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https://www.readbyqxmd.com/read/29679898/heart-rate-variability-alterations-in-late-life-depression-a-meta-analysis
#1
REVIEW
Lydia Brown, Chandan Karmakar, Richard Gray, Ripu Jindal, Terrence Lim, Christina Bryant
OBJECTIVE: There is strong evidence for a bi-directional relationship between heart-health and depression in later life, but the physiological mechanisms underlying this relationship remain unclear. Heart rate variability is one promising factor that might help explain this relationship. We present results of a meta-analysis that considers heart rate variability alterations in older adults with depression. METHODS: Literature search of Embase, PsychInfo and Medline revealed five clinical studies and six observational studies that examined the relationship between heart rate variability and depression in adults with a mean age over 60...
April 10, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29679895/ingredientes-farmac%C3%A3-uticos-activos-potencialmente-inapropiados-en-adultos-mayores-lista-ifaspiam-panel-de-consenso-argentino
#2
Marta M Marzi, Miryam S Pires, Nora B Quaglia
OBJECTIVES: To perform a list agreed by Argentinean experts and adapted to the local context containing potentially inappropriate (PI) medications in old people (OP) usingthe Delphi consensus technique optimized for this subject. METHODS: A preliminary list of potentially inappropriate medications (PIM) was drawn up based on foreign PIM lists and a selective search in the scientific literature. The iterative Delphi process was used to submit the active pharmaceutical ingredients (APIs) of the preliminary PIM list to the panel of Argentinean experts...
April 18, 2018: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29679596/observational-studies-of-inhaled-corticosteroid-effectiveness-in-copd-lessons-learned
#3
Samy Suissa, Pierre Ernst
BACKGROUND: Randomized controlled trials at times investigate findings suggested by observational studies. For example, the TORCH trial, which did not show a mortality reduction with inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD), was motivated by some observational studies that suggested considerable reductions in mortality with these drugs. Reasons for these discrepancies are unclear. METHODS: We searched the literature to identify all observational studies, including cohort and case-control studies, investigating the effectiveness of ICS on major outcomes in COPD patients, including death and hospitalization for COPD...
April 18, 2018: Chest
https://www.readbyqxmd.com/read/29679513/weight-suppression-as-a-predictor-variable-in-the-treatment-of-eating-disorders-a-systematic-review
#4
REVIEW
Paul E Jenkins, Jocelyn Lebow, Renee D Rienecke
INTRODUCTION: Weight suppression (WS - the difference between highest body weight and current body weight) has been proposed as a predictor of treatment outcome within eating disorders (EDs), although this hypothesis has not been consistently supported. AIM/QUESTION: Review the association between pre-treatment WS and outcome following psychological treatment for EDs. METHOD: A comprehensive electronic database search for published and unpublished literature from 1979 to 2017...
April 21, 2018: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/29679414/rates-and-features-of-methamphetamine-related-presentations-to-emergency-departments-an-integrative-literature-review
#5
REVIEW
Rikki Jones, Cindy Woods, Kim Usher
AIMS AND OBJECTIVES: To review the clinical impact methamphetamine has on emergency departments (ED) by assessing the available research on the rates and features of methamphetamine-related presentations. BACKGROUND: Globally, methamphetamine availability, distribution and use has rapidly increased. As a result, the number of methamphetamine-related presentations to EDs has also increased. In this context, it is timely to review the rate and features of methamphetamine-related presentations to understand the impact of methamphetamine on EDs and facilitate the allocation of services, staff and resources...
April 20, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29679255/needle-tissue-interactive-mechanism-and-steering-control-in-image-guided-robot-assisted-minimally-invasive-surgery-a-review
#6
Pan Li, Zhiyong Yang, Shan Jiang
Image-guided robot-assisted minimally invasive surgery is an important medicine procedure used for biopsy or local target therapy. In order to reach the target region not accessible using traditional techniques, long and thin flexible needles are inserted into the soft tissue which has large deformation and nonlinear characteristics. However, the detection results and therapeutic effect are directly influenced by the targeting accuracy of needle steering. For this reason, the needle-tissue interactive mechanism, path planning, and steering control are investigated in this review by searching literatures in the last 10 years, which results in a comprehensive overview of the existing techniques with the main accomplishments, limitations, and recommendations...
April 21, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29679215/diagnostic-role-of-serum-tryptase-in-anaphylactic-deaths-in-forensic-medicine-a-systematic-review-and-meta-analysis
#7
REVIEW
Kai-Jian Sun, Jie-Tao He, Hong-Yan Huang, Ye Xue, Xiao-Li Xie, Qi Wang
Postmortem diagnosis of sudden death due to anaphylaxis can be very difficult due to the non-specific pathological findings in forensic practice. Postmortem serum tryptase has been used as an indicator of possible ante-mortem anaphylaxis. Though many previous studies have been conducted to explore the diagnostic significance of serum tryptase for lethal anaphylaxis, inconsistent results were documented. In this study, we made a retrospective study and presented a systematic review and meta-analysis that aims to summarize the diagnostic significance of postmortem serum tryptase in the deceased with and without anaphylactic shock and to calculate a cutoff value for future reference in the identification of deaths due to anaphylactic shock...
April 21, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29679134/aphallia-a-review-to-standardize-management
#8
REVIEW
Tarryn Gabler, Robyn Charlton, Jerome Loveland, Ellen Mapunda
Congenital aphallia is a rare anomaly with little supporting literature and controversial management. The aim of this review is to assess the most recent literature with a focus on staged management of these cases. We performed a PubMed search of all English literature in the past 10 years using the term aphallia. Twenty-three articles were identified of which six were excluded. A further three papers meeting our criteria were found in the references to papers initially identified. We found that management can be staged in three phases: short, intermediate and long-term...
April 20, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29679129/-operative-treatment-of-degenerative-diseases-of-the-lumbar-spine
#9
REVIEW
M Czabanka, C Thomé, F Ringel, B Meyer, S-O Eicker, V Rohde, M Stoffel, P Vajkoczy
BACKGROUND: Degenerative diseases of the lumbar spine and associated lower back pain represent a major epidemiological and health-related economic challenge. A distinction is made between specific and unspecific lower back pain. In specific lower back pain lumbar disc herniation and spinal canal stenosis with or without associated segment instability are among the most frequent pathologies. Diverse conservative and operative strategies for treatment of these diseases are available. OBJECTIVES: The aim of this article is to present an overview of current data and an evidence-based assessment of the possible forms of treatment...
April 20, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29679126/-surgical-treatment-of-adult-spinal-deformities
#10
REVIEW
S M Krieg, P Vajkoczy, S-O Eicker, V Rohde, C Thome, M Stoffel, F Ringel, B Meyer
BACKGROUND: Adult spinal deformity (ASD) is mostly a progressive disease which usually leads to chronic pain. Due to increased prevalence in older people many patients suffer from comorbidities, which make conservative and surgical treatment even more complex. OBJECTIVE: This article provides an overview on the current conservative and surgical treatment options. MATERIAL AND METHODS: An extensive literature search was carried out via Medline plus an additional evaluation of the authors' personal experiences was performed...
April 20, 2018: Der Nervenarzt
https://www.readbyqxmd.com/read/29679109/parallel-versus-orthogonal-plate-osteosynthesis-of-adult-distal-humerus-fractures-a-meta-analysis-of-biomechanical-studies
#11
Chien-An Shih, Wei-Ren Su, Wei-Chin Lin, Tai-Wei Tai
PURPOSE: There are two widely used distal humerus fracture (DHF) fixation methods with either orthogonal or parallel double-plate osteosynthesis. However, biomechanical studies have shown inconsistent results on which technique is more effective. We performed a meta-analysis to compare these two fixation methods for adult DHF fixation. METHODS: We searched the literature for entries discussing the biomechanical testing of orthogonal and parallel fixation techniques for DHFs...
April 20, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29679099/radiation-induced-carotid-artery-lesions
#12
REVIEW
Verónica Fernández-Alvarez, Fernando López, Carlos Suárez, Primoz Strojan, Avraham Eisbruch, Carl E Silver, William M Mendenhall, Johannes A Langendijk, Alessandra Rinaldo, Anne W M Lee, Jonathan J Beitler, Robert Smee, Javier Alvarez, Alfio Ferlito
PURPOSE: To review the current aspects of knowledge related to the risk of cerebrovascular events in patients receiving head and neck radiotherapy. METHODS: A literature search was performed in PubMed. Papers meeting selection criteria were reviewed. RESULTS: We provide an update on the problem by identifying key studies that have contributed to our current understanding of the epidemiology, radiologic features, pathogenesis, and treatment of the disease...
April 20, 2018: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/29678991/measurement-properties-of-the-health-of-the-nation-outcome-scales-honos-family-of-measures-protocol-for-a-systematic-review
#13
Meredith G Harris, Claudia Sparti, Roman Scheurer, Tim Coombs, Jane Pirkis, Torleif Ruud, Steve Kisely, Ketil Hanssen-Bauer, Johan Siqveland, Philip M Burgess
INTRODUCTION: The Health of the Nation Outcome Scales (HoNOS) for adults, and equivalent measures for children and adolescents and older people, are widely used in clinical practice and research contexts to measure mental health and functional outcomes. Additional HoNOS measures have been developed for special populations and applications. Stakeholders require synthesised information about the measurement properties of these measures to assess whether they are fit for use with intended service settings and populations and to establish performance benchmarks...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678805/mobile-health-to-maintain-continuity-of-patient-centered-care-for-chronic-kidney-disease-content-analysis-of-apps
#14
Ying-Li Lee, Yan-Yan Cui, Ming-Hsiang Tu, Yu-Chi Chen, Polun Chang
BACKGROUND: Chronic kidney disease (CKD) is a global health problem with a high economic burden, which is particularly prevalent in Taiwan. Mobile health apps have been widely used to maintain continuity of patient care for various chronic diseases. To slow the progression of CKD, continuity of care is vital for patients' self-management and cooperation with health care professionals. However, the literature provides a limited understanding of the use of mobile health apps to maintain continuity of patient-centered care for CKD...
April 20, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29678669/using-big-data-in-oncology-to-prospectively-impact-clinical-patient-care-a-proof-of-concept-study
#15
Vérène Dougoud-Chauvin, Jae Jin Lee, Edgardo Santos, Vonetta L Williams, Nicolò M L Battisti, Kavita Ghia, Marina Sehovic, Cortlin Croft, Jongphil Kim, Lodovico Balducci, Julie A Kish, Martine Extermann
OBJECTIVE: Big Data is widely seen as a major opportunity for progress in the practice of personalized medicine, attracting the attention from medical societies and presidential teams alike as it offers a unique opportunity to enlarge the base of evidence, especially for older patients underrepresented in clinical trials. This study prospectively assessed the real-time availability of clinical cases in the Health & Research Informatics Total Cancer Care™ (TCC) database matching community patients with cancer, and the impact of such a consultation on treatment...
April 17, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29678668/the-effect-of-music-on-postoperative-recovery-in-older-patients-a-systematic-review
#16
Hanneke van der Wal-Huisman, Karolien S K Dons, Rineke Smilde, Erik Heineman, Barbara L van Leeuwen
OBJECTIVE: Surgery is an important part of the treatment modalities offered to older patients with cancer. Natural ageing processes lead to deterioration of organ function, making older patients more vulnerable and at risk for experiencing less-favourable outcomes and complications after surgery. Non-pharmaceutical interventions, such as music, may be preferable to medical interventions in older people, who are at risk for adverse effects and drug interactions due to altered physiology and drug metabolism...
April 17, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29678659/association-of-cyp3a4-1b-genotype-with-cyclosporin-a-pharmacokinetics-in-renal-transplant-recipients-a-meta-analysis
#17
Cai-E Wang, Ke-Peng Lu, Zhao Chang, Meng-Li Guo, Hai-Ling Qiao
OBJECTIVE: Cyclosporine (CsA) is a substrate of cytochrome P450 (CYP) 3A4 with a narrow therapeutic index and large individual difference. CYP3A4*1B is reported to be associated with CsA pharmacokinetics parameters, but the relevance is still in dispute. Therefore, a meta-analysis was employed to evaluate the influence of CYP3A4*1B on CsA pharmacokinetics at different post-transplantation times in adult renal transplant recipients. METHODS: Studies on evaluating the CYP3A4*1B genotype and CsA pharmacokinetics were retrieved through a systematical search of relevant database including PubMed, Emabase, Web of science, the Cochrane Library, Clinical Trials...
April 17, 2018: Gene
https://www.readbyqxmd.com/read/29678643/a-systematic-review-of-neuropsychological-studies-involving-young-binge-drinkers
#18
REVIEW
Carina Carbia, Eduardo López-Caneda, Montserrat Corral, Fernando Cadaveira
Binge drinking (BD) is a public health concern with serious implications for brain development. This review is the first in which neuropsychological studies of healthy young BDs are synthesized following PRISMA guidelines. We conducted a literature search in PsycINFO, Web of Science, and PubMed. Articles were screened using strict inclusion criteria. Two authors independently assessed the methodological quality. Of the 27 studies included, 14 (52%) were of intermediate quality, 7 (26%) of poor quality and 6 (22%) of high quality...
April 17, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29678631/platelet-to-lymphocyte-ratio-in-advanced-cancer-review-and-meta-analysis
#19
REVIEW
Bo Li, Pingting Zhou, Yujie Liu, Haifeng Wei, Xinghai Yang, Tianrui Chen, Jianru Xiao
BACKGROUND: Inflammation biomarkers have been introduced into clinical practice for risk-rating in treatment of patients with cancer. We aimed to confirm the prognostic role of platelet-to-lymphocyte ratio (PLR) as a powerful biomarker for patients with advanced cancer. METHOD: A systematic literature search was conducted through PubMed, Embase and Web of Science databases for studies on advanced tumors. Research articles that analyzed the PLR and hazard ratios (HR) in patients with overall survival (OS) or progression-free survival (PFS) data were involved...
April 17, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29678513/review-of-blood-based-colorectal-cancer-screening-how-far-are-circulating-cell-free-dna-methylation-markers-from-clinical-implementation
#20
REVIEW
Mai-Britt Worm Ørntoft
Colorectal cancer (CRC) is a leading cause of cancer related deaths worldwide, and late stages (III-IV) in particular have low 5-year survival rates. Stage shifting by CRC screening programs has proven effective by decreasing morbidity and mortality and in many countries national CRC screening programs have been implemented. Currently, European, Asian, and American authorities recommend screening for CRC using fecal occult blood testing, sigmoidoscopy, or colonoscopy. Because these approaches all have weaknesses (eg, poor compliance, high costs, test invasiveness), much effort has been put into the development of alternative screening approaches, many of which are blood-based...
March 2, 2018: Clinical Colorectal Cancer
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