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Orthopedic cement allergy

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https://www.readbyqxmd.com/read/26665256/acute-onset-of-vancomycin-anaphylaxis-with-disseminated-intravascular-coagulation-in-an-orthopedic-patient-despite-prior-repeated-exposure
#1
Brock Adams, Babak Roboubi, Robert Henshaw
Vancomycin is a glycopeptide antibiotic that exhibits bactericidal activity against gram-positive cocci. It is commonly recommended for surgical prophylaxis in cases of suspected bacterial resistance or penicillin allergy. There are 2 main types of hypersensitivity reactions associated with vancomycin. Red man syndrome is an anaphylactoid reaction caused by direct release of histamine. The second is an anaphylactic reaction, which is an immunoglobulin E-mediated response. We present the case of a 55-year-old woman with a history of metastatic giant cell tumor of the right proximal tibia...
December 2015: American Journal of Orthopedics
https://www.readbyqxmd.com/read/26411556/-addition-of-antibiotics-to-bone-cement-for-septic-prosthesis-exchange
#2
A Zahar, P Hannah
OBJECTIVE: Decontamination of periprosthetic infections by local antibiotic therapy with maximum dosing. Commercially available bone cement is used as the carrier material. Bone cement containing antibiotics is an established procedure in orthopedics for the fixation of cemented implants in artificial joint replacement. It is part of the primary and revision endoprosthetic treatment together with systemic administration of antibiotics for routine local antibiotic prophylaxis. INDICATIONS: Bone cement containing antibiotics is used in the treatment of periprosthetic infections for two-stage septic exchange operations as a spacer in the prosthesis-free interval and for reimplantation in the second operation...
April 2016: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/24941403/evaluation-and-management-of-metal-hypersensitivity-in-total-joint-arthroplasty-a-systematic-review
#3
REVIEW
Michael Amini, Wesley H Mayes, Alice Tzeng, Tony H Tzeng, Khaled J Saleh, William M Mihalko
Metal hypersensitivity has been an identified problem in orthopedics for nearly half a century, but its implications remain unclear. Establishing which total joint arthroplasty (TJA) candidates may do poorly with conventional implants and which patients would benefit from revision to an allergen-free implant remains challenging. Our systematic search of the MEDLINE database identified 52 articles for inclusion in our review. Case reports revealed that half of patients presented with pain and swelling, while only one-third presented with cutaneous symptoms...
2014: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/18210082/-orthopedic-surgical-implants-and-allergies-joint-statement-by-the-implant-allergy-working-group-ak-20-of-the-dgooc-german-association-of-orthopedics-and-orthopedic-surgery-dkg-german-contact-dermatitis-research-group-and-dgaki-german-society-for-allergology
#4
COMPARATIVE STUDY
P Thomas, A Schuh, J Ring, M Thomsen
Materials used in osteosynthesis or artificial joint replacement are usually well tolerated. Complaints after such operations are mostly related to infection or mechanical problems but may also be caused by allergic reactions. The latter encompass skin changes, e.g., eczema, delayed wound/bone healing, recurrent effusion, pain, or implant loosening. In contrast to the high incidence of cutaneous metal contact allergy, allergies associated with implants are a rare condition. However, epidemiological data on the incidence of implant-related allergic reactions are still missing...
January 2008: Der Orthopäde
https://www.readbyqxmd.com/read/18210000/-orthopedic-surgical-implants-and-allergies-joint-statement-by-the-implant-allergy-working-group-ak-20-of-the-dgooc-german-association-of-orthopedics-and-orthopedic-surgery-dkg-german-contact-dermatitis-research-group-and-dgaki-german-society-for-allergology
#5
P Thomas, A Schuh, J Ring, M Thomsen
Materials used in osteosynthesis or artificial joint replacement are usually well tolerated. Complaints after such operations are mostly related to infection or mechanical problems but may also be caused by allergic reactions. The latter encompass skin changes, e.g., eczema, delayed wound/bone healing, recurrent effusion, pain, or implant loosening. In contrast to the high incidence of cutaneous metal contact allergy, allergies associated with implants are a rare condition. However, epidemiological data on the incidence of implant-related allergic reactions are still missing...
March 2008: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/2957888/skin-protection-against-methylmethacrylate
#6
COMPARATIVE STUDY
E Darre, P Vedel, J S Jensen
Ordinary surgical rubber gloves are penetrated by methylmethacrylate monomer (MMA) in less than 1 minute, as demonstrated by gas chromatographic measurements. A three-layered PVP glove, 0.07 mm thick--consisting of an outer layer of polyethylene, an intermediary layer of ethylene vinyl alcohol copolymer, and an inner layer of polyethylene--was impervious for 20 minutes, whereas a viton-butyl rubber glove, 0.27 mm thick, was impervious for 15 minutes. The PVP glove is recommended to orthopedic surgeons, nurses, and other handling acrylic bone cements to avoid sensitization, and is especially recommended to persons with known contact allergy to MMA...
June 1987: Acta Orthopaedica Scandinavica
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