-and-in-hospital-prognosis-of-covid-19-in-185-pediatric-cases-in-a-tertiary-center
#27
JOURNAL ARTICLE
Maryam Jafari, Yasaman Mahalati, Elham Zarei, Mohammad Mahdi Kazemi, Arsalan Irompour, Amirhoessein Sadri, Hamed AzadiYekta
BACKGROUND: Despite the COVID-19 pandemic, there is little information about the different clinical aspects of COVID-19 in children. In this study, we assessed the clinical manifestations, outcome, ultrasound, and laboratory findings of pediatric COVID-19. METHODS: This retrospective study was conducted on 185 children with definitive diagnosis of COVID-19 between 2021 and 2022. The patients' information was retrieved from hospital records. RESULTS: The average age of the patients was 5...
December 1, 2023: Archives of Iranian Medicine
https://read.qxmd.com/read/38427413/the-effect-of-body-temperature-changes-on-the-course-of-treatment-in-patients-with-pneumonia-and-sepsis-results-of-an-observational-study
#28
JOURNAL ARTICLE
Domen Guzelj, Anže Grubelnik, Nina Greif, Petra Povalej Bržan, Jure Fluher, Žiga Kalamar, Andrej Markota
BACKGROUND: Traditionally, patients who are critically ill with infection and fever have been treated with antipyretics or even physically cooled. Presumed benefits of the reduction of body temperature are mostly based on decreased metabolic demands. However, it has been shown that decreasing body temperature in patients who are critically ill is not associated with improvement in treatment outcomes. Additionally, there is some data to support the use of temperature modulation (therapeutic hyperthermia) as an adjuvant treatment strategy in patients with infection...
March 1, 2024: Interactive Journal of Medical Research
https://read.qxmd.com/read/38420296/unmasking-the-enigma-of-weil-s-disease-a-case-report
#29
Yusuf Yalcin, Ibrahim Kamel, Harinder Singh
We present the case of a 37-year-old male with Weil's disease, a severe form of leptospirosis, who presented without typical ecological risk factors. Initially manifesting as weakness, muscle aches, and fever, the patient rapidly deteriorated, necessitating ICU admission due to septic shock and respiratory failure. Despite initial diagnostic challenges, including normal initial imaging and inconclusive laboratory findings, a presumptive diagnosis of leptospirosis was made using Modified Faine's criteria. Empirical antibiotic treatment with doxycycline led to significant clinical improvement, highlighting the importance of early recognition and treatment in severe cases of leptospirosis...
February 2024: Curēus
https://read.qxmd.com/read/38417865/stss-by-streptococcus-pyogenes-emm22-genotype-accompanied-by-csrs-mutation-a-case-report
#30
JOURNAL ARTICLE
Kaoru Ogawa, Jiro Kamiyama, Tadayoshi Ikebe, Shigemasa Taguchi, Kazuya Kiyota
The patient was a 22-year-old woman with no comorbidities who was transferred to our hospital due to cardiac arrest. Treatment enabled return to spontaneous circulation in the patient before arriving at the hospital. At the hospital, the patient's vital signs were unstable. Vasopressors and hyperhydration therapy were administered. Computed Tomography (CT) showed no remarkable change that caused the cardiac arrest. Antibiotics were prescribed after a blood culture exam. The patient was admitted to the ICU. In the ICU, the high-capacity vasopressors, hyperhydration therapy and transfusion of fresh frozen plasma were continued...
February 29, 2024: Japanese Journal of Infectious Diseases
https://read.qxmd.com/read/38416105/analysis-of-adverse-events-in-the-postanesthesia-unit-at-a-tertiary-pediatric-hospital
#31
JOURNAL ARTICLE
Aihua Liu, Yun Shi
PURPOSE: The postanesthesia care unit (PACU) is an indispensable part of modern medicine which provides critical care to patients to ensure safe and smooth emergence from anesthesia. The adverse events in the PACU have been widely investigated in adults. However, little is known about the adverse events in pediatric populations. This study was designed to investigate adverse events, including the incidence, disease spectrum, and possible risk factors, in pediatric patients in the PACU at a tertiary pediatric hospital...
February 26, 2024: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://read.qxmd.com/read/38408061/clinical-predictors-of-severe-forms-of-influenza-a-h1n1-pdm09-in-adults-and-children-during-the-2009-epidemic-in-brazil
#32
JOURNAL ARTICLE
Jose Ueleres Braga
The World Health Organization (WHO) raised the global alert level for the A(H1N1) influenza pandemic in June 2009. However, since the beginning of the epidemic, the fight against the epidemic lacked foundations for managing cases to reduce the disease lethality. It was urgent to carry out studies that would indicate a model for predicting severe forms of influenza. This study aimed to identify risk factors for severe forms during the 2009 influenza epidemic and develop a prediction model based on clinical epidemiological data...
2024: PloS One
https://read.qxmd.com/read/38406150/exploring-the-relationship-of-comorbidities-smoking-status-hrct-findings-with-covid-19-disease-severity-and-outcomes
#33
JOURNAL ARTICLE
Sohail Khan Raja, Rubina Rafique Shiekh, Mohammad Ali Arshad Abbasi, Samia Tariq, Humayun Saleem, Maham Tariq, Amna Akbar, Sarosh Khan Jadoon, Sabahat Tasneem, Mohammad Saleem Khan
INTRODUCTION: Coronavirus disease 2019 (COVID-19) is a serious illness that can affect multiple organs including the lungs. The COVID-mortality risk is attributed to the quick transmission of the virus, the severity of disease, and preclinical risk factors, such as the presence of comorbidities. High-resolution computed tomography (HRCT) can predict disease severity in COVID-19 patients. METHODOLOGY: This was a retrospective cohort study in which data were obtained from COVID centers at tertiary care hospitals in Azad Jammu and Kashmir...
January 2024: Curēus
https://read.qxmd.com/read/38406070/toxic-shock-syndrome-eighteen-years-of-experience-in-a-pediatric-intensive-care-unit
#34
JOURNAL ARTICLE
Inês Cascais, Ana Losa, Cláudia Correia, Diana H Pinto, Daniel Meireles, Alzira Sarmento
Introduction Toxic shock syndrome (TSS) is a life-threatening disease usually caused by a Staphylococcus aureus or group Aβ-hemolytic Streptococcus infection. Methods In this retrospective study, we included patients with TSS admitted to a tertiary hospital's pediatric intensive care unit (PICU) over the last 18 years. We compared the staphylococcal TSS (Staph-TSS) and streptococcal TSS (Strep-TSS) groups. Results We included 17 patients (64.7% male), with a median age of 6.1 years (3.0 years for streptococcal TSS versus 13...
January 2024: Curēus
https://read.qxmd.com/read/38402650/early-changes-in-skin-surface-temperature-predict-body-temperature-increases-in-patients-with-fever-a-pilot-study
#35
JOURNAL ARTICLE
Yi-Ting Chung, Chun-Yin Yeh, Chang-Chun Chen, Chao-Han Lai, Yi-Hsuan Lin, Chung-Ying Lin, Yu-Chen Shu, Nai-Ying Ko
OBJECTIVE: To investigate the correlation between body temperature and skin surface temperature in intensive care unit patients and to identify specific indicators of skin surface temperature for early fever detection. RESEARCH METHODOLOGY/DESIGN: This pilot study was a prospective, observational investigation conducted at National Cheng Kung University Hospital in Tainan, Taiwan. A total of 54 patients admitted to the Surgical Intensive Care Unit of a tertiary hospital between April and August 2020 were included...
February 24, 2024: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://read.qxmd.com/read/38389624/caudal-neuraxial-blocks-for-pain-relief-from-pelvic-neuropathy-caused-by-extensive-diffuse-large-b-cell-lymphoma
#36
Amanda Myles, Ammar Toubasi, Elizabeth Soladoye, Narayana Gowda, Joan Morny
Central neuraxial blocks can be a vital therapeutic tool for neuropathic pain, but they are infrequently implemented for pain management in cancer patients. Upon a literature review, further data on the role or efficacy of central nerve blocks for neuropathic cancer pain would be beneficial. Additionally, evidence-based guidelines and practices are lacking regarding additional interventions for neuropathic pain relief, a common manifestation of cancer burden. Here, we report the case of a 29-year-old male patient who presented in the ED with intractable neuropathic pain from extensive diffuse large B-cell lymphoma...
January 2024: Curēus
https://read.qxmd.com/read/38388223/the-role-of-preoperative-transfusion-in-sickle-cell-disease-a-systematic-review-and-meta-analysis
#37
REVIEW
Yasamin Abdu, Alaa Rahhal, Khalid Ahmed, Nada Adli, Mariam Abdou, Elrazi Awadelkarim Hamid Ali, Salam Al-Kindi, Mona Al Rasheed, Jaffer Altooq, Iheb Bougmiza, Mohamed A Yassin
This systematic review and meta-analysis aimed to provide guidance on preoperative blood transfusion strategies for patients with sickle cell disease (SCD). We included all randomized controlled and observational studies exploring the clinical outcomes of preoperative blood transfusion among patients with SCD compared to the conservative transfusion strategy until 14/09/2022. Sixteen studies involving 3486 participants were analysed. The findings revealed a significantly higher bleeding rate in patients who received preoperative transfusion than those who followed a conservative strategy (RR = 4...
February 18, 2024: Blood Reviews
https://read.qxmd.com/read/38384617/plasma-exchange-in-pediatric-neurology-patients-a-single-center-experience
#38
JOURNAL ARTICLE
Maram A Aljezani, Faris Althubaiti, Latifah Alhamed, Abdulrahman Alharthi, Abdulaziz Alamoodi, Yousof Bakheet, Maha Badawi, Salwa Hindawi
BACKGROUND: Therapeutic plasma exchange (TPE) is a procedure involving the filtration of a patient's plasma to eliminate pathogenic components or address deficiencies. This technique finds varied indications in the pediatric age group, particularly in neuroinflammatory diseases. OBJECTIVES: The objective of this study is to delve into our local experience with TPE, focusing on indications, outcomes, and complications among children with neurological diseases at King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia...
January 2024: Curēus
https://read.qxmd.com/read/38382145/retroperitoneal-necrotizing-fasciitis-mimicking-perforated-appendicitis-a-case-report
#39
Negassa Getachew Tarekegn, Tadesse Girma Moges, Feyera Abetu Guluju
INTRODUCTION: Necrotizing fasciitis (NF) is a rare and rapidly progressing soft tissue infection. The commonly involved body parts are the extremities and trunk. Necrotizing fasciitis (NF) involving the retroperitoneum is very uncommon but associated with higher morbidity and mortality. There are only a few patients survived according to the report. PRESENTATION OF CASE: This is a 19-year-old male patient presented with abdominal pain, high-grade fever, vomiting and abdominal distension for 3 days...
February 20, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38371066/characteristics-and-outcomes-of-children-with-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-admitted-to-a-quaternary-hospital-a-single-center-experience
#40
JOURNAL ARTICLE
Saleh S Alshehri, Bushra I Minhaji, Mohsina R Pasha, Dina Fouda, Jency Joseph, Nehad Ahmed
Objectives In the setting of the recent global pandemic, children infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus causing the coronavirus disease 2019 (COVID-19) presented to our hospital with a variety of symptoms ranging from mild to severe disease including multiorgan dysfunction. Our objective was to study the clinical profile, risk factors, complications, and outcomes in pediatric patients admitted to our center with SARS-CoV-2 infection. Methods This retrospective observational study was conducted at a large quaternary center in Riyadh between May 2020 and September 2021...
January 2024: Curēus
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