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Xiao Xie, Hao Sun, Qing Zeng, Pengcheng Lu, Yijin Zhao, Tao Fan, Guozhi Huang
OBJECTIVE: To determine whether robot-assisted gait training (RAGT) is more effective in improving mobility, endurance, gait performance, and balance in patients with multiple sclerosis (MS) compared with conventional walking rehabilitation treatment (CWT). DATA SOURCES: Sources included the Cochrane Library, PubMed, Embase, and Science Direct databases. REVIEW METHOD: All possible articles were retrieved by two independent investigators and relevant articles were gathered...
2017: Frontiers in Neurology
Sofia Straudi, Fabio Manfredini, Nicola Lamberti, Paolo Zamboni, Francesco Bernardi, Giovanna Marchetti, Paolo Pinton, Massimo Bonora, Paola Secchiero, Veronica Tisato, Stefano Volpato, Nino Basaglia
BACKGROUND: Gait and mobility impairments affect the quality of life (QoL) of patients with progressive multiple sclerosis (MS). Robot-assisted gait training (RAGT) is an effective rehabilitative treatment but evidence of its superiority compared to other options is lacking. Furthermore, the response to rehabilitation is multidimensional, person-specific and possibly involves functional reorganization processes. The aims of this study are: (1) to test the effectiveness on gait speed, mobility, balance, fatigue and QoL of RAGT compared to conventional therapy (CT) in progressive MS and (2) to explore changes of clinical and circulating biomarkers of neural plasticity...
February 27, 2017: Trials
Alessandra Pompa, Giovanni Morone, Marco Iosa, Luca Pace, Sheila Catani, Paolo Casillo, Alessandro Clemenzi, Elio Troisi, Angelo Tonini, Stefano Paolucci, Maria Grazia Grasso
BACKGROUND: Robotic training is commonly used to assist walking training in patients affected by multiple sclerosis (MS) with non-conclusive results. OBJECTIVE: To compare the effect of robot-assisted gait training (RAGT) with that of conventional walking training (CWT) on gait competencies, global ability, fatigue and spasticity in a group of severely affected patients with MS. METHODS: A pilot, single-blind randomized controlled trial was conducted in 43 severe (Expanded Disability Status Scale (EDSS) score of 6-7...
April 2017: Multiple Sclerosis: Clinical and Laboratory Research
Sofia Straudi, Chiara Fanciullacci, Carlotta Martinuzzi, Claudia Pavarelli, Bruno Rossi, Carmelo Chisari, Nino Basaglia
BACKGROUND: Gait and mobility impairments are common in progressive multiple sclerosis (MS), leading to reduced quality of life (QoL). OBJECTIVE: In this randomized controlled study, we tested the effects of robot-assisted gait training (RAGT) and compared it to conventional physiotherapy, measuring walking ability, depression, fatigue, and QoL in patients with progressive MS and severe gait disability. METHODS: Fifty-two participants (Expanded Disability Status Scale score 6-7) completed the study protocol...
March 2016: Multiple Sclerosis: Clinical and Laboratory Research
Isabella Schwartz, Zeev Meiner
Regaining one's ability to walk is of great importance for neurological patients and is a major goal of all rehabilitation programs. Gait training of severely affected patients after the neurological event is technically difficult because of their motor weakness and balance disturbances. An innovative locomotor training that incorporates high repetitions of task-oriented practice by the use of body weight-supported treadmill training (BWSTT) was developed to overcome these obstacles. To facilitate the delivery of BWSTT, a motorized robotic driven gait orthosis (robotic-assisted gait training-RAGT) was developed...
May 2015: Annals of Biomedical Engineering
Marialuisa Gandolfi, Christian Geroin, Alessandro Picelli, Daniele Munari, Andreas Waldner, Stefano Tamburin, Fabio Marchioretto, Nicola Smania
BACKGROUND: Extensive research on both healthy subjects and patients with central nervous damage has elucidated a crucial role of postural adjustment reactions and central sensory integration processes in generating and "shaping" locomotor function, respectively. Whether robotic-assisted gait devices might improve these functions in Multiple sclerosis (MS) patients is not fully investigated in literature. PURPOSE: The aim of this study was to compare the effectiveness of end-effector robot-assisted gait training (RAGT) and sensory integration balance training (SIBT) in improving walking and balance performance in patients with MS...
2014: Frontiers in Human Neuroscience
Isabella Schwartz, Anna Sajin, Elior Moreh, Iris Fisher, Martin Neeb, Adina Forest, Adi Vaknin-Dembinsky, Dimitrios Karusis, Zeev Meiner
BACKGROUND: Preservation of locomotor activity in multiple sclerosis (MS) patients is of utmost importance. Robotic-assisted body weight-supported treadmill training is a promising method to improve gait functions in neurologically impaired patients, although its effectiveness in MS patients is still unknown. OBJECTIVE: To compare the effectiveness of robot-assisted gait training (RAGT) with that of conventional walking treatment (CWT) on gait and generalized functions in a group of stable MS patients...
June 2012: Multiple Sclerosis: Clinical and Laboratory Research
Claude Vaney, Brigitte Gattlen, Véronique Lugon-Moulin, André Meichtry, Rita Hausammann, Denise Foinant, Anne-Marie Anchisi-Bellwald, Cécilia Palaci, Roger Hilfiker
BACKGROUND: Robot-assisted gait training (RAGT) has been suggested as an intervention to improve walking capacity in patients with multiple sclerosis (MS). OBJECTIVE: This study aimed to evaluate whether RAGT (Lokomat) is superior to over-ground walking training in terms of quality of life, activity level, and gait. METHODS: A total of 67 patients with MS with the Expanded Disability Status Scale (EDSS) 3.0 to 6.5 were randomized to walking or RAGT, in addition to multimodal rehabilitation...
March 2012: Neurorehabilitation and Neural Repair
S Beer, B Aschbacher, D Manoglou, E Gamper, J Kool, J Kesselring
OBJECTIVE: To evaluate feasibility and perform an explanatory analysis of the efficacy of robot-assisted gait training (RAGT) in MS patients with severe walking disabilities (Expanded Disability Status Scale [EDSS] 6.0-7.5) in a pilot trial. METHODS: Prospective, randomized, controlled clinical trial comparing RAGT with conventional walking training (CWT) in a group of stable MS patients (n = 35) during an inpatient rehabilitation stay, 15 sessions over three weeks...
March 2008: Multiple Sclerosis: Clinical and Laboratory Research
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