keyword
MENU ▼
Read by QxMD icon Read
search

Chris Powers

keyword
https://www.readbyqxmd.com/read/29239783/early-adulthood-determinants-of-mid-life-leisure-time-physical-inactivity-stability-and-change-findings-from-a-prospective-birth-cohort
#1
Snehal M Pinto Pereira, Chris Power
OBJECTIVES: Physical inactivity is highly prevalent. Knowledge is needed of influences on inactive lifestyles. We aimed to establish whether early adult factors predict subsequent inactivity patterns in mid-adulthood. DESIGN: Leisure-time inactivity (activity frequency<1/week) was assessed at 33y and 50y in the 1958 British Birth cohort (N=12,271). METHODS: We assessed associations of early adult (23-33y) physical status, mental function, social, family and neighbourhood circumstances with four 33-50y patterns (never inactive, persistently inactive, deteriorating or improving) using multinomial logistic regression with and without adjustment for childhood factors (e...
November 22, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29236038/adverse-effects-of-amoxicillin-for-acute-lower-respiratory-tract-infection-in-primary-care-secondary-and-subgroup-analysis-of-a-randomised-clinical-trial
#2
Meera Tandan, Akke Vellinga, Robin Bruyndonckx, Paul Little, Theo Verheij, Chris C Butler, Herman Goossens, Samuel Coenen
A European placebo-controlled trial of antibiotic treatment for lower respiratory tract infection (LRTI) conducted in 16 primary care practices networks recruited participants between November 2007 and April 2010, and found adverse events (AEs) occurred more often in patients prescribed amoxicillin compared to placebo. This secondary analysis explores the causal relationship and estimates specific AEs (diarrhoea, nausea, rash) due to amoxicillin treatment for LRTI, and if any subgroup is at increased risk of any or a specific AE...
December 13, 2017: Antibiotics
https://www.readbyqxmd.com/read/29226437/on-effective-graphic-communication-of-health-inequality-considerations-for-health-policy-researchers
#3
Yukiko Asada, Hannah Abel, Chris Skedgel, Grace Warner
Policy Points: Effective graphs can be a powerful tool in communicating health inequality. The choice of graphs is often based on preferences and familiarity rather than science. According to the literature on graph perception, effective graphs allow human brains to decode visual cues easily. Dot charts are easier to decode than bar charts, and thus they are more effective. Dot charts are a flexible and versatile way to display information about health inequality. Consistent with the health risk communication literature, the captions accompanying health inequality graphs should provide a numerical, explicitly calculated description of health inequality, expressed in absolute and relative terms, from carefully thought-out perspectives...
December 2017: Milbank Quarterly
https://www.readbyqxmd.com/read/29214697/incorporation-of-2-6-connected-azulene-units-into-the-backbone-of-conjugated-polymers-towards-high-performance-organic-optoelectronic-materials
#4
Xike Gao, Hanshen Xin, Congwu Ge, Xuechen Jiao, Xiaodi Yang, Kira Rundel, Chris McNeill
Azulene is considered to be a promising candidate for constructing optoelectronic materials. We present herein an effective strategy to obtain high performance conjugated polymers by incorporating 2,6-connected azulene units into the polymeric backbone, and two conjugated copolymers P(TBAzDI-TPD) and P(TBAzDI-TFB) are designed and synthesized based on this strategy. They are the first two examples for 2,6-connected azulene-based conjugated polymers and exhibit unipolar n-type transistor performance with an electron mobility of up to 0...
December 7, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29206564/advance-care-planning-in-an-accountable-care-organization-is-associated-with-increased-advanced-directive-documentation-and-decreased-costs
#5
William F Bond, Minchul Kim, Chris M Franciskovich, Jason E Weinberg, Jessica D Svendsen, Linda S Fehr, Amy Funk, Robert Sawicki, Carl V Asche
BACKGROUND: Advance care planning (ACP) documents patient wishes and increases awareness of palliative care options. OBJECTIVE: To study the association of outpatient ACP with advanced directive documentation, utilization, and costs of care. DESIGN: This was a case-control study of cases with ACP who died matched 1:1 with controls. We used 12 months of data pre-ACP/prematch and predeath. We compared rates of documentation with logit model regression and conducted a difference-in-difference analysis using generalized linear models for utilization and costs...
December 5, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29201547/decremental-responses-in-patients-with-motor-neuron-disease
#6
Mohammed H Alanazy, Janka Hegedus, Chris White, Lawrence Korngut
Objective: Involvement of the neuromuscular junction (NMJ) in amyotrophic lateral sclerosis (ALS) has been reported and is increasingly recognized as an important pathophysiological aspect. The relationship between decrement and clinical measures for possible application as a biomarker has not been comprehensively explored. Methods: We performed routine repetitive nerve stimulation (RNS) of three nerves on patients with ALS. We captured measures of muscle strength, grip strength, fatigability, and calculated slow vital capacity (SVC) rates of change assessing for associations...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29195810/natural-parasite-exposure-induces-protective-human-anti-malarial-antibodies
#7
Gianna Triller, Stephen W Scally, Giulia Costa, Maria Pissarev, Cornelia Kreschel, Alexandre Bosch, Eric Marois, Brandon K Sack, Rajagopal Murugan, Ahmed M Salman, Chris J Janse, Shahid M Khan, Stefan H I Kappe, Ayola A Adegnika, Benjamin Mordmüller, Elena A Levashina, Jean-Philippe Julien, Hedda Wardemann
Antibodies against the NANP repeat of circumsporozoite protein (CSP), the major surface antigen of Plasmodium falciparum (Pf) sporozoites, can protect from malaria in animal models but are difficult to induce in humans. Here we cloned and characterized rare affinity-matured human NANP-reactive memory B cell antibodies elicited by natural Pf exposure that potently inhibited parasite transmission and development in vivo. We unveiled the molecular details of antibody binding to two distinct protective epitopes within the NANP repeat...
November 28, 2017: Immunity
https://www.readbyqxmd.com/read/29185706/scalable-production-of-graphene-based-wearable-e-textiles
#8
Nazmul Karim, Shaila Afroj, Sirui Tan, Pei He, Anura Fernando, Chris Carr, Kostya S Novoselov
Graphene-based wearable e-textiles are considered to be promising due to their advantages over traditional metal-based technology. However the manufacturing process is complex and currently not suitable for industrial scale application. Here we report a simple, scalable and cost-effective method of producing graphene-based wearable e-textiles through the chemical reduction GO to make stable rGO dispersions which can then be applied to the textile fabric using a simple pad-dry technique. This application method allows the potential manufacture of conductive graphene e-textiles at commercial production rates of ~150 m/min...
November 29, 2017: ACS Nano
https://www.readbyqxmd.com/read/29172375/governing-collaborative-healthcare-improvement-lessons-from-an-atlantic-canadian-case
#9
Meghan Rossiter, Jennifer Verma, Jean-Louis Denis, Stephen Samis, Richard Wedge, Chris Power
The Atlantic Healthcare Collaboration for Innovation and Improvement in Chronic Disease (AHC) Quality Improvement Collaborative (QIC) in Eastern Canada provided an approach to spur system-level reform across multiple health systems for patients and families living with chronic disease. Developed and led by senior executives with a unique governance approach and involving clinical front-line teams, the AHC serves as a practical example of leadership creating and driving momentum for achieving success in collaborative health system improvements...
May 16, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/29169329/micro-costing-analysis-of-guideline-based-treatment-by-direct-acting-agents-the-real-life-case-of-hepatitis-c-management-in-brazil
#10
Hugo Perazzo, Marcelino Jose Jorge, Julio Castro Silva, Alexandre Monken Avellar, Patrícia Santos Silva, Carmen Romero, Valdilea Gonçalves Veloso, Ruben Mujica-Mota, Rob Anderson, Chris Hyde, Rodolfo Castro
BACKGROUND: Eradication of hepatitis C virus (HCV) using direct-acting agents (DAA) has been associated with a financial burden to health authorities worldwide. We aimed to evaluate the guideline-based treatment costs by DAAs from the perspective of the Brazilian Ministry of Health (BMoH). METHODS: The activity based costing method was used to estimate the cost for monitoring/treatment of genotype-1 (GT1) HCV patients by the following strategies: peg-interferon (PEG-IFN)/ribavirin (RBV) for 48 weeks, PEG-IFN/RBV plus boceprevir (BOC) or telaprevir (TEL) for 48 weeks, and sofosbuvir (SOF) plus daclastavir (DCV) or simeprevir (SIM) for 12 weeks...
November 23, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/29169029/learning-normalized-inputs-for-iterative-estimation-in-medical-image-segmentation
#11
Michal Drozdzal, Gabriel Chartrand, Eugene Vorontsov, Mahsa Shakeri, Lisa Di Jorio, An Tang, Adriana Romero, Yoshua Bengio, Chris Pal, Samuel Kadoury
In this paper, we introduce a simple, yet powerful pipeline for medical image segmentation that combines Fully Convolutional Networks (FCNs) with Fully Convolutional Residual Networks (FC-ResNets). We propose and examine a design that takes particular advantage of recent advances in the understanding of both Convolutional Neural Networks as well as ResNets. Our approach focuses upon the importance of a trainable pre-processing when using FC-ResNets and we show that a low-capacity FCN model can serve as a pre-processor to normalize medical input data...
November 14, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/29164265/the-power-and-pitfalls-of-big-data-research-in-obstetrics-and-gynecology-a-consumer-s-guide
#12
Amie Goodin, Chris Delcher, Chelsea Valenzuela, Xi Wang, Yanmin Zhu, Dikea Roussos-Ross, Joshua D Brown
Importance: Research in obstetrics and gynecology (OB/GYN) increasingly relies on "big data" and observational study designs. There is a gap in practitioner-relevant guides to interpret and critique such research. Objective: This guide is an introduction to interpreting research using observational data and provides explanations and context for related terminology. In addition, it serves as a guide for critiquing OB/GYN studies that use observational data by outlining how to assess common pitfalls of experimental and observational study designs...
November 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/29163640/a-review-of-pathway-based-analysis-tools-that-visualize-genetic-variants
#13
REVIEW
Elisa Cirillo, Laurence D Parnell, Chris T Evelo
Pathway analysis is a powerful method for data analysis in genomics, most often applied to gene expression analysis. It is also promising for single-nucleotide polymorphism (SNP) data analysis, such as genome-wide association study data, because it allows the interpretation of variants with respect to the biological processes in which the affected genes and proteins are involved. Such analyses support an interactive evaluation of the possible effects of variations on function, regulation or interaction of gene products...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/29163232/considerations-on-the-assessment-and-use-of-cycling-performance-metrics-and-their-integration-in-the-athlete-s-biological-passport
#14
Paolo Menaspà, Chris R Abbiss
Over the past few decades the possibility to capture real-time data from road cyclists has drastically improved. Given the increasing pressure for improved transparency and openness, there has been an increase in publication of cyclists' physiological and performance data. Recently, it has been suggested that the use of such performance biometrics may be used to strengthen the sensitivity and applicability of the Athlete Biological Passport (ABP) and aid in the fight against doping. This is an interesting concept which has merit, although there are several important factors that need to be considered...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29163120/the-myosuit-bi-articular-anti-gravity-exosuit-that-reduces-hip-extensor-activity-in-sitting-transfers
#15
Kai Schmidt, Jaime E Duarte, Martin Grimmer, Alejandro Sancho-Puchades, Haiqi Wei, Chris S Easthope, Robert Riener
Muscle weakness-which can result from neurological injuries, genetic disorders, or typical aging-can affect a person's mobility and quality of life. For many people with muscle weakness, assistive devices provide the means to regain mobility and independence. These devices range from well-established technology, such as wheelchairs, to newer technologies, such as exoskeletons and exosuits. For assistive devices to be used in everyday life, they must provide assistance across activities of daily living (ADLs) in an unobtrusive manner...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/29146666/students-in-fully-online-programs-report-more-positive-attitudes-toward-science-than-students-in-traditional-in-person-programs
#16
Viranga Perera, Chris Mead, Sanlyn Buxner, David Lopatto, Lev Horodyskyj, Steven Semken, Ariel D Anbar
Following the growth of online, higher-education courses, academic institutions are now offering fully online degree programs. Yet it is not clear how students who enroll in fully online degree programs are similar to those students who enroll in in-person ("traditional") degree programs. Because previous work has shown students' attitudes toward science can affect their performance in a course, it is valuable to ask how attitudes toward science differ between these two populations. We studied students who completed a fully online astrobiology course...
2017: CBE Life Sciences Education
https://www.readbyqxmd.com/read/29134577/perspective-taking-and-theory-of-mind-in-hide-and-seek
#17
Chris N H Street, Walter F Bischof, Alan Kingstone
Does theory of mind play a significant role in where people choose to hide an item or where they search for an item that has been hidden? Adapting Anderson's "Hide-Find Paradigm" Anderson et al. (Action, Perception and Performance, 76, 907-913, 2014) participants viewed homogenous or popout visual arrays on a touchscreen table. Their task was to indicate where in the array they would hide an item, or to search for an item that had been hidden, by either a friend or a foe. Critically, participants believed that their sitting location at the touchtable was the same as-or opposite to-their partner's location...
November 13, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/29125613/control-of-electro-chemical-processes-using-energy-harvesting-materials-and-devices
#18
REVIEW
Yan Zhang, Mengying Xie, Vana Adamaki, Hamideh Khanbareh, Chris R Bowen
Energy harvesting is a topic of intense interest that aims to convert ambient forms of energy such as mechanical motion, light and heat, which are otherwise wasted, into useful energy. In many cases the energy harvester or nanogenerator converts motion, heat or light into electrical energy, which is subsequently rectified and stored within capacitors for applications such as wireless and self-powered sensors or low-power electronics. This review covers the new and emerging area that aims to directly couple energy harvesting materials and devices with electro-chemical systems...
November 10, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/29123116/india-is-overtaking-china-as-the-world-s-largest-emitter-of-anthropogenic-sulfur-dioxide
#19
Can Li, Chris McLinden, Vitali Fioletov, Nickolay Krotkov, Simon Carn, Joanna Joiner, David Streets, Hao He, Xinrong Ren, Zhanqing Li, Russell R Dickerson
Severe haze is a major public health concern in China and India. Both countries rely heavily on coal for energy, and sulfur dioxide (SO2) emitted from coal-fired power plants and industry is a major pollutant contributing to their air quality problems. Timely, accurate information on SO2 sources is a required input to air quality models for pollution prediction and mitigation. However, such information has been difficult to obtain for these two countries, as fast-paced changes in economy and environmental regulations have often led to unforeseen emission changes...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29117557/the-role-of-eif6-in-skeletal-muscle-homeostasis-revealed-by-endurance-training-co-expression-networks
#20
Kim Clarke, Sara Ricciardi, Tim Pearson, Izwan Bharudin, Peter K Davidsen, Michela Bonomo, Daniela Brina, Alessandra Scagliola, Deborah M Simpson, Robert J Beynon, Farhat Khanim, John Ankers, Mark A Sarzynski, Sujoy Ghosh, Addolorata Pisconti, Jan Rozman, Martin Hrabe de Angelis, Chris Bunce, Claire Stewart, Stuart Egginton, Mark Caddick, Malcolm Jackson, Claude Bouchard, Stefano Biffo, Francesco Falciani
Regular endurance training improves muscle oxidative capacity and reduces the risk of age-related disorders. Understanding the molecular networks underlying this phenomenon is crucial. Here, by exploiting the power of computational modeling, we show that endurance training induces profound changes in gene regulatory networks linking signaling and selective control of translation to energy metabolism and tissue remodeling. We discovered that knockdown of the mTOR-independent factor Eif6, which we predicted to be a key regulator of this process, affects mitochondrial respiration efficiency, ROS production, and exercise performance...
November 7, 2017: Cell Reports
keyword
keyword
107367
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"